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Displaying drugs 601 - 625 of 1064 in total
Remestemcel-L is a third-party, off-the-shelf suspension of ex-vivo cultured adult human mesenchymal stem cells intended for intravenous infusion. The mesenchymal stem cells are derived from the bone marrow of unrelated and human leukocyte antigen (HLA)–unmatched healthy adult donors and have the ability to differentiate into different tissue cells. It was...
Approved
Investigational
Matched Synonyms: … Adult human mesenchymal stem cells ... Allogeneic human mesenchymal stem cell …
Matched Description: … cytokines and growth factors to promote tissue repair [A31818]. ... Based on its tolerability and safety profile, remestemcel-L is a promising alternative to second-line ... The mesenchymal stem cells are derived from the bone marrow of unrelated and human leukocyte antigen …
Bertilimumab is a fully human anti-eotaxin monoclonal antibody with potential in the treatment of allergic disorders, has moved into pre-clinical development. It is developed by MedImmune for the treatment of Allergic Rhinitis.
Investigational
Matched Synonyms: … IMMUNOGLOBULIN G4, ANTI-(HUMAN EOTAXIN 1) (HUMAN MONOCLONAL CAT-213 .GAMMA.4-CHAIN), DISULFIDE WITH HUMAN
Matched Description: … Bertilimumab is a fully human anti-eotaxin monoclonal antibody with potential in the treatment of allergic …
Nipocalimab is under investigation in clinical trial NCT04119050 (Efficacy and Safety of M281 in Adults With Warm Autoimmune Hemolytic Anemia).
Investigational
Matched Synonyms: … Immunoglobulin g1, anti-(human neonatal fc receptor) (human monoclonal m281 .gamma.-1 chain), disulfide ... with human monoclonal m281 .lambda. …
Matched Description: … Nipocalimab is under investigation in clinical trial NCT04119050 (Efficacy and Safety of M281 in Adults …
Vonlerolizumab is under investigation in clinical trial NCT03029832 (A Study of MOXR0916 in Combination With Atezolizumab Versus Atezolizumab Alone in Participants With Untreated Locally Advanced or Metastatic Urothelial Carcinoma Who Are Ineligible for Cisplatin-based Therapy).
Investigational
Matched Synonyms: … Immunoglobulin g1-kappa, anti-(human tumor necrosis factor receptor superfamily member 4 (act35 antigen ... Immunoglobulin g1-kappa, anti-(homo sapiens tnfrsf4(tumor necrosis factor receptor (tnfr) superfamily …
Matched Description: … With Untreated Locally Advanced or Metastatic Urothelial Carcinoma Who Are Ineligible for Cisplatin-based
Matched Categories: … Amino Acids, Peptides, and Proteins …
Endothelin 1 is under investigation in clinical trial NCT00745693 (The Effects of Diesel Exhaust Inhalation on Vascular Function - the Role of Endothelin).
Investigational
Matched Synonyms: … Human endothelin ... Endothelin 1 (human) …
Matched Categories: … Biological Factors ... Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins …
Elotuzumab is a humanized IgG1 (Immunoglobulin G) monoclonal antibody indicated in combination with lenalidomide and dexamethasone for the treatment of patients with multiple myeloma who have received one to three prior therapies. Elotuzumab targets SLAMF7, also known as Signaling Lymphocytic Activation Molecule Family member 7, a cell surface glycoprotein. Elotuzumab...
Approved
Matched Synonyms: … Immunoglobulin G1, anti-(human protein CS1) (human-mouse HuLuc63 heavy chain), disulfide with human-mouse …
Matched Description: … Food and Drug Administration. ... IgG1 heavy and kappa light chain frameworks. ... a humanized IgG1 (Immunoglobulin G) monoclonal antibody indicated in combination with lenalidomide and
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES …
Debamestrocel consists of autologous mesenchymal stromal cells secreting neurotrophic factors. Debamestrocel is under clinical development by BrainStorm Cell Therapeutics and is being investigated for the treatment of Amyotrophic Lateral Sclerosis (ALS).
