Displaying drugs 5826 - 5850 of 8297 in total
Ditiocarb
A chelating agent that has been used to mobilize toxic metals from the tissues of man and experimental animals. It is the main metabolite of DISULFIRAM.
Experimental
Matched Description: … It is the main metabolite of DISULFIRAM. ... A chelating agent that has been used to mobilize toxic metals from the tissues of man and experimental …
Amonafide
Amonafide is a substance that is being studied in the treatment of cancer. It belongs to the families of drugs called topoisomerase inhibitors and intercalating agents.
Investigational
Matched Description: … Amonafide is a substance that is being studied in the treatment of cancer. ... It belongs to the families of drugs called topoisomerase inhibitors and intercalating agents. …
Theanine
Theanine, a precursor of ethylamine, is found in green tea. It is under investigation in clinical trial NCT00291070 (Effects of L-Theanine in Boys With ADHD).
Investigational
Matched Description: … Theanine, a precursor of ethylamine, is found in green tea. ... It is under investigation in clinical trial NCT00291070 (Effects of L-Theanine in Boys With ADHD). …
Setrusumab
Setrusumab is under investigation in clinical trial NCT01406548 (Safety and Efficacy of Multiple Dosing Regimens of BPS804 in Post Menopausal Women With Low Bone Mineral Density).
Investigational
Matched Description: … Regimens of BPS804 in Post Menopausal Women With Low Bone Mineral Density). ... Setrusumab is under investigation in clinical trial NCT01406548 (Safety and Efficacy of Multiple Dosing …
Vofatamab
Vofatamab is under investigation in clinical trial NCT02401542 (Dose Escalation, Expansion Study of Vofatamab (B-701) in Treatment of Locally Advanced or Metastatic Urothelial Cell Carcinoma).
Investigational
Matched Description: … (B-701) in Treatment of Locally Advanced or Metastatic Urothelial Cell Carcinoma). ... Vofatamab is under investigation in clinical trial NCT02401542 (Dose Escalation, Expansion Study of Vofatamab …
Dubermatinib
Dubermatinib is under investigation in clinical trial NCT03572634 (Phase 1/2 Study of TP-0903 (an Inhibitor of AXL Kinase) in Patients With Previously Treated CLL).
Investigational
Matched Description: … of AXL Kinase) in Patients With Previously Treated CLL). ... Dubermatinib is under investigation in clinical trial NCT03572634 (Phase 1/2 Study of TP-0903 (an Inhibitor …
Imalumab
Imalumab is under investigation in clinical trial NCT02540356 (Phase 1/2a Two-arm Dose-escalation Study of BAX69 in Subjects With Malignant Ascites of Ovarian Cancer).
Investigational
Matched Description: … BAX69 in Subjects With Malignant Ascites of Ovarian Cancer). ... Imalumab is under investigation in clinical trial NCT02540356 (Phase 1/2a Two-arm Dose-escalation Study of …
Milciclib Maleate
Milciclib Maleate is under investigation in clinical trial NCT01301391 (Study of Oral PHA-848125AC in Patients With Malignant Thymoma Previously Treated With Multiple Lines of Chemotherapy).
Investigational
Matched Description: … Patients With Malignant Thymoma Previously Treated With Multiple Lines of Chemotherapy). ... Milciclib Maleate is under investigation in clinical trial NCT01301391 (Study of Oral PHA-848125AC in …
Pegcantratinib
Pegcantratinib is under investigation in clinical trial NCT03448081 (Safety, Tolerability and Efficacy of SNA-120 for Treatment of Pruritus and Psoriasis in Subjects Treated With Calcipotriene).
Investigational
Matched Description: … SNA-120 for Treatment of Pruritus and Psoriasis in Subjects Treated With Calcipotriene). ... Pegcantratinib is under investigation in clinical trial NCT03448081 (Safety, Tolerability and Efficacy of …
HSK-3486
HSK-3486 is under investigation in clinical trial NCT04620031 (A Study Evaluating Sedation of Intravenous Administration of HSK3486 Injectable Emulsion in ICU Patients Undergoing Mechanical Ventilation).
