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Displaying drugs 601 - 625 of 1405 in total
Guanosine 5'-(trihydrogen diphosphate), monoanhydride with phosphorothioic acid. A stable GTP analog which enjoys a variety of physiological actions such as stimulation of guanine nucleotide-binding proteins, phosphoinositide hydrolysis, cyclic AMP accumulation, and activation of specific proto-oncogenes.
Experimental
Matched Synonyms: … GTP gamma S ... gamma-Thio-GTP ... Guanosine 5'-(gamma-S)triphosphate …
Matched Description: … stimulation of guanine nucleotide-binding proteins, phosphoinositide hydrolysis, cyclic AMP accumulation, and
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Alizapride is a dopamine antagonist that is capable of demonstrating both prokinetic and antiemetic effects. This kind of pharmacological activity makes it effective for use in the treatment of various kinds of nausea and vomiting, including that which may occur postoperatively.
Investigational
Matched Description: … Alizapride is a dopamine antagonist that is capable of demonstrating both prokinetic and antiemetic effects ... of pharmacological activity makes it effective for use in the treatment of various kinds of nausea and
Matched Categories: … Alimentary Tract and Metabolism …
Matched Products: … ALIZAPRIDA 12 MG/ML ... ALIPRID SOLUCION ORAL 12 MG/ML ... ALIZAPRIDA 12 MG/ML GOTAS ORALES …
Overactive bladder (OAB) is a common condition negatively impacting the lives of millions of patients worldwide. Due to its urinary symptoms that include nocturia, urgency, and frequency, this condition causes social embarrassment and a poor quality of life.[A185996,A185999] Oxybutynin, also marketed as Ditropan XL, is an anticholinergic medication used for...
Approved
Investigational
Matched Description: … embarrassment and a poor quality of life. ... Due to its urinary symptoms that include nocturia, urgency, and frequency, this condition causes social ... used for the relief of overactive bladder symptoms that has been optimized for high levels of safety and
Matched Salts name: … Oxybutynin chloride
Matched Categories: … Genito Urinary System and Sex Hormones ... Drugs for Urinary Frequency and Incontinence …
Matched Products: … Oxybutynin Chloride ... Pat-oxybutynin Chloride ER ... Oxybutynin Chloride Extended Release …
Cholesteryl chloride, also known as 3-chlorocholest-5-ene, is an organochloride derivative of cholesterol. It is presented as a liquid crystal that forms clockwise liquid crystals.
Experimental
Matched Synonyms: … Cholesterol chloride
Matched Name: … Cholesteryl chloride
Matched Description: … Cholesteryl chloride, also known as 3-chlorocholest-5-ene, is an organochloride derivative of cholesterol …
Zalutumumab is a fully human IgG1 monoclonal antibody designed to bind with selectivity to the epidermal growth factor receptor (EGFR). Zalutumumab has been investigated for the treatment of Squamous Cell Cancer and Head and Neck Cancer.
Investigational
Matched International brands: … HuMax-EGFR ... HuMax-EGFR-2F8 ... HuMax-EGFR, 2F8 …
Matched Description: … Zalutumumab has been investigated for the treatment of Squamous Cell Cancer and Head and Neck Cancer. ... Zalutumumab is a fully human IgG1 monoclonal antibody designed to bind with selectivity to the epidermal …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Astemizole is a long-acting, non-sedating second generation antihistamine used in the treatment of allergy symptoms. It was withdrawn from market by the manufacturer in 1999 due to the potential to cause arrhythmias at high doses, especially when when taken with CYP inhibitors or grapefruit juice.
Approved
Withdrawn
Matched Categories: … Histamine Agents ... Histamine Antagonists ... Histamine H1 Antagonists ... Histamine H1 Antagonists, Non-Sedating …
Matched Products: … HISTAMEN
A benzophenanthridine alkaloid evaluated as a kinase-inhibitor.