Investigational
Matched Synonyms: … AUTOLOGOUS MESENCHYMAL STROMAL CELLS SECRETING NEUROTROPHIC FACTORS ... AUTOLOGOUS MESENCHYMAL STROMAL CELLS (MSC) SECRETING NEUROTROPHIC FACTORS (NTF) …
Matched Description: … Debamestrocel is under clinical development by BrainStorm Cell Therapeutics and is being investigated ... Debamestrocel consists of autologous mesenchymal stromal cells secreting neurotrophic factors. …
Atibuclimab (IC14) is a chimeric CD14 antibody investigated for the treatment of patients with severe sepsis.
Investigational
Matched Synonyms: … IMMUNOGLOBULIN G4, ANTI-(HUMAN CD14 ANTIGEN) (HUMAN-MUS MUSCULUS MONOCLONAL IC14 .GAMMA.4-CHAIN), DISULFIDE ... IC14, (RECOMBINANT CHIMERIC MAB AGAINST HUMAN CD14) ... WITH HUMAN-MUS MUSCULUS MONOCLONAL IC14 .KAPPA. …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Investigational
Matched Synonyms: … Hepatitis C immune globulin (human) ... Hepatitis C human polyclonal immune globulin ... Hepatitis C virus immune globulin (human) …
Matched Name: … Hepatitis C immune globulin (human) …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Filgrastim is a short-acting recombinant, non-pegylated human granulocyte colony-stimulating factor (G-CSF) analog produced by recombinant DNA technology. It has an amino acid sequence identical to endogenous G-CSF, but it is non-glycosylated unlike the endogenous G-CSF and has an N-terminal methionine added in the sequence for expression in E. Coli. Human...
Approved
Matched Synonyms: … Granulocyte Colony Stimulating Factor
Matched Description: … Filgrastim is a short-acting recombinant, non-pegylated human granulocyte colony-stimulating factor ( ... [L40714] Human G-CSF is a glycoprotein that regulates the production and release of neutrophils from ... [L40719] It has a number of therapeutic uses, including the management and prevention of infections and
Matched Categories: … Leukocyte Growth Factor ... Hematopoietic Cell Growth Factors ... Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Biological Factors
Pristinamycin IIA is a macrolide antibiotic, a member of the streptogramin A group of antibiotics, and one component of pristinamycin. It is produced by Streptomyces graminofaciens and other bacteria.
Experimental
Matched Synonyms: … Virginiamycin factor M1 …
Matched Description: … It is produced by Streptomyces graminofaciens and other bacteria. ... Pristinamycin IIA is a macrolide antibiotic, a member of the streptogramin A group of antibiotics, and
Matched Categories: … Amino Acids, Peptides, and Proteins …
Investigational
Matched Synonyms: … Haptoglobin (Hp1-1), (Human) …
Human Lactoferrin Peptide hLF1-11 is under investigation in clinical trial NCT00509834 (A Study on the Tolerability and Early Efficacy of Hlf1-11 in Patients With Proven Candidaemia).
Investigational
Matched Synonyms: … Human lactoferrin 1-11 ... N-terminal peptide of human lactoferrin 1-11 …
Matched Name: … Human Lactoferrin Peptide hLF1-11 …
Matched Description: … Tolerability and Early Efficacy of Hlf1-11 in Patients With Proven Candidaemia). ... Human Lactoferrin Peptide hLF1-11 is under investigation in clinical trial NCT00509834 (A Study on the …
Lemzoparlimab is under investigation in clinical trial NCT04912063 (Study to Evaluate Adverse Events and Movement of Lemzoparlimab in Body When Used Intravenously (IV) With Azacitidine Subcutaneously or IV and Venetoclax Orally in Participants With Acute Myeloid Leukemia and With Azacitidine With or Without Venetoclax in Participants With Myelodysplastic Syndrome).
