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Displaying drugs 501 - 525 of 10837 in total
Sodium citrate is the sodium salt of citric acid. It is white, crystalline powder or white, granular crystals, slightly deliquescent in moist air, freely soluble in water, practically insoluble in alcohol. Like citric acid, it has a sour taste. From the medical point of view, it is used as alkalinizing...
Approved
Investigational
Matched Mixtures name: … Cpda-1 ... Cpda-1 ... Cpda-1
A vasoconstrictor found in ergot of Central Europe. It is an alpha-1 selective adrenergic agonist and is commonly used in the treatment of migraine disorders.
Approved
Matched Iupac: … diazatricyclo[7.3.0.0^{2,6}]dodecan-4-yl]-6-methyl-6,11-diazatetracyclo[7.6.1.0^{2,7}.0^{12,16}]hexadeca-1( …
Matched Description: … It is an alpha-1 selective adrenergic agonist and is commonly used in the treatment of migraine disorders …
Matched Mixtures name: … ERGOTAMINA/CAFEINA 1/100 MG ... CAFERGOT 1 MG/100 MG TABLET, 30 ADET ... ERGOTAMINA 1 MG + CAFEINA 100 MG TABLETAS …
Matched Categories: … Adrenergic alpha-1 Receptor Antagonists …
Melphalan flufenamide, also known as melflufen or J1, is a prodrug of melphalan.[A230123,L32173] Melphalan flufenamide is more readily uptaken by cells than melphalan, and is cleaved to the active metabolite by aminopeptidases. In vitro models show that melphalan is 10 to hundreds of times more potent than melphalan. The increased...
Approved
Withdrawn
Diiodohydroxyquinoline, also known as uidoquinol and iodoquinol, is a quinoline derivative that can be used in the treatment of amoebiasis. The exact mechanism of action is unknown. Iodoquinol is not currently available in any FDA-approved products.
Approved
Matched Mixtures name: … Iodoquinol 1% - Hydrocortisone Acetate 2% - Aloe Polysaccharides 1% ... Hydrocortisone 2.5% / Iodoquinol 1% / Ketoconazole 2% …
Fibrodysplasia Ossificans Progressiva (FOP), with an estimated worldwide prevalence of one in 2 million individuals, is an exceptionally rare genetic disorder. FOP is caused by a gain-of-function mutation in the ACVR1/ALK2 gene which results in progressive heterotopic ossification, a process wherein connective tissues (e.g. skeletal muscle, ligaments, tendons) are replaced...
Approved
Investigational
Matched Iupac: … 4-[(1E)-2-{5,5,8,8-tetramethyl-3-[(1H-pyrazol-1-yl)methyl]-5,6,7,8-tetrahydronaphthalen-2-yl}ethenyl] …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Tapinarof is a novel, first-in-class, small-molecule AhR agonist that is indicated for the treatment of adult psoriasis. It is available as a topical cream to be applied to the affected area once daily.[L41845, A248790] Tapiranof was first discovered as a metabolite (3,5-dihydroxy-4-isopropylstilbene) produced in Photorhabdus luminescens, a gram-negative bacillus that...
Approved
Investigational
Simeprevir is a hepatitis C virus (HCV) NS3/4A protease inhibitor indicated in patient's with HCV genotype 1 for the treatment of chronic hepatitis C virus (HCV) infection. HCV is a single-stranded RNA virus that is categorized into nine distinct genotypes, with genotype 1 being the most common in the United...
Approved
Matched Description: … or PEG-Interferon/ribavirin combination therapy for genotype 1 or 4. ... Simeprevir is a hepatitis C virus (HCV) NS3/4A protease inhibitor indicated in patient's with HCV genotype 1 ... HCV is a single-stranded RNA virus that is categorized into nine distinct genotypes, with genotype 1
Matched Salts cas: … 1241946-89-3 …
Technetium Tc-99m sestamibi (commonly sestamibi) is a pharmaceutical agent used in nuclear medicine imaging. The drug is a coordination complex consisting of the radioisotope technetium-99m bound to six methoxyisobutylisonitrile (MIBI) ligands, hence the name sesta (6) MIBI.. Following intravenous injection of the drug, Technetium Tc-99m sestamibi is taken up by...
Approved
Investigational
Matched Iupac: … technetium(1+) ion hexakis(1-isocyano-2-methoxy-2-methylpropane) …
Matched Description: … Currently available within a preparation kit for injection, Technetium Tc 99m Sestamibi is indicated for: 1) …
Arbutamine, administered through a closed-loop, computer-controlled drug-delivery system, is indicated to elicit acute cardiovascular responses, similar to those produced by exercise, in order to aid in diagnosing the presence or absence of coronary artery disease in patients who cannot exercise adequately .