Investigational
Matched Synonyms: … (1,3)benzodioxolo(5,6-c)phenanthridinium, 1,2-dimethoxy-12-methyl- ... 1,2-dimethoxy-12-methyl(1,3)dioxolo)4',5':4,5)benzo(1,2-c)phenanthridinium …
Matched Salts name: … Chelerythrine chloride
Rulonilimab is under investigation in clinical trial NCT05408221 (The Efficacy and Safety of Rulonilimab in Combination With Lenvatinib in Hepatocellular Carcinoma).
Investigational
Matched Synonyms: … 1) (human-mus musculus monoclonal f520 .gamma.1-chain), disulfide with human-mus musculus monoclonal ... Immunoglobulin g1 (251-glutamine,298-alanine,429-leucine), anti-(human programmed cell death protein …
Matched Description: … Rulonilimab is under investigation in clinical trial NCT05408221 (The Efficacy and Safety of Rulonilimab …
Radium Ra 223 Dichloride is a radiopharmaceutical containing the radioisotope radium-223 that emits short range but high linear energy alpha particles. As a cation, radium mimics calicum and binds to hydroxyapatite, which is a bone mineral found in areas of high bone turnover as seen in bone metastases. It was...
Approved
Investigational
Matched Synonyms: … Radium chloride Ra-223 ... Radium-223 chloride
Matched Description: … As a cation, radium mimics calicum and binds to hydroxyapatite, which is a bone mineral found in areas ... It was first approved by the FDA in May 2013 and is currently marketed under the brand name Xofigo, which ... indicated in patients who have metastatic bone cancer that is symptomatic with no visceral metastases and
Dequalinium is an antibacterial agent with multi-targeted actions. It also possesses antifungal, antiparasitic, antiviral, anticancer, and neuroprotective properties. It is a quaternary ammonium compound, as it consists of an amphipathic cation with two aminoquinaldinium rings at both ends of a long hydrophobic hydrocarbon chain. Due to its flexible structure, dequalinium...
Approved
Investigational
Matched Synonyms: … Decamethylenebis(4-aminoquinaldinium chloride) ... 1,1'-Decamethylenebis(4-aminoquinaldinium chloride) …
Matched Description: … various OTC products to treat conditions of oral infections and inflammation. ... It also possesses antifungal, antiparasitic, antiviral, anticancer, and neuroprotective properties. ... Due to its flexible structure, dequalinium was investigated to build drug and gene delivery systems. …
Matched Salts name: … Dequalinium chloride
Matched Categories: … Antiseptics and Disinfectants ... Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics …
Furosemide is a potent loop diuretic that acts on the kidneys to ultimately increase water loss from the body. It is an anthranilic acid derivative. Furosemide is used for edema secondary to various clinical conditions, such as congestive heart failure exacerbation, liver failure, renal failure, and high blood pressure. It...
Approved
Vet approved
Matched Description: … Furosemide has a fast onset and short duration of action and has been used safely and effectively in ... both pediatric and adult patients. ... various clinical conditions, such as congestive heart failure exacerbation, liver failure, renal failure, and
Matched Mixtures name: … Diascreen 12-Panel Medicated Collection System …
Matched Categories: … furosemide and potassium ... furosemide and potassium-sparing agents ... High-Ceiling Diuretics and Potassium-Sparing Agents ... Sodium Potassium Chloride Symporter Inhibitors …
Matched Products: … FUROSEMID 125 1A PHARMA ... FUROMID 40 MG TABLET, 12 TABLET ... LIZIK 40 MG TABLET, 12 ADET …
An ethanolamine-derivative, first generation histamine H1 antagonist used in hay fever, rhinitis, allergic skin conditions, and pruritus. It causes drowsiness.
Approved
Investigational
Matched Description: … skin conditions, and pruritus. ... An ethanolamine-derivative, first generation histamine H1 antagonist used in hay fever, rhinitis, allergic …
Matched Categories: … Histamine Agents ... Histamine Antagonists ... Histamine H1 Antagonists …
Matched Products: … Wal Hist 12 Hour Relief ... Dayhist Allergy 12 Hour Relief ... Sunmark 12 Hour Allergy Relief …
Quaternium-15 is a quaternary ammonium salt used as a surfactant and preservative in many products including cosmetics. It is an anti-microbial agent by virtue of being a formaldehyde releaser, however this can also cause contact dermatitis, a symptom of an allergic reaction, especially in those with sensitive skin. In 2005,...
