Displaying drugs 6376 - 6400 of 7408 in total
Tallimustine
Tallimustine, a benzoyl mustard derivative of distamycin A, is an alkylating agent that binds to the minor groove of DNA.[A182036,A182039] It's association with severe myelotoxicity lead to the end of its development in favour of α-halogenoacrylamide derivatives such as brostallicin, which have a favourable cytotoxicity/myelotoxicity ratio.[A182039,A182045] Newer generations of DNA...
Experimental
Matched Iupac: … 4-{4-[bis(2-chloroethyl)amino]benzamido}-N-[5-({5-[(2-carbamimidoylethyl)carbamoyl]-1-methyl-1H-pyrrol …
Ridogrel
Ridogrel is a dual action drug useful for the prevention of systemic thrombo-embolism and as an adjunctive agent to thrombolytic therapy in acute myocardial infarction. However, there currently are no clinical indications for preferential use of ridogrel over aspirin.
Experimental
Matched Iupac: … 5-{[(E)-[(pyridin-3-yl)[3-(trifluoromethyl)phenyl]methylidene]amino]oxy}pentanoic acid …
Methyl 4-thio-beta-D-glucopyranoside
Experimental
Matched Iupac: … (2R,3R,4R,5S,6R)-6-(hydroxymethyl)-2-methoxy-5-sulfanyloxane-3,4-diol …
O2-Sulfo-Glucuronic Acid
Experimental
Matched Iupac: … (2R,3S,4S,5R,6R)-3,4,6-trihydroxy-5-(sulfooxy)oxane-2-carboxylic acid …
8-Methyl-9-Oxoguanine
Experimental
Matched Iupac: … 5-amino-2-methyl-6H,7H-[1,3]oxazolo[5,4-d]pyrimidin-7-one …
Sri-9662
Experimental
Matched Iupac: … 6-[(1Z)-2-(2,5-dimethoxyphenyl)ethenyl]-5-methylpyrido[2,3-d]pyrimidine-2,4-diamine …
7-cyano-7-deazaguanine
Experimental
Matched Iupac: … 4-hydroxy-2-imino-1H,2H,7H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile …
CRA_1144
Experimental
Matched Iupac: … 2-{5-[amino(iminiumyl)methyl]-1H-1,3-benzodiazol-2-yl}benzen-1-olate …
1,4-Dideoxy-O2-Sulfo-Glucuronic Acid
Experimental
Matched Iupac: … (2R,3R,4S,5R,6S)-3,4,6-trihydroxy-5-(sulfooxy)oxane-2-carboxylic acid …
THIO-ATPA
Experimental
Matched Iupac: … 4-[(2S)-2-azaniumyl-2-carboxyethyl]-5-tert-butyl-1,2-thiazol-3-olate …
CP-122721
CP-122721, neurokinin 1 (NK1) antagonist is developed by Pfizer to treat depression, emesis, and inflammatory diseases including asthma and irritable bowel syndrome.
Investigational
Matched Iupac: … (2S,3S)-N-{[2-methoxy-5-(trifluoromethoxy)phenyl]methyl}-2-phenylpiperidin-3-amine …
Dimethylcurcumin
Dimethylcurcumin is a synthetic chemical compound that is loosely based on a compound found in curcumin. It is a novel anti-androgen that enhances androgen receptor degradation.
Investigational
Matched Iupac: … (1E,4Z,6E)-1,7-bis(3,4-dimethoxyphenyl)-5-hydroxyhepta-1,4,6-trien-3-one …
Fipamezole
Investigational
Matched Iupac: … 4-(2-ethyl-5-fluoro-2,3-dihydro-1H-inden-2-yl)-1H-imidazole …
Imidacloprid
Imidacloprid is a neonicotinoid, which is a class of neuro-active insecticides modeled after nicotine. Imidacloprid is a patented chemical, Imidacloprid is manufactured by Bayer Cropscience (part of Bayer AG) and sold under trade names Kohinor, Admire, Advantage, Gaucho, Merit, Confidor, Hachikusan, Premise, Prothor, and Winner. It is marketed as pest...
Vet approved
Matched Iupac: … 2-chloro-5-{[2-(nitroamino)-4,5-dihydro-1H-imidazol-1-yl]methyl}pyridine …
AZD-7762
AZD7762 has been investigated for the treatment of Cancer, Solid Tumors, and Advanced Solid Malignancies.
Investigational
Matched Iupac: … 3-(carbamoylamino)-5-(3-fluorophenyl)-N-[(3S)-piperidin-3-yl]thiophene-2-carboxamide …
GSI-136
GSI-136 has been used in trials studying the treatment of Alzheimer Disease.
Investigational
Matched Iupac: … 5-chloro-N-[(2S)-3-ethyl-1-hydroxypentan-2-yl]thiophene-2-sulfonamide …
Enecadin
Enecadin has been investigated for the treatment of Stroke.
Investigational
Matched Iupac: … 4-(4-fluorophenyl)-2-methyl-6-{[5-(piperidin-1-yl)pentyl]oxy}pyrimidine …
Dimethyl carbate
Dimethyl carbate is used as an insect repellant.
Experimental
Matched Iupac: … 2,3-dimethyl (1R,2S,3R,4S)-bicyclo[2.2.1]hept-5-ene-2,3-dicarboxylate …
Sacubitrilat
A metabolite of LCZ696 with neprilysin inhibitory activity.
Experimental
Matched Iupac: … (2R,4S)-5-{[1,1'-biphenyl]-4-yl}-4-(3-carboxypropanamido)-2-methylpentanoic acid …
AN2898
AN2898 is under investigation in clinical trial NCT01301508 (Efficacy and Safety of AN2898 and AN2728 Topical Ointments to Treat Mild-to-moderate Atopic Dermatitis).
Investigational
Matched Iupac: … 4-[(1-hydroxy-1,3-dihydro-2,1-benzoxaborol-5-yl)oxy]benzene-1,2-dicarbonitrile …
Etonitazene
Experimental
Illicit
Matched Iupac: … (2-{2-[(4-ethoxyphenyl)methyl]-5-nitro-1H-1,3-benzodiazol-1-yl}ethyl)diethylamine …
N-acetyl-beta-D-galactosamine 6-sulfate
Experimental
Matched Iupac: … {[(2R,3R,4R,5R,6R)-5-acetamido-3,4,6-trihydroxyoxan-2-yl]methoxy}sulfonic acid …
Iodo-Willardiine
Experimental
Matched Iupac: … (2S)-2-amino-3-(5-iodo-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)propanoic acid …
Fluoro-Willardiine
Experimental
Matched Iupac: … (2S)-2-amino-3-(5-fluoro-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)propanoic acid …
Displaying drugs 6376 - 6400 of 7408 in total