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Displaying drugs 526 - 550 of 746 in total

Equol

Equol has been used in trials studying the treatment of Breast Cancer.
Investigational
Matched Synonyms: … S-equol …
Matched Name: … Equol …
Matched Description: … Equol has been used in trials studying the treatment of Breast Cancer. …
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists …

Susoctocog alfa

Intravenous susoctocog alfa is a recombinant, B-domain deleted, porcine sequence antihaemophilic factor VIII (FVIII) product that has recently been approved for the treatment of bleeding episodes in adults with acquired haemophilia A (AHA). AHA is a rare bleeding disorder that results in a prolonged clotting time as measured by the...
Approved
Investigational
Matched Synonyms: … SCROFA, GLYCOSYLATED ... ANALOGUE, PRODUCED IN BHK21 CELLS: DES-(753-1418)-BLOOD-COAGULATION FACTOR VIII (PROCOAGULANT COMPONENT) SUS …
Matched Description: … These autoantibodies neutralize circulating human factor VIII and create a functional deficiency of this ... Susoctocog alfa was approved by the FDA in October 2014 and is marketed under the brand name Obizur for ... porcine FVIII treatment approved for AHA that allows physicians to manage the treatment's efficacy and …
Matched Categories: … Blood and Blood Forming Organs …

Retlirafusp alfa

Investigational
Matched Synonyms: … musculus monoclonal SHR-1316 .kappa. ... 227-proline, 233-alanine, 234-alanine, 446-alanine), anti-(human programmed death-ligand 1) (human-mus ... musculus monoclonal SHR-1316 .gamma.4-chain) fusion protein with peptide linker ((ggggs)4g) fusion protein …
Matched Categories: … Amino Acids, Peptides, and Proteins …

Tauroursodeoxycholic acid

Tauroursodeoxycholic acid, also known as ursodoxicoltaurine, is a highly hydrophilic tertiary bile acid that is produced in humans at a low concentration. It is a taurine conjugate of ursodeoxycholic acid with comparable therapeutic efficacy and safety, but a much higher hydrophilicity. Normally, hydrophilic bile acids regulates hydrophobic bile acids and...
Approved
Investigational
Matched International brands: … Tauro …
Matched Description: … It is a taurine conjugate of [ursodeoxycholic acid] [A249065] with comparable therapeutic efficacy and ... the body's intake of dietary cholesterol and the body cholesterol content. ... [A249060] Normally, hydrophilic bile acids regulates hydrophobic bile acids and their cytotoxic effects …
Matched Categories: … Alimentary Tract and Metabolism ... Bile acids and derivatives ... Bile Acids and Salts ... Bile and Liver Therapy ... Cholagogues and Choleretics …
Matched Products: … TAURO …

Cendakimab

Cendakimab is a recombinant humanized anti-interleukin 13 (IL-13) monoclonal antibody.
Investigational
Matched Synonyms: … RPC4046 .GAMMA.-1), DISULFIDE WITH HUMAN-MUS MUSCULUS MONOCLONAL RPC4046 .KAPPA.-1, DIMER ... IMMUNOGLOBULIN G1(240-ALANINE, 241-ALANINE), ANTI-(HUMAN INTERLEUKIN 13) (HUMAN-MUS MUSCULUS MONOCLONAL …
Matched Categories: … Amino Acids, Peptides, and Proteins …

Lirentelimab

Lirentelimab is under investigation in clinical trial NCT04856891 (A Study of Lirentelimab (AK002) in Patients With Active Eosinophilic Duodenitis).
Investigational
Matched Synonyms: … AK002 .GAMMA.1-CHAIN), DISULFIDE WITH HUMAN-MUS MUSCULUS MONOCLONAL AK002 .KAPPA. ... IMMUNOGLOBULIN G1, ANTI-(HUMAN SIALIC ACID-BINDINGE IG-LIKE LECTIN 8) (HUMAN-MUS MUSCULUS MONOCLONAL ... MONOCLONAL ANTIBODY.GAMMA.1 HEAVY CHAIN (1-450) (VH (HOMO SAPIENS IGHV3-66*01 (79%) (IGHD)-IGHJ5*01 (91%)/MUS …
Matched Categories: … Amino Acids, Peptides, and Proteins …