Approved
Experimental
Matched Synonyms: … N-(3-Chloroallyl)hexaminium chloride ... 1-(3-Chloroallyl)-3,5,7-triaza-1-azoniaadamantane chloride ... 3,5,7-Triaza-1-azoniaadamantane, 1-(3-chloroallyl)-, chloride
Matched Iupac: … 1-(3-chloroprop-2-en-1-yl)-1,3,5,7-tetraazatricyclo[3.3.1.1^{3,7}]decan-1-ium chloride
Matched Description: … Quaternium-15 is a quaternary ammonium salt used as a surfactant and preservative in many products including …
Matched Categories: … Increased Histamine Release …
Sonelokimab is under investigation in clinical trial NCT06411379 (Study to Evaluate the Efficacy and Safety of Subcutaneous Sonelokimab Compared With Placebo in Adult Participants With Moderate to Severe Hidradenitis Suppurativa).
Investigational
Matched Synonyms: … M-1095 (anti-interleukin (il)-17a/f single-domain antibody) …
Matched Description: … Sonelokimab is under investigation in clinical trial NCT06411379 (Study to Evaluate the Efficacy and
Matched Categories: … Amino Acids, Peptides, and Proteins …
Nofazinlimab is under investigation in clinical trial NCT04194775 (A Study of Nofazinlimab (CS1003) in Subjects With Advanced Hepatocellular Carcinoma).
Investigational
Matched Synonyms: … cs1003 .gamma.4-chain), disulfide with human-mus musculus monoclonal cs1003 .kappa. ... Immunoglobulin g4 (223-proline), anti-(human programmed cell death protein 1) (human-mus musculus monoclonal …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Cyanocobalamin (commonly known as Vitamin B12) is a highly complex, essential vitamin, owing its name to the fact that it contains the mineral, cobalt. This vitamin is produced naturally by bacteria , and is necessary for DNA synthesis and cellular energy production. Vitamin B12 has many forms, including the cyano-,...
Approved
Nutraceutical
Matched International brands: … Vitabee 12
Matched Description: … This vitamin is produced naturally by bacteria [A175276], and is necessary for DNA synthesis and cellular ... Vitamin B12 has many forms, including the cyano-, methyl-, deoxyadenosyl- and hydroxy-cobalamin forms ... The _cyano_ form, is the most widely used form in supplements and prescription drugs [A175255], [FDA …
Matched Mixtures name: … NATURE'S BOUNTY NATUREL B-COMPLEX AND B-12 TABLET, 90 ADET ... .-12 ... B-12 Kit …
Matched Categories: … Vitamin B 12, biosynthesis ... Diet, Food, and Nutrition ... Blood and Blood Forming Organs ... Vitamin B12 and Folic Acid ... iron, vitamin B12 and folic acid …
Matched Products: … B - 12 ... ยูเมด-บี12 ... วิตามินบี 12
Marstacimab is a human Monoclonal Antibody Directed Against Tissue Factor Pathway Inhibitor currently being developed by Pfizer for the treatment of hemophilia A and hemophilia B.
Investigational
Matched Synonyms: … Immunoglobulin g1, anti-(human tissue factor pathway inhibitor) (human monoclonal pf-06741086 .gamma.1 ... -chain), disulfide with human monoclonal pf-06741086 .lambda. ... Immunoglobulin g1-lambda, anti-(human tissue factor pathway inhibitor (tfpi, extrinsic pathway inhibitor …
Matched Description: … being developed by Pfizer for the treatment of hemophilia A and hemophilia B. ... Marstacimab is a human Monoclonal Antibody Directed Against Tissue Factor Pathway Inhibitor currently …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Cefotaxime is a third-generation cephalosporin antibiotic. Like other third-generation cephalosporins, it has broad spectrum activity against Gram positive and Gram negative bacteria. In most cases, it is considered to be equivalent to ceftriaxone in terms of safety and efficacy. Cefotaxime sodium is marketed under various trade names including Claforan (Sanofi-Aventis).
