Displaying drugs 526 - 550 of 710 in total
Benzoylecgonine
Benzoylecgonine is the major metabolite of cocaine. It is formed by hydrolysis of cocaine in the liver, catalysed by carboxylesterases. It is excreted in the urine of cocaine users after processing in the liver. It is the main pharmaceutical ingredient in the investigational drug Esterom, a topical solution used for...
Experimental
Illicit
Matched Synonyms: … O-benzoylecgonine ... O-benzoyl-(-)-ecgonine ... (1R,2R,3S,5S)-8-methyl-3-[(phenylcarbonyl)oxy]-8-azabicyclo[3.2.1]octane-2-carboxylic acid …
Matched Description: … muscle pain that is not FDA approved or on the market in the United States. ... Benzoylecgonine is the major metabolite of cocaine. ... It is excreted in the urine of cocaine users after processing in the liver. …
Matched Description: … muscle pain that is not FDA approved or on the market in the United States. ... Benzoylecgonine is the major metabolite of cocaine. ... It is excreted in the urine of cocaine users after processing in the liver. …
Exaluren
Investigational
Matched Synonyms: … 6-(R)-Methyl-5-O-(5-amino-5,6-dideoxy-a-L-talofuranosyl)-paromamine ... 6'-(R)-Methyl-5-O-(5-amino-5,6-dideoxy-a-L-talofuranosyl)-paromamine …
Matched Iupac: … }-3-hydroxycyclohexyl]oxy}-2-[(1R)-1-hydroxyethyl]oxane-3,4-diol ... amino-6-{[(1R,2R,3S,4R,6S)-4,6-diamino-2-{[(2S,3R,4S,5R)-5-[(1S)-1-aminoethyl]-3,4-dihydroxyoxolan-2-yl]oxy …
Matched Iupac: … }-3-hydroxycyclohexyl]oxy}-2-[(1R)-1-hydroxyethyl]oxane-3,4-diol ... amino-6-{[(1R,2R,3S,4R,6S)-4,6-diamino-2-{[(2S,3R,4S,5R)-5-[(1S)-1-aminoethyl]-3,4-dihydroxyoxolan-2-yl]oxy …
Salicylamide
Salicylamide is the common name for the substance o-hydroxybenzamide, or amide of salicyl. Salicylamide is a non-prescription drug with analgesic and antipyretic properties. It has similar medicinal uses to aspirin. Salicylamide is used in combination with both aspirin and caffeine in the over-the-counter pain remedies
Approved
Matched Synonyms: … OHB ... o-hydroxybenzamide …
Matched Description: … Salicylamide is a non-prescription drug with analgesic and antipyretic properties. ... Salicylamide is the common name for the substance o-hydroxybenzamide, or amide of salicyl. ... Salicylamide is used in combination with both aspirin and caffeine in the over-the-counter pain remedies …
Matched Mixtures name: … Green Guard Pain and Ache Relief ... SEMOR PAIN AND FEVER RELIEF CAPSULES …
Matched Categories: … Salicylic Acid and Derivatives …
Matched Description: … Salicylamide is a non-prescription drug with analgesic and antipyretic properties. ... Salicylamide is the common name for the substance o-hydroxybenzamide, or amide of salicyl. ... Salicylamide is used in combination with both aspirin and caffeine in the over-the-counter pain remedies …
Matched Mixtures name: … Green Guard Pain and Ache Relief ... SEMOR PAIN AND FEVER RELIEF CAPSULES …
Matched Categories: … Salicylic Acid and Derivatives …
Aconiazide
Investigational
Matched Synonyms: … Isonicotinic acid (o-(carboxymethoxy)benzylidene)hydrazide …
Matched Categories: … Drugs for Treatment of Tuberculosis …
Matched Categories: … Drugs for Treatment of Tuberculosis …
Meropenem
Meropenem is a broad-spectrum carbapenem antibiotic. It is active against Gram-positive and Gram-negative bacteria. Meropenem exerts its action by penetrating bacterial cells readily and interfering with the synthesis of vital cell wall components, which leads to cell death.