Lorazepam

Lorazepam is a short-acting and rapidly cleared benzodiazepine used commonly as a sedative and anxiolytic. It was developed by DJ Richards, presented and marketed initially by Wyeth Pharmaceuticals in the USA in 1977. The first historic FDA label approval is reported in 1985 by the company Mutual Pharm.
Approved
Matched Description: … Lorazepam is a short-acting and rapidly cleared benzodiazepine used commonly as a sedative and anxiolytic ... [A957] It was developed by DJ Richards, presented and marketed initially by Wyeth Pharmaceuticals in …
Matched Categories: … Benzodiazepine hypnotics and sedatives ... Benzodiazepines and benzodiazepine derivatives ... Hypnotics and Sedatives …
Matched Products: … ANSIL …

Elranatamab

Elranatamab is a bispecific B-cell maturation antigen (BCMA)-directed CD3 T-cell engager. It is a humanized immunoglobulin 2-alanine kappa antibody derived from two monoclonal antibodies (mAbs), an anti-BCMA mAb and an anti-CD3 mAb, each of which contributes one heavy chain and one light chain to drug structure. The resulting 4-chain bispecific...
Approved
Investigational
Matched Synonyms: … -CHAIN) (HUMAN-MUS MUSCULUS MONOCLONAL PF-06863059 .GAMMA.2-CHAIN), DISULFIDE WITH HUMAN-MUS MUSCULUS ... MUSCULUS MONOCLONAL DISULFIDE WITH IMMUNOGLOBULIN G2-KAPPA, ANTI-(HOMO SAPIENS-TUMOR NECROSIS FACTO ... SURFACE GLYCOPROTEIN CD3 EPSILON CHAIN CD3E (T-CELL SURFACE ANTIGEN T3/LEU-4 EPSILON CHAIN)), HUMAN-MUS …
Matched Description: … immunoglobulin 2-alanine kappa antibody derived from two monoclonal antibodies (mAbs), an anti-BCMA mAb and ... an anti-CD3 mAb,[A261060] each of which contributes one heavy chain and one light chain to drug structure …
Matched Categories: … Amino Acids, Peptides, and Proteins …

Sabatolimab

Sabatolimab is under investigation in clinical trial NCT03946670 (A Study of MBG453 in Combination With Hypomethylating Agents in Subjects With IPSS-R Intermediate, High or Very High Risk Myelodysplastic Syndrome (MDS).).
Investigational
Matched Synonyms: … musculus monoclonal clone nvs260714 .gamma.4-chain), disulfide with human-mus musculus monoclonal clone ... Immunoglobulin g4 (226-proline,de-c-terminal-lysine), anti-(human hepatitis virus a cellular receptor 2) (human-mus …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES …

MOR-22

MOR-22, a Natural human lymphoblastoid interferon-alpha, is currently being investigated to treat papillomavirus warts in the oral cavity of HIV-positive patients.
Investigational
Matched Name: … MOR-22 …
Matched Description: … warts in the oral cavity of HIV-positive patients. ... MOR-22, a Natural human lymphoblastoid interferon-alpha, is currently being investigated to treat papillomavirus …

Cisapride

In many countries (including Canada) cisapride has been either withdrawn or has had its indications limited due to reports about long QT syndrome due to cisapride, which predisposes to arrhythmias. The FDA issued a warning letter regarding this risk to health care professionals and patients.
Approved
Investigational
Withdrawn
Matched Description: … The FDA issued a warning letter regarding this risk to health care professionals and patients. …
Matched Categories: … Alimentary Tract and Metabolism ... Benzamides and benzamide derivatives …
Matched Products: … Prepulsid Sus 1mg/ml …

Cortisone acetate

Cortisone acetate was first isolate in 1935 and became more widely researched in 1949. Since then, glucocorticoids such as cortisone acetate have been used to treat a number of inflammatory conditions such as endocrine, rheumatic, collagen, dermatologic, allergic, ophthalmic, respiratory, hematologic, neoplastic, edematous, and gastrointestinal diseases and disorders.[A226300,L13203] Cortisone acetate...
Approved
Investigational
Matched Description: … Cortisone acetate was first isolate in 1935 and became more widely researched in 1949. ... gastrointestinal diseases and disorders. ... rheumatic, collagen, dermatologic, allergic, ophthalmic, respiratory, hematologic, neoplastic, edematous, and …
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … Cortone Sus 50mg/ml …

