Displaying drugs 501 - 525 of 2456 in total
Eftrenonacog alfa
Eftrenonacog alfa is a long-acting recombinant fusion protein used in the treatment of hemophilia B. It is comprised of a single molecule of human factor IX (FIX) covalently linked to the constant region (Fc) domain of human IgG1 via recombinant DNA technology in a human embryonic kidney cell line (HEK293H)...
Approved
Investigational
Matched Synonyms: … Eftrenonacog alfa …
Matched Name: … Eftrenonacog alfa …
Matched Description: … Eftrenonacog alfa was developed and marketed as Alprolix for intravenous injection by Biogen. ... Eftrenonacog alfa acts as a replacement therapy to restore the levels of factor IX and allow normal hemostasis ... It was first approved by the FDA in March 2014 and later approved by the EMA in May 2016. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Enzymes and Coenzymes …
Matched Name: … Eftrenonacog alfa …
Matched Description: … Eftrenonacog alfa was developed and marketed as Alprolix for intravenous injection by Biogen. ... Eftrenonacog alfa acts as a replacement therapy to restore the levels of factor IX and allow normal hemostasis ... It was first approved by the FDA in March 2014 and later approved by the EMA in May 2016. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Enzymes and Coenzymes …
Eptotermin alfa
A bone morphogenetic protein that is widely expressed during EMBRYONIC DEVELOPMENT. It is both a potent osteogenic factor and a specific regulator of nephrogenesis. Eptotermin alfa is an ingredient in the EMA-withdrawn product Osigraft.
Approved
Investigational
Withdrawn
Matched Synonyms: … Eptotermin alfa ... Eptotermina alfa …
Matched Name: … Eptotermin alfa …
Matched Description: … It is both a potent osteogenic factor and a specific regulator of nephrogenesis. ... Eptotermin alfa is an ingredient in the EMA-withdrawn product Osigraft. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... eptotermin alfa ... Drugs Affecting Bone Structure and Mineralization ... Intercellular Signaling Peptides and Proteins …
Matched Name: … Eptotermin alfa …
Matched Description: … It is both a potent osteogenic factor and a specific regulator of nephrogenesis. ... Eptotermin alfa is an ingredient in the EMA-withdrawn product Osigraft. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... eptotermin alfa ... Drugs Affecting Bone Structure and Mineralization ... Intercellular Signaling Peptides and Proteins …
Dibotermin alfa
Dibotermin alfa is a recombinant human bone morphogenetic protein-2 (rhBMP-2) derived from a recombinant Chinese Hamster Ovary (CHO) cell line [FDA Label]. It is implanted in patients undergoing bone surgeries or those with fractures. BMPs are subfamily of the transforming growth factor-β (TGF-β) superfamily that have different actions on the...
Approved
Investigational
Matched Synonyms: … Dibotermin alfa ... Dibotermina alfa …
Matched Name: … Dibotermin alfa …
Matched Description: … 131 amino acids. ... In 2004, it was approved by the FDA and is marketed as Infuse. ... open tibial shaft fractures and reduces the need for secondary intervention [A31945]. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... dibotermin alfa ... Drugs Affecting Bone Structure and Mineralization ... Intercellular Signaling Peptides and Proteins …
Matched Name: … Dibotermin alfa …
Matched Description: … 131 amino acids. ... In 2004, it was approved by the FDA and is marketed as Infuse. ... open tibial shaft fractures and reduces the need for secondary intervention [A31945]. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... dibotermin alfa ... Drugs Affecting Bone Structure and Mineralization ... Intercellular Signaling Peptides and Proteins …
Cerliponase alfa
Cerliponase alfa is an enzyme replacement treatment for a specific form of Batten disease. It was the first FDA-approved treatment to slow loss of walking ability (ambulation) in symptomatic pediatric patients 3 years of age and older with late infantile neuronal ceroid lipofuscinosis type 2 (CLN2), also known as tripeptidyl...
Approved
Investigational
Matched Synonyms: … Cerliponase alfa …
Matched Name: … Cerliponase alfa …
Matched Description: … treatment to slow loss of walking ability (ambulation) in symptomatic pediatric patients 3 years of age and ... Cerliponase alfa was approved in April, 2017 (as Brineura). ... Cerliponase alfa is an enzyme replacement treatment for a specific form of Batten disease. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... cerliponase alfa ... Enzymes and Coenzymes ... Alimentary Tract and Metabolism …
Matched Name: … Cerliponase alfa …
Matched Description: … treatment to slow loss of walking ability (ambulation) in symptomatic pediatric patients 3 years of age and ... Cerliponase alfa was approved in April, 2017 (as Brineura). ... Cerliponase alfa is an enzyme replacement treatment for a specific form of Batten disease. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... cerliponase alfa ... Enzymes and Coenzymes ... Alimentary Tract and Metabolism …
Andexanet alfa
Andexanet alfa is a recombinant human coagulation Factor Xa that promotes blood coagulation. It was developed by Portola Pharmaceuticals and was approved in in May 2018. It is marketed as Andexxa for intravenous injection or infusion and is indicated for the reversal of anticoagulation in combination with rivaroxaban and apixaban...
