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Displaying drugs 501 - 525 of 4882 in total
beta-Alanine is an amino acid formed in vivo by the degradation of dihydrouracil and carnosine. Since neuronal uptake and neuronal receptor sensitivity to beta-alanine have been demonstrated, the compound may be a false transmitter replacing GAMMA-AMINOBUTYRIC ACID. A rare genetic disorder, hyper-beta-alaninemia, has been reported.
Experimental
Matched Synonyms: … 3-aminopropanoic acid ... 3-aminopropionic acid ... β-aminopropionic acid
Matched Iupac: … 3-aminopropanoic acid
Matched Description: … beta-Alanine is an amino acid formed in vivo by the degradation of [dihydrouracil] and [carnosine]. ... may be a false transmitter replacing GAMMA-AMINOBUTYRIC ACID. ... Since neuronal uptake and neuronal receptor sensitivity to beta-alanine have been demonstrated, the compound …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids
An oxidation product of tryptophan metabolism. It may be a free radical scavenger and a carcinogen.
Experimental
Matched Synonyms: … 3-Oxyanthranilic acid ... 2-Amino-3-hydroxy-benzoic acid ... 2-Amino-3-Hydroxybenzoic Acid
Matched Name: … 3-hydroxyanthranilic acid
Matched Iupac: … 2-amino-3-hydroxybenzoic acid
Matched Description: … It may be a free radical scavenger and a carcinogen. …
Matched Categories: … Acids, Carbocyclic ... Carboxylic Acids ... Hydroxy Acids
Experimental
Matched Synonyms: … (2S,3R)-2,3-Diaminobutanoic acid ... L-Threo-alpha,beta-diaminobutyric acid ... L-threo-2,3-diamino-butyric acid
Matched Name: … (2S)-2,3-Diaminobutanoic acid
Matched Iupac: … (2S,3R)-2,3-diaminobutanoic acid
Bazlitoran is under investigation in clinical trial NCT02092909 (Phase 1/2 Dose Escalation Study in Patients With Relapsed or Refractory Waldenstrom's Macroglobulinemia).
Investigational
Matched Synonyms: … Antagonist of the endosomal Toll-like receptors (TLRs) 7, 8, and 9 ... ALL-P-AMBO-2'-DEOXY-P-THIOCYTIDYLYL-(3'->5')-P-THIOTHYMIDYLYL-(3'->5')-2'-DEOXY-P-THIOADENYLYL-(3'->5 ... ')-P-THIOTHYMIDYLYL-(3'->5')-2'-DEOXY-P-THIOCYTIDYLYL-(3'->5')-P-THIOTHYMIDYLYL-(3'->5')-2'-O-METHYL-P-THIOGUANYLYL …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Experimental
Matched Synonyms: … alpha-Hydroxy-gamma-(methylthio)butyric acid ... alpha-Hydroxy-gamma-(methylmercapto)butyric acid ... 2-Hydroxy-4-(methylthio) butanoic acid
Matched Iupac: … 2-hydroxy-4-(methylsulfanyl)butanoic acid
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids ... Amino Acids, Neutral ... Amino Acids, Sulfur …
Experimental
Matched Synonyms: … 3-(4-diethylamino-2-hydroxy-phenyl)-2-methyl-propionic acid ... alpha-MHDAC …
Matched Name: … alpha-Methyl-2-hydroxy-4-diethylaminocinnamic acid
Matched Iupac: … (2E)-3-[4-(diethylamino)-2-hydroxyphenyl]-2-methylprop-2-enoic acid
Matched Categories: … Carboxylic Acids ... Acids, Carbocyclic …
Levoleucovorin is the enantiomerically active form of Folinic Acid (also known as 5-formyl tetrahydrofolic acid or leucovorin). Commercially available leucovorin is composed of a 1:1 racemic mixture of the dextrorotary and levorotary isomers, while levoleucovorin contains only the pharmacologically active levo-isomer. In vitro, the levo-isomer has been shown to be...
Approved
Investigational
Matched Synonyms: … L-Folinic acid ... (6S)-Folinic acid ... Levofolinic acid
Matched Iupac: … -amino-5-formyl-4-oxo-1,4,5,6,7,8-hexahydropteridin-6-yl]methyl}amino)phenyl]formamido}pentanedioic acid
Matched Description: … This important pathway, which is required for de novo synthesis of nucleic acids and amino acids, is ... Levoleucovorin is the enantiomerically active form of Folinic Acid (also known as 5-formyl tetrahydrofolic ... Folic acid is an essential B vitamin required by the body for the synthesis of purines, pyrimidines, …
Matched Salts cas: … 419573-16-3
Matched Categories: … Folic Acid and Derivatives ... Folic Acid Analogues ... Enzymes and Coenzymes …
Setogepram is under investigation in clinical trial NCT03184584 (Open-Label Rollover Study of PBI 4050 in Subjects With Alström Syndrome).