Magrolimab

Magrolimab is under investigation in clinical trial NCT02953782 (Trial of Magrolimab (Hu5f9-g4) in Combination With Cetuximab in Participants With Solid Tumors and Advanced Colorectal Cancer).
Investigational
Matched Synonyms: … .4-chain), disulfide with human-mus musculus monoclonal hu5f9-g4 .kappa. ... Immunoglobulin g4(225-proline), anti-(human cd47 antigen) (human-mus musculus monoclonal hu5f9-g4 .gamma …
Matched Description: … NCT02953782 (Trial of Magrolimab (Hu5f9-g4) in Combination With Cetuximab in Participants With Solid Tumors and …
Matched Categories: … Amino Acids, Peptides, and Proteins …

Hepatitis A Vaccine

Hepatitis A viral infection can lead to significant morbidity and mortality, with signs and symptoms that include anorexia, nausea, vomiting, and liver failure. Known by several trade names, such as Havrix and Twinrix, the Hepatitis A vaccine has been formulated for immunization against hepatitis A virus (HAV) infection and safely...
Approved
Matched Description: … Hepatitis A viral infection can lead to significant morbidity and mortality, with signs and symptoms ... that include anorexia, nausea, vomiting, and liver failure. ... [A199182] Known by several trade names, such as Havrix and Twinrix, the Hepatitis A vaccine has been …
Matched Products: … Havrix - 720unit/ml Sus ... Havrix - Sus Im 1440 Elisa Units/ml …

Levocabastine

Levocabastine is a selective second-generation H1-receptor antagonist used for allergic conjunctivitis. Levocabastine was discovered at Janssen Pharmaceutica in 1979.
Approved
Investigational
Matched Categories: … Decongestants and Antiallergics …
Matched Products: … Livostin Sus Nas 0.5mg/ml …

PRTX-100

PRTX-100 is a highly-purified form of Staphylococcal Protein A that binds directly to monocytes and a subset of B-cells that are involved in the development and progression of various autoimmune diseases. These binding interactions enable the compound to modulate the function of these cells and restore the balance of the...
Investigational
Matched Synonyms: … Staphylococcus aureus protein A …
Matched Description: … PRTX-100 is a highly-purified form of Staphylococcal Protein A that binds directly to monocytes and a ... subset of B-cells that are involved in the development and progression of various autoimmune diseases ... These binding interactions enable the compound to modulate the function of these cells and restore the …

Magnesium hydroxide

Magnesium hydroxide is an inorganic compound. It is naturally found as the mineral brucite. Magnesium hydroxide can be used as an antacid or a laxative in either an oral liquid suspension or chewable tablet form. Additionally, magnesium hydroxide has smoke suppressing and flame retardant properties and is thus used commercially...
Approved
Investigational
Matched Description: … Additionally, magnesium hydroxide has smoke suppressing and flame retardant properties and is thus used ... It can also be used topically as a deodorant or for the relief of canker sores (aphthous ulcers). ... Magnesium hydroxide can be used as an antacid or a laxative in either an oral liquid suspension or chewable …
Matched Mixtures name: … PMS-alumina Mag and Simethicone Sus ... Antacid Sus ... Antacid and Antigas …
Matched Categories: … Alimentary Tract and Metabolism ... Antacids and Adsorbents ... Aluminum and magnesium containing antacids ... Basic Ointments and Protectants ... Emollients Demulcents and Protectants …
Matched Products: … . - Sus 400mg ... . - Sus 400mg/5ml ... Milk Of Magnesia-sus 400mg/5ml …

Prednisolone acetate

Prednisolone acetate is a prednisolone molecule bound to an acetate functional group by an ester bond. Prednisolone acetate was granted FDA approval in 1955.
Approved
Vet approved
Matched Mixtures name: … Metimyd Oph Sus …
Matched Products: … Ak Tate Oph Sus 1% …

