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Displaying drugs 501 - 525 of 11857 in total
Approved
Matched Categories: … Compounds used in a research, industrial, or household setting …
Nonacog beta pegol is a recombinant coagulation factor IX derivative. It is produced without animal-derived materials and with an attached 40kDa polyethylene glycol (PEG) molecule for peptide activation by a site-directed glycoPEGylation. Once activated, the activation molecule with PEG is cleaved to leave the activated factor IX (Factor IXa). Nonacog...
Approved
Investigational
Matched Categories: … Compounds used in a research, industrial, or household setting …
Gadoversetamide, marketed under the trade name OptiMARK, is a gadolinium compound used as a contrast agent in magnetic resonance imaging (MRI), particularly imaging of the brain, spine and liver.
Approved
Investigational
Matched Description: … Gadoversetamide, marketed under the trade name OptiMARK, is a gadolinium compound used as a contrast agent in
Matched Categories: … Compounds used in a research, industrial, or household setting …
Colletotrichum coccodes is a fungus which can provoke allergic reactions. Colletotrichum coccodes extract is used in allergenic testing.
Approved
Matched Description: … Colletotrichum coccodes extract is used in allergenic testing. …
Approved
Vet approved
Withdrawn
Cyproheptadine is a potent competitive antagonist of both serotonin and histamine receptors. It is used primarily to treat allergic symptoms, though it is perhaps more notable for its use in appetite stimulation and its off-label use in the treatment of serotonin syndrome.
Approved
Matched Description: … appetite stimulation[L32519] and its off-label use in the treatment of serotonin syndrome. ... L32474] It is used primarily to treat allergic symptoms, though it is perhaps more notable for its use in
Calcium glubionate (or glubionate calcium) is a mineral supplement to prevent or treat low blood calcium levels in people who do not get enough calcium from their diets.
Approved
Matched Description: … glubionate (or glubionate calcium) is a mineral supplement to prevent or treat low blood calcium levels in
Amikacin is a semi-synthetic aminoglycoside antibiotic that is derived from kanamycin A.[FDA label] Amikacin is synthesized by acylation with the l-(-)-γ-amino-α-hydroxybutyryl side chain at the C-1 amino group of the deoxystreptamine moiety of kanamycin A. Amikacin's unique property is that it exerts activity against more resistant gram-negative bacilli such as...
Approved
Investigational
Vet approved
Matched Description: … label] Amikacin is synthesized by acylation with the l-(-)-γ-amino-α-hydroxybutyryl side chain at the C- ... M. avium-intracellulare (MAC) is a type of nontuberculous mycobacteria (NTM) found in water and soil. ... [F1949] In September 2018, a liposomal inhalation suspension of this drug was approved by the FDA for …
Vardenafil is a selective inhibitor of cyclic guanosine monophosphate (cGMP)-specific phosphodiesterase type 5 (PDE5) and an oral therapy for the treatment of erectile dysfunction.[L45563,L45568] During sexual stimulation, nitric oxide (NO) is released from nerve endings and endothelial cells in the corpus cavernosum, activating the enzyme guanylate cyclase and increasing the...
Approved
Matched Description: … ] During sexual stimulation, nitric oxide (NO) is released from nerve endings and endothelial cells in ... the corpus cavernosum, activating the enzyme guanylate cyclase and increasing the synthesis of cGMP in ... vardenafil, inhibit the degradation of cGMP and allow increased blood flow into the penis, resulting in
Matched Categories: … Drugs Used in Erectile Dysfunction …
SARS-CoV-2, the causative agent of COVID-19, enters cells via the interaction between the trimeric spike (S) glycoprotein and host cell angiotensin-converting enzyme 2 (ACE2). Blocking the interaction between the receptor-binding domain (RBD) of the S1 subunit and ACE2 inhibits viral host cell entry; animal studies indicate that antibodies capable of...
Approved
Investigational
Matched Description: … Cilgavimab, in combination with [tixagevimab], was issued an FDA emergency use authorization (EUA) on ... December 9, 2021, for the pre-exposure prophylaxis of COVID-19 in individuals at increased risk for ... [A243356, A243361] Cilgavimab (formerly AZD1061) is a recombinant monoclonal antibody produced in Chinese …
SARS-CoV-2, the causative agent of COVID-19, enters cells via the interaction between the trimeric spike (S) glycoprotein and host cell angiotensin-converting enzyme 2 (ACE2). Blocking the interaction between the receptor-binding domain (RBD) of the S1 subunit and ACE2 inhibits viral host cell entry; animal studies indicate that antibodies capable of...
Approved
Investigational
Matched Description: … Tixagevimab, in combination with [cilgavimab], was issued an FDA emergency use authorization (EUA) on ... December 9, 2021, for the pre-exposure prophylaxis of COVID-19 in individuals at increased risk for ... [L41549] In October 2022, the FDA and Health Canada released safety alerts regarding the risk of …
Cardioactive derivative of lanatoside A or of digitoxin used for fast digitalization in congestive heart failure.
Approved
Matched Description: … Cardioactive derivative of lanatoside A or of digitoxin used for fast digitalization in congestive heart …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Aluminum chloride is a chemical compound with the chemical formula AlCl3. When contaminated with iron chloride, it often displays a yellow color compared to the white pure compound. It is used in various chemical applications as a Lewis base, with anhydrous aluminium trichloride being the most commonly used Lewis acid....
