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Displaying drugs 501 - 525 of 1173 in total
Immunoglobulin G1, anti-(human CD30 (antigen)) (human monoclonal MDX-060 heavy chain), disulfide with human monoclonal MDX-060 light chain, dimer. Molecular weight is approximately 170,000 daltons. In phase I/II clinical trials for treatment of CD30+ lymphomas.
Investigational
Matched Synonyms: … 5F11 monoclonal antibody
Matched Categories: … Amino Acids, Peptides, and Proteins …
Experimental
Investigational
Matched Synonyms: … Sulfate ... Sulfate(2-) ... Sulfate dianion …
Matched Name: … Sulfate ion …
Matched Iupac: … sulfate
Matched Categories: … Sulfates
Anti-a33 fully-human monoclonal antibody is under investigation in clinical trial NCT00838578 (Phase I/II Study of KRN330 Plus Irinotecan in Patients With Metastatic Colorectal Cancer).
Investigational
Matched Synonyms: … ANTI-A33 FULLY-HUMAN MONOCLONAL ANTIBODY ... HUMAN MONOCLONAL ANTIBODY TO COLON CANCER ANTIGEN A33 …
Matched Description: … Anti-a33 fully-human monoclonal antibody is under investigation in clinical trial NCT00838578 (Phase …
Matched Categories: … Amino Acids, Peptides, and Proteins …
There is a great deal of evidence indicating that vascular endothelial growth factor (VEGF) is important for the survival and proliferation of cancer cells.[A192939,A192837,A192891,A193275] VEGF plays an important role in angiogenesis, lymphangiogenesis, and tumor growth, which are all factors that contribute to its attractiveness as a therapeutic target for anti-cancer...
Approved
Investigational
Matched Synonyms: … Anti-VEGF monoclonal antibody ... Anti-VEGF Humanized Monoclonal Antibody
Matched Description: … [A193272,A193275] It is a humanized monoclonal IgG antibody, and inhibits angiogenesis by binding and ... of evidence indicating that vascular endothelial growth factor (VEGF) is important for the survival and ... [A192939,A192837,A192891,A193275] VEGF plays an important role in angiogenesis, lymphangiogenesis, and
Matched Categories: … MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES ... Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Vascular Endothelial Growth Factor-directed Antibody Interactions …
A complex of related glycopeptide antibiotics from Streptomyces verticillus consisting of bleomycin A2 and B2 (B2 CAS # 9060-10-0). It inhibits DNA metabolism and is used as an antineoplastic, especially for solid tumors. Bleomycin A2 is used as the representative structure for Bleomycin.
Approved
Investigational
Matched Description: … of related glycopeptide antibiotics from Streptomyces verticillus consisting of bleomycin A2 and ... It inhibits DNA metabolism and is used as an antineoplastic, especially for solid tumors. …
Matched Salts name: … Bleomycin sulfate
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Cytotoxic Antibiotics and Related Substances …
Matched Products: … BIXEL (BLEOMYCIN SULPHATE FOR INJECTION 15 UNITS) ... DBL™ BLEOMYCIN SULFATE FOR INJECTION 15 units ... DBL BLEOMYCIN SULFATE FOR INJECTION 15000 iu/vial …
Approved
Matched Synonyms: … Thallium (201Tl) chloride ... Thallous chloride Tl 201 …
Matched Name: … Thallous chloride Tl-201 …
Matched Categories: … thallium (201Tl) chloride
Matched Products: … Thallous Chloride Tl 201 ... THALLOUS CHLORIDE Tl 201 …
Experimental
Matched Name: … Ferrous tartrate
Matched Categories: … Blood and Blood Forming Organs ... ferrous tartrate
Experimental
Matched Synonyms: … Acetic chloride ... Ethanoyl chloride ... Acetic acid chloride
Matched Name: … Acetyl chloride
Matched Iupac: … acetyl chloride
Matched Categories: … Chlorine Compounds …
Labetuzumab is a humanized monoclonal antibody to carcinoembryonic antigen that inhibits tumor growth. It is used in radioimmunotherapy.
Investigational
Matched Synonyms: … Monoclonal antibody hMN-14 ... MN14 monoclonal antibody to carcinoembryonic antigen …
Matched Description: … Labetuzumab is a humanized monoclonal antibody to carcinoembryonic antigen that inhibits tumor growth …
Matched Categories: … Amino Acids, Peptides, and Proteins …
An anionic surface-active agent used for its wetting properties in industry and used in medicine as an irritant and sclerosing agent for hemorrhoids and varicose veins.
