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Displaying drugs 6051 - 6075 of 7326 in total
Safrazine is a member of the hydrazine family with non-selective and irreversible inhibitor effects against monoamine oxidases. In 1960, it was used as an antidepressant but it is now discontinued.
Withdrawn
Matched Iupac: … [4-(2H-1,3-benzodioxol-5-yl)butan-2-yl]hydrazine …
Chlorsulfaquinoxaline has been used in trials studying the treatment of Lung Cancer and Colorectal Cancer.
Investigational
Matched Iupac: … 4-amino-N-(5-chloroquinoxalin-2-yl)benzene-1-sulfonamide …
Experimental
Matched Iupac: … 2-(ethylamino)-5-phenyl-4,5-dihydro-1,3-oxazol-4-one …
Experimental
Matched Iupac: … 5-azanidyl-3-(morpholin-4-yl)-1,2,3lambda5-oxadiazol-3-ylium …
Experimental
Matched Iupac: … 5-(heptan-3-yl)-3-[(trichloromethyl)sulfanyl]imidazolidine-2,4-dione …
Experimental
Matched Iupac: … 5-bromo-2-phenyl-2,3-dihydro-1H-indene-1,3-dione …
Experimental
Matched Iupac: … 1-(5-nitro-1,3-thiazol-2-yl)imidazolidin-2-one …
Experimental
Matched Iupac: … N-[2-(dibutylamino)ethyl]-3-phenyl-1,2,4-oxadiazol-5-amine …
Experimental
Matched Iupac: … (2S)-2-amino-5-carbamimidamidopentanoic acid; (2S)-2-aminobutanedioic acid …
Efavaleukin alfa is a fusion protein consisting of interleukin mutein fused to the C-terminus of an immunoglobulin G Fc domain by way of a G4S linker. It is under investigation in clinical trial NCT03422627 (Safety and Efficacy of AMG 592 in Subjects With Steroid Refractory Chronic Graft Versus Host Disease).
Investigational
Investigational
Experimental
Illicit
Matched Iupac: … [1-(2H-1,3-benzodioxol-5-yl)propan-2-yl](ethyl)amine …
Experimental
Matched Iupac: … {[(2R,3S,4R,5S)-5-amino-2,3,4,6-tetrahydroxyhexyl]oxy}phosphonic acid …
Carnosine has been investigated for the treatment of Gulf War Illness.
Investigational
Matched Iupac: … (2S)-2-(3-aminopropanamido)-3-(1H-imidazol-5-yl)propanoic acid …
Vixotrigine has been investigated for the treatment of Bipolar Disorder and Bipolar Depression.
Investigational
Matched Iupac: … (2S,5R)-5-{4-[(2-fluorophenyl)methoxy]phenyl}pyrrolidine-2-carboxamide …
Experimental
Matched Iupac: … (2S)-2-amino-5-carbamimidamidopentanoic acid; 1,3-thiazolidine-2,4-dicarboxylic acid …
Experimental
Matched Iupac: … 5-{[3,5-dimethoxy-4-(2-methoxyethoxy)phenyl]methyl}pyrimidine-2,4-diamine …
Experimental
Matched Iupac: … N-{[(2S)-1-ethylpyrrolidin-2-yl]methyl}-2-methoxy-5-sulfamoylbenzamide …
Experimental
Matched Iupac: … -tetrazol-5-yl)butanoic acid ... (2S)-2-{[4-(2-{2-amino-4-oxo-1H,4H,7H-pyrrolo[2,3-d]pyrimidin-5-yl}ethyl)phenyl]formamido}-4-(2H-1,2,3,4 …
MB07803 is a second generation gluconeogenesis inhibitor for the treatment of type 2 diabetes. It is designed to block the metabolic pathway in the liver that is responsible for producing glucose.
Investigational
Matched Iupac: … ethyl 2-[({5-[2-amino-5-(2,2-dimethylpropanoyl)-1,3-thiazol-4-yl]furan-2-yl}[(1-ethoxy-2-methyl-1-oxopropan …
CS-917 is a novel inhibitor of fructose 1,6-bisphphosphatase (FBPase) which is one of the rate-limiting enzymes of gluconeogenesis.
Investigational
Matched Iupac: … ethyl (2S)-2-[({5-[2-amino-5-(2-methylpropyl)-1,3-thiazol-4-yl]furan-2-yl}({[(2S)-1-ethoxy-1-oxopropan …
GLPG-0259 is under investigation in clinical trial NCT01024517 (GLPG0259 Solid Formulation Bioavailability and Food Effect).
Investigational
Matched Iupac: … -a]pyrazin-5-yl]furan-2-carboxamide ... 4-[8-({4-[(1S,4S)-5-(propan-2-yl)-2,5-diazabicyclo[2.2.1]heptan-2-yl]phenyl}amino)-[1,2,4]triazolo[1,5 …
Olinciguat is under investigation in clinical trial NCT03892499 (A Trial to Evaluate the Effect of Itraconazole (ITZ), a CYP3A4 Inhibitor, on the Pharmacokinetics of the Soluble Guanylate Cyclase Stimulator, Olinciguat (IW-1701), in Healthy Volunteers).
Investigational
Matched Iupac: … (2R)-3-[(5-fluoro-2-{1-[(2-fluorophenyl)methyl]-5-(1,2-oxazol-3-yl)-1H-pyrazol-3-yl}pyrimidin-4-yl)amino …
Narasin is an agent with coccidiostatic and antibacterial properties.
Experimental
Vet approved
Matched Iupac: … (2R)-2-[(2R,3S,5S,6R)-6-[(2S,3S,4S,6R)-6-[(2S,5S,7R,9S,10S,12R,15R)-2-[(2R,5R,6S)-5-ethyl-5-hydroxy-6 ... ]-3-hydroxy-4-methyl-5-oxooctan-2-yl]-3,5-dimethyloxan-2-yl]butanoic acid ... -methyloxan-2-yl]-15-hydroxy-2,10,12-trimethyl-1,6,8-trioxadispiro[4.1.5^{7}.3^{5}]pentadec-13-en-9-yl …
Displaying drugs 6051 - 6075 of 7326 in total