Approved
Investigational
Matched Description: … , calculated on the hexahydrate form, in an aqueous solution nonaerosol dosage form [L2012]. ... It is used in various chemical applications as a Lewis base, with anhydrous aluminium trichloride being ... In antiperspirant products, FDA approves the use of aluminum chloride as an active ingredient up to 15% …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Calcipotriol (INN) or calcipotriene (USAN) is a sythetic derivative of calcitriol or Vitamin D.
Approved
An amino acid derivative that occurs in vertebrate tissues and in urine. In muscle tissue, creatine generally occurs as phosphocreatine. Creatine is excreted as creatinine in the urine.
Approved
Investigational
Nutraceutical
Matched Description: … An amino acid derivative that occurs in vertebrate tissues and in urine. ... Creatine is excreted as creatinine in the urine. ... In muscle tissue, creatine generally occurs as phosphocreatine. …
Chickpea allergenic extract is used in allergenic testing.
Approved
Matched Description: … Chickpea allergenic extract is used in allergenic testing. …
Approved
Clobazam belongs to the 1,5-benzodiazepine class of drugs and is marketed under different names, Onfi, Frisium, Urbanyl, and others. . Clobazam was first synthesized in 1966 and first published in 1969, following the incidental synthesis and discovery of the first benzodiazepine chlordiazepoxide in the 1950s. Unlike older 1,4-benzodiazepines, clobazam has...
Approved
Illicit
Matched Description: … Clobazam was first synthesized in 1966 and first published in 1969, following the incidental synthesis ... and discovery of the first benzodiazepine chlordiazepoxide in the 1950s. ... with Lennox-Gastaut syndrome in adults and children aged two years and older. …
Aceclofenac is an oral non-steroidal anti-inflammatory drug (NSAID) with marked anti-inflammatory and analgesic properties used to treat osteoarthritis, rheumatoid arthritis and ankylosing spondylitis. It is reported to have a higher anti-inflammatory action or at least comparable effects than conventional NSAIDs in double-blind studies [A19667, A19668, A19670]. Aceclofenac potently inhibits the...
Approved
Investigational
Matched Description: … It is a more commonly prescribed drug in Europe. ... modification in effort to improve the gastrointestinal tolerability of the drug. ... It displays high permeability to penetrate into synovial joints where in patients with osteoarthritis …
The World Health Organization declared smallpox, a contagious and sometimes fatal infectious disease, eradicated in 1980. However, there have been longstanding concerns that smallpox may be used as a bioweapon.[A35133,L3614] Tecovirimat is an antiviral drug that was identified via a high-throughput screen in 2002. It is effective against all orthopoxviruses,...
Approved
Investigational
Matched Description: … the approval from the European Commission in January 2022. ... Health Organization declared smallpox, a contagious and sometimes fatal infectious disease, eradicated in ... [A35133,L3614] Tecovirimat is an antiviral drug that was identified via a high-throughput screen in 2002 …
Celiprolol is indicated for the management of mild to moderate hypertension and effort-induced angina pectoris. It is simultaneously a selective β1 receptor antagonist, a β2 receptor partial agonist and a weak α2 receptor antagonist. In 2010 a clinical trial has suggested a use for this medication in the prevention of...
Approved
Investigational
Matched Description: … In 2010 a clinical trial has suggested a use for this medication in the prevention of vascular complications ... Celiprolol is not approved for use by the FDA in the treatment of vascular Ehlers–Danlos syndrome. ... demonstrated decreased incidence of arterial rupture or dissection (a specific type of arterial rupture in
Chloroquine is an aminoquinolone derivative first developed in the 1940s for the treatment of malaria. It was the drug of choice to treat malaria until the development of newer antimalarials such as pyrimethamine, artemisinin, and mefloquine. Chloroquine and its derivative hydroxychloroquine have since been repurposed for the treatment of a...
Approved
Investigational
Vet approved
Matched Description: … Chloroquine is an aminoquinolone derivative first developed in the 1940s for the treatment of malaria ... [A192432] **The FDA emergency use authorization for [hydroxychloroquine] and chloroquine in the treatment …
Sevelamer is a phosphate binding drug used to prevent hyperphosphataemia in patients with chronic renal failure. It is marketed by Genzyme under the trade name Renagel.
Approved
Matched Description: … Sevelamer is a phosphate binding drug used to prevent hyperphosphataemia in patients with chronic renal …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Ethanolamine oleate is a mild sclerosing agent. It is composed of ethanolamine, a basic substance, which when combined with oleic acid forms a clear, straw to pale yellow colored, deliquescent oleate.
Approved
Matched Categories: … Compounds used in a research, industrial, or household setting …
Thiosulfuric acid is available in its salt forms sodium thiosulfate and sodium thiosulfate pentahydrate. Sodium thiosulfate is part of the World Health Organization’s list of essential medicines, and it has a variety of industrial uses, including food preservative, water de-chlorinator and paper pulp bleaching agent. Sodium thiosulfate is rapidly degraded...
Approved
Investigational
Matched Description: … Thiosulfuric acid is available in its salt forms sodium thiosulfate and sodium thiosulfate pentahydrate ... [A252827] Sodium thiosulfate is rapidly degraded in the stomach; therefore, it is normally administered ... approved for the treatment of acute cyanide poisoning[L310,L43332,A252832] and it is frequently used in
Matched Categories: … Compounds used in a research, industrial, or household setting …
Displaying drugs 501 - 525 of 11857 in total