Investigational
Matched Synonyms: … Immunoglobulin g4(228-proline), anti-(human cd47 antigen) (human monoclonal tj011133 .gamma.4-chain), ... disulfide with human monoclonal tj011133 .kappa. …
Matched Description: … Lemzoparlimab is under investigation in clinical trial NCT04912063 (Study to Evaluate Adverse Events and ... Movement of Lemzoparlimab in Body When Used Intravenously (IV) With Azacitidine Subcutaneously or IV and ... Venetoclax Orally in Participants With Acute Myeloid Leukemia and With Azacitidine With or Without Venetoclax …
Efzofitimod (ATYR1923) is a fusion protein comprised of the immuno-modulatory domain of histidyl tRNA synthetase fused to the FC region of a human antibody. It is a selective modulator of neuropilin-2 that downregulates the innate and adaptive immune response in inflammatory disease states.
Investigational
Matched Synonyms: … Human IgG1Fc- iMod domain (amino acids 2-60) of human HARS fusion protein …
Matched Description: … It is a selective modulator of neuropilin-2 that downregulates the innate and adaptive immune response ... protein comprised of the immuno-modulatory domain of histidyl tRNA synthetase fused to the FC region of a human
Investigational
Matched Synonyms: … Human coxsackievirus A21 ... Enterovirus human enterovirus C serogroup coxsackievirus serotype A21 …
Aprotinin is a protein-based drug that is also known as bovine pancreatic trypsin inhibitor (BPTI). Since it demonstrates the capacity to slow fibrinolysis, it has been employed to reduce bleeding during complex surgery such as heart and liver surgery. For this use, it is typically administered by injection. The goal...
Approved
Investigational
Withdrawn
Matched Synonyms: … Trypsin inhibitor, pancreatic basic
Matched Description: … to slow fibrinolysis, it has been employed to reduce bleeding during complex surgery such as heart and ... was subsequently to minimize end-organ damage resulting from hypotension due to blood loss in surgery and ... Aprotinin is a protein-based drug that is also known as bovine pancreatic trypsin inhibitor (BPTI). …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Blood and Blood Forming Organs …
Human papillomavirus type 18 L1 capsid protein antigen is contained in Gardasil, or a recombinant Human Papillomavirus Quadrivalent (Types 6, 11, 16, and 18) vaccine for intramuscular injection. It is an immunization for young men and women 9-26 years of age for the prevention of diseases caused by Human Papillomavirus...
Approved
Investigational
Matched Synonyms: … L1 protein, Human papillomavirus type 18 Vaccine ... Recombinant human papillomavirus type 18 L1 protein …
Matched Name: … Human papillomavirus type 18 L1 capsid protein antigen …
Matched Description: … by Human Papillomavirus (HPV) types 6, 11, 16 and 18. ... Human papillomavirus type 18 L1 capsid protein antigen is contained in Gardasil, or a recombinant Human ... Papillomavirus Quadrivalent (Types 6, 11, 16, and 18) vaccine for intramuscular injection. …
Matched Mixtures name: … Gardasil 9 [Human Papillomavirus 9-valent Vaccine, Recombinant] ... GARDASIL® 9 VACUNA RECOMBINANTE NONAVALENTE CONTRA EL VIRUS DEL PAPILOMA HUMANO
Matched Categories: … Inactivated Human Papillomavirus Vaccine …
Human papillomavirus type 31 L1 capsid protein antigen is contained in Gardasil is a vaccine for intramuscular injection. It is an immunization for young men and women 9-26 years of age for the prevention of diseases caused by Human Papillomavirus (HPV) type 31. The vaccine is prepared from the purified...
Approved
Matched Synonyms: … L1 protein, Human papillomavirus type 31 Vaccine ... Recombinant human papillomavirus type 31 L1 protein …
Matched Name: … Human papillomavirus type 31 L1 capsid protein antigen …
Matched Description: … It is an immunization for young men and women 9-26 years of age for the prevention of diseases caused ... HPV Type 31 which are produced by separate fermentations in recombinant *Saccharomyces cerevisiae* and ... by Human Papillomavirus (HPV) type 31. …
Matched Mixtures name: … Gardasil 9 [Human Papillomavirus 9-valent Vaccine, Recombinant] ... GARDASIL® 9 VACUNA RECOMBINANTE NONAVALENTE CONTRA EL VIRUS DEL PAPILOMA HUMANO
Human papillomavirus type 45 L1 capsid protein antigen is contained in Gardasil is a vaccine for intramuscular injection. It is an immunization for young men and women 9-26 years of age for the prevention of diseases caused by Human Papillomavirus (HPV) type 45. The vaccine is prepared from the purified...