Investigational
Matched Synonyms: … 3-Pentylbenzenacetic acid ... 2-(3-Pentylphenyl)acetic acid
Matched Iupac: … 2-(3-pentylphenyl)acetic acid
Matched Salts cas: … 1254472-97-3
Matched Categories: … Fatty Acids ... Fatty Acids, Volatile ... Acids, Acyclic ... Carboxylic Acids
Experimental
Matched Synonyms: … 3-(4-Hydroxyphenyl)propionic acid ... 3-(p-hydroxyphenyl)propionic acid ... Phloretic acid
Matched Name: … Phloretic acid
Matched Iupac: … 3-(4-hydroxyphenyl)propanoic acid
Matched Categories: … Carboxylic Acids ... Acids, Carbocyclic …
An anti-inflammatory analgesic and antipyretic highly bound to plasma proteins. It is pharmacologically similar to aspirin, but causes less gastrointestinal bleeding.
Approved
Matched Synonyms: … 3-phenoxyhydratropic acid ... 2-(3-phenoxyphenyl)propionic acid ... (±)-2-(3-phenoxyphenyl)propionic acid
Matched Iupac: … 2-(3-phenoxyphenyl)propanoic acid
Matched Description: … An anti-inflammatory analgesic and antipyretic highly bound to plasma proteins. …
Matched Salts cas: … 34691-31-1 …
Matched Categories: … Acids, Carbocyclic ... Carboxylic Acids ... Arylpropionic acid NSAIDS ... Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids …
Experimental
Matched Synonyms: … alpha-Dimorphecolic acid ... (9S,10E,12Z)-9-hydroxyoctadeca-10,12-dienoic acid
Matched Iupac: … (9S,10E,12Z)-9-hydroxyoctadeca-10,12-dienoic acid
Cefepime is a fourth-generation cephalosporin antibiotic developed in 1994. Cefepime is active against Gram-positive and Gram-negative bacteria, and has greater activity against both compared to third-generation antibiotics.[A2457,A249050] Cefepime is normally used to treat severe nosocomial pneumonia and infections caused by multi-resistant microorganisms such as Pseudomonas aeruginosa, and is also indicated...
Approved
Investigational
Matched Synonyms: … (6R,7R)-7-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino}-3-[(1-methylpyrrolidinium …
Matched Iupac: … 1,3-thiazol-4-yl)-2-(methoxyimino)acetamido]-2-carboxylato-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3- …
Matched Description: … Cefepime is active against Gram-positive and Gram-negative bacteria, and has greater activity against ... [A2457,A249050] Cefepime is normally used to treat severe nosocomial pneumonia and infections caused ... by multi-resistant microorganisms such as _Pseudomonas aeruginosa_, and is also indicated for the empirical …
Matched Categories: … cefepime and amikacin …
Matched Products: … Cefepime Hydrochloride and Dextrose …
One of the non-essential amino acids commonly occurring in the L-form. It is found in animals and plants, especially in sugar cane and sugar beets. It may be a neurotransmitter.
Approved
Nutraceutical
Matched Synonyms: … Aspartic acid ... L-Aspartic acid ... Acidum asparticum …
Matched Name: … Aspartic acid
Matched Iupac: … (2S)-2-aminobutanedioic acid
Matched Description: … One of the non-essential amino acids commonly occurring in the L-form. ... It is found in animals and plants, especially in sugar cane and sugar beets. …
Matched Mixtures name: … Premasol - sulfite-free (Amino Acid) ... Premasol - sulfite-free (Amino Acid) ... PRIMENE 10% AMINO ACID INTRAVENOUS INFUSION …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids, Acidic ... Amino Acids ... Amino Acids, Dicarboxylic ... Excitatory Amino Acids
Approved
Vet approved
Matched Iupac: … 2-[(1R,3aS,3bS,9aR,9bS,10S,11aS)-1,10-dihydroxy-9a,11a-dimethyl-7-oxo-1H,2H,3H,3aH,3bH,4H,5H,7H,8H,9H …
Matched Mixtures name: … KORTOS KREM, 30 G ... TIOZONE KREM, 30 G ... RECTALGİN KREM, 30 GRAM …
Matched Categories: … Hydrocortisone and derivatives ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … American Safety and First Aid ... HIPOKORT %0.5 KREM 30 G ... HIPOKORT %0.5 MERHEM, 30 GR …
Triamcinolone is a corticosteroid used to treat various inflammatory conditions in the body from allergic rhinitis to acute exacerbations of multiple sclerosis. Triamcinolone can be used as a one time adjunct treatment of osteoarthritic knee pain, or first line as a topical treatment of corticosteroid responsive dermatoses. Triamcinolone is more...
