Displaying drugs 626 - 650 of 6317 in total
Ocriplasmin
Ocriplasmin is a recombinant truncated form of human plasmin with a molecular weight of 27.2 kDa produced by recombinant DNA technology in a Pichia pastoris expression system. Ocriplasmin is a protein made up of 249 amino acids and has two peptide chains. Agent for pharmacologic vitreolysis; thrombolytic agent. FDA approved...
Approved
Matched Description: … Ocriplasmin is a recombinant truncated form of human plasmin with a molecular weight of 27.2 kDa produced ... by recombinant DNA technology in a Pichia pastoris expression system. ... Ocriplasmin is a protein made up of 249 amino acids and has two peptide chains. …
Lemborexant
Lemborexant is a novel dual orexin receptor antagonist used in the treatment of insomnia characterized by difficulties with sleep onset and/or sleep maintenance. Recent research in the field of sleep disorders has revealed that insomnia is likely driven not by the inability of the brain to "switch on" sleep-related circuits,...
Approved
Investigational
Matched Iupac: … (1R,2S)-2-{[(2,4-dimethylpyrimidin-5-yl)oxy]methyl}-2-(3-fluorophenyl)-N-(5-fluoropyridin-2-yl)cyclopropane ... -1-carboxamide …
Matched Description: … Lemborexant is a novel dual orexin receptor antagonist used in the treatment of insomnia characterized ... This novel mechanism of action offers potential advantages over classic hypnotic agents, including a ... favorable adverse effect profile and potentially greater efficacy, and may signal the beginning of a …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Description: … Lemborexant is a novel dual orexin receptor antagonist used in the treatment of insomnia characterized ... This novel mechanism of action offers potential advantages over classic hypnotic agents, including a ... favorable adverse effect profile and potentially greater efficacy, and may signal the beginning of a …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Procainamide
A derivative of procaine with less CNS action.
Approved
Matched Synonyms: … p-Amino-N-(2-diethylaminoethyl)benzamide …
Matched Iupac: … 4-amino-N-[2-(diethylamino)ethyl]benzamide …
Matched Description: … A derivative of procaine with less CNS action. …
Matched Salts cas: … 614-39-1 …
Matched Categories: … MATE 1 Substrates with a Narrow Therapeutic Index ... MATE 2 Substrates with a Narrow Therapeutic Index ... MATE 1 Substrates ... MATE 2 Substrates ... OCT2 Substrates with a Narrow Therapeutic Index …
Matched Iupac: … 4-amino-N-[2-(diethylamino)ethyl]benzamide …
Matched Description: … A derivative of procaine with less CNS action. …
Matched Salts cas: … 614-39-1 …
Matched Categories: … MATE 1 Substrates with a Narrow Therapeutic Index ... MATE 2 Substrates with a Narrow Therapeutic Index ... MATE 1 Substrates ... MATE 2 Substrates ... OCT2 Substrates with a Narrow Therapeutic Index …
Laropiprant
Laropiprant is an ingredient in the EMA-withdrawn product Pelzont.
Approved
Investigational
Withdrawn
Matched Iupac: … 2-[(3R)-4-[(4-chlorophenyl)methyl]-7-fluoro-5-methanesulfonyl-1H,2H,3H,4H-cyclopenta[b]indol-3-yl]acetic …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Linezolid
Linezolid is a synthetic antibiotic which is used for the treatment of infections caused by aerobic Gram-positive bacteria. Its effects are bacteriostatic against both enterococci and staphylococci and bactericidal against most isolates of streptococci. Linezolid exerts its antibacterial activity by inhibiting the initiation of bacterial protein synthesis - more specifically,...
Approved
Investigational
Matched Synonyms: … N-(((S)-3-(3-Fluoro-4-morpholinophenyl)-2-oxo-5-oxazolidinyl)methyl)acetamide …
Matched Iupac: … N-{[(5S)-3-[3-fluoro-4-(morpholin-4-yl)phenyl]-2-oxo-1,3-oxazolidin-5-yl]methyl}acetamide …
Matched Description: … Linezolid is a synthetic antibiotic which is used for the treatment of infections caused by aerobic Gram-positive ... [A233425] A second member of this class, [tedizolid], was approved by the FDA in 2014 and is considered …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Monoamine Oxidase A Inhibitors for interaction with Monoamine Oxidase A substrates …
Matched Products: … LINEZOLID B. BRAUN ... LIMEXID 2 MG/1 ML I.V. INFUZYON ICIN COZELTI ICEREN FLAKON, 1 ADET ... INFÜZYON ÇÖZELTISI,300 ML (1 TORBA) …
Matched Iupac: … N-{[(5S)-3-[3-fluoro-4-(morpholin-4-yl)phenyl]-2-oxo-1,3-oxazolidin-5-yl]methyl}acetamide …
Matched Description: … Linezolid is a synthetic antibiotic which is used for the treatment of infections caused by aerobic Gram-positive ... [A233425] A second member of this class, [tedizolid], was approved by the FDA in 2014 and is considered …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Monoamine Oxidase A Inhibitors for interaction with Monoamine Oxidase A substrates …
Matched Products: … LINEZOLID B. BRAUN ... LIMEXID 2 MG/1 ML I.V. INFUZYON ICIN COZELTI ICEREN FLAKON, 1 ADET ... INFÜZYON ÇÖZELTISI,300 ML (1 TORBA) …
Equine Botulinum Neurotoxin E Immune FAB2
Equine Botulinum Neurotoxin E Immune FAB2 is composed of a mixture of immune globulin fragments purified from plasma of horses that were previously immunized with botulinum toxin serotype E. It is intravenously administered for the treatment of symptomatic botulism following documented or suspected exposure to botulinum neurotoxin serotypes E in...