Approved
Investigational
Matched Synonyms: … Andexanet alfa …
Matched Name: … Andexanet alfa …
Matched Description: … Andexanet alfa is currently under regulatory review by the European Union and is undergoing clinical ... Andexanet alfa works by binding to Factor Xa inhibitors and prevent them from interacting with endogenous ... containing Gla: via this truncation, andexanet alfa is unable to bind to membrane surfaces and assemble …
Matched Categories: … Amino Acids, Peptides, and Proteins ... andexanet alfa ... Enzymes and Coenzymes …
Matched Name: … Andexanet alfa …
Matched Description: … Andexanet alfa is currently under regulatory review by the European Union and is undergoing clinical ... Andexanet alfa works by binding to Factor Xa inhibitors and prevent them from interacting with endogenous ... containing Gla: via this truncation, andexanet alfa is unable to bind to membrane surfaces and assemble …
Matched Categories: … Amino Acids, Peptides, and Proteins ... andexanet alfa ... Enzymes and Coenzymes …
Simlukafusp alfa
RO6874281 is under investigation in clinical trial NCT03193190 (A Study of Multiple Immunotherapy-based Treatment Combinations in Participants With Metastatic Pancreatic Ductal Adenocarcinoma (Morpheus-pancreatic Cancer)).
Investigational
Matched Name: … Simlukafusp alfa …
Efavaleukin alfa
Efavaleukin alfa is a fusion protein consisting of interleukin mutein fused to the C-terminus of an immunoglobulin G Fc domain by way of a G4S linker. It is under investigation in clinical trial NCT03422627 (Safety and Efficacy of AMG 592 in Subjects With Steroid Refractory Chronic Graft Versus Host Disease).
Investigational
Matched Synonyms: … Efavaleukin alfa …
Matched Name: … Efavaleukin alfa …
Matched Description: … It is under investigation in clinical trial NCT03422627 (Safety and Efficacy of AMG 592 in Subjects With ... Efavaleukin alfa is a fusion protein consisting of interleukin mutein fused to the C-terminus of an immunoglobulin …
Matched Name: … Efavaleukin alfa …
Matched Description: … It is under investigation in clinical trial NCT03422627 (Safety and Efficacy of AMG 592 in Subjects With ... Efavaleukin alfa is a fusion protein consisting of interleukin mutein fused to the C-terminus of an immunoglobulin …
Talditercept alfa
Talditercept alfa is under investigation in clinical trial NCT03039686 (Clinical Trial to Evaluate the Efficacy, Safety, and Tolerability of RO7239361 in Ambulatory Boys With Duchenne Muscular Dystrophy).
Investigational
Matched Synonyms: … Taldefgrobep alfa ... Talditercept alfa ... Immunoglobulin g1 (human fc fragment) fusion protein with peptide (synthetic 17-amino acid linker) fusion …
Matched Name: … Talditercept alfa …
Matched Description: … Efficacy, Safety, and Tolerability of RO7239361 in Ambulatory Boys With Duchenne Muscular Dystrophy) ... Talditercept alfa is under investigation in clinical trial NCT03039686 (Clinical Trial to Evaluate the …
Matched Name: … Talditercept alfa …
Matched Description: … Efficacy, Safety, and Tolerability of RO7239361 in Ambulatory Boys With Duchenne Muscular Dystrophy) ... Talditercept alfa is under investigation in clinical trial NCT03039686 (Clinical Trial to Evaluate the …
Eflepedocokin alfa
Eflepedocokin alfa is a recombinant IL-22-Fc fusion protein manufactured in Chinese hamster ovary cells that is composed of 2 human interleukin 22 (IL-22) molecules linked to an immunoglobulin constant region (IgG2-Fc).[A225706, L27661] It is being developed by Evive Biotech (previously known as Generon BioMed Inc).