In August 2017, a combination antibacterial therapy under the market name vabomere...
Approved
Investigational
Matched Synonyms: … 4R,5S,6S)-3-{[(3S,5S)-5-(dimethylcarbamoyl)pyrrolidin-3-yl]thio}-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo …
Matched Iupac: … 5S,6S)-3-{[(3S,5S)-5-(dimethylcarbamoyl)pyrrolidin-3-yl]sulfanyl}-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo …
Matched Description: … Vabomere consists of meropenem and [DB12107] and is intravenously admininstered. ... It is active against Gram-positive and Gram-negative bacteria. ... Meropenem exerts its action by penetrating bacterial cells readily and interfering with the synthesis …
Matched Categories: … meropenem and vaborbactam …
Matched Products: … Meropenem and Sodium Chloride ... Meropenem for Injection USP and Sodium Chloride Injection USP ... Merozan 500mg powder for solution for injection or infusion …
Matched Iupac: … 5S,6S)-3-{[(3S,5S)-5-(dimethylcarbamoyl)pyrrolidin-3-yl]sulfanyl}-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo …
Matched Description: … Vabomere consists of meropenem and [DB12107] and is intravenously admininstered. ... It is active against Gram-positive and Gram-negative bacteria. ... Meropenem exerts its action by penetrating bacterial cells readily and interfering with the synthesis …
Matched Categories: … meropenem and vaborbactam …
Matched Products: … Meropenem and Sodium Chloride ... Meropenem for Injection USP and Sodium Chloride Injection USP ... Merozan 500mg powder for solution for injection or infusion …
5-O-phosphono-alpha-D-ribofuranosyl diphosphate
The key substance in the biosynthesis of histidine, tryptophan, and purine and pyrimidine nucleotides.
Approved
Experimental
Investigational
Matched Synonyms: … 5-O-phosphono-α-D-ribofuranosyl diphosphate …
Matched Name: … 5-O-phosphono-alpha-D-ribofuranosyl diphosphate …
Matched Iupac: … [({[(2R,3R,4S,5R)-3,4-dihydroxy-5-[(phosphonooxy)methyl]oxolan-2-yl]oxy}(hydroxy)phosphoryl)oxy]phosphonic …
Matched Description: … The key substance in the biosynthesis of histidine, tryptophan, and purine and pyrimidine nucleotides …
Matched Name: … 5-O-phosphono-alpha-D-ribofuranosyl diphosphate …
Matched Iupac: … [({[(2R,3R,4S,5R)-3,4-dihydroxy-5-[(phosphonooxy)methyl]oxolan-2-yl]oxy}(hydroxy)phosphoryl)oxy]phosphonic …
Matched Description: … The key substance in the biosynthesis of histidine, tryptophan, and purine and pyrimidine nucleotides …
2,3-Di-O-Sulfo-Alpha-D-Glucopyranose
Experimental
Matched Name: … 2,3-Di-O-Sulfo-Alpha-D-Glucopyranose …
Beta-1,2,3,4,6-Penta-O-Galloyl-D-Glucopyranose
Experimental
Matched Name: … Beta-1,2,3,4,6-Penta-O-Galloyl-D-Glucopyranose …
[4,6-O-(1-CARBOXYETHYLIDENE)-BETA-D-MANNOSE]
Experimental
Matched Name: … [4,6-O-(1-CARBOXYETHYLIDENE)-BETA-D-MANNOSE] …
Fludiazepam
Fludiazepam is a drug which is a benzodiazepine derivative. It possesses anxiolytic, anticonvulsant, sedative and skeletal muscle relaxant properties. It is a scheduled drug in the U.S., but is approved for use in Japan.
