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Displaying drugs 501 - 525 of 12824 in total
Gadolinium
Gadolinium is under investigation in Hypertension, ACUTE KIDNEY INJURY, and Chronic Kidney Disease. Gadolinium has been investigated for the basic science of CAD, Multiple Sclerosis, and Coronary Artery Disease.
Approved
Investigational
Matched Description: … Gadolinium is under investigation in Hypertension, ACUTE KIDNEY INJURY, and Chronic Kidney Disease. …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Distearyldimonium
Approved
Experimental
Matched Categories: … Compounds used in a research, industrial, or household setting …
Microcrystalline cellulose
A polysaccharide with glucose units linked as in CELLOBIOSE. It is the chief constituent of plant fibers, cotton being the purest natural form of the substance. As a raw material, it forms the basis for many derivatives used in chromatography, ion exchange materials, explosives manufacturing, and pharmaceutical preparations.
Approved
Experimental
Investigational
Matched Description: … A polysaccharide with glucose units linked as in CELLOBIOSE. ... As a raw material, it forms the basis for many derivatives used in chromatography, ion exchange materials …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Patent Blue
Patent blue is aniline dye and it is one of the most common dyes used. It is a sodium or calcium salt of diethylammonium hydroxide inner salt. It has the chemical designation of (4-(alpha-(p-(diethylamino)phenyl)-2,4-disulfobenzylidene)-2,5-cyclohexadiene-1-ylidene)diethylammonium hydroxide. Patent blue was developed by Guerbet and approved by Health Canada on December 31, 1979....
Approved
Matched Description: … [L1113] The isomer isosulphan is used in the United States for the same indications than patent blue. …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Carbon monoxide
Carbon monoxide (CO) is a colorless, odorless, and tasteless gas that has a slightly lower density than air. It is toxic to hemoglobin utilizing animals (including humans), when encountered in concentrations above about 35 ppm, although it is also formed in normal animal metabolism in low quantities, and is thought...
Approved
Investigational
Matched Description: … about 35 ppm, although it is also formed in normal animal metabolism in low quantities, and is thought ... Carbon monoxide is presently used in small amounts in low oxygen modified atmosphere packaging systems ... In New Zealand, the use of carbon monoxide in fish preparation has been banned, as it may mask the effects …
Corn
Corn allergenic extract is used in allergenic testing.
Approved
Matched Description: … Corn allergenic extract is used in allergenic testing. …
Bezlotoxumab
Bezlotoxumab is a fully humanized ImmunoglobulinG1 (IgG1) kappa monoclonal antibody that binds to Clostridium difficile toxin B and neutralizes its effects. First approved by the FDA on October 21, 2016, bezlotoxumab is used to reduce the recurrence of C. difficile infection. On November 22, 2016, the Committee for Medicinal Products...
Approved
Investigational
CVac
Approved
Investigational
Artesunate
Artesunate is indicated for the initial treatment of severe malaria. The World Health Organization recommends artesunate as first line treatment for severe malaria. Artesunate was developed out of a need for a more hydrophilic derivative of artemisinin. Artesunate was granted FDA approval on 26 May 2020.
Approved
Investigational
Cipaglucosidase alfa
Cipaglucosidase alfa (ATB200) is a novel recombinant human acid alpha-glucosidase (GAA) investigated for the treatment of patients with Pompe disease, a rare inherited metabolic disorder characterized by a deficiency in GAA. Other types of enzyme replacement therapy for the treatment of Pompe disease include alglucosidase alfa and avalglucosidase alfa. Cipaglucosidase...
Approved
Investigational
Matched Description: … skeletal muscle, one of the main affected tissues in Pompe disease. ... phosphate (M6P) N-glycans that bind to the cation-independent mannose-6-phosphate receptor (CI-MPR) in ... [A232955, A232960]
In December 2022, the EMA's Committee for Medicinal Products for Human Use (CHMP …
Ceftazidime
Bacteria possess a cell wall comprising a glycopeptide polymer commonly known as peptidoglycan, which is synthesized and remodelled through the action of a family of enzymes known as "penicillin-binding proteins" (PBPs). β-lactam antibiotics, including cephalosporins, are PBP inhibitors that, through inhibition of essential PBPs, result in impaired cell wall homeostasis,...
Approved
Matched Description: … Ceftazidime was approved by the FDA on July 19, 1985, and is currently available either alone or in ... antibiotics, including cephalosporins, are PBP inhibitors that, through inhibition of essential PBPs, result in …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... Heterocyclic Compounds, Fused-Ring …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... Heterocyclic Compounds, Fused-Ring …
Crotamiton
Crotamiton is a scabicidal and antipruritic agent available as a cream or lotion for topical use only. It is a colorless to slightly yellowish oil, having a faint amine-like odor. It is miscible with alcohol and with methanol.
Approved
Matched Categories: … Compounds used in a research, industrial, or household setting …
Cyclizine
A histamine H1 antagonist given by mouth or parenterally for the control of postoperative and drug-induced vomiting and in motion sickness. (From Martindale, The Extra Pharmacopoeia, 30th ed, p935)
Approved
Matched Description: … antagonist given by mouth or parenterally for the control of postoperative and drug-induced vomiting and in …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Erythrityl tetranitrate
A vasodilator with general properties similar to nitroglycerin. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1020)
Approved
Experimental
Investigational
Matched Categories: … Vasodilators Used in Cardiac Diseases …
Bentonite
Approved
Matched Categories: … Compounds used in a research, industrial, or household setting …
Cetalkonium
Cetalkonium is a C16 alkyl benzalkonium chloride derivative with an amphipathic property which allows it to be used in different types of formulations. It is a quaternary ammonium salt that acts as an antiseptic against a variety of bacteria and fungi. Cetalkonium is approved by the FDA for its use...