Investigational
Matched Name: … Eflepedocokin alfa …
Matched Description: … Eflepedocokin alfa is a recombinant IL-22-Fc fusion protein manufactured in Chinese hamster ovary cells …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins …
Matched Description: … Eflepedocokin alfa is a recombinant IL-22-Fc fusion protein manufactured in Chinese hamster ovary cells …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins …
Bucelipase alfa
Bucelipase alfa is under investigation in clinical trial NCT00743483 (Efficacy of Bucelipase Alfa (BSSL) in Patients With Cystic Fibrosis and Pancreatic Insufficiency).
Investigational
Matched Name: … Bucelipase alfa …
Matched Description: … ) in Patients With Cystic Fibrosis and Pancreatic Insufficiency). ... Bucelipase alfa is under investigation in clinical trial NCT00743483 (Efficacy of Bucelipase Alfa (BSSL …
Matched Description: … ) in Patients With Cystic Fibrosis and Pancreatic Insufficiency). ... Bucelipase alfa is under investigation in clinical trial NCT00743483 (Efficacy of Bucelipase Alfa (BSSL …
Tralesinidase alfa
Tralesinidase alfa is a chimeric fusion protein comprised of recombinant human NAGLU and a modified human insulin-like growth factor 2. It is being investigated for the treatment of mucopolysaccharidosis type IIIB (MPS IIIB), also known as Sanfilippo syndrome B.
Investigational
Matched Synonyms: … Tralesinidase alfa …
Matched Name: … Tralesinidase alfa …
Matched Description: … Tralesinidase alfa is a chimeric fusion protein comprised of recombinant human NAGLU and a modified human …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Enzymes and Coenzymes ... Intercellular Signaling Peptides and Proteins …
Matched Name: … Tralesinidase alfa …
Matched Description: … Tralesinidase alfa is a chimeric fusion protein comprised of recombinant human NAGLU and a modified human …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Enzymes and Coenzymes ... Intercellular Signaling Peptides and Proteins …
Eftansomatropin alfa
Eftansomatropin alfa (GX-H9) comprises a recombinant human growth hormone fused to hyFc, a synthetic hybrid Fc fragment. It is under investigation for the treatment of growth hormone deficiency.
Investigational
Matched Synonyms: … Eftansomatropin alfa …
Matched Name: … Eftansomatropin alfa …
Matched Description: … Eftansomatropin alfa (GX-H9) comprises a recombinant human growth hormone fused to hyFc, a synthetic …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Name: … Eftansomatropin alfa …
Matched Description: … Eftansomatropin alfa (GX-H9) comprises a recombinant human growth hormone fused to hyFc, a synthetic …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Lusacomfar Alfa
Lusacomfar Alfa is a recombinant complement factor H
Investigational
Matched Name: … Lusacomfar Alfa …
Matched Description: … Lusacomfar Alfa is a recombinant complement factor H …
Matched Description: … Lusacomfar Alfa is a recombinant complement factor H …
Zelpultide alfa
Zelpultide alfa is a recombinant human surfactant protein D.
Investigational
Matched Synonyms: … PROTEIN D), NON-COVALENT QUADRUPLE TRIMER, PRODUCED IN HUMAN MYELOGENOUS LEUKEMIA K562 CELLS, GLYCOFORME ALFA …
Matched Name: … Zelpultide alfa …
Matched Description: … Zelpultide alfa is a recombinant human surfactant protein D. …
Matched Name: … Zelpultide alfa …
Matched Description: … Zelpultide alfa is a recombinant human surfactant protein D. …
Efbemalenograstim alfa
Efbemalenograstim alfa is a long-acting recombinant fusion protein of granulocyte-colony stimulating factor (G-CSF) due to the addition of the Fc portion of human IgG2, allowing for once-per-cycle administration.[L48852,A262167] As endogenous G-CSF mediates the differentiation of hematopoietic stem cells into granulocytes and eventually neutrophils, the administration of recombinant G-CSF like efbemalenograstim...
Approved
Matched Name: … Efbemalenograstim alfa …
Matched Description: … the production of neutrophils and thus reducing the severity and duration of neutropenia. ... GC-627-05 in the US and Europe respectively. ... A262167] As endogenous G-CSF mediates the differentiation of hematopoietic stem cells into granulocytes and …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... efbemalenograstim alfa …
Matched Description: … the production of neutrophils and thus reducing the severity and duration of neutropenia. ... GC-627-05 in the US and Europe respectively. ... A262167] As endogenous G-CSF mediates the differentiation of hematopoietic stem cells into granulocytes and …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... efbemalenograstim alfa …
Interferon alfa-2b
Interferon alpha 2b (human leukocyte clone hif-sn 206 protein moiety reduced). A type I interferon consisting of 165 amino acid residues with arginine in position 23. This protein is produced by recombinant DNA technology and resembles interferon secreted by leukocytes. It is used extensively as an antiviral or antineoplastic agent.
