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Displaying drugs 601 - 625 of 2505 in total
Dasatinib is an orally available multikinase inhibitor indicated for the treatment of Philadelphia chromosome (Ph)-positive leukemias.[A2224,L45171] Ph is a chromosomal abnormality found in patients with chronic myelogenous leukemia (CML) and acute lymphocytic leukemia (ALL), where the ABL tyrosine kinase and the breakpoint cluster region (BCR) gene transcribe the chimeric protein...
Approved
Investigational
Matched Synonyms: … Anhydrous dasatinib ... Dasatinib anhydrous ... dasatinib (anhydrous) …
Matched Description: … pathogenesis of CML and 15-30% of ALL cases. ... ALL, dasatinib inhibits the active and inactive conformations of the ABL kinase domain. ... acute lymphocytic leukemia (ALL), where the ABL tyrosine kinase and the breakpoint cluster region (BCR …
Matched Salts name: … Dasatinib monohydrate
Matched Categories: … Antineoplastic and Immunomodulating Agents …
A phosphorothioate proposed as a radiation-protective agent. It causes splenic vasodilation and may block autonomic ganglia.
Approved
Investigational
Matched Synonyms: … Amifostine anhydrous
Matched Iupac: … ({2-[(3-aminopropyl)amino]ethyl}sulfanyl)phosphonic acid
Matched Description: … It causes splenic vasodilation and may block autonomic ganglia. …
Radiopaque medium used in the diagnosis of gall bladder & bile duct diseases, usually as meglumine salt.
Experimental
Matched Synonyms: … Iodoxamic acid ... Acidum iodoxamicum …
Matched Name: … Iodoxamic acid
Matched Iupac: … 3-carboxy-2,4,6-triiodophenyl)carbamoyl]-3,6,9,12-tetraoxapentadecan-15-amido}-2,4,6-triiodobenzoic acid
Matched Categories: … Acids, Carbocyclic ... Carboxylic Acids ... iodoxamic acid
Gatifloxacin is an antibiotic agent and a member of the fourth-generation fluoroquinolone family. It works by inhibiting the bacterial enzymes DNA gyrase and topoisomerase IV. It was first introduced by Bristol-Myers Squibb in 1999 under the brand name Tequin® for the treatment of respiratory tract infections. Gatifloxacin is available as...
Approved
Investigational
Withdrawn
Matched Synonyms: … Gatifloxacin anhydrous ... 1-cyclopropyl-6-fluoro- 8-methoxy-7-(3-methylpiperazin-1-yl)- 4-oxo-quinoline-3-carboxylic acid ... 1-Cyclopropyl-1,4-dihydro-6-fluoro-8-methoxy-7-(3-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic acid
Matched Iupac: … 1-cyclopropyl-6-fluoro-8-methoxy-7-(3-methylpiperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid
Matched Description: … It works by inhibiting the bacterial enzymes DNA gyrase and topoisomerase IV. ... Gatifloxacin is an antibiotic agent and a member of the fourth-generation fluoroquinolone family. ... Gatifloxacin is available as tablets and in various aqueous solutions for intravenous therapy. …
Approved
Experimental
Matched Synonyms: … Ferric chloride, anhydrous
Matched Categories: … Acids ... Acids, Noncarboxylic …
Commonly known as decadron, dexamethasone acetate is a glucocorticosteroid previously marketed in the USA for the treatment of inflammatory respiratory, allergic, autoimmune, and other conditions.[T797,L10695,L14348] Developed in 1957, dexamethasone is structurally similar to other corticosteroids such as hydrocortisone and prednisolone. Dexamethasone acetate has largely been replaced by dexamethasone phosphate and...
Approved
Investigational
Vet approved
Matched Synonyms: … Dexamethasone acetate anhydrous ... Dexamethasone acetate, anhydrous
Matched Description: … one-third in patients on oxygen therapy and mechanical ventilation, respectively. ... previously marketed in the USA for the treatment of inflammatory respiratory, allergic, autoimmune, and ... [A188724] Dexamethasone acetate has largely been replaced by [dexamethasone] phosphate and continues …
Lisinopril is an angiotensin converting enzyme inhibitor (ACEI) used to treat hypertension, heart failure, and myocardial infarction.[L8384,L8387,L8390] Lisinopril and captopril are the only ACEIs that are not prodrugs. It functions by inhibition of angiotensin converting enzyme as well as the renin angiotensin aldosterone system.[A184781,A184808,A184817] ACEIs are commonly used as a...