Experimental
Illicit
Matched Synonyms: … 7-chloro-5-(o-Fluorophenyl)-1,3-dihydro-1-methyl-2H-1,4-benzodiazepin-2-one …
Matched Iupac: … 7-chloro-5-(2-fluorophenyl)-1-methyl-2,3-dihydro-1H-1,4-benzodiazepin-2-one …
Matched Description: … It possesses anxiolytic, anticonvulsant, sedative and skeletal muscle relaxant properties. …
Matched Categories: … Benzodiazepines and benzodiazepine derivatives …
Matched Iupac: … 7-chloro-5-(2-fluorophenyl)-1-methyl-2,3-dihydro-1H-1,4-benzodiazepin-2-one …
Matched Description: … It possesses anxiolytic, anticonvulsant, sedative and skeletal muscle relaxant properties. …
Matched Categories: … Benzodiazepines and benzodiazepine derivatives …
Canavanine
Experimental
Matched Synonyms: … O-((Aminoiminomethyl)amino)-L-homoserine …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Cyclo(prolylglycyl)
Experimental
Matched Synonyms: … Cyclo(pro-O-gly) …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
cis-tetracosenoyl sulfatide
Experimental
Matched Synonyms: … 1-(3-O-sulfo-beta-D-galactosyl)-N-[(15Z)-tetracos-15-enoyl]sphingosine …
Matched Iupac: … ,3R,4S,5S,6R)-3,5-dihydroxy-2-{[(2S,3R,4E)-3-hydroxy-2-[(15Z)-tetracos-15-enamido]octadec-4-en-1-yl]oxy …
Matched Iupac: … ,3R,4S,5S,6R)-3,5-dihydroxy-2-{[(2S,3R,4E)-3-hydroxy-2-[(15Z)-tetracos-15-enamido]octadec-4-en-1-yl]oxy …
Cefepime
Cefepime is a fourth-generation cephalosporin antibiotic developed in 1994. Cefepime is active against Gram-positive and Gram-negative bacteria, and has greater activity against both compared to third-generation antibiotics.[A2457,A249050] Cefepime is normally used to treat severe nosocomial pneumonia and infections caused by multi-resistant microorganisms such as Pseudomonas aeruginosa, and is also indicated...
Approved
Investigational
Matched Synonyms: … -5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate ... 2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino}-3-[(1-methylpyrrolidinium-1-yl)methyl]-8-oxo …
Matched Iupac: … -1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl}-1-methylpyrrolidin-1-ium ... 1-{[(6R,7R)-7-[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetamido]-2-carboxylato-8-oxo-5-thia …
Matched Description: … The activity of cefepime against Enterobacteriaceae, _Pseudomonas aeruginosa_, and _Staphylococcus aureus ... [A249050] The popularity of its third-generation predecessors, its clinical efficacy, and the high prevalence ... Cefepime is active against Gram-positive and Gram-negative bacteria, and has greater activity against …
Matched Categories: … cefepime and amikacin …
Matched Products: … Cefepime Hydrochloride and Dextrose ... CEFEPIME KABI POWDER FOR SOLUTION FOR INJECTION OR INFUSION 1 g/vial ... CEFEPIME KABI POWDER FOR SOLUTION FOR INJECTION OR INFUSION 2 g/vial …
Matched Iupac: … -1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl}-1-methylpyrrolidin-1-ium ... 1-{[(6R,7R)-7-[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetamido]-2-carboxylato-8-oxo-5-thia …
Matched Description: … The activity of cefepime against Enterobacteriaceae, _Pseudomonas aeruginosa_, and _Staphylococcus aureus ... [A249050] The popularity of its third-generation predecessors, its clinical efficacy, and the high prevalence ... Cefepime is active against Gram-positive and Gram-negative bacteria, and has greater activity against …
Matched Categories: … cefepime and amikacin …
Matched Products: … Cefepime Hydrochloride and Dextrose ... CEFEPIME KABI POWDER FOR SOLUTION FOR INJECTION OR INFUSION 1 g/vial ... CEFEPIME KABI POWDER FOR SOLUTION FOR INJECTION OR INFUSION 2 g/vial …
Magnesium sulfate
A small colorless crystal used as an anticonvulsant, a cathartic, and an electrolyte replenisher in the treatment of pre-eclampsia and eclampsia. It causes direct inhibition of action potentials in myometrial muscle cells. Excitation and contraction are uncoupled, which decreases the frequency and force of contractions. (From AMA Drug Evaluations Annual,...