Approved
Matched Synonyms: … L1 protein, Human papillomavirus type 45 Vaccine ... Recombinant human papillomavirus type 45 L1 protein …
Matched Name: … Human papillomavirus type 45 L1 capsid protein antigen …
Matched Description: … It is an immunization for young men and women 9-26 years of age for the prevention of diseases caused ... HPV Type 45 which are produced by separate fermentations in recombinant *Saccharomyces cerevisiae* and ... by Human Papillomavirus (HPV) type 45. …
Matched Mixtures name: … Gardasil 9 [Human Papillomavirus 9-valent Vaccine, Recombinant] ... GARDASIL® 9 VACUNA RECOMBINANTE NONAVALENTE CONTRA EL VIRUS DEL PAPILOMA HUMANO
Human papillomavirus type 52L1 capsid protein antigen is contained in Gardasil is a vaccine for intramuscular injection. It is an immunization for young men and women 9-26 years of age for the prevention of diseases caused by Human Papillomavirus (HPV) type 52 The vaccine is prepared from the purified virus-like...
Approved
Matched Synonyms: … L1 protein, Human papillomavirus type 52 Vaccine ... Recombinant human papillomavirus type 52 L1 protein …
Matched Name: … Human papillomavirus type 52 L1 capsid protein antigen …
Matched Description: … It is an immunization for young men and women 9-26 years of age for the prevention of diseases caused ... HPV Type 52 which are produced by separate fermentations in recombinant *Saccharomyces cerevisiae* and ... Human papillomavirus type 52L1 capsid protein antigen is contained in Gardasil is a vaccine for intramuscular …
Matched Mixtures name: … Gardasil 9 [Human Papillomavirus 9-valent Vaccine, Recombinant] ... GARDASIL® 9 VACUNA RECOMBINANTE NONAVALENTE CONTRA EL VIRUS DEL PAPILOMA HUMANO
Thymalfasin is a chemically synthesized version of thymosin alpha 1 that is identical to human thymosin alpha 1. Thymosin alpha 1 is an acetylated polypeptide. Thymosin alpha 1 is now approved in 35 developing countries for the treatment of Hepatitis B and C. It is also used to boost the...
Investigational
Matched Synonyms: … Thymosin alpha1 (human) …
Matched Description: … Thymosin alpha 1 is now approved in 35 developing countries for the treatment of Hepatitis B and C. ... Thymalfasin is a chemically synthesized version of thymosin alpha 1 that is identical to human thymosin …
Matched Categories: … Immunologic Factors ... Amino Acids, Peptides, and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
The respiratory protein of the red blood cells. It consists primarily of globin and heme.
Approved
Experimental
Investigational
Matched Synonyms: … Human hemoglobin …
Matched Description: … It consists primarily of globin and heme. …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Zolbetuximab is under investigation in clinical trial NCT01630083 (Efficacy and Safety of IMAB362 in Combination With the EOX Regimen for CLDN18.2-positive Gastric Cancer).
Investigational
Matched Synonyms: … immunoglobulin G1, anti-(human Claudin-18.2) (human-mus musculus monoclonal IMAB362 heavy chain), disulfide ... with human-mus musculus monoclonal IMAB362 .kappa. …
Matched Description: … Zolbetuximab is under investigation in clinical trial NCT01630083 (Efficacy and Safety of IMAB362 in …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Bassia scoparia pollen is the pollen of the Bassia scoparia plant. Bassia scoparia pollen is mainly used in allergenic testing.
Approved
Matched Name: … Bassia scoparia pollen …
Matched Description: … Bassia scoparia pollen is the pollen of the Bassia scoparia plant. ... Bassia scoparia pollen is mainly used in allergenic testing. …
Displaying drugs 601 - 625 of 1064 in total