Approved
Investigational
Matched Synonyms: … Natrii tetradecylis sulfa ... Sodium tetradecyl sulfate ... Tetradecyl sodium sulfate
Matched Name: … Sodium tetradecyl sulfate
Matched Iupac: … sodium 7-ethyl-2-methylundecan-4-yl sulfate
Matched Description: … irritant and sclerosing agent for hemorrhoids and varicose veins. ... An anionic surface-active agent used for its wetting properties in industry and used in medicine as an …
Matched Categories: … sodium tetradecyl sulfate
Matched Products: … Sodium Tetradecyl Sulfate
Lanthanum carbonate is a phosphate binder marketed under the trade name Fosrenol by Shire Pharmaceuticals. It is a large pill that requires thorough chewing to avoid choking and other gastrointestinal adverse effects. It is used to treat elevated phosphate levels, primarily in patients with chronic kidney disease, by binding to...
Approved
Matched Synonyms: … Lanthanum (III) carbonate ... Lanthanum(3+) carbonate ... Lanthanum carbonate anhydrous …
Matched Name: … Lanthanum carbonate
Matched Description: … binding to dietary phosphate and preventing its absorption in the intestine. ... Lanthanum carbonate is a phosphate binder marketed under the trade name _Fosrenol_ by Shire Pharmaceuticals ... It is a large pill that requires thorough chewing to avoid choking and other gastrointestinal adverse …
Matched Salts name: … Lanthanum carbonate hydrate …
Matched Categories: … Drugs for Treatment of Hyperkalemia and Hyperphosphatemia ... lanthanum carbonate ... Phosphate Binder ... Phosphate-removing Agents …
Matched Products: … Lanthanum Carbonate ... Lanthanum carbonate
An aminoquinoline that is given by mouth to produce a radical cure and prevent relapse of vivax and ovale malarias following treatment with a blood schizontocide. It has also been used to prevent transmission of falciparum malaria by those returning to areas where there is a potential for re-introduction of...
Approved
Matched Description: … An aminoquinoline that is given by mouth to produce a radical cure and prevent relapse of vivax and ovale ... Adverse effects include anemias and GI disturbances. …
Matched Salts name: … Primaquine phosphate
Matched Categories: … Antiparasitic Products, Insecticides and Repellents …
Matched Products: … Primaquine Phosphate ... PRIMAQUINE PHOSPHATE
Varenicline is a prescription medication used to treat smoking addiction. This medication is the first approved nicotinic receptor partial agonist. Specifically, varenicline is a partial agonist of the alpha4/beta2 subtype of the nicotinic acetylcholine receptor. In addition it acts on alpha3/beta4 and weakly on alpha3beta2 and alpha6-containing receptors. A full...
Approved
Investigational
Matched Description: … In addition it acts on alpha3/beta4 and weakly on alpha3beta2 and alpha6-containing receptors. ... Food and Drug Administration warned that Varenicline, in the form of Pfizer Inc's quit-smoking drug, ... Chantix, has been associated with seizures and that some patients who drink while taking the drug may …
Matched Mixtures name: … Varenicline tartrate ... Varenicline tartrate ... Varenicline Tartrate
Matched Salts name: … Varenicline tartrate
Matched Products: … Varenicline tartrate ... Varenicline Tartrate
Idursulfase beta is under investigation in clinical trial NCT01645189 (Safety and Efficacy of Hunterase).
Investigational
Matched Synonyms: … Iduronate 2-sulfatase (a-l-iduronate sulfate sulfatase), human proenzyme produced in cho cells (glycoform …
Matched Description: … Idursulfase beta is under investigation in clinical trial NCT01645189 (Safety and Efficacy of Hunterase …
Matched Categories: … Alimentary Tract and Metabolism ... Enzymes and Coenzymes …
Methylene blue is an oxidation-reduction agent. The intravenous form of methylene blue is approved by the FDA for the treatment of pediatric and adult patients with acquired methemoglobinemia. Historically, it has been widely used in Africa to treat malaria, but now it disappeared when chloroquine (CQ) and other drugs entered...
Approved
Investigational
Matched Synonyms: … Chlorure de méthylthioninium ... Methylthioninii chloridum ... Methylthioninium chloride
Matched Iupac: … 3,7-bis(dimethylamino)-5λ⁴-phenothiazin-5-ylium chloride
Matched Description: … The intravenous form of methylene blue is approved by the FDA for the treatment of pediatric and adult ... Historically, it has been widely used in Africa to treat malaria, but now it disappeared when chloroquine (CQ) and ... drug being developed by the University of Aberdeen and TauRx Therapeutics that has been shown in early …
Matched Categories: … methylthioninium chloride ... methylthioninium chloride
Matched Products: … Methylthioninium Chloride Cosmo ... Methylthioninium Chloride Proveblue …
Indium In-111 Chloride is a diagnostic radiopharmaceutical agent intended for radiolabeling OncoScint (satumomab pendetide) or ProstaScint (capromab pendetide) used for in vivo diagnostic imaging procedures and for radiolabeling Zevalin (ibritumomab tiuxetan) in preparations used for radioimmunotherapy procedures. It is supplied as a sterile, pyrogen-free solution of Indium ("'In) Chloride in...