Approved
Experimental
Investigational
Matched Description: … Equine Botulinum Neurotoxin E Immune FAB2 is composed of a mixture of immune globulin fragments purified …
Equine Botulinum Neurotoxin C Immune FAB2
Equine Botulinum Neurotoxin C Immune FAB2 is composed of a mixture of immune globulin fragments purified from plasma of horses that were previously immunized with botulinum toxin serotype C. It is intravenously administered for the treatment of symptomatic botulism following documented or suspected exposure to botulinum neurotoxin serotypes C in...
Approved
Experimental
Investigational
Matched Description: … Equine Botulinum Neurotoxin C Immune FAB2 is composed of a mixture of immune globulin fragments purified …
Sofosbuvir
Sofosbuvir (tradename Sovaldi) is a direct acting antiviral medication used as part of combination therapy to treat chronic Hepatitis C, an infectious liver disease caused by infection with Hepatitis C Virus (HCV). HCV is a single-stranded RNA virus that is categorized into nine distinct genotypes, with genotype 1 being the...
Approved
Matched Synonyms: … S)-Isopropyl 2-((S)-(((2R,3R,4R,5R)-5-(2,4-dioxo-3,4- dihydropyrimidin-1(2H)-yl)-4-fluoro-3-hydroxy-4 ... -methyltetrahydrofuran-2-yl)methoxy)- (phenoxy)phosphorylamino)propanoate …
Matched Iupac: … propan-2-yl (2S)-2-{[(S)-{[(2R,3R,4R,5R)-5-(2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)-4-fluoro-3-hydroxy ... -4-methyloxolan-2-yl]methoxy}(phenoxy)phosphoryl]amino}propanoate …
Matched Description: … HCV is a single-stranded RNA virus that is categorized into nine distinct genotypes, with genotype 1 ... 2'-deoxy-2'-α-fluoro-β-C-methyluridine-5'-triphosphate (also known as GS-461203), which acts as a defective ... to treat chronic Hepatitis C, an infectious liver disease caused by infection with Hepatitis C Virus …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Hepatitis C Virus Nucleotide Analog NS5B Polymerase Inhibitor …
Matched Iupac: … propan-2-yl (2S)-2-{[(S)-{[(2R,3R,4R,5R)-5-(2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)-4-fluoro-3-hydroxy ... -4-methyloxolan-2-yl]methoxy}(phenoxy)phosphoryl]amino}propanoate …
Matched Description: … HCV is a single-stranded RNA virus that is categorized into nine distinct genotypes, with genotype 1 ... 2'-deoxy-2'-α-fluoro-β-C-methyluridine-5'-triphosphate (also known as GS-461203), which acts as a defective ... to treat chronic Hepatitis C, an infectious liver disease caused by infection with Hepatitis C Virus …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Hepatitis C Virus Nucleotide Analog NS5B Polymerase Inhibitor …
Vericiguat
Vericiguat is a direct stimulator of soluble guanylate cyclase (sGC) used in the management of systolic heart failure to reduce mortality and hospitalizations. A key component of the NO-sGC-cGMP signaling pathway that helps to regulate the cardiovascular system, sGC enzymes are intracellular enzymes found in vascular smooth muscle cells (amongst...
Approved
Investigational
Matched Iupac: … methyl N-(4,6-diamino-2-{5-fluoro-1-[(2-fluorophenyl)methyl]-1H-pyrazolo[3,4-b]pyridin-3-yl}pyrimidin …
Matched Description: … [A227458,A227488] Cyclic GMP acts as a second messenger, activating a number of downstream signaling ... [A227458] As a direct stimulator of sGC, vericiguat mitigates the need for a functional NO-sGC-cGMP axis ... Vericiguat is a direct stimulator of soluble guanylate cyclase (sGC) used in the management of systolic …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Description: … [A227458,A227488] Cyclic GMP acts as a second messenger, activating a number of downstream signaling ... [A227458] As a direct stimulator of sGC, vericiguat mitigates the need for a functional NO-sGC-cGMP axis ... Vericiguat is a direct stimulator of soluble guanylate cyclase (sGC) used in the management of systolic …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Vanadium
Approved
Experimental
Matched Mixtures name: … Advanced B & T Formula ... Extra Once A Day ... Maximum Once A Day …
Ferrous gluconate
Approved
Matched Synonyms: … Iron(2+) gluconate (1:2) ... D-gluconic acid, iron(2+) salt (2:1) …
Matched Iupac: … lambda2-iron(2+) bis((2R,3S,4R,5R)-2,3,4,5,6-pentahydroxyhexanoate) …
Matched Mixtures name: … Swical-energy-2 ... Vitamine Du Groupe B Plus Fer - Liq ... Vege 1 Daily Tab …
Matched Iupac: … lambda2-iron(2+) bis((2R,3S,4R,5R)-2,3,4,5,6-pentahydroxyhexanoate) …
Matched Mixtures name: … Swical-energy-2 ... Vitamine Du Groupe B Plus Fer - Liq ... Vege 1 Daily Tab …
Denileukin diftitox
A recombinant DNA-derived cytotoxic protein composed of the amino acid sequences for diphtheria toxin fragments A and B (Met 1-Thr 387)-His followed by the sequences for interleukin-2 (IL-2; Ala 1-Thr 133). It is produced in an E. coli expression system.
