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Displaying drugs 601 - 625 of 15492 in total

Fluoride ion

Having a chemical formula of F−, fluoride ion is the simplest inorganic, monatomic anion of fluorine with basic properties. It is considered a trace element. Fluoride ions are found in various minerals but are only present in trace amounts in water. Its various salt forms and minerals play numerous roles...
Approved
Matched Description: … Its various salt forms and minerals play numerous roles as chemical reagents, industrial chemicals, and ... It also plays an essential physiological role, such as enhancing the resistance profile and strength …
Matched Mixtures name: … Multi-Vitamin Fluoride and Iron Drops …

Plazomicin

Developed by Achaogen biopharmaceuticals, plazomicin is a next-generation aminoglycoside synthetically derived from DB12604. The structure of plazomicin was established via appending hydroxylaminobutyric acid to DB12604 at position 1 and 2-hydroxyethyl group at position 6' . It was designed to evade all clinically relevant aminoglycoside-modifying enzymes, which contribute to the main...
Approved
Investigational
Matched Description: … ribosomal modification by bacteria, which results from amino acid or rRNA sequence mutations [A33942 ... The structure of plazomicin was established via appending hydroxylaminobutyric acid to [DB12604] at position ... 1 and 2-hydroxyethyl group at position 6' [A33942]. …

Azithromycin

Azithromycin is a broad-spectrum macrolide antibiotic with a long half-life and a high degree of tissue penetration . It was initially approved by the FDA in 1991 . It is primarily used for the treatment of respiratory, enteric and genitourinary infections and may be used instead of other macrolides for...
Approved
Matched Description: … It is primarily used for the treatment of respiratory, enteric and genitourinary infections and may be ... used instead of other macrolides for some sexually transmitted and enteric infections. ... Azithromycin is a broad-spectrum macrolide antibiotic with a long half-life and a high degree of tissue …
Matched Categories: … cefixime and azithromycin ... azithromycin, fluconazole and secnidazole ... Macrolides, Lincosamides and Streptogramins …
Matched Products: … MENAZİD-L 500 MG IV ENJEKSİYONLUK LİYOFİLİZE TOZ İÇEREN FLAKON, 1 ADET …

Bromocriptine

Bromocriptine mesylate is a semisynthetic ergot alkaloid derivative with potent dopaminergic activity. It inhibits prolactin secretion and may be used to treat dysfunctions associated with hyperprolactinemia. Bromocriptine is also indicated for the management of signs and symptoms of Parkinsonian Syndrome, as well as the treatment of acromegaly. Bromocriptine has been...
Approved
Investigational
Withdrawn
Matched Description: … Bromocriptine is also indicated for the management of signs and symptoms of Parkinsonian Syndrome, as ... It inhibits prolactin secretion and may be used to treat dysfunctions associated with hyperprolactinemia ... Bromocriptine has been associated with pulmonary fibrosis, and can also cause sustained suppression of …
Matched Categories: … Ergot Alkaloids and Derivatives ... Genito Urinary System and Sex Hormones ... Hormones, Hormone Substitutes, and Hormone Antagonists …

Bisoxatin

Bisoxatin is a stimulant laxative which increases peristalsis and inhibits absorbtion of water and ions in the intestine . It is marketed in Belgium under the tradename Wylaxine and used for the treatment of constipation and for preparation of the colon for surgical procedures.
Approved
Matched Description: … Bisoxatin is a stimulant laxative which increases peristalsis and inhibits absorbtion of water and ions ... It is marketed in Belgium under the tradename Wylaxine and used for the treatment of constipation and …
Matched Categories: … Alimentary Tract and Metabolism …

Dacomitinib

Dacomitinib, designed as (2E)-N-16-4-(piperidin-1-yl) but-2-enamide, is an oral highly selective quinazalone part of the second-generation tyrosine kinase inhibitors which are characterized by the irreversible binding at the ATP domain of the epidermal growth factor receptor family kinase domains. Dacomitinib was developed by Pfizer Inc and approved by the FDA on...
Approved
Investigational
Matched Description: … [A40009] Dacomitinib was developed by Pfizer Inc and approved by the FDA on September 27, 2018. …
Matched Categories: … Antineoplastic and Immunomodulating Agents …

Aclidinium

Aclidinium is an anticholinergic for the long-term management of chronic obstructive pulmonary disease (COPD). It has a much higher propensity to bind to muscarinic receptors than nicotinic receptors. FDA approved on July 24, 2012.
Approved
Matched Categories: … formoterol and aclidinium bromide …

Reviparin

Reviparin is a low molecular weight heparin which seems to have a better safety profile than unfractionated heparin. It is prepared from porcine intestinal mucosa by nitrous acid depolymerization. Reviparin has a molecular weight of 3.9 kDa. It was developed by Abbott laboratories and in 2009, reviparin presented an orphan...
Approved
Investigational
Matched Description: … [A32019] It is prepared from porcine intestinal mucosa by nitrous acid depolymerization. ... [A32021] It was developed by Abbott laboratories and in 2009, reviparin presented an orphan drug designation …
Matched Categories: … Heparin and similars ... Blood and Blood Forming Organs …