Approved
Vet approved
Matched Iupac: … ,3H,3aH,3bH,4H,5H,7H,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-7-one ... (1S,2R,3aS,3bS,9aS,9bR,10S,11aS)-9b-fluoro-1,2,10-trihydroxy-1-(2-hydroxyacetyl)-9a,11a-dimethyl-1H,2H …
Matched Description: … Triamcinolone is more commonly seen in the forms triamcinolone hexacetonide, triamcinolone acetonide, and ... [L8246,L8249,L8252,L8255,L8258,L8261,L8264] Triamcinolone was granted FDA approval on 3 December 1957 …
Matched Mixtures name: … Pro-C-Dure 3 Kit ... AFTOJEL % 0,1 + %3 JEL (5 G) ... Aureocort 1 mg/g + 30 mg/g Salbe …
Matched Categories: … Alimentary Tract and Metabolism ... Sex Hormones and Insulins ... triamcinolone and antiseptics ... triamcinolone and antibiotics ... triamcinolone and antiinfectives …
Matched Products: … Up and Up Nasal Allergy ... Foster and Thrive 24 Hour Nasal Allergy ... แอคซิน 3 ครีม …
Sparfosic acid is a solid. This compound belongs to the n-acyl-alpha amino acids. These are compounds containing an alpha amino acid which bears an acyl group at the terminal nitrogen atom. This substance is known to target aspartate carbamoyltransferase catalytic chain and CAD protein.
Experimental
Matched Synonyms: … Acidum sparfosicum ... Sparfosic acid ... N-(phosphonacetyl)-L-aspartic acid
Matched Name: … Sparfosic acid
Matched Iupac: … (2S)-2-(2-phosphonoacetamido)butanedioic acid
Matched Description: … Sparfosic acid is a solid. This compound belongs to the n-acyl-alpha amino acids. ... These are compounds containing an alpha amino acid which bears an acyl group at the terminal nitrogen ... This substance is known to target aspartate carbamoyltransferase catalytic chain and CAD protein. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids, Acidic ... Amino Acids ... Acids, Acyclic ... Carboxylic Acids
Flunarizine is a selective calcium entry blocker with calmodulin binding properties and histamine H1 blocking activity. It is effective in the prophylaxis of migraine, occlusive peripheral vascular disease, vertigo of central and peripheral origin, and as an adjuvant in the therapy of epilepsy.
Approved
Matched Synonyms: … 1-[bis(4-fluorophenyl)methyl]-4-[(2E)-3-phenylprop-2-en-1-yl]piperazine …
Matched Iupac: … 1-[bis(4-fluorophenyl)methyl]-4-[(2E)-3-phenylprop-2-en-1-yl]piperazine …
Matched Description: … peripheral origin, and as an adjuvant in the therapy of epilepsy. ... Flunarizine is a selective calcium entry blocker with calmodulin binding properties and histamine H1 ... effective in the prophylaxis of migraine, occlusive peripheral vascular disease, vertigo of central and
Matched Categories: … Calcium-Regulating Hormones and Agents …
Matched Products: … FLUNARIZIN ACIS 5MG ... FLUNARIZIN ACIS 10MG …
L-cysteic acid is a beta-sulfoalanine. It is an amino acid with a C-terminal sulfonic acid group which has been isolated from human hair oxidized with permanganate. It occurs normally in the outer part of the sheep's fleece, where the wool is exposed to light and weather.
Experimental
Matched Synonyms: … 2-Amino-3-sulfopropionic acid ... (2R)-2-amino-3-sulfopropanoic acid ... Cysteric acid
Matched Name: … L-cysteic acid
Matched Iupac: … (2R)-2-amino-3-sulfopropanoic acid
Matched Description: … L-cysteic acid is a beta-sulfoalanine. ... It is an amino acid with a C-terminal sulfonic acid group which has been isolated from human hair oxidized ... It occurs normally in the outer part of the sheep's fleece, where the wool is exposed to light and weather …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids ... Amino Acids, Sulfur …
A small colorless crystal used as an anticonvulsant, a cathartic, and an electrolyte replenisher in the treatment of pre-eclampsia and eclampsia. It causes direct inhibition of action potentials in myometrial muscle cells. Excitation and contraction are uncoupled, which decreases the frequency and force of contractions. (From AMA Drug Evaluations Annual,...