Approved
Matched Iupac: … 4-[(1R)-1-hydroxy-2-{[4-(4-hydroxyphenyl)butyl]amino}ethyl]benzene-1,2-diol …
Matched Categories: … Adrenergic beta-1 Receptor Agonists …
Levonordefrin acts as a topical nasal decongestant and vasoconstrictor, most often used in dentistry.
Approved
Matched Iupac: … 4-[(1R,2S)-2-amino-1-hydroxypropyl]benzene-1,2-diol …
Matched Mixtures name: … 2% Polocaine Dental With Levonordefrin 1:20,000 …
Lifitegrast is a FDA approved drug for the treatment of keratoconjunctivitis sicca (dry eye syndrome). It is a tetrahydroisoquinoline derivative and lymphocyte function-associated antigen-1 ( LFA-1) antagonist that was discovered through the rational design process. The ophthalmic solution was approved in July, 2016 under the trade name Xiidra. It has...
Approved
Matched Iupac: … (2S)-2-{[2-(1-benzofuran-6-carbonyl)-5,7-dichloro-1,2,3,4-tetrahydroisoquinolin-6-yl]formamido}-3-(3- …
Matched Description: … It is a tetrahydroisoquinoline derivative and lymphocyte function-associated antigen-1 ( LFA-1) antagonist …
Matched Categories: … Lymphocyte Function-Associated Antigen-1 ... Lymphocyte Function-Associated Antigen-1 Antagonist ... Lymphocyte Function-Associated Antigen-1 Antagonists …
Poliovirus type 3 antigen is a suspension of poliovirus Type 3 (Saukett) used in the active immunization of infants (as young as 6 weeks of age), children, and adults for the prevention of poliomyelitis caused by poliovirus Type 3. The vaccine contains purified and inactivated poliovirus type 3 that were...
Approved
Investigational
Matched Mixtures name: … HEXAXIM 0.5 ML IM ENJEKSİYONLUK SÜSPANSİYON İÇEREN FLAKON, 1 ADET ... TETRAXIM 0.5 ML IM ENJEKSİYON İÇİN SÜSPANSİYON İÇEREN KULLANIMA HAZIR ENJEKTÖR, 1 ADET ... ADACEL POLIO 0,5 ML IM ENJEKSİYON İÇİN SÜSPANSİYON İÇEREN KULLANIMA HAZIR ENJEKTÖR, 1 ADET …
Glycerol phenylbutyrate is a nitrogen-binding agent. Chemically, it is a triglyceride in which three molecules of phenylbutyrate are linked to a glycerol backbone. FDA approved on February 1, 2013.
Approved
Matched Description: … FDA approved on February 1, 2013. …
Oxyquinoline is a heterocyclic phenol and derivative of quinoline with antiseptic, disinfectant, and pesticide properties. It is used as a stabilizer for hydrogen peroxide, where it is sometimes added in cosmetic products.
Approved
Vet approved
Abaloparatide is an N-terminal analog of parathyroid hormone-related protein (PTHrP) and an agonist at the parathyroid hormone type 1 (PTH1) receptor. It is a synthetic 34 amino acid peptide with 41% homology to human parathyroid hormone 1-34 and human PTHrP 1-34. Abaloparatide and PTHrP share the first 21 amino acids...
Approved
Investigational
Matched Description: … human PTHrP 1-34. ... parathyroid hormone-related protein (PTHrP) [A256778] and an agonist at the parathyroid hormone type 1 ... [L740] It is a synthetic 34 amino acid peptide with 41% homology to human parathyroid hormone 1-34 and …
Trofinetide is a novel synthetic analog of glypromate, also known as glycine–proline–glutamate (GPE), a naturally occurring protein in the brain and the N-terminal tripeptide of insulin-like growth factor 1 (IGF-1). Trofinetide was approved by the FDA on March 10, 2023, for the treatment of Rett syndrome,[L45718,L45748] which is an X-linked...
Approved
Investigational
Matched Iupac: … (2S)-2-{[(2S)-1-(2-aminoacetyl)-2-methylpyrrolidin-2-yl]formamido}pentanedioic acid …
Matched Description: … (IGF-1). ... naturally occurring protein in the brain and the N-terminal tripeptide of insulin-like growth factor 1
An antiandrogen with about the same potency as cyproterone in rodent and canine species.
