Displaying drugs 6126 - 6150 of 8178 in total
Selgantolimod
Selgantolimod is under investigation in clinical trial NCT03491553 (Safety, Tolerability and Antiviral Activity of Selgantolimod in Virally-suppressed Adults With Chronic Hepatitis B).
Investigational
Matched Description: … Selgantolimod is under investigation in clinical trial NCT03491553 (Safety, Tolerability and Antiviral Activity of …
Taniborbactam
Taniborbactam is under investigation in clinical trial NCT03840148 (Safety and Efficacy Study of Cefepime/vnrx-5133 in Patients With Complicated Urinary Tract Infections).
Investigational
Matched Description: … Taniborbactam is under investigation in clinical trial NCT03840148 (Safety and Efficacy Study of Cefepime …
Imsidolimab
Imsidolimab is under investigation in clinical trial NCT03633396 (A Study to Evaluate the Efficacy and Safety of ANB019 in Subjects With Palmoplantar Pustulosis).
Investigational
Matched Description: … Imsidolimab is under investigation in clinical trial NCT03633396 (A Study to Evaluate the Efficacy and Safety of …
AL-034
AL-034 (TQ-A3334) is an oral toll-like receptor 7 agonist developed for the treatment of chronic hepatitis B (CHB) viral infection.
Investigational
Matched Description: … AL-034 (TQ-A3334) is an oral toll-like receptor 7 agonist developed for the treatment of chronic hepatitis …
BAX 335
BAX 335 is an adeno-associated virus vector 8 (AAV8)–based FIX gene therapy being investigated for the treatment of hemophilia B.
Investigational
Matched Description: … adeno-associated virus vector 8 (AAV8)–based FIX gene therapy being investigated for the treatment of …
ATA-100
ATA-100 is an adeno-associated virus serotype 9 carrying the human Fukutin-Related protein gene and target sequence of the miR-208a
Investigational
Matched Description: … adeno-associated virus serotype 9 carrying the human Fukutin-Related protein gene and target sequence of …
MBP134
MBP134 is a pan-ebolavirus cocktail comprising two broadly neutralizing human antibodies. It is under investigation for the treatment of Sudan ebolavirus (SUDV).
Investigational
Matched Description: … It is under investigation for the treatment of Sudan ebolavirus (SUDV). …
Deuruxolitinib
Deuruxolitinib is under investigation in clinical trial NCT03898479 (Extension Study to Evaluate Safety and Efficacy of CTP-543 in Adults With Alopecia Areata).
Investigational
Matched Description: … under investigation in clinical trial NCT03898479 (Extension Study to Evaluate Safety and Efficacy of …
Bexicaserin
Bexicaserin is under investigation in clinical trial NCT05626634 (Open-label, Long-term Safety Study of LP352 in Subjects With Developmental and Epileptic Encephalopathy).
Investigational
Matched Description: … Bexicaserin is under investigation in clinical trial NCT05626634 (Open-label, Long-term Safety Study of …
N-(2-Aminoethyl)-1-aziridineethanamine
First described in the literature in 2004, N-(2-Aminoethyl)-1-aziridineethanamine is an experimental angiotensin converting enzyme 2 inhibitor investigated for its use in treating cardiovascular disease and its activity against Severe Acute Respiratory Syndrome (SARS).
Experimental
Cloxazolam
Cloxazolam is a benzodiazepine with anxiolytic, sedative/hypnotic, muscle relaxant, and antiepileptic effects. It is marketed in the Argentina, Australia, Portugal, Belgium, Switzerland, Luxembourg, Germany, Taiwan and Japan -- mainly for anti-anxiety. The usual dose of cloxazolam in adults is 3-12mg/day for anti-anxiety. Although less commonly noted, it has also been...
Experimental
Matched Description: … As well, it has also been studied in Japan in doses of 15-30mg/day as an adjunct in the treatment of ... The usual dose of cloxazolam in adults is 3-12mg/day for anti-anxiety. ... Although less commonly noted, it has also been reported as clinically effective in the treatment of depression …
MVA-BN-brachyury-TRICOM vaccine
MVA-BN-brachyury-TRICOM vaccine is an investigational cancer vaccine. It is composed of recombinant vaccinia viral vector, modified vaccinia Ankara-Bavarian Nordic (MVA-BN), encoding the human transcription factor and tumour-associated antigen (TAA) brachyury, and a triad of T-cell co-stimulatory molecules (TRICOM), which is comprised of the three human immune-enhancing co-stimulatory molecules B7-1, ICAM-1...
Investigational
Matched Description: … It is composed of recombinant vaccinia viral vector, modified vaccinia Ankara-Bavarian Nordic (MVA-BN ... encoding the human transcription factor and tumour-associated antigen (TAA) brachyury, and a triad of ... MVA-BN-brachyury-TRICOM vaccine is administered as a priming vaccine, followed by the administration of …
Tifuvirtide
Tifuvirtide is the first members of a new class of anti-HIV drugs which is also called fusion inhibitors. It has received fast-track designation from the FDA and is in Phase I/II clinical testing.
Investigational
Matched Description: … Tifuvirtide is the first members of a new class of anti-HIV drugs which is also called fusion inhibitors …
99mTc-14 F7 Mab
99mTc 14F7 Mab has strong anti tumor activity against myeloma cells in vivo. Growth inhibition and prolonged survival of the myeloma tumor were obtained as evidences of anti tumor effect after treatment with 99mTc 14F7 Mab.