Approved
Investigational
Vet approved
Matched Description: … treatment of pre-eclampsia and eclampsia. ... Excitation and contraction are uncoupled, which decreases the frequency and force of contractions. ... A small colorless crystal used as an anticonvulsant, a cathartic, and an electrolyte replenisher in the …
Matched Mixtures name: … Sodium Sulfate, Potassium Sulfate and Magnesium Sulfate ... Sodium Sulfate, Potassium Sulfate and Magnesium Sulfate ... Sodium Sulfate, Potassium Sulfate and Magnesium Sulfate …
Matched Categories: … Sulfur Acids ... Sulfuric Acids ... Alimentary Tract and Metabolism ... Blood and Blood Forming Organs ... Blood Substitutes and Perfusion Solutions …
Matched Products: … Spearmint and Menthol scented Natural Epsom Salt …
Experimental
Matched Synonyms: … 3-morpholinopropanesulfonic acid ... Morpholinopropane sulfonic acid
Matched Name: … 3-(N-morpholino)propanesulfonic acid
Matched Iupac: … 3-(morpholin-4-yl)propane-1-sulfonic acid
Nitrendipine is a calcium channel blocker with marked vasodilator action. It is an effective antihypertensive agent and differs from other calcium channel blockers in that it does not reduce glomerular filtration rate and is mildly natriuretic, rather than sodium retentive.
Approved
Investigational
Matched Synonyms: … 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic acid ethyl methyl ester …
Matched Iupac: … 3-ethyl 5-methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate …
Matched Description: … It is an effective antihypertensive agent and differs from other calcium channel blockers in that it ... does not reduce glomerular filtration rate and is mildly natriuretic, rather than sodium retentive. …
Matched Mixtures name: … ENEAS 10/20 MG TABLET, 30 ADET ... ENIT 10 MG/20 MG TABLET, 30 ADET …
Matched Categories: … ACE Inhibitors and Calcium Channel Blockers ... Calcium-Regulating Hormones and Agents ... enalapril and nitrendipine …
Matched Products: … NITREN ACIS 20MG …
Experimental
Matched Synonyms: … cis-1-Carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1-propanoic acid ... (1s,4s)-prephenic acid ... cis-prephenic acid
Matched Name: … Prephenic acid
Matched Iupac: … (1s,4s)-1-(2-carboxy-2-oxoethyl)-4-hydroxycyclohexa-2,5-diene-1-carboxylic acid
Matched Categories: … Carboxylic Acids ... Acids, Carbocyclic …
A cephalorsporin antibiotic that is no longer commonly used.
Approved
Matched Synonyms: … 7-(2-D-alpha-Aminophenylacetamido)cephalosporanic acid ... 7-(D-alpha-Aminophenyl-acetamido)cephalosporanic acid ... 7-(D-2-Amino-2-phenylacetamido)-3-acetoxymethyl-delta(sup3)-cephem-4-carboxylic acid
Matched Iupac: … 2-ene-2-carboxylic acid ... (6R,7R)-3-[(acetyloxy)methyl]-7-[(2R)-2-amino-2-phenylacetamido]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct- …
An essential amino acid occurring naturally in the L-form, which is the active form. It is found in eggs, milk, gelatin, and other proteins.
Approved
Nutraceutical
Matched Synonyms: … L-alpha-amino-beta-hydroxybutyric acid ... 2-Amino-3-hydroxybutyric acid ... L-2-Amino-3-hydroxybutyric acid
Matched Iupac: … (2S,3R)-2-amino-3-hydroxybutanoic acid
Matched Description: … An essential amino acid occurring naturally in the L-form, which is the active form. ... It is found in eggs, milk, gelatin, and other proteins. …
Matched Mixtures name: … Aminosyn II and Dextrose ... Aminosyn II and Dextrose ... Travasol Amino Acid Inj 8.5% …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids ... Amino Acids, Neutral ... Amino Acids, Essential ... Proteinogenic Amino Acids
Primary biliary cirrhosis, or PBC, is a progressive and chronic condition that leads to hepatic injury often resulting in end-stage liver failure that requires liver transplantation. Obeticholic acid is a farnesoid-X receptor (FXR) agonist used to treat this condition, possibly allowing for increased survival. In 2016, it was granted approval...
Approved
Matched Synonyms: … 6-alpha-ethylchenodeoxycholic acid ... (,5β,6α,7α)-6-ethyl-3,7-dihydroxycholan-24-oic acid ... Obeticholic acid
Matched Name: … Obeticholic acid
Matched Iupac: … [a]phenanthren-1-yl]pentanoic acid ... (4R)-4-[(1R,3aS,3bS,4R,5R,5aS,7R,9aS,9bS,11aR)-5-ethyl-4,7-dihydroxy-9a,11a-dimethyl-hexadecahydro-1H-cyclopenta …
Matched Description: … The NDA from Intercept Pharmaceuticals was approved in November 2019 and obeticholic acid is expected ... Primary biliary cirrhosis, or PBC, is a progressive and chronic condition that leads to hepatic injury ... in patients with PBC and advanced cirrhosis (e.g. those with portal hypertension or hepatic decompensation …
Matched Categories: … Bile Acids and Salts ... Bile acids and derivatives ... Cholic Acids ... Bile Acid Preparations ... obeticholic acid
Displaying drugs 501 - 525 of 4882 in total