Capric acid

Decanoic acid is a solid. This compound belongs to the straight chain fatty acids. These are fatty acids with a straight aliphatic chain. The proteins that decanoic acid targets include furin, octanoyltransferase, 3-oxoacyl-[acyl-carrier-protein] synthase 1, peptostreptococcal albumin-binding protein, and putative uncharacterized protein tcp14.
Experimental
Matched Synonyms: … Capric acid ... n-capric acid …
Matched Name: … Capric acid …
Matched Description: … octanoyltransferase, 3-oxoacyl-[acyl-carrier-protein] synthase 1, peptostreptococcal albumin-binding protein, and …

Iodide I-131

Iodide I-131 (as Sodium iodide I-131) is a radioisotopic drug used for the treatment and palliation of thyroid malignancy. Iodine-131 is notable for causing mutation and death in cells that it penetrates, which is due to its mode of beta decay. As a result of beta decay, approximately 10% of...
Approved
Investigational
Matched Description: … Iodide I-131 (as Sodium iodide I-131) is a radioisotopic drug used for the treatment and palliation of ... Iodine-131 is notable for causing mutation and death in cells that it penetrates, which is due to its ... As a result of beta decay, approximately 10% of its energy and radiation dose is via gamma radiation, …
Matched Products: … ANSTO - Sodium Iodide [131I] Therapy Capsules (50 to 6000 MBq) …

Nitrofurantoin

Nitrofurantoin is a nitrofuran antibiotic used to treat uncomplicated urinary tract infections.[L6856,L6859,L6862] Nitrofurantoin is converted by bacterial nitroreductases to electrophilic intermediates which inhibit the citric acid cycle as well as synthesis of DNA, RNA, and protein. This drug is more resistant to the development of bacterial resistance because it acts...
Approved
Vet approved
Matched Description: … to electrophilic intermediates which inhibit the citric acid cycle as well as synthesis of DNA, RNA, and ... [A179824] This drug is more resistant to the development of bacterial resistance because it acts on many …
Matched Products: … Novo-furan Sus 25mg/5ml ... Macrodantin Cap 25mg ... Macrodantin Cap 50mg …

Irbesartan

Irbesartan is an angiotensin receptor blocker (ARB) indicated to treat hypertension or diabetic nephropathy.[L7456,L7459] It can also be used as part of a combination product with hydrochlorothiazide for patients not well controlled or not expected to be well controlled on monotherapy. Unlike angiotensin converting enzyme inhibitors, ARBs are not associated...
Approved
Investigational
Matched Description: … [L7456,L7459] It can also be used as part of a combination product with [hydrochlorothiazide] for patients …
Matched Mixtures name: … HIRBES PLUS 300/25 MG FILM KAPLI TABLET, 28 ADET ... HIRBES PLUS 300/25 MG FILM KAPLI TABLET, 90 ADET ... HIRBES PLUS 150/12.5 MG FILM KAPLI TABLET, 28 ADET …
Matched Categories: … Angiotensin II receptor blockers (ARBs) and diuretics ... Angiotensin II receptor blockers (ARBs) and calcium channel blockers ... irbesartan and diuretics ... irbesartan and amlodipine ... irbesartan, amlodipine and hydrochlorothiazide …
Matched Products: … HIRBES 75 MG FILM KAPLI TABLET, 28 ADET ... HIRBES 75 MG FILM KAPLI TABLET, 90 ADET ... HIRBES 150 MG FILM KAPLI TABLET, 28 ADET …

Ulviprubart

Investigational
Matched Synonyms: … monoclonal ABC008 γ1-chain), disulfide with human-Mus musculus monoclonal ABC008 κ-chain, dime ... Immunoglobulin G1, anti-(human killer cell lectin-like receptor subfamily G member 1) (human-Mus musculus …

Domperidone

A specific blocker of dopamine receptors. It speeds gastrointestinal peristalsis, causes prolactin release, and is used as antiemetic and tool in the study of dopaminergic mechanisms.
Approved
Investigational
Vet approved
Matched Description: … It speeds gastrointestinal peristalsis, causes prolactin release, and is used as antiemetic and tool …
Matched Categories: … Alimentary Tract and Metabolism …
Matched Products: … GALFLUX …

Tonabacase

Investigational
Matched Synonyms: … Staphylococcus aureus phage 1 (sap-1)-derived soluble endolysin (staphylococcus aureus phage lysin-1, …
Displaying drugs 526 - 550 of 746 in total