Approved
Investigational
Approved
Matched Mixtures name: … BEXSERO 0,5 ML İM ENJEKSİYONLUK SÜSPANSİYON İÇEREN KULLANIMA HAZIR ENJEKTÖR, 1 ADET 2 İĞNELİ ... BEXSERO 0,5 ML İM ENJEKSİYONLUK SÜSPANSİYON İÇEREN KULLANIMA HAZIR ENJEKTÖR, 1 ADET İĞNESİZ …
Approved
Matched Mixtures name: … BEXSERO 0,5 ML İM ENJEKSİYONLUK SÜSPANSİYON İÇEREN KULLANIMA HAZIR ENJEKTÖR, 1 ADET 2 İĞNELİ ... BEXSERO 0,5 ML İM ENJEKSİYONLUK SÜSPANSİYON İÇEREN KULLANIMA HAZIR ENJEKTÖR, 1 ADET İĞNESİZ …
Approved
Matched Mixtures name: … BEXSERO 0,5 ML İM ENJEKSİYONLUK SÜSPANSİYON İÇEREN KULLANIMA HAZIR ENJEKTÖR, 1 ADET 2 İĞNELİ ... BEXSERO 0,5 ML İM ENJEKSİYONLUK SÜSPANSİYON İÇEREN KULLANIMA HAZIR ENJEKTÖR, 1 ADET İĞNESİZ …
Methoxy polyethylene glycol-epoetin beta is a chemically synthesised Erythropoiesis Stimulating Agent (ESA) with a longer half-life than erythropoietin. ESA is used to increase synthesis of red blood cells to treat chronic kidney disease associated anemia.
Approved
Matched Products: … MIRCERA 360 MCG/0.6 ML SC/IV ENJEKSİYONLUK ÇÖZELTİ İÇEREN FLAKON, 1 ADET ... MIRCERA 100 MCG/ML SC/IV ENJEKSİYONLUK ÇÖZELTİ İÇEREN FLAKON, 1 ADET …
Sparsentan is a dual antagonist of the endothelin type A receptor (ETAR) and the angiotensin II (Ang II) type 1 receptor (AT1R) with a similar affinity for both (9.3 nM for ETAR and 0.8 nM for AT1R).[A257330,L45300] Sparsentan is first in its class and orally active, and was created by...
Approved
Investigational
Matched Iupac: … 4'-({2-butyl-4-oxo-1,3-diazaspiro[4.4]non-1-en-3-yl}methyl)-N-(4,5-dimethyl-1,2-oxazol-3-yl)-2'-(ethoxymethyl …
Matched Description: … AT1R). ... antagonist of the endothelin type A receptor (ETAR) and the angiotensin II (Ang II) type 1 ... receptor (AT1R) with a similar affinity for both (9.3 nM for ETAR and 0.8 nM for …
Matched Categories: … Angiotensin II Type 1 Receptor Blockers ... Dual Endothelin Type A Receptor/Ang II Subtype 1 Receptor Antagonist (DEARA) …
Aripiprazole lauroxil is a long-acting injectable atypical antipsychotic drug used in the treatment of schizophrenia in adult patients. It is a prodrug of aripiprazole, which acts as a partial agonist at the D2 and 5-HT1A receptors, and as an antagonist at the 5-HT2A receptors . Affecting about 1% of the...
Approved
Investigational
Matched Iupac: … (7-{4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butoxy}-2-oxo-1,2,3,4-tetrahydroquinolin-1-yl)methyl dodecanoate …
Matched Description: … Affecting about 1% of the adult population in the United States and approximately 26 million people worldwide …
Matched Categories: … Adrenergic alpha-1 Receptor Antagonists ... Heterocyclic Compounds, 1-Ring …
Dexibuprofen, S(+)-ibuprofen, is a non-steroidal anti-inflammatory drug (NSAID). It is a pharmacologically effective enantiomer of racemic ibuprofen that differs in physicochemical properties. It is proposed to be more pharmacologically active and tolerable with a better safety profile than ibuprofen due to higher concentration of active S enantiomer. Dexibuprofen has a...
Approved
Investigational
Matched Products: … EXER® 1% SUSPENSION …
Zinc gluconate is a zinc salt of gluconic acid comprised of two gluconic acid molecules for each zinc cation (2+). Zinc gluconate is a generally recognized as safe (GRAS) substance by FDA . It is available as a trace mineral supplement and over the counter as a lozenge form for...
Approved
Vet approved
Matched Products: … Zink Aguettant 1 mg/ml Konzentrat zur Herstellung einer Infusionslösung …
Displaying drugs 501 - 525 of 10837 in total