Advanced Filter

Filter by Group

Filter by Market Availability

Displaying drugs 601 - 625 of 844 in total
Approved
Experimental
Matched Synonyms: … Bis(dimethylthiocarbamoyl) sulfide
Diclofenac is a phenylacetic acid derivative and non-steroidal anti-inflammatory drug (NSAID).[label] NSAIDs inhibit cyclooxygenase (COX)-1 and-2 which are the enzyme responsible for producing prostaglandins (PGs). PGs contribute to inflammation and pain signalling. Diclofenac, like other NSAIDs, is often used as first line therapy for acute and chronic pain and inflammation...
Approved
Vet approved
Matched Description: … Diclofenac, like other NSAIDs, is often used as first line therapy for acute and chronic pain and inflammation ... PGs contribute to inflammation and pain signalling. ... Diclofenac is a phenylacetic acid derivative and non-steroidal anti-inflammatory drug (NSAID). …
Matched Mixtures name: … Diclofenac Sodium and Misoprostol Delayed-Release ... Diclofenac Sodium and Misoprostol ... Diclofenac Sodium and Misoprostol …
Matched Salts name: … Diclofenac potassium
Matched Categories: … Musculo-Skeletal System ... Acetic Acid Derivatives and Related Substances ... Antiinflammatory and Antirheumatic Products ... diclofenac and antiinfectives ... Antiinflammatory and Antirheumatic Products, Non-Steroids …
Matched Products: … Up and Up Arthritis Pain Reliever ... Diclofenac Potassium ... DICLOFENAC POTASSIUM
CTX110 is an allogeneic CRISPR/Cas9-mediated genetically modified CAR T cell therapy targeting CD19 antigen.
Investigational
Matched Synonyms: … allogeneic CRISPR/Cas9-mediated genetically modified CAR T cells targeting CD19 antigen …
Matched Description: … CTX110 is an allogeneic CRISPR/Cas9-mediated genetically modified CAR T cell therapy targeting CD19 antigen …
Naxitamab (humanized 3F8, hu3F8) is an IgG1 monoclonal antibody directed against the oncofetal differentiation antigen GD2 disialoganglioside.[L24454,A224604] Normally expressed during fetal development and in mature neurons, pain fibers, and skin cells, GD2 constitutes a highly efficient target in the treatment of neuroblastoma - it is widely expressed across and within...
Approved
Matched Synonyms: … Monoclonal antibody HU3F8 ... Anti-Gd2 monoclonal antibody 3F8 humanized ... Humanized monoclonal antibody HU3F8-IGG1 …
Matched Description: … [L24454,A224604] Normally expressed during fetal development and in mature neurons, pain fibers, and ... within neuroblastomas (and other neuroectodermal tumors),[A224609] and is rarely subject to antigen ... constitutes a highly efficient target in the treatment of neuroblastoma - it is widely expressed across and
Matched Categories: … MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES ... Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Glycolipid Disialoganglioside-directed Antibody ... Glycolipid Disialoganglioside-directed Antibody Interactions …
Integrins are important adhesion molecules that regulate tumor and endothelial cell survival, proliferation and migration. The integrin alpha5beta1 has been shown to play a critical role during angiogenesis. anti-alpha5beta1 integrin antibody inhibits angiogenesis, including vessel formation induced by vascular endothelial growth factor (VEGF), basic fibroblast growth factor (bFGF), as well...
Investigational
Matched Name: … anti-alpha5Beta1-integrin antibody
Matched Description: … and migration. ... Integrins are important adhesion molecules that regulate tumor and endothelial cell survival, proliferation ... integrin alpha5beta1 has been shown to play a critical role during angiogenesis. anti-alpha5beta1 integrin antibody
Investigational
Matched Synonyms: … Humanized monoclonal antibody Hu11E6 …
Matched Name: … Humanized monoclonal antibody Hu11E6 …
Pertuzumab is a recombinant humanized monoclonal antibody that targets the extracellular dimerization domain (subdomain II) of the human epidermal growth factor receptor 2 protein (HER2). It consists of two heavy chains and two lights chains that have 448 and 214 residues respectively. It was first approved by the FDA in...