Investigational
Matched Description: … Administration of HSK3486 Injectable Emulsion in ICU Patients Undergoing Mechanical Ventilation). ... HSK-3486 is under investigation in clinical trial NCT04620031 (A Study Evaluating Sedation of Intravenous …
Letaplimab
Letaplimab is under investigation in clinical trial NCT04485052 (Efficacy and Safety Evaluation of IBI188 in Combination With Azacitidine in Treatment of Patients With Acute Myeloid Leukemia).
Investigational
Matched Description: … in Combination With Azacitidine in Treatment of Patients With Acute Myeloid Leukemia). ... Letaplimab is under investigation in clinical trial NCT04485052 (Efficacy and Safety Evaluation of IBI188 …
Reltecimod
Reltecimod is under investigation in clinical trial NCT02469857 (Phase III Efficacy and Safety Study of AB103 in the Treatment of Patients With Necrotizing Soft Tissue Infections).
Investigational
Matched Description: … AB103 in the Treatment of Patients With Necrotizing Soft Tissue Infections). ... Reltecimod is under investigation in clinical trial NCT02469857 (Phase III Efficacy and Safety Study of …
AS1409
AS1409 is a genetically engineered fusion protein made up of two distinct components. One is the cytokine IL12, which has anti-cancer activity. The other is an antibody that targets tumours. It is developed by Antisoma is in a phase I of clinical trial for the treatment of renal cancer and...
Investigational
Matched Description: … It is developed by Antisoma is in a phase I of clinical trial for the treatment of renal cancer and melanoma ... AS1409 is a genetically engineered fusion protein made up of two distinct components. …
CIGB-258 peptide
CIGB-258 is a peptide that is immunoregulatory and derived from heat shock protein 60 of the cellular variant. As of 2020, The Center for Genetic Engineering and Biotechnology (CIGB) in Havana, Cuba, is testing the treatment efficacy of this peptide in patients with COVID-19 who are under intensive therapy regimens...
Investigational
Matched Description: … CIGB-258 is a peptide that is immunoregulatory and derived from heat shock protein 60 of the cellular ... As of 2020, The Center for Genetic Engineering and Biotechnology (CIGB) in Havana, Cuba, is testing the ... treatment efficacy of this peptide in patients with COVID-19 who are under intensive therapy regimens …
Human Embryonic Stem Cell-derived M Cell
CAStem is composed of immunity- and matrix-regulatory cells (IMRCs), also known as M cells, which can be administered through injection. These IMRCs are differentiated from human embryonic stem cells that are expanded and then harvested. These cells are currently being investigated against lung injury and fibrosis -- conditions which are...
Investigational
Matched Description: … CAStem is composed of immunity- and matrix-regulatory cells (IMRCs), also known as M cells, which can ... are currently being investigated against lung injury and fibrosis -- conditions which are outcomes of ... IMRCs are similar to MSCs in terms of their capacity for self-renewal and tri-lineage differentiation …
TAS-102
TAS-102 (Taiho Pharma USA, Inc.) is an anti-cancer drug under development and in stage 3 clinical trials for the treatment of colorectal cancer. It is composed of the thymidine phosphorylase inhibitor (TPI) tipiracil and the cytotoxin trifluridine. Trifluridine inhibits tumor growth by being incorporated into DNA during DNA synthesis. Tipiracil...
Investigational
Matched Description: … USA, Inc.) is an anti-cancer drug under development and in stage 3 clinical trials for the treatment of ... It is composed of the thymidine phosphorylase inhibitor (TPI) tipiracil and the cytotoxin trifluridine …
Malacidin A
Malacidin A, along with DB14052, is a member of a class of chemicals made by bacteria found in soil that can kill Gram-positive bacteria . Malacidins are 10-member macrocycle lipopeptides discovered via gene sequencing and bioinformatic analysis. While structurally similar to other macrocycle drugs like DB00080 and DB06087, Malacidin A...