Investigational
Matched Description: … Growth inhibition and prolonged survival of the myeloma tumor were obtained as evidences of anti tumor …
Atrasentan
Atrasentan is a substance that is being studied in the treatment of cancer. It belongs to the family of drugs called endothelin-1 protein receptor antagonists. It is a novel, selective endothelin A receptor antagonist (SERA).
Investigational
Matched Description: … Atrasentan is a substance that is being studied in the treatment of cancer. ... It belongs to the family of drugs called endothelin-1 protein receptor antagonists. …
Bifunctional epoxide hydrolase 2
Bifunctional epoxide hydrolase 2 is under investigation in clinical trial NCT00654966 (Evaluation of the Effects of Urotensin-II and Soluble Epoxide Hydrolase Inhibitors on Skin Microvessel Tone in Patients With Heart Failure, and in Healthy Volunteers).
Investigational
Matched Description: … Bifunctional epoxide hydrolase 2 is under investigation in clinical trial NCT00654966 (Evaluation of ... the Effects of Urotensin-II and Soluble Epoxide Hydrolase Inhibitors on Skin Microvessel Tone in Patients …
Itepekimab
Itepekimab is under investigation in clinical trial NCT03546907 (Proof-of-concept Study to Assess the Efficacy, Safety and Tolerability of SAR440340 (Anti-il-33 Mab) in Patients With Moderate-to-severe Chronic Obstructive Pulmonary Disease (COPD)).
Investigational
Matched Description: … Itepekimab is under investigation in clinical trial NCT03546907 (Proof-of-concept Study to Assess the ... Efficacy, Safety and Tolerability of SAR440340 (Anti-il-33 Mab) in Patients With Moderate-to-severe …
Prasterone sulfate
DHEA sulfate is the major steroid of the fetal adrenal. DHEA-S is the principal adrenal androgen and is secreted together with cortisol under the control of ACTH and prolactin. DHEA-S is elevated with hyperprolactinemia.
Investigational
Matched Description: … DHEA sulfate is the major steroid of the fetal adrenal. ... DHEA-S is the principal adrenal androgen and is secreted together with cortisol under the control of …
Ifenprodil
N-methyl-D-aspartate (NMDA) receptors (NMDARs) are members of the ionotropic glutamate receptor family, with key roles in brain development and neurological function.[A220118, A220128] NMDARs are heterotetramers that typically involve a dimer of dimers of both GluN1 and GluN2A-D subunits, with each subunit itself composed of an N-terminal domain (NTD), a ligand-binding...
Investigational
Withdrawn
Matched Description: … [A220118, A220128] NMDARs are heterotetramers that typically involve a dimer of dimers of both GluN1 ... Binding at the LBD of the agonists glycine (or D-serine) to the GluN1 subunits and of glutamate to the ... N-methyl-D-aspartate (NMDA) receptors (NMDARs) are members of the ionotropic glutamate receptor family …
SARS-CoV-2 mRNA vaccine
SARS-CoV-2 mRNA vaccine (ARCoV) is a novel mRNA coronavirus vaccine that consists of a lipid nanoparticle-encapsulated mRNA encoding the receptor binding domain of SARS-CoV-2 . It is the first COVID-19 mRNA vaccine to be approved for clinical trials in China, and was co-developed by Abogen Biosciences, Walvax Biotechnolgoy Co., Ltd....
Investigational
Matched Description: … mRNA encoding the receptor binding domain of SARS-CoV-2[A220048]. ... by Abogen Biosciences, Walvax Biotechnolgoy Co., Ltd. and the People’s Liberation Army (PLA) Academy of ... Preclinical studies in mice and non-human primates has shown that intramuscular administration of ARCoV …
Acepromazine
Acepromazine is one of the phenothiazine derivative psychotropic drugs, used little in humans, however frequently in animals as a sedative and antiemetic.
Experimental
Vet approved
Matched Description: … Acepromazine is one of the phenothiazine derivative psychotropic drugs, used little in humans, however …
Phenacetin
Phenacetin was withdrawn from the Canadian market in June 1973 due to concerns regarding nephropathy (damage to or disease of the kidney).
Withdrawn
Matched Description: … withdrawn from the Canadian market in June 1973 due to concerns regarding nephropathy (damage to or disease of …
REP8839
REP8839 is a novel methionyl-tRNA synthetase (MetS) inhibitor being developed by Replidyne (GlaxoSmithKline licensed REP8839 to Replidyne in June of 2003).
Investigational
Matched Description: … MetS) inhibitor being developed by Replidyne (GlaxoSmithKline licensed REP8839 to Replidyne in June of …
MAHDL01
MAHDL01 is a pharmaceutical combination of whole plants, which is used to increase the HDL/LDL ratio that improves overall cardiovascular health.
Investigational
Matched Description: … MAHDL01 is a pharmaceutical combination of whole plants, which is used to increase the HDL/LDL ratio …
Dactolisib
Dactolisib has been used in trials studying the treatment of Cancer, Solid Tumor, Renal Cancer, Breast Cancer, and Cowden Syndrome, among others.
Investigational
Matched Description: … Dactolisib has been used in trials studying the treatment of Cancer, Solid Tumor, Renal Cancer, Breast …
Displaying drugs 6126 - 6150 of 8178 in total