Approved
Matched Description: … Like other third-generation cephalosporins, it has broad spectrum activity against Gram positive and ... In most cases, it is considered to be equivalent to ceftriaxone in terms of safety and efficacy. …
Matched Products: … Cefotaxime and Dextrose …
Sotigalimab is under investigation in clinical trial NCT03123783 (CD40 Agonistic Antibody APX005M in Combination With Nivolumab).
Investigational
Matched Synonyms: … CUNICULUS MONOCLONAL APX005M .GAMMA.1-CHAIN), DISULFIDE WITH HUMAN-ORYCTOLAGUS CUNICULUS MONOCLONAL ... IMMUNOGLOBULIN G1 (270-GLUTAMIC ACID, C-TERMINAL-LYSINE-CLIPPED), ANTI-(HUMAN CD40 ANTIGEN) (HUMAN-ORYCTOLAGUS …
Matched Categories: … Amino Acids, Peptides, and Proteins …
FB-825 is an investigational humanized monoclonal antibody that targets the CεmX domain of the membrane-bound IgE (mIgE), causing a depletion of mIgE positive B-cells. It is currently being investigated for immune disorders, such as atopic dermatitis and hyperimmunoglobulin E syndrome (HIES).[A258448,L45743]
Investigational
Matched Synonyms: … of human membrane-bound immunoglobulin E (mIgE) ... Recombinant humanized immunoglobulin gamma 1 monoclonal antibody (mAb) directed against the CemX segment …
Matched Description: … It is currently being investigated for immune disorders, such as atopic dermatitis and hyperimmunoglobulin …
Ivonescimab is under investigation in clinical trial NCT05184712 (Phase 3 Clinical Study of AK112 for NSCLC Patients).
Investigational
Matched Synonyms: … MUSCULUS MONOCLONAL AK112 .GAMMA.1-CHAIN) FUSION PROTEIN WITH PEPTIDE LINKER (GGGS)4 FUSION PROTEIN ... IMMUNOGLOBULIN G1 (240-ALANINE,241-ALANINE), ANTI-(HUMAN VASCULAR ENDOTHELIAL GROWTH FACTOR A) (HUMAN-MUS ... WITH IMMUNOGLOBULIN ANTI-(HUMAN PROGRAMMED CELL …
Ponsegromab is under investigation in clinical trial NCT05492500 (A Study of Ponsegromab in People With Heart Failure).
Investigational
Matched Synonyms: … ) (human-mus musculus monoclonal pf-06946860 .gamma.1-chain), disulfide with human-mus musculus monoclonal ... Immunoglobulin g1 (237-alanine,238-alanine,240-alanine), anti-(human growth differentiation factor 15 …
Roxadustat is a first-in-class hypoxia-inducible factor prolyl hydroxylase inhibitor used to treat anemia associated with chronic kidney disease. It works by reducing the breakdown of the hypoxia-inducible factor (HIF), which is a transcription factor that stimulates red blood cell production in response to low oxygen levels. Roxadustat was first approved...
Approved
Investigational
Matched Categories: … Amino Acids, Peptides, and Proteins ... Blood and Blood Forming Organs …
Matched Products: … EVRENZO 20 MG FİLM KAPLI TABLET, 12 ADET ... EVRENZO 50 MG FİLM KAPLI TABLET, 12 ADET ... EVRENZO 70 MG FİLM KAPLI TABLET, 12 ADET …
Investigational
Matched Synonyms: … Immunoglobulin g 1 (mouse monoclonal immu-4 fab' fragment .gamma. ... Immunoglobulin g 1 (mouse monoclonal immu-4 fab' fragment .gamma. ... -chain anti-human antigen cea), disulfide with mouse monoclonal immu-4 light chain …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Experimental
Matched Name: … 12-Bromododecanoic Acid …
Matched Iupac: … 12-bromododecanoic acid …
Displaying drugs 601 - 625 of 1405 in total