Approved
Investigational
Vet approved
Matched Description: … treatment of pre-eclampsia and eclampsia. ... Excitation and contraction are uncoupled, which decreases the frequency and force of contractions. ... A small colorless crystal used as an anticonvulsant, a cathartic, and an electrolyte replenisher in the …
Matched Mixtures name: … Tandem OB ... Folivane-OB ... PureFe OB Plus …
Matched Categories: … Alimentary Tract and Metabolism ... Blood and Blood Forming Organs ... Calcium-Regulating Hormones and Agents ... Blood Substitutes and Perfusion Solutions …
Matched Products: … Spearmint and Menthol scented Natural Epsom Salt …
Matched Mixtures name: … Tandem OB ... Folivane-OB ... PureFe OB Plus …
Matched Categories: … Alimentary Tract and Metabolism ... Blood and Blood Forming Organs ... Calcium-Regulating Hormones and Agents ... Blood Substitutes and Perfusion Solutions …
Matched Products: … Spearmint and Menthol scented Natural Epsom Salt …
Heparin
Unfractionated heparin (UH) is a heterogenous preparation of anionic, sulfated glycosaminoglycan polymers with weights ranging from 3000 to 30,000 Da. It is a naturally occurring anticoagulant released from mast cells. It binds reversibly to antithrombin III (ATIII) and greatly accelerates the rate at which ATIII inactivates coagulation enzymes thrombin (factor...
Approved
Investigational
Matched Description: … UH has a higher risk of bleeding and higher risk of osteoporosis in long term use. ... coagulation enzymes thrombin (factor IIa) and factor Xa. ... It binds reversibly to antithrombin III (ATIII) and greatly accelerates the rate at which ATIII inactivates …
Matched Mixtures name: … Heparin Sodium and Dextrose 5% Inj USP ... Heparin Sod and 0.9% Sod Chloride Inj …
Matched Categories: … Heparin and similars ... Blood and Blood Forming Organs ... Heparins or Heparinoids for Topical Use …
Matched Products: … Heparin Sodium and Dextrose ... Heparin Sodium and Sodium Chloride …
Matched Mixtures name: … Heparin Sodium and Dextrose 5% Inj USP ... Heparin Sod and 0.9% Sod Chloride Inj …
Matched Categories: … Heparin and similars ... Blood and Blood Forming Organs ... Heparins or Heparinoids for Topical Use …
Matched Products: … Heparin Sodium and Dextrose ... Heparin Sodium and Sodium Chloride …
RU84687
RU84687 is a subnanomolar and Src SH2 selective binder.