Approved
Matched Description: … C16 alkyl benzalkonium chloride derivative with an amphipathic property which allows it to be used in ... [L2737] By Health Canada, it is also approved for its use in over-the-counter products.[L1113] ... [L2137] Cetalkonium is approved by the FDA for its use in over-the-counter products as a skin protectant …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Bromothalonil
Bromothalonil, also known as Methyldibromo glutaronitrile (MDBGN), is a widely used preservative that can be found in many personal hygiene and industrial products. It is also a known allergen and dermatological irritant that has been banned in many EU countries due to increasing rates of contact allergy . In 2005,...
Approved
Experimental
Matched Description: … In 2005, MDBGN was named in the top 15 most frequently positive allergens identified in patch tests by ... also known as Methyldibromo glutaronitrile (MDBGN), is a widely used preservative that can be found in ... It is also a known allergen and dermatological irritant that has been banned in many EU countries due …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Pentoxifylline
Pentoxifylline (PTX) is a synthetic dimethylxanthine derivative that modulates the rheological properties of blood and also has both anti-oxidant and anti-inflammatory properties.[A226415, L30300] Although originally developed to treat intermittent claudication, a form of exertion-induced leg pain common in patients with peripheral arterial disease, PTX has been investigated for its possible...
Approved
Investigational
Matched Description: … originally developed to treat intermittent claudication, a form of exertion-induced leg pain common in ... patients with peripheral arterial disease, PTX has been investigated for its possible use in diverse ... [A226608]
Pentoxifylline has been marketed in Europe since 1972; PTX extended-release tablets sold …
Matched Categories: … Compounds used in a research, industrial, or household setting ... Heterocyclic Compounds, 2-Ring ... Heterocyclic Compounds, Fused-Ring …
Matched Categories: … Compounds used in a research, industrial, or household setting ... Heterocyclic Compounds, 2-Ring ... Heterocyclic Compounds, Fused-Ring …
Simethicone
Simethicone is a silicon based surfactant that decreases the surface tension of gastrointestinal gas bubbles to facilitate their elimination. It has a favourable safety profile as it is not systemically absorbed. Simethicone has been in use since the 1940s but was granted FDA approval in 1952.
Approved
Matched Description: … [A228308]
Simethicone has been in use since the 1940s[A228303] but was granted FDA approval in 1952 …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Methylcellulose
Methyl cellulose polymer consisting of numerous linked glucose molecules used as a stabiliser, thickener and emulsifier for foodstuffs and cosmetics. The Degree of Substitution (DS) of a given form of methyl cellulose is defined as the average number of substituted hydroxyl groups per glucose with a theoretical maximum of 3,...
Approved
Matched Description: … Methyl cellulose is a hydrophilic white powder in pure form and dissolves in cold (but not in hot) water …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Influenza A virus A/West Virginia/30/2022 (H1N1) Recombinant Hemagglutinin Antigen
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that helps to protect against infection from influenza viruses. These vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which results in...
Approved
Matched Description: … , or inactivated, through exposure to heat or chemicals such as formaldehyde. ... Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed ... protection from influenza by exposing the immune system to the virus (or parts of the virus) which results in …
Influenza A virus A/Victoria/4897/2022 IVR-238 (H1N1) Antigen (propiolactone inactivated)
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that helps to protect against infection from influenza viruses. These vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which results in...
Approved
Matched Description: … , or inactivated, through exposure to heat or chemicals such as formaldehyde. ... Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed ... protection from influenza by exposing the immune system to the virus (or parts of the virus) which results in …
Apalutamide
Apalutamide is a potent androgen receptor (AR) antagonist that selectively binds to the ligand-binding domain of AR and blocks AR nuclear translocation or binding to androgen response elements . It has been used in trials studying the treatment of Prostate Cancer, Hepatic Impairment, Prostatic Neoplasms, Castration-Resistant Prostate Cancer, and Prostatic...
Approved
Investigational
Matched Description: … In mice bearing human CRPC xenograft models, apalutamide treatment produced tumor regressions in a dose-dependent ... Apalutamide displayed good tolerability and safety profile in clinical studies. ... It has been used in trials studying the treatment of Prostate Cancer, Hepatic Impairment, Prostatic Neoplasms …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Denosumab
Denosumab is a novel, fully human IgG2 monoclonal antibody specific to receptor activator of nuclear factor kappa-B ligand (RANKL), suppresses bone resorption via inhibiting RANK-mediated activation of osteoclasts. It is the first and currently the only RANKL inhibitor approved to prevent osteoclast-mediated bone loss. Chemically, it consists of 2 heavy...
Approved
Matched Description: … September 2011 and in men with osteoporosis at high risk for fracture in September 2012. ... and women at high risk for fracture receiving adjuvant aromatase inhibitor therapy for breast cancer in ... It further received additional indication approval to increase bone mass in men at high risk for fracture …
Displaying drugs 501 - 525 of 12824 in total