Approved
Matched Synonyms: … Indium-111 chloride ... Indium (111In) chloride ... Indium chloride In-111 …
Matched Name: … Indium In-111 chloride
Matched Description: … satumomab pendetide) or ProstaScint (capromab pendetide) used for _in vivo_ diagnostic imaging procedures and ... Indium In-111 Chloride is a diagnostic radiopharmaceutical agent intended for radiolabeling OncoScint ... It is supplied as a sterile, pyrogen-free solution of Indium ("'In) Chloride in O.04M HCI. …
Matched Products: … Indium In 111 Chloride ... INDIUM (In111) CHLORIDE INJECTION 370 MBq/ml …
Experimental
Matched Synonyms: … p-Nitrocatechol sulfate ... para-Nitrocatechol sulfate ... 2-Hydroxy-5-nitrophenyl sulfate
Matched Name: … 4-Nitrocatechol sulfate
Galiximab is a chimeric monoclonal antibody which is used as an immunosuppressive drug.
Investigational
Matched Synonyms: … Anti-CD80 monoclonal antibody
Matched Description: … Galiximab is a chimeric monoclonal antibody which is used as an immunosuppressive drug. …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Farletuzumab ecteribulin is under investigation in clinical trial NCT04300556 (A Study to Evaluate the Safety, Tolerability, and Efficacy of Morab-202 (Herein Referred to as Farletuzumab Ecteribulin), a Folate Receptor Alpha (Frα)-targeting Antibody-drug Conjugate (ADC) in Participants With Selected Tumor Types).
Investigational
Matched Synonyms: … Eribulin/farletuzumab antibody drug conjugate …
Matched Description: … is under investigation in clinical trial NCT04300556 (A Study to Evaluate the Safety, Tolerability, and ... Morab-202 (Herein Referred to as Farletuzumab Ecteribulin), a Folate Receptor Alpha (Frα)-targeting Antibody-drug …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antibody-drug Conjugates …
The humanized anti-IL-12 antibody is an important addition to PDL's already strong pipeline of humanized antibodies being developed for the treatment of autoimmune diseases. SMART Anti-IL-12 Antibody was humanized at PDL from a murine anti-IL-12 antibody that was licensed, together with certain intellectual property related to anti-IL-12 therapy, from Hoffmann-La...
Investigational
Matched Name: … humanized SMART Anti-IL-12 Antibody
Matched Description: … SMART Anti-IL-12 Antibody was humanized at PDL from a murine anti-IL-12 antibody that was licensed, together ... The humanized anti-IL-12 antibody is an important addition to PDL's already strong pipeline of humanized …
Oregovomab is a murine monoclonal antibody that attaches to the tumor-associated antigen CA125.
Investigational
Matched Synonyms: … Monoclonal antibody B43.13 …
Matched Description: … Oregovomab is a murine monoclonal antibody that attaches to the tumor-associated antigen CA125. …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Approved
Experimental
Matched Synonyms: … Monoclonal antibody anti-SSEA-1 …
Matched Categories: … Amino Acids, Peptides, and Proteins …
EMB-01 is under investigation in clinical trial NCT03797391 (A Dose Escalation Study of EMB-01 in Participants With Advanced/metastatic Solid Tumors).
Investigational
Matched Synonyms: … Anti-egfr/c-met bispecific antibody emb-01 ... Anti-egfr/anti-c-met bispecific antibody emb-01 …
Quinidine is a D-isomer of quinine present in the bark of the Cinchona tree and similar plant species. This alkaloid was first described in 1848 and has a long history as an antiarrhythmic medication.[A38016,A250050] Quinidine is considered the first antiarrhythmic drug (class Ia) and is moderately efficacious in the acute...
Approved
Investigational
Matched Description: … [A38016] It prolongs cellular action potential by blocking sodium and potassium currents. ... Quinidine is a D-isomer of [quinine] present in the bark of the Cinchona tree and similar plant species ... This alkaloid was first described in 1848 and has a long history as an antiarrhythmic medication. …
Matched Salts name: … Quinidine sulfate
Matched Categories: … Quinine and stereoisomer ... Metabolic Side Effects of Drugs and Substances …
Matched Products: … Quinidine Sulfate ... Quinidine Sulfate 200mg ... Quinidine Sulfate Tab 200mg …
Approved
Experimental
Matched Synonyms: … Foeniculum vulgare top …
Displaying drugs 501 - 525 of 1173 in total