Approved
Investigational
Matched Synonyms: … Lisinopril anhydrous
Matched Iupac: … (2S)-1-[(2S)-6-amino-2-{[(1S)-1-carboxy-3-phenylpropyl]amino}hexanoyl]pyrrolidine-2-carboxylic acid
Matched Description: … [L8384,L8387,L8390] Lisinopril and [captopril] are the only ACEIs that are not prodrugs. ... Lisinopril is an angiotensin converting enzyme inhibitor (ACEI) used to treat hypertension, heart failure, and
Matched Mixtures name: … Lisinopril and Hydrochlorothiazide ... Lisinopril and Hydrochlorothiazide ... Lisinopril and HCTZ …
Matched Salts name: … Lisinopril dihydrate
Matched Categories: … Amino Acids, Peptides, and Proteins ... ACE Inhibitors and Diuretics ... lisinopril and diuretics ... lisinopril and amlodipine ... ACE Inhibitors and Calcium Channel Blockers …
Matched Products: … LISINOPRIL DIHYDRATE
Investigational
Matched Synonyms: … Fumaric acid ... Fumaricum acidum ... (2E)-2-butenedioic acid
Matched Name: … Fumaric acid
Matched Iupac: … (2E)-but-2-enedioic acid
Matched Categories: … Acids, Acyclic ... fumaric acid ... Carboxylic Acids ... Dicarboxylic Acids
Experimental
Matched Synonyms: … acid ... (6R)-5-Acetamido-6-[(1R,2R)-3-amino-1,2-dihydroxypropyl]-2,6-anhydro-3,5-dideoxy-L-threo-hex-2-enonic …
Matched Name: … 9-Amino-2-deoxy-2,3-dehydro-n-acetyl-neuraminic acid
Matched Iupac: … 4S)-2-[(1R,2R)-3-amino-1,2-dihydroxypropyl]-3-acetamido-4-hydroxy-3,4-dihydro-2H-pyran-6-carboxylic acid
Clavulanic acid is a beta-lactamase inhibitor that is frequently combined with Amoxicillin or Ticarcillin to fight antibiotic resistance by preventing their degradation by beta-lactamase enzymes, broadening their spectrum of susceptible bacterial infections. Clavulanic acid is derived from the organism Streptomyces clavuligerus. When it is combined with amoxicillin, clavulanic acid is...
Approved
Vet approved
Matched Synonyms: … Clavulanic acid ... Acide clavulanique ... Acidum clavulanicum …
Matched Name: … Clavulanic acid
Matched Iupac: … (2R,3Z,5R)-3-(2-hydroxyethylidene)-7-oxo-4-oxa-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
Matched Description: … [T665] Clavulanic acid is derived from the organism Streptomyces clavuligerus. ... Clavulanic acid is a beta-lactamase inhibitor that is frequently combined with [Amoxicillin] or [Ticarcillin ... [A182228]When it is combined with amoxicillin, clavulanic acid is frequently known as Augmentin, Co-Amoxiclav …
Matched Mixtures name: … ACIX® ... AMOXICILLINA ACIDO CLAVULANICO TEVA ... AMOXICILLINA ACIDO CLAVULANICO TEVA …
Approved
Vet approved
Matched Mixtures name: … Neomycin and Polymyxin B Sulfates and Bacitracin Zinc with Hydrocortisone Acetate ... Neomycin and Polymyxin B Sulfates and Bacitracin Zinc with Hydrocortisone Acetate ... Neomycin and Polymyxin B Sulfates and Bacitracin Zinc with Hydrocortisone Acetate …
Matched Categories: … Hydrocortisone and derivatives ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … American Safety and First Aid …
Xaluritamig is a novel humanized bispecific T cell recruiting antibody cross-reactive to human and nonhuman primate STEAP1 and CD3.
Investigational
Matched Synonyms: … STEAP family member 1, six transmembrane epithelial antigen of the prostate 1, STEAP1 metalloreductase) and
Matched Description: … primate STEAP1 and CD3. ... Xaluritamig is a novel humanized bispecific T cell recruiting antibody cross-reactive to human and nonhuman …
Long-acting, broad-spectrum, water-soluble, cephalexin derivative.
Approved
Vet approved
Withdrawn
Matched Synonyms: … Cefadroxil anhydrous
Matched Iupac: … amino-2-(4-hydroxyphenyl)acetamido]-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
Matched Salts name: … Cefadroxil monohydrate
Matched Products: … CEFADROXIL MONOHYDRATE
Cupric chloride, for injection, is a sterile, nonpyrogenic solution intended for use as an additive to solutions for Total Parenteral Nutrition (TPN).