Bacillus calmette-guerin substrain tice live antigen

Bacillus calmette-guerin substrain tice live antigen is a vaccine containing attenuated live culture preparation of the Bacillus of Calmette and Guerin (BCG) strain of Mycobacterium bovis for percutaneous use. It is administered to prevent the development of tuberculosis.
Approved
Matched Description: … live antigen is a vaccine containing attenuated live culture preparation of the Bacillus of Calmette and …

Sulfathiazole

Sulfathiazole is a short-acting sulfa drug. It used to be a common oral and topical antimicrobial until less toxic alternatives were discovered. It is still occasionally used, sometimes in combination with sulfabenzamide and sulfacetamide. Except for those formulated for vaginal use, the FDA withdrew its approval for the use of...
Approved
Vet approved
Withdrawn
Matched Description: … It used to be a common oral and topical antimicrobial until less toxic alternatives were discovered. ... It is still occasionally used, sometimes in combination with sulfabenzamide and sulfacetamide. …
Matched Categories: … Sulfonamides and trimethoprim ... Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics …

Quinidine

Quinidine is a D-isomer of quinine present in the bark of the Cinchona tree and similar plant species. This alkaloid was first described in 1848 and has a long history as an antiarrhythmic medication.[A38016,A250050] Quinidine is considered the first antiarrhythmic drug (class Ia) and is moderately efficacious in the acute...
Approved
Investigational
Matched Description: … [A38016] It prolongs cellular action potential by blocking sodium and potassium currents. ... Quinidine is a D-isomer of [quinine] present in the bark of the Cinchona tree and similar plant species ... This alkaloid was first described in 1848 and has a long history as an antiarrhythmic medication. …
Matched Categories: … Quinine and stereoisomer ... Metabolic Side Effects of Drugs and Substances …

Argatroban

Argatroban is a direct, selective thrombin inhibitor. The American College of Cardiologists (ACC) recommend using bivalirudin or argatroban in patients who have had, or at risk for, heparin induced thrombocytopenia (HIT) and are undergoing percutaneous coronary intervention. Argatroban is a non-heparin anticoagulant shown to both normalize platelet count in patients...
Approved
Investigational
Matched Iupac: … carbamimidamido-2-(3-methyl-1,2,3,4-tetrahydroquinoline-8-sulfonamido)pentanoyl]-4-methylpiperidine-2-carboxylic acid …
Matched Description: … Parental anticoagulants must be stopped and a baseline activated partial thromboplastin time must be ... Argatroban is a non-heparin anticoagulant shown to both normalize platelet count in patients with HIT and ... bivalirudin or argatroban in patients who have had, or at risk for, heparin induced thrombocytopenia (HIT) and …
Matched Categories: … Blood and Blood Forming Organs ... Amino Acids, Peptides, and Proteins …

Cresol

Cresol is a hydroxytoluene that can be extracted naturally from coal tar or made synthetically. Pure cresol is a mixture of ortho-, meta-, and para- isomers. Cresols are precursors or synthetic intermediates to various other compounds and materials, including plastics, pesticides, pharmaceuticals, disinfectants, and dyes. Ingestion of cresol induces toxicity...
Approved
Matched Description: … pain, and/or vomiting. ... Ingestion of cresol induces toxicity in humans and can lead to burning of the mouth and throat, abdominal ... Pure cresol is a mixture of ortho-, meta-, and para- isomers. …

Simeprevir

Simeprevir is a hepatitis C virus (HCV) NS3/4A protease inhibitor indicated in patient's with HCV genotype 1 for the treatment of chronic hepatitis C virus (HCV) infection. HCV is a single-stranded RNA virus that is categorized into nine distinct genotypes, with genotype 1 being the most common in the United...
Approved
Matched Description: … simeprevir-specific amino acid position of 168 also results in higher treatment failure rates [A19630 ... It is shown to display synergistic effects with interferon-α and HCV NS5B inhibitor, and additive effects ... The SVR12 was 83% (29/35) in treatment-naïve patients and 86% (19/22) in relapsing patients. …
Matched Categories: … Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics …

Sorghum halepense pollen

Sorghum halepense pollen is the pollen of the Sorghum halepense plant. Sorghum halepense pollen is mainly used in allergenic testing.
Approved
Matched Mixtures name: … Mixture of Standardized and Non-Standardized Southern Grasses ... Mixture of Twenty-Two Standardized and Non-Standardized Grasses …