Approved
Matched Synonyms: … Interferon alfa-2b ... Interferon alfa-2b (recombinant) ... Interferon alfa-2b, recombinant …
Matched Name: … Interferon alfa-2b …
Matched Description: … This protein is produced by recombinant DNA technology and resembles interferon secreted by leukocytes ... A type I interferon consisting of 165 amino acid residues with arginine in position 23. …
Matched Mixtures name: … Rebetron Ready To Use Solution (albumin(human)free) (6000000 Iu/ml and 200mg Capsules) …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Alfa Interferons ... Antineoplastic and Immunomodulating Agents ... interferon alfa-2b ... Intercellular Signaling Peptides and Proteins …
Matched Name: … Interferon alfa-2b …
Matched Description: … This protein is produced by recombinant DNA technology and resembles interferon secreted by leukocytes ... A type I interferon consisting of 165 amino acid residues with arginine in position 23. …
Matched Mixtures name: … Rebetron Ready To Use Solution (albumin(human)free) (6000000 Iu/ml and 200mg Capsules) …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Alfa Interferons ... Antineoplastic and Immunomodulating Agents ... interferon alfa-2b ... Intercellular Signaling Peptides and Proteins …
Pipemidic acid
Experimental
Matched Synonyms: … Pipemidic acid ... acido pipemidico …
Matched Name: … Pipemidic acid …
Matched Iupac: … 8-ethyl-5-oxo-2-(piperazin-1-yl)-5H,8H-pyrido[2,3-d]pyrimidine-6-carboxylic acid …
Matched Salts name: … Pipemidic acid trihydrate …
Matched Categories: … Acids, Heterocyclic ... pipemidic acid ... Nicotinic Acids …
Matched Products: … ACIDO PIPEMIDICO EG ... ACIDO PIPEMIDICO AUROBINDO ... ACIDO PIPEMIDICO DR. REDDY'S …
Matched Name: … Pipemidic acid …
Matched Iupac: … 8-ethyl-5-oxo-2-(piperazin-1-yl)-5H,8H-pyrido[2,3-d]pyrimidine-6-carboxylic acid …
Matched Salts name: … Pipemidic acid trihydrate …
Matched Categories: … Acids, Heterocyclic ... pipemidic acid ... Nicotinic Acids …
Matched Products: … ACIDO PIPEMIDICO EG ... ACIDO PIPEMIDICO AUROBINDO ... ACIDO PIPEMIDICO DR. REDDY'S …
Orotic acid
Investigational
Matched Synonyms: … Orotic acid ... Acido orotico ... Acidum oroticum …
Matched Name: … Orotic acid …
Matched Iupac: … 2,6-dioxo-1,2,3,6-tetrahydropyrimidine-4-carboxylic acid …
Matched Categories: … Acids, Heterocyclic …
Matched Name: … Orotic acid …
Matched Iupac: … 2,6-dioxo-1,2,3,6-tetrahydropyrimidine-4-carboxylic acid …
Matched Categories: … Acids, Heterocyclic …
Telitacicept
Investigational
Matched Synonyms: … (L120>A,L121>E,G123>A,A216>S,P217>S)-TACI (TRANSMEMBRANE ACTIVATOR AND CAML INTERACTOR, TUMOR NECROSIS …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Nalidixic acid
Nalidixic acid is a synthetic 1,8-naphthyridine antimicrobial agent with a limited bacteriocidal spectrum. It is an inhibitor of the A subunit of bacterial DNA gyrase.
Approved
Investigational
Matched International brands: … Nal-acid …
Matched Synonyms: … Nalidixic acid ... Acido nalidixico ... Acide nalidixique …
Matched Name: … Nalidixic acid …
Matched Iupac: … 1-ethyl-7-methyl-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid …
Matched Description: … Nalidixic acid is a synthetic 1,8-naphthyridine antimicrobial agent with a limited bacteriocidal spectrum …
Matched Categories: … nalidixic acid …
Matched Products: … ACIDO NALIDIXICO ... ACIDO NALIDIXICO NOVASOREL ... ACIDO NALIDIXICO SUSPENSION …
Matched Synonyms: … Nalidixic acid ... Acido nalidixico ... Acide nalidixique …
Matched Name: … Nalidixic acid …
Matched Iupac: … 1-ethyl-7-methyl-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid …
Matched Description: … Nalidixic acid is a synthetic 1,8-naphthyridine antimicrobial agent with a limited bacteriocidal spectrum …
Matched Categories: … nalidixic acid …
Matched Products: … ACIDO NALIDIXICO ... ACIDO NALIDIXICO NOVASOREL ... ACIDO NALIDIXICO SUSPENSION …
Diatrizoate
A commonly used x-ray contrast medium. As diatrizoate meglumine and as Diatrizoate sodium, it is used for gastrointestinal studies, angiography, and urography.