Approved
Investigational
Matched Synonyms: … Cupric chloride anhydrous
Matched Salts name: … Cupric chloride dihydrate
Etidronic acid is a first generation bisphosphonate similar to clodronic acid and tiludronic acid. These drugs were developed to mimic the action of pyrophosphate, a regulator of calcification and decalcification. Etidronate’s use has decreased over the years in favor of the third generation, nitrogen containing bisphosphonate zoledronic acid, ibandronic acid,...
Approved
Matched Synonyms: … Etidronic acid ... acide étidronique ... acidum etidronicum …
Matched Name: … Etidronic acid
Matched Iupac: … (1-hydroxy-1-phosphonoethyl)phosphonic acid
Matched Description: … ], [ibandronic acid], [minodronic acid], and [risedronic acid]. ... Etidronic acid is a first generation bisphosphonate similar to [clodronic acid] and [tiludronic acid] ... A203111] These drugs were developed to mimic the action of pyrophosphate, a regulator of calcification and
Matched Categories: … etidronic acid and calcium, sequential ... Drugs Affecting Bone Structure and Mineralization ... etidronic acid
A potent, non-nucleoside reverse transcriptase inhibitor (NNRTI) used in combination with nucleoside analogues for treatment of Human Immunodeficiency Virus Type 1 (HIV-1) infection and AIDS. Structurally, nevirapine belongs to the dipyridodiazepinone chemical class.
Approved
Matched Synonyms: … Nevirapine anhydrous ... Nevirapine, anhydrous
Matched Description: … combination with nucleoside analogues for treatment of Human Immunodeficiency Virus Type 1 (HIV-1) infection and
Matched Mixtures name: … Lamivudine, Nevirapine, and Zidovudine ... LAMIVUDINE, NEVIRAPINE AND ZIDOVUDINE TABLETS (150/200/300 mg) …
Matched Categories: … Nucleic Acid Synthesis Inhibitors ... stavudine, lamivudine and nevirapine ... zidovudine, lamivudine and nevirapine ... Metabolic Side Effects of Drugs and Substances …
Experimental
Matched Synonyms: … Anhydrous chloral …
Coumarin derivative that acts as a long-acting oral anticoagulant.
Approved
Investigational
Matched Categories: … Blood and Blood Forming Organs …
Matched Products: … PHENPROCOUMON ACIS 3MG TAB …
A guanido-neuraminic acid that is used to inhibit neuraminidase.
Approved
Investigational
Matched Synonyms: … 5-acetamido-2,6-anhydro-3,4,5-trideoxy-4-guanidino-D-glycero-D-galacto-non-2-enonic acid ... 5-(acetylamino)-2,6-anhydro-4-carbamimidamido-3,4,5-trideoxy-D-glycero-D-galacto-non-2-enonic acid ... 4-guanidino-2,4-dideoxy-2,3-dehydro-N-acetylneuraminic acid
Matched Iupac: … diaminomethylidene)amino]-3-acetamido-2-[(1R,2R)-1,2,3-trihydroxypropyl]-3,4-dihydro-2H-pyran-6-carboxylic acid
Matched Description: … A guanido-neuraminic acid that is used to inhibit neuraminidase. …
Matched Categories: … Acids, Acyclic ... Sugar Acids ... Sialic Acids ... Hydroxy Acids ... Carboxylic Acids
Darunavir is a protease inhibitor used with other HIV protease inhibitor drugs as well as ritonavir for the effective management of HIV-1 infection. As a second-generation protease inhibitor, darunavir is designed to combat resistance to standard HIV therapy.[A2278,A2281] It was initially approved by the FDA in 2006. Darunavir is being...
Approved
Matched Synonyms: … [(S)-3-[(4-Amino-benzenesulfonyl)-isobutyl-amino]-2-hydroxy-1-((R)-phenylmethyl)-propyl]-carbamic acid ... {(1S,2R)-3-[(4-Amino-benzenesulfonyl)-isobutyl-amino]-1-benzyl-2-hydroxy-propyl}-carbamic acid (3R,3aS …
Matched Description: … [A191682] Clinical trials are underway and are expected to conclude in August 2020.[L12066] …
Matched Salts name: … Darunavir dihydrate
Matched Categories: … Carboxylic Acids ... darunavir and ritonavir ... darunavir and cobicistat ... Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics …
Matched Products: … Darunavir 600 and 800 mg …
Levonorgestrel (LNG) is a synthetic progestogen similar to Progesterone used in contraception and hormone therapy.[A181988,T659] Also known as Plan B, it is used as a single agent in emergency contraception, and as a hormonal contraceptive released from an intrauterine device, commonly referred to as an IUD. Some of these devices...
