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Displaying drugs 5226 - 5250 of 11617 in total
Avasopasem manganese, also known as GC4419, is a highly-selective small molecule mimetic of superoxide dismutase (SOD) being investigated for the reduction of radiation-induced severe oral mucositis.[L27246, L27256] This drug has potential application for radiation-induced esophagitis and oral mucositis, in addition to being currently tested against COVID-19.
Investigational
Matched Description: … Avasopasem manganese, also known as GC4419, is a highly-selective small molecule mimetic of superoxide …
Apadenoson is a selective A2a adenosine receptor agonist designed for use as a pharmacologic stress agent in cardiac perfusion imaging studies. It is developed by Bristol-Myers Squibb and is in phase II of clinical trials.
Investigational
Matched Description: … Apadenoson is a selective A2a adenosine receptor agonist designed for use as a pharmacologic stress agent …
Matched Categories: … Adenosine A receptor agonists …
Proscillaridin is a cardiac glycoside that is derived from plants of the genus Scilla and in Drimia maritima (Scilla maritima). Studies suggest the potential cytotoxic and anticancer property of proscillaridin, based on evidence of the drug potently disrupting topoisomerase I and II activity at nanomolar drug concentrations and triggering cell...
Experimental
Matched Description: … Proscillaridin is a cardiac glycoside that is derived from plants of the genus Scilla and in Drimia maritima …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Experimental
Matched Categories: … Compounds used in a research, industrial, or household setting …
Experimental
Matched Categories: … Compounds used in a research, industrial, or household setting …
An antidepressive agent and monoamine oxidase inhibitor related to PARGYLINE.
Experimental
Matched Categories: … Monoamine Oxidase A Inhibitors …
Vitamin A-analog that increases diffusivity of oxygen in aqueous solutions, including plasma.
Investigational
Matched Description: … Vitamin A-analog that increases diffusivity of oxygen in aqueous solutions, including plasma. …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Vet approved
Matched Categories: … Compounds used in a research, industrial, or household setting …
Experimental
Matched Categories: … Compounds used in a research, industrial, or household setting …
Droloxifene, a derivative of the triphenylethylene drug tamoxifen, is a novel selective estrogen receptor modulator (SERM). Droloxifene also exhibits more rapid pharmacokinetics, reaching peak concentrations and being eliminated much more rapidly than tamoxifen. Its higher affinity to the estrogen receptor, higher anti-estrogenic to estrogenic ratio, more effective inhibition of cell...
Investigational
Matched Description: … Droloxifene, a derivative of the triphenylethylene drug tamoxifen, is a novel selective estrogen receptor ... It may have a particular role in situations in which rapid pharmacokinetics, or an increased antiestrogenic ... Droloxifene may also be a potentially useful agent for the treatment of postmenopausal osteoporosis because …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Methyl-1-testosterone is a synthetic and orally active anabolic–androgenic steroid (AAS) which was never marketed for medical use. It is a derivative of 1-testosterone with a methyl group in the carbon 17. Methyl-1-testosterone is considered a prohibited doping substance.
Experimental
Illicit
Matched Iupac: … 11aS)-1-hydroxy-1,9a,11a-trimethyl-1H,2H,3H,3aH,3bH,4H,5H,5aH,6H,7H,9aH,9bH,10H,11H,11aH-cyclopenta[a] …
Matched Description: … It is a derivative of 1-testosterone with a methyl group in the carbon 17. ... Methyl-1-testosterone is considered a prohibited doping substance. ... Methyl-1-testosterone is a synthetic and orally active anabolic–androgenic steroid (AAS) which was never …
BQ-123 has been investigated for the basic science and treatment of Coronary Artery Disease, Aorto-coronary Bypass Grafting, and ST-Elevation Myocardial Infarction.