Approved
Matched Synonyms: … 2C4 Antibody ... Monoclonal Antibody 2C4 …
Matched Description: … It consists of two heavy chains and two lights chains that have 448 and 214 residues respectively. ... It was first approved by the FDA in 2012 for use with [docetaxel] and another HER2-targeted monoclonal ... Its indicated conditions have since expanded to include use as both a neoadjuvant therapy and an adjuvant …
Matched Categories: … MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES ... Amino Acids, Peptides, and Proteins ... pertuzumab and trastuzumab ... Antineoplastic and Immunomodulating Agents …
BB-1701 is a humanized IgG1 kappa monoclonal antibody (anti-HER2 antibody) conjugated to eribulin developed by Bliss Biopharmaceutical.
Investigational
Matched Synonyms: … Humanized IgG1kappa monoclonal antibody (anti-HER2 antibody) conjugated to eribulin …
Matched Description: … BB-1701 is a humanized IgG1 kappa monoclonal antibody (anti-HER2 antibody) conjugated to eribulin developed …
Investigational
Matched Synonyms: … Monoclonal antibody PM-81 ... Anti-CD15 monoclonal antibody PM-81 ... Anti-AML/SCCL-trigger monoclonal antibody
Bithionol, formerly marketed as an active ingredient in various topical drug products, was shown to be a potent photosensitizer with the potential to cause serious skin disorders. Approvals of the NDA's for bithionol drug products were withdrawn on October 24, 1967 (see the Federal Register of October 31, 1967 (32...
Approved
Withdrawn
Matched Synonyms: … Bithionol sulfide ... 2-Hydroxy-3,5-dichlorophenyl sulfide ... Bis(3,5-dichloro-2-hydroxyphenyl) sulfide
Matched Categories: … Antiparasitic Products, Insecticides and Repellents …
Sodium sulfide is a chemical compound with a chemical formula Na2S. Sodium sulfide is used in the pulp and paper industry, water treatment, textile industry, and various chemical manufacturing processes including the production of rubber chemicals, sulfur dyes and oil recovery. Along with its hydrate form, sodium sulfide releases hydrogen...
Approved
Matched Name: … Sodium sulfide
Matched Description: … Sodium sulfide is used in the pulp and paper industry, water treatment, textile industry, and various ... However the clinical significance and mechanism of action of sodium sulfide and replication of results ... Along with other sulfides, the anti-inflammatory and tissue-protective effects of sodium sulfide have …
Matched Categories: … Hydrogen Sulfide
Investigational
Matched Name: … Lansoprazole sulfone
Anti-GD2 monoclonal antibody 3F8 is under investigation in clinical trial NCT00089258 (Biological Therapy in Treating Patients With Neuroblastoma That Has Not Responded to Previous Treatment).
Investigational
Matched Synonyms: … MONOCLONAL ANTIBODY 3F8 ... ANTI-GD2 MOUSE MONOCLONAL ANTIBODY 3F8 (IGG3) …
Matched Name: … Anti-GD2 monoclonal antibody 3F8 …
Matched Description: … Anti-GD2 monoclonal antibody 3F8 is under investigation in clinical trial NCT00089258 (Biological Therapy …
Tividenofusp alfa, also known as DNL-310, is a brain-penetrant enzyme replacement therapy being investigated for the treatment of Hunter syndrome.
Investigational
Matched Synonyms: … DNL-310, recombinant iduronate 2-sulfatase
Rivastigmine is a parasympathomimetic or cholinergic agent for the treatment of mild to moderate dementia of the Alzheimer's type. Rivastigmine is a cholinesterase inhibitor that inhibits both butyrylcholinesterase and acetylcholinesterase.
Approved
Investigational
Matched Description: … Rivastigmine is a cholinesterase inhibitor that inhibits both butyrylcholinesterase and acetylcholinesterase …
Matched Salts name: … Rivastigmine tartrate
Matched Products: … Rivastigmine Tartrate ... Rivastigmine Tartrate Capsules …
Pabinafusp alfa is under investigation in clinical trial NCT03568175 (A Study of JR-141 in Patients With Mucopolysaccharidosis II).
Investigational
Matched Synonyms: … Immunoglobulin G1-kappa, anti-(human transferrin receptor 1, tfr1) humanized monoclonal antibody, fused ... with human iduronate-2-sulfatase, glycoform alfa: ... ) FUSION PROTEIN WITH PEPTIDE (SYNTHETIC 2-AMINO ACID LINKER) FUSION PROTEIN WITH HUMAN IDURONATE-2-SULFATASE
Matched Categories: … Enzymes and Coenzymes ... Alimentary Tract and Metabolism …
Olitigaltin has been investigated for the treatment of Idiopathic Pulmonary Fibrosis.