Experimental
Matched Description: … Malacidin A, along with [DB14052], is a member of a class of chemicals made by bacteria found in soil …
Malacidin B
Malacidin B, along with DB14051, is a member of a class of chemicals made by bacteria found in soil that can kill Gram-positive bacteria . Malacidins are 10-member macrocycle lipopeptides discovered via gene sequencing and bioinformatic analysis. While structurally similar to other macrocycle drugs like DB00080 and DB06087, Malacidin B...
Experimental
Matched Description: … Malacidin B, along with [DB14051], is a member of a class of chemicals made by bacteria found in soil …
Valinomycin
A cyclododecadepsipeptide ionophore antibiotic produced by Streptomyces fulvissimus and related to the enniatins. It is composed of 3 moles each of L-valine, D-alpha-hydroxyisovaleric acid, D-valine, and L-lactic acid linked alternately to form a 36-membered ring. (From Merck Index, 11th ed) Valinomycin is a potassium selective ionophore and is commonly used...
Experimental
Matched Description: … It is composed of 3 moles each of L-valine, D-alpha-hydroxyisovaleric acid, D-valine, and L-lactic acid …
CVnCoV
The CVnCov Vaccine (or CV07050101) is in development by CureVac AG. The vaccine uses mRNA technology to create a protein associated with SARS-CoV2, and upon administration and replication, to initiate subsequent immune responses in the body. As of June 2020, the company received regulatory approval from German and Belgian Authorities...
Investigational
Matched Description: … Phase 1 clinical trials of this vaccine (NCT04449276). ... As of June 2020, the company received regulatory approval from German and Belgian Authorities to commence …
Etryptamine
In the 1960's, alpha-ethyltryptamine (αET), a non hydrazine reversible monoamine oxidase inhibitor, was developed in the United States by the Upjohn chemical company for use as an antidepressant. αET was an FDA approved antidepressant under the name Monase. However, in 1962, after the discovery of an unacceptable incidence of agranulocytosis,...
Illicit
Investigational
Withdrawn
Matched Description: … However, in 1962, after the discovery of an unacceptable incidence of agranulocytosis, the development ... In 1993, the US Drug Enforcement Administration added αET to Schedule I of its Schedules of Controlled ... of Monase was halted and the drug was withdrawn from potential market use. …
PA-1050040
PA1050040, a second generation HIV-1 maturation inhibitor, is a chemical analog of Bevirimat (BVM). It inhibits virus replication by the same mechanism of action as BVM.
Investigational
Matched Description: … It inhibits virus replication by the same mechanism of action as BVM. ... PA1050040, a second generation HIV-1 maturation inhibitor, is a chemical analog of Bevirimat (BVM). …
PF-04418948
Pf 04418948 is under investigation in clinical trial NCT01002963 (A Study To Investigate The Safety And Toleration Of A Single Dose Of PF-04418948 In Healthy Volunteers).
Investigational
Matched Description: … A Single Dose Of PF-04418948 In Healthy Volunteers). ... under investigation in clinical trial NCT01002963 (A Study To Investigate The Safety And Toleration Of …
Selatogrel
Selatogrel is under investigation in clinical trial NCT03814200 (A Study to Investigate the Effect of Rifampicin on the Uptake and Breakdown of ACT-246475 in Healthy Subjects).
Investigational
Matched Description: … Rifampicin on the Uptake and Breakdown of ACT-246475 in Healthy Subjects). ... Selatogrel is under investigation in clinical trial NCT03814200 (A Study to Investigate the Effect of …
Paltusotine
Paltusotine is under investigation in clinical trial NCT04261712 (A Study to Evaluate the Long-term Safety and Efficacy of Paltusotine for the Treatment of Acromegaly (ACROBAT Advance)).
Investigational
Matched Description: … Paltusotine for the Treatment of Acromegaly (ACROBAT Advance)). ... investigation in clinical trial NCT04261712 (A Study to Evaluate the Long-term Safety and Efficacy of …
Displaying drugs 5826 - 5850 of 8297 in total