Approved
Investigational
Matched Description: … Some of these devices are known as Jaydess, Kyleena, and Mirena. ... Levonorgestrel (LNG) is a synthetic progestogen similar to [Progesterone] used in contraception and hormone ... [A181988,T659] Also known as Plan B, it is used as a single agent in emergency contraception, and as …
Matched Mixtures name: … Levonorgestrel and Ethinyl Estradiol and Ethinyl Estradiol ... Levonorgestrel and Ethinyl Estradiol and Ethinyl Estradiol ... Levonorgestrel and Ethinyl Estradiol and Ethinyl Estradiol …
Matched Categories: … levonorgestrel and estrogen ... levonorgestrel and estrogen ... Genito Urinary System and Sex Hormones ... levonorgestrel and ethinylestradiol ... levonorgestrel and ethinylestradiol …
Matched Products: … ONE-AND-ONE …
Paroxetine is a selective serotonin reuptake inhibitor (SSRI) drug commonly known as Paxil. It has a variety of uses, including the treatment of anxiety disorders, major depression, posttraumatic stress disorder, and symptoms of menopause, among others. It was approved by the FDA in the early 1990s and marketed by SmithKline...
Approved
Investigational
Matched Description: … of serotonin reuptake and has little effect on other neurotransmitters. ... [T653] It was approved by the FDA in the early 1990s and marketed by SmithKline Beecham. ... uses, including the treatment of anxiety disorders, major depression, posttraumatic stress disorder, and
Matched Products: … Paroxetine Hydrochloride Anhydrous
Phytic acid is under investigation in clinical trial NCT01000233 (Value of Oral Phytate (InsP6) in the Prevention of Progression of the Cardiovascular Calcifications).
Investigational
Matched Synonyms: … Fytic acid ... Acido fitico ... Acide fytique …
Matched Name: … Phytic acid
Matched Iupac: … {[(1s,2R,3R,4r,5S,6S)-2,3,4,5,6-pentakis(phosphonooxy)cyclohexyl]oxy}phosphonic acid
Matched Description: … Phytic acid is under investigation in clinical trial NCT01000233 (Value of Oral Phytate (InsP6) in the …
Acyclovir is a deoxynucleoside analog antiviral used to treat herpes simplex, Varicella zoster, herpes zoster, herpes labialis, and acute herpetic keratitis.[L7303,L7315,L7318,L7321,L7324,L7327] Acyclovir is generally used first line in the treatment of these viruses and some products are indicated for patients as young as 6 years old. Acyclovir was granted FDA...
Approved
Matched Description: … analog antiviral used to treat herpes simplex, _Varicella zoster_, herpes zoster, herpes labialis, and ... L7315,L7318,L7321,L7324,L7327] Acyclovir is generally used first line in the treatment of these viruses and
Matched Categories: … Nucleic Acid Synthesis Inhibitors ... Acyclovir and prodrug ... Nucleosides and Nucleotides ... Nucleosides and Nucleotides Excl. Reverse Transcriptase Inhibitors …
Matched Products: … ACIC 200 ... ACIC 400 ... ACIC 800 …
Sparfosic acid is a solid. This compound belongs to the n-acyl-alpha amino acids. These are compounds containing an alpha amino acid which bears an acyl group at the terminal nitrogen atom. This substance is known to target aspartate carbamoyltransferase catalytic chain and CAD protein.
Experimental
Matched Synonyms: … Acidum sparfosicum ... Sparfosic acid ... N-(phosphonacetyl)-L-aspartic acid
Matched Name: … Sparfosic acid
Matched Iupac: … (2S)-2-(2-phosphonoacetamido)butanedioic acid
Matched Description: … This substance is known to target aspartate carbamoyltransferase catalytic chain and CAD protein. ... Sparfosic acid is a solid. This compound belongs to the n-acyl-alpha amino acids. ... These are compounds containing an alpha amino acid which bears an acyl group at the terminal nitrogen …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids, Acidic ... Amino Acids ... Acids, Acyclic ... Carboxylic Acids
Displaying drugs 601 - 625 of 2505 in total