Investigational
Matched Synonyms: … Bis-(3-deoxy-3-(4-(3-fluorophenyl)-1H-1,2,3-triazol-1-yl)-B-D-galactopyranosyl) sulfane
CTX120 is an allogeneic CRISPR/Cas9-mediated genetically modified CAR T cell therapy targeting B-cell maturation antigen.
Investigational
Matched Synonyms: … allogeneic CRISPR/Cas9-mediated genetically modified CAR T cells targeting B-cell maturation antigen …
Matched Description: … CTX120 is an allogeneic CRISPR/Cas9-mediated genetically modified CAR T cell therapy targeting B-cell …
Investigational
Matched Synonyms: … anti-Cd33 monoclonal antibody BI 836858 ... Fully Human Igg1 Antibody Specific For Cd33 …
Matched Categories: … Amino Acids, Peptides, and Proteins …
There is a great deal of evidence indicating that vascular endothelial growth factor (VEGF) is important for the survival and proliferation of cancer cells.[A192939,A192837,A192891,A193275] VEGF plays an important role in angiogenesis, lymphangiogenesis, and tumor growth, which are all factors that contribute to its attractiveness as a therapeutic target for anti-cancer...
Approved
Investigational
Matched Synonyms: … Anti-VEGF monoclonal antibody ... Anti-VEGF Humanized Monoclonal Antibody
Matched Description: … [A193272,A193275] It is a humanized monoclonal IgG antibody, and inhibits angiogenesis by binding and ... of evidence indicating that vascular endothelial growth factor (VEGF) is important for the survival and ... [A192939,A192837,A192891,A193275] VEGF plays an important role in angiogenesis, lymphangiogenesis, and
Matched Categories: … MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES ... Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Vascular Endothelial Growth Factor-directed Antibody Interactions …
2G7 is an anti-TGF-beta monoclonal antibody developed by Genentech.
Investigational
Matched Synonyms: … Anti-TGF-beta antibody 2G7 ... Anti-TGF-beta monoclonal antibody 2G7 ... Anti-transforming growth factor-beta monoclonal antibody 2G7 …
Matched Description: … 2G7 is an anti-TGF-beta monoclonal antibody developed by Genentech. …
Immunoglobulin G1, anti-(human CD30 (antigen)) (human monoclonal MDX-060 heavy chain), disulfide with human monoclonal MDX-060 light chain, dimer. Molecular weight is approximately 170,000 daltons. In phase I/II clinical trials for treatment of CD30+ lymphomas.
Investigational
Matched Synonyms: … 5F11 monoclonal antibody
Matched Categories: … Amino Acids, Peptides, and Proteins …
Topiramate is a anti-epileptic drug used to manage seizures and prevent migraines. It was initially approved by the FDA in 1996. In 2004, topiramate was approved for the prevention of migraine in adults.[A188309,L10544,L43478] Since 2012, the extended-release formulation has been approved in combination with phentermine for chronic weight management therapy...
Approved
Matched Synonyms: … 2,3:4,5-di-O-isopropylidene-β-D-fructopyranose sulfamate ... 2,3:4,5-bis-O-(1-methylethylidene)-β-D-fructopyranose sulfamate
Matched Iupac: … [(1R,2S,6S,9R)-4,4,11,11-tetramethyl-3,5,7,10,12-pentaoxatricyclo[7.3.0.0^{2,6}]dodecan-6-yl]methyl sulfamate
Matched Description: … , and 40% of its mass accounted for by oxygen. ... Topiramate is a anti-epileptic drug used to manage seizures and prevent migraines. ... distinguish topiramate from other antiepileptic drugs are a monosaccharide chemical structure containing a sulfamate
Matched Salts name: … Topiramate potassium
Matched Categories: … Alimentary Tract and Metabolism ... phentermine and topiramate …
The humanized anti-IL-12 antibody is an important addition to PDL's already strong pipeline of humanized antibodies being developed for the treatment of autoimmune diseases. SMART Anti-IL-12 Antibody was humanized at PDL from a murine anti-IL-12 antibody that was licensed, together with certain intellectual property related to anti-IL-12 therapy, from Hoffmann-La...
Investigational
Matched Name: … humanized SMART Anti-IL-12 Antibody
Matched Description: … SMART Anti-IL-12 Antibody was humanized at PDL from a murine anti-IL-12 antibody that was licensed, together ... The humanized anti-IL-12 antibody is an important addition to PDL's already strong pipeline of humanized …
Experimental
Matched Name: … Calcium magnesium potassium carbonate chloride hydroxide …
Displaying drugs 601 - 625 of 844 in total