Experimental
Matched Synonyms: … N-acetyl-N-[1-(1,1'-biphenyl-4-ylmethyl)-2-oxoazepan-3-yl]-3-formyl-O-phosphonotyrosinamide …
Matched Description: … RU84687 is a subnanomolar and Src SH2 selective binder. …
Matched Description: … RU84687 is a subnanomolar and Src SH2 selective binder. …
(1R,2R,3S,4R,6S)-4,6-diamino-2-{[3-O-(2,6-diamino-2,6-dideoxy-beta-L-idopyranosyl)-2-O-{2-[(piperidin-3-ylmethyl)amino]ethyl}-beta-D-ribofuranosyl]oxy}-3-hydroxycyclohexyl 2-amino-2-deoxy-alpha-D-glucopyranoside
Experimental
Matched Synonyms: … (1R,2R,3S,4R,6S)-4,6-diamino-2-{[3-O-(2,6-diamino-2,6-dideoxy-β-L-idopyranosyl)-2-O-{2-[(piperidin-3- ... ylmethyl)amino]ethyl}-β-D-ribofuranosyl]oxy}-3-hydroxycyclohexyl 2-amino-2-deoxy-α-D-glucopyranoside …
Matched Name: … (1R,2R,3S,4R,6S)-4,6-diamino-2-{[3-O-(2,6-diamino-2,6-dideoxy-beta-L-idopyranosyl)-2-O-{2-[(piperidin ... -3-ylmethyl)amino]ethyl}-beta-D-ribofuranosyl]oxy}-3-hydroxycyclohexyl 2-amino-2-deoxy-alpha-D-glucopyranoside …
Matched Iupac: … }-5-(hydroxymethyl)-3-(2-{[(piperidin-3-yl)methyl]amino}ethoxy)oxolan-2-yl]oxy}-3-hydroxycyclohexyl]oxy ... )-4,6-diamino-2-{[(2S,3R,4R,5R)-4-{[(2R,3R,4R,5S,6S)-3-amino-6-(aminomethyl)-4,5-dihydroxyoxan-2-yl]oxy …
Matched Name: … (1R,2R,3S,4R,6S)-4,6-diamino-2-{[3-O-(2,6-diamino-2,6-dideoxy-beta-L-idopyranosyl)-2-O-{2-[(piperidin ... -3-ylmethyl)amino]ethyl}-beta-D-ribofuranosyl]oxy}-3-hydroxycyclohexyl 2-amino-2-deoxy-alpha-D-glucopyranoside …
Matched Iupac: … }-5-(hydroxymethyl)-3-(2-{[(piperidin-3-yl)methyl]amino}ethoxy)oxolan-2-yl]oxy}-3-hydroxycyclohexyl]oxy ... )-4,6-diamino-2-{[(2S,3R,4R,5R)-4-{[(2R,3R,4R,5S,6S)-3-amino-6-(aminomethyl)-4,5-dihydroxyoxan-2-yl]oxy …
Amikacin
Amikacin is a semi-synthetic aminoglycoside antibiotic that is derived from kanamycin A.[FDA label] Amikacin is synthesized by acylation with the l-(-)-γ-amino-α-hydroxybutyryl side chain at the C-1 amino group of the deoxystreptamine moiety of kanamycin A. Amikacin's unique property is that it exerts activity against more resistant gram-negative bacilli such as...
Approved
Investigational
Vet approved
Matched Synonyms: … O-3-AMINO-3-DEOXY-.ALPHA.-D-GLUCOPYRANOSYL-(1->4)-O-(6-AMINO-6-DEOXY-.ALPHA. ... D-STREPTAMINE, O-3-AMINO-3-DEOXY-.ALPHA.-D-GLUCOPYRANOSYL-(1->6)-O-(6-AMINO-6-DEOXY-.ALPHA. …
Matched Iupac: … amino-N-[(1R,2S,3S,4R,5S)-5-amino-2-{[(2S,3R,4S,5S,6R)-4-amino-3,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy ... }-4-{[(2R,3R,4S,5S,6R)-6-(aminomethyl)-3,4,5-trihydroxyoxan-2-yl]oxy}-3-hydroxycyclohexyl]-2-hydroxybutanamide …
Matched Description: … of breath and the coughing up of blood. ... M. avium-intracellulare (MAC) is a type of nontuberculous mycobacteria (NTM) found in water and soil. ... Symptoms of this disease include a persistent cough, fatigue, weight loss, night sweats, and shortness …
Matched Categories: … cefepime and amikacin …
Matched Iupac: … amino-N-[(1R,2S,3S,4R,5S)-5-amino-2-{[(2S,3R,4S,5S,6R)-4-amino-3,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy ... }-4-{[(2R,3R,4S,5S,6R)-6-(aminomethyl)-3,4,5-trihydroxyoxan-2-yl]oxy}-3-hydroxycyclohexyl]-2-hydroxybutanamide …
Matched Description: … of breath and the coughing up of blood. ... M. avium-intracellulare (MAC) is a type of nontuberculous mycobacteria (NTM) found in water and soil. ... Symptoms of this disease include a persistent cough, fatigue, weight loss, night sweats, and shortness …
Matched Categories: … cefepime and amikacin …
Mitotane
Mitotane is an adrenolytic isomer of the insecticide dichlorodiphenyldichloroethane (DDD) - itself a metabolite of dichlorodiphenyltrichloroethane (DDT) - that inhibits cells of the adrenal cortex and their production of hormones. It has been in use since 1959 for the treatment of inoperable adrenocortical carcinoma and is used off-label for the...