Investigational
Matched Iupac: … 1H-indol-3-yl)methyl]-6-(2-methylpropyl)-1,4,7,10,13-pentaoxo-3-(propan-2-yl)-hexadecahydro-1H-pyrrolo[1,2-a] …
Trestolone acetate is a synthetic and injected anabolic–androgenic steroid (AAS) and a derivative of nandrolone (19-nortestosterone) which was never marketed. It is an androgen ester – specifically, the C17 acetate ester of DB05830.
Experimental
Matched Iupac: … ,9aR,9bS,11aS)-4,11a-dimethyl-7-oxo-1H,2H,3H,3aH,3bH,4H,5H,7H,8H,9H,9aH,9bH,10H,11H,11aH-cyclopenta[a] …
Matched Description: … Trestolone acetate is a synthetic and injected anabolic–androgenic steroid (AAS) and a derivative of …
Illicit
Vet approved
Matched Iupac: … 3aS,3bR,9aR,9bS,11aS)-9a,11a-dimethyl-7-oxo-1H,2H,3H,3aH,3bH,4H,5H,7H,9aH,9bH,10H,11H,11aH-cyclopenta[a] …
An adrenocortical steroid that has modest but significant activities as a mineralocorticoid and a glucocorticoid. (From Goodman and Gilman's The Pharmacological Basis of Therapeutics, 8th ed, p1437)
Experimental
Matched Iupac: … 1-(2-hydroxyacetyl)-9a,11a-dimethyl-1H,2H,3H,3aH,3bH,4H,5H,7H,8H,9H,9aH,9bH,10H,11H,11aH-cyclopenta[a] …
Matched Description: … An adrenocortical steroid that has modest but significant activities as a mineralocorticoid and a glucocorticoid …
Combretastatin has been investigated for the treatment of Anaplastic Thyroid Cancer.
Investigational
An arsenical which has been used as a feed additive for enteric conditions in pigs and poultry. It causes blindness and is ototoxic and nephrotoxic in animals. [PubChem]
Experimental
Vet approved
Matched Description: … An arsenical which has been used as a feed additive for enteric conditions in pigs and poultry. …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Experimental
Matched Categories: … Drugs that are Mainly Renally Excreted with a Narrow Therapeutic Index …
Experimental
Matched Categories: … Compounds used in a research, industrial, or household setting …
Butylphthalide has been used in trials studying the prevention of Restenosis.
Investigational
Matched Categories: … Compounds used in a research, industrial, or household setting …
Investigational
Matched Categories: … Compounds used in a research, industrial, or household setting …
1-Testosterone is an anabolic steroid that differs from testosterone by having a 1,2-double bond instead of 4,5-double bond in its A ring.
Experimental
Illicit
Investigational
Matched Iupac: … 9bS,11aS)-1-hydroxy-9a,11a-dimethyl-1H,2H,3H,3aH,3bH,4H,5H,5aH,6H,7H,9aH,9bH,10H,11H,11aH-cyclopenta[a] …
Matched Description: … of 4,5-double bond in its A ring. ... 1-Testosterone is an anabolic steroid that differs from testosterone by having a 1,2-double bond instead …
A 17-alkylated orally active androgenic steroid. A Schedule IV drug in Canada.
Experimental
Illicit
Matched Iupac: … 11aS)-1-hydroxy-1,4,9a,11a-tetramethyl-1H,2H,3H,3aH,3bH,4H,5H,7H,8H,9H,9aH,9bH,10H,11H,11aH-cyclopenta[a] …
Matched Description: … A 17-alkylated orally active androgenic steroid. A Schedule IV drug in Canada. …
Experimental
Matched Iupac: … 11aS)-1-hydroxy-9,9a,11a-trimethyl-1H,2H,3H,3aH,3bH,4H,5H,5aH,6H,7H,9aH,9bH,10H,11H,11aH-cyclopenta[a] …
Experimental
Matched Iupac: … 9aR,9bS,11aS)-9a,11a-dimethyl-7-oxo-1H,2H,3H,3aH,3bH,4H,5H,7H,8H,9H,9aH,9bH,10H,11H,11aH-cyclopenta[a] …
Displaying drugs 5226 - 5250 of 11617 in total