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Displaying drugs 501 - 525 of 713 in total
The anti-obesity drug, V24343, acts by targeting the CB1 receptor in the brain and suppressing a person's appetite.
Investigational
Experimental
Experimental
Tagatose is a functional sweetener. It is a naturally occurring monosaccharide, specifically a hexose. It is commonly found in dairy with a similar texture and sweetened capacity to sucrose but with only a third of the calories. It is approved as a food additive as a low calorie sweetener. Additionally,...
Investigational
Matched Description: … Additionally, it is under investigation by Spherix for the treatment of obesity and type II diabetes. …
Saprisartan is an AT1 receptor antagonist. It is based on medications of losartan's prototypical chemical structure. The mode of (functional) AT1 receptor antagonism has been characterized as insurmountable/noncompetitive for saprisartan. It is very likely that slow dissociation kinetics from the AT1 receptor underlie insurmountable antagonism .
Experimental
Matched Categories: … Angiotensin II receptor antagonists ... Angiotensin II Type 1 Receptor Blockers …
Fimasartan is an angiotensin II receptor antagonist (ARB) drug employed in the treatment of both hypertension and heart failure. It has been found to be safe when administered with hydrochlorothiazide (a diuretic) in clinical trials. Fimasartan was initially approved September 9th, 2010 in South Korea and is marketed under the...
Investigational
Matched Description: … Fimasartan is an angiotensin II receptor antagonist (ARB) drug employed in the treatment of both hypertension …
Matched Categories: … Angiotensin II receptor blockers (ARBs), plain ... Angiotensin II receptor blockers (ARBs) and diuretics ... Angiotensin II receptor blockers (ARBs) and calcium channel blockers …
Experimental
Aleglitazar is an investigational drug from the company Hoffmann–La Roche and is currently in a phase III clinical trial called ALECARDIO. It is being investigated for use in patients with type II diabetes to reduce their risks of cardiovascular mortality and morbidity. Aleglitazar is an agonist at the peroxisome proliferator-activated...
Investigational
Matched Description: … In the phase II clinical trial called SYNCHRONY, with type II diabetic patients, aleglitazar was able ... It is being investigated for use in patients with type II diabetes to reduce their risks of cardiovascular …
Iron(III) oxide or ferric oxide is the inorganic compound with the formula Fe2O3. It is one of the three main oxides of iron, the other two being iron(II) oxide (FeO) the rarer form, and iron(II,III) oxide (Fe3O4) which naturally as magnetite.
Experimental
Matched Description: … and iron(II,III) oxide (Fe3O4) which naturally as magnetite. ... It is one of the three main oxides of iron, the other two being iron(II) oxide (FeO) the rarer form, …
Forasartan, a specific angiotensin II antagonist, is used alone or with other antihypertensive agents to treat hypertension. Forasartan competes with angiotensin II for binding at the AT1 receptor subtype. As angiotensin II is a vasoconstrictor which also stimulates the synthesis and release of aldosterone, blockage of its effects results in...
Experimental
Matched Description: … Forasartan competes with angiotensin II for binding at the AT1 receptor subtype. ... Forasartan, a specific angiotensin II antagonist, is used alone or with other antihypertensive agents ... As angiotensin II is a vasoconstrictor which also stimulates the synthesis and release of aldosterone …
Matched Categories: … Angiotensin II receptor antagonists ... Angiotensin II Type 1 Receptor Blockers …
Ceramide NP is a lipid molecule included in a group of lipid molecules called ceramides. Ceramides are major lipid components in the stratum corneum of the human skin. Ceramide 3 consists of a phytosphingosine backbone N-acylated with a saturated fatty acid (stearic acid) . It is widely used as a...
Experimental
Ferric pyrophosphate is an iron replacement product. Free iron presents several side effects as it can catalyze free radical formation and lipid peroxidation as well as the presence of interactions of iron in plasma. The ferric ion is strongly complexed by pyrophosphate. It presents an increasing interest as this insoluble...
Experimental
Candesartan is an angiotensin-receptor blocker (ARB) that may be used alone or with other agents to treat hypertension. It is available as a prodrug in the form of candesartan cilexetil.
Experimental
Matched Categories: … Angiotensin II receptor antagonists ... Angiotensin II Type 2 Receptor Blockers ... Angiotensin II receptor blockers (ARBs), plain ... Angiotensin II receptor blockers (ARBs) and diuretics ... Angiotensin II receptor blockers (ARBs) and calcium channel blockers …
Investigational
Silmitasertib is under investigation in clinical trial NCT03904862 (Testing the Safety and Tolerability of CX-4945 in Patients With Recurrent Medulloblastoma Who May or May Not Have Surgery).
Investigational
Matched Categories: … Casein Kinase II, antagonists & inhibitors …
XR11576 (MLN576) is a novel monophenazine with a mechanism of action that includes interaction with both topoisomerase (Topo) I and II.
Investigational
Matched Description: … monophenazine with a mechanism of action that includes interaction with both topoisomerase (Topo) I and II
Matched Categories: … Topoisomerase II Inhibitors …
Fluocortin has been studied as a corticosteroid for treatment of dermatitis and eczema Spain .
Experimental
Matched Categories: … Corticosteroids, Moderately Potent (Group II) …
Homidium is a group II compound with trypanocidal effects.
Investigational
Matched Description: … Homidium is a group II compound with trypanocidal effects.[A253017] …
Displaying drugs 501 - 525 of 713 in total