Approved
Vet approved
Matched Synonyms: … Urografin acid ... Diatrizoic acid ... Methalamic acid …
Matched Iupac: … 3,5-diacetamido-2,4,6-triiodobenzoic acid …
Matched Description: … , and urography. ... As diatrizoate meglumine and as Diatrizoate sodium, it is used for gastrointestinal studies, angiography …
Matched Mixtures name: … Diatrizoate Meglumine and Diatrizoate Sodium ... Diatrizoate Meglumine and Diatrizoate Sodium ... Diatrizoate Meglumine and Diatrizoate Sodium …
Matched Salts name: … Diatrizoic acid dihydrate …
Matched Categories: … Acids, Carbocyclic ... Carboxylic Acids ... diatrizoic acid ... Triiodobenzoic Acids …
Matched Iupac: … 3,5-diacetamido-2,4,6-triiodobenzoic acid …
Matched Description: … , and urography. ... As diatrizoate meglumine and as Diatrizoate sodium, it is used for gastrointestinal studies, angiography …
Matched Mixtures name: … Diatrizoate Meglumine and Diatrizoate Sodium ... Diatrizoate Meglumine and Diatrizoate Sodium ... Diatrizoate Meglumine and Diatrizoate Sodium …
Matched Salts name: … Diatrizoic acid dihydrate …
Matched Categories: … Acids, Carbocyclic ... Carboxylic Acids ... diatrizoic acid ... Triiodobenzoic Acids …
Cromoglicic acid
A chromone complex that acts by inhibiting the release of chemical mediators from sensitized mast cells. It is used in the prophylactic treatment of both allergic and exercise-induced asthma, but does not affect an established asthmatic attack.
Approved
Matched Synonyms: … Cromoglicic acid ... Cromoglycic acid ... Acido Cromoglicico …
Matched Name: … Cromoglicic acid …
Matched Iupac: … 5-{3-[(2-carboxy-4-oxo-4H-chromen-5-yl)oxy]-2-hydroxypropoxy}-4-oxo-4H-chromene-2-carboxylic acid …
Matched Description: … It is used in the prophylactic treatment of both allergic and exercise-induced asthma, but does not affect …
Matched Categories: … Alimentary Tract and Metabolism ... Decongestants and Antiallergics ... reproterol and sodium cromoglicate ... salbutamol and sodium cromoglicate ... cromoglicic acid …
Matched Name: … Cromoglicic acid …
Matched Iupac: … 5-{3-[(2-carboxy-4-oxo-4H-chromen-5-yl)oxy]-2-hydroxypropoxy}-4-oxo-4H-chromene-2-carboxylic acid …
Matched Description: … It is used in the prophylactic treatment of both allergic and exercise-induced asthma, but does not affect …
Matched Categories: … Alimentary Tract and Metabolism ... Decongestants and Antiallergics ... reproterol and sodium cromoglicate ... salbutamol and sodium cromoglicate ... cromoglicic acid …
Naphazoline
Naphazoline is a rapid acting imidazoline sympathomimetic vasoconstrictor of ocular or nasal artierioles[L5804,L5807]. It acts to decrease congestion and is found in many over the counter (OTC) eye drops and nasal preparations[L5804,L5807].
Naphazoline was first developed in 1942 as a nasal formulation for congestion .
Approved
Investigational
Matched Description: … It acts to decrease congestion and is found in many over the counter (OTC) eye drops and nasal preparations …
Matched Mixtures name: … COLLIRIO ALFA ANTISTAMINICO ... COLLIRIO ALFA ANTISTAMINICO ... Lubricant and Redness Reliever …
Matched Categories: … Decongestants and Antiallergics …
Matched Products: … COLLIRIO ALFA DECONGESTIONANTE …
Matched Mixtures name: … COLLIRIO ALFA ANTISTAMINICO ... COLLIRIO ALFA ANTISTAMINICO ... Lubricant and Redness Reliever …
Matched Categories: … Decongestants and Antiallergics …
Matched Products: … COLLIRIO ALFA DECONGESTIONANTE …
Displaying drugs 501 - 525 of 2456 in total