Approved
Matched Synonyms: … o,p'-DDD …
Matched Description: … metabolite of dichlorodiphenyltrichloroethane (DDT) - that inhibits cells of the adrenal cortex and their ... It has been in use since 1959 for the treatment of inoperable adrenocortical carcinoma[A263010] and is ... used off-label for the management of Cushing's syndrome. …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Description: … metabolite of dichlorodiphenyltrichloroethane (DDT) - that inhibits cells of the adrenal cortex and their ... It has been in use since 1959 for the treatment of inoperable adrenocortical carcinoma[A263010] and is ... used off-label for the management of Cushing's syndrome. …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
WP-1122
WP-1122 is a prodrug of 2-deoxy-D-glucose (2-DG). It was granted FDA orphan designation for the treatment of glioblastoma multiforme.
Investigational
Matched Synonyms: … 3,6-di-O-acetyl-2-deoxy-D-glucopyranose ... an acetic acid diester of 2-deoxy-D-glucose …
Matched Description: … WP-1122 is a prodrug of 2-deoxy-D-glucose (2-DG). ... It was granted FDA orphan designation for the treatment of glioblastoma multiforme.[L47361] …
Matched Description: … WP-1122 is a prodrug of 2-deoxy-D-glucose (2-DG). ... It was granted FDA orphan designation for the treatment of glioblastoma multiforme.[L47361] …
3-FLUORO-4-HYDROXYBENZALDEHYDE O-(CYCLOHEXYLCARBONYL)OXIME
Experimental
Matched Name: … 3-FLUORO-4-HYDROXYBENZALDEHYDE O-(CYCLOHEXYLCARBONYL)OXIME …
Cefixime
Bacteria possess a cell wall comprising a glycopeptide polymer commonly known as peptidoglycan, which is synthesized and remodelled through the action of a family of enzymes known as "penicillin-binding proteins" (PBPs). β-lactam antibiotics, including cephalosporins, are PBP inhibitors that, through inhibition of essential PBPs, result in impaired cell wall homeostasis,...
Approved
Investigational
Matched International brands: … Omnatax-O …
Matched Iupac: … -1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid ... (6R,7R)-7-[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-[(carboxymethoxy)imino]acetamido]-3-ethenyl-8-oxo-5-thia …
Matched Description: … essential PBPs, result in impaired cell wall homeostasis, loss of cell integrity, and ultimately bacterial ... [A262995] Examples of third-generation cephalosporins are [ceftriaxone], [cefotaxime], and [ceftazidime ... , and meningitis. …
Matched Categories: … cefixime and ornidazole ... cefixime and azithromycin …
Matched Products: … FIXACEP OD ... TAXOCEF-O-200MG TABLET ... TAXOCEF-O-400MG TABLET …
Matched Iupac: … -1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid ... (6R,7R)-7-[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-[(carboxymethoxy)imino]acetamido]-3-ethenyl-8-oxo-5-thia …
Matched Description: … essential PBPs, result in impaired cell wall homeostasis, loss of cell integrity, and ultimately bacterial ... [A262995] Examples of third-generation cephalosporins are [ceftriaxone], [cefotaxime], and [ceftazidime ... , and meningitis. …
Matched Categories: … cefixime and ornidazole ... cefixime and azithromycin …
Matched Products: … FIXACEP OD ... TAXOCEF-O-200MG TABLET ... TAXOCEF-O-400MG TABLET …
Displaying drugs 526 - 550 of 710 in total