Aripiprazole lauroxil

Aripiprazole lauroxil is a long-acting injectable atypical antipsychotic drug used in the treatment of schizophrenia in adult patients. It is a prodrug of aripiprazole, which acts as a partial agonist at the D2 and 5-HT1A receptors, and as an antagonist at the 5-HT2A receptors . Affecting about 1% of the...
Approved
Investigational
Matched Description: … It is a prodrug of [aripiprazole], which acts as a partial agonist at the D2 and 5-HT1A receptors, and ... catanoia, and negative symptoms that include social withdrawal, anhedonia, and flattening of emotional ... patients are faced with social stigma and discriminations. …
Matched Categories: … Aripiprazole and prodrugs …

Lenzumestrocel

Approved
Investigational

Memantine

Initially approved by the FDA in 2013, memantine is an N-methyl-D-aspartate (NMDA) receptor antagonist used in the management of Alzheimer's Disease (AD). It is different from many other Alzheimer's Disease medications, as it works by a different mechanism than the cholinesterase enzyme inhibitors normally employed in the management of Alzheimer's...
Approved
Investigational
Matched Description: … blocks the effects of glutamate, a neurotransmitter in the brain that leads to neuronal excitability and ... doubling every 20 years, the prevalence of Alzheimer's Disease is predicted to reach 66 million by 2030 and …
Matched Mixtures name: … Memantine and Donepezil Hydrochlorides Extended-release ... Memantine and Donepezil Hydrochlorides Extended-release ... Memantine and Donepezil Hydrochlorides Extended-release …
Matched Categories: … Excitatory Amino Acid Antagonists ... donepezil and memantine ... donepezil, memantine and Ginkgo folium …

Chikungunya vaccine (live, attenuated)

Chikungunya virus (CHIKV) is a member of the Alphavirus genus that was first identified in Tanzania in 1952. It is spread primarily by the bite of infected mosquitos of the Aedes genus. Infection with CHIKV causes chikungunya fever, an illness characterized by acute fever and severe, persistent arthralgia. Prior to...
Approved
Matched Description: … , Asia, Europe, and the Indian and Pacific Oceans. ... In late 2013, the first cases were identified in the Caribbean, and it has since spread to most of the ... [A262051] Prior to 2013, chikungunya virus cases and outbreaks had been identified in countries in Africa …

Cabotegravir

Cabotegravir, or GSK1265744, is an HIV-1 integrase inhibitor that is prescribed with the non-nucleoside reverse transcriptase inhibitor, rilpivirine.[A227668,L31188,L31193] Early research into cabotegravir showed it had lower oral bioavailability than dolutegravir, which resulted in the development of long acting monthly intramuscular injection formulation for cabotegravir.[A227668,L31193] Cabotegravir was granted FDA approval on...
Approved
Investigational
Matched Description: … combination product was granted FDA approval for dosing every two months on February 01, 2022 [L40084] and …

Riluzole

A glutamate antagonist (receptors, glutamate) used as an anticonvulsant (anticonvulsants) and to prolong the survival of patients with amyotrophic lateral sclerosis. Riluzole is marketed as Rilutek by Sanofi.
Approved
Investigational
Matched Description: … A glutamate antagonist (receptors, glutamate) used as an anticonvulsant (anticonvulsants) and to prolong …
Matched Categories: … Excitatory Amino Acid Agents ... Excitatory Amino Acid Antagonists …

Frangula purshiana bark

Approved
Experimental
Matched Mixtures name: … Mucinum (cascara and Senna Tablets) …

Resmetirom

Resmetirom is a thyroid hormone receptor-beta (THR-beta) agonist. On March 14, 2024, it was approved by the FDA as the first treatment of liver fibrosis due to noncirrhotic non-alcoholic steatohepatitis (NASH), which is a form of non-alcoholic fatty liver disease (NAFLD). Thyroid hormones directly regulate lipid metabolism in the liver;...
Approved
Investigational
Matched Description: … [A263461] Resmetirom works to reduce liver fat by stimulating fatty acid degradation and oxidation. …

Raloxifene

Raloxifene is a second generation selective estrogen receptor modulator (SERM) that mediates anti-estrogenic effects on breast and uterine tissues, and estrogenic effects on bone, lipid metabolism, and blood coagulation.[A4979,T28] Exhibiting tissue-specific effects distinct from estradiol, raloxifene is the first of the benzothiophene group of antiestrogens to be labelled a SERM....
Approved
Investigational
Matched Description: … uterine tissues, and estrogenic effects on bone, lipid metabolism, and blood coagulation. ... and it does not cause endometrial proliferation. ... generation selective estrogen receptor modulator (SERM) that mediates anti-estrogenic effects on breast and …
Matched Categories: … Genito Urinary System and Sex Hormones ... Sex Hormones and Modulators of the Genital System ... Hormones, Hormone Substitutes, and Hormone Antagonists …

Atriplex lentiformis pollen

Atriplex lentiformis pollen is the pollen of the Atriplex lentiformis plant. Atriplex lentiformis pollen is mainly used in allergenic testing.
Approved
Displaying drugs 601 - 625 of 15492 in total