Approved
Investigational
Matched Synonyms: … Interleukin-2/diptheria toxin fusion protein …
Matched Description: … fragments A and B (Met 1-Thr 387)-His followed by the sequences for interleukin-2 (IL-2; Ala 1-Thr 133 ... A recombinant DNA-derived cytotoxic protein composed of the amino acid sequences for diphtheria toxin …
Matched Description: … fragments A and B (Met 1-Thr 387)-His followed by the sequences for interleukin-2 (IL-2; Ala 1-Thr 133 ... A recombinant DNA-derived cytotoxic protein composed of the amino acid sequences for diphtheria toxin …
Technetium Tc-99m mebrofenin
Technetium Tc 99m Mebrofenin is a diagnostic radiopharmaceutical composed of diisopropyl-iminodiacetic acid (DISIDA) attached to a technetium-99m ion. Following intravenous injection, single photon emission computer tomography (SPECT) imaging of the liver or gallbladder is performed using a gamma camera to detect the gamma rays emitted by the technetium-99m as it...
Approved
Matched Synonyms: … Bis(2-[[2-(3-bromo-2,4,6-trimethylanilino)-2-oxoethyl]-(carboxymethyl)amino]acetate) technetium …
Matched Iupac: … 2-({[(3-bromo-2,4,6-trimethylphenyl)carbamoyl]methyl}(carboxymethyl)amino)acetic acid technetium …
Matched Description: … acid (DISIDA) attached to a technetium-99m ion. ... Technetium Tc 99m Mebrofenin is a diagnostic radiopharmaceutical composed of diisopropyl-iminodiacetic ... photon emission computer tomography (SPECT) imaging of the liver or gallbladder is performed using a …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Iupac: … 2-({[(3-bromo-2,4,6-trimethylphenyl)carbamoyl]methyl}(carboxymethyl)amino)acetic acid technetium …
Matched Description: … acid (DISIDA) attached to a technetium-99m ion. ... Technetium Tc 99m Mebrofenin is a diagnostic radiopharmaceutical composed of diisopropyl-iminodiacetic ... photon emission computer tomography (SPECT) imaging of the liver or gallbladder is performed using a …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Didanosine
A dideoxynucleoside compound in which the 3'-hydroxy group on the sugar moiety has been replaced by a hydrogen. This modification prevents the formation of phosphodiester linkages which are needed for the completion of nucleic acid chains. Didanosine is a potent inhibitor of HIV replication, acting as a chain-terminator of viral...
Approved
Matched Synonyms: … 9-((2S,5R)-5-Hydroxymethyl-tetrahydro-furan-2-yl)-9H-purin-6-ol ... 9-((2R,5S)-5-(hydroxymethyl)-tetrahydrofuran-2-yl)-1H-purin-6(9H)-one ... 9-((2R,5S)-5-Hydroxymethyl-tetrahydro-furan-2-yl)-1,9-dihydro-purin-6-one …
Matched Iupac: … 9-[(2R,5S)-5-(hydroxymethyl)oxolan-2-yl]-6,9-dihydro-3H-purin-6-one …
Matched Description: … A dideoxynucleoside compound in which the 3'-hydroxy group on the sugar moiety has been replaced ... by a hydrogen. ... Didanosine is a potent inhibitor of HIV replication, acting as a chain-terminator of viral DNA by binding …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... Human Immunodeficiency Virus Nucleoside Analog Reverse Transcriptase Inhibitor …
Matched Iupac: … 9-[(2R,5S)-5-(hydroxymethyl)oxolan-2-yl]-6,9-dihydro-3H-purin-6-one …
Matched Description: … A dideoxynucleoside compound in which the 3'-hydroxy group on the sugar moiety has been replaced ... by a hydrogen. ... Didanosine is a potent inhibitor of HIV replication, acting as a chain-terminator of viral DNA by binding …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... Human Immunodeficiency Virus Nucleoside Analog Reverse Transcriptase Inhibitor …
Antilymphocyte immunoglobulin (horse)
Equine anti-thymocyte globulin is composed of purified gamma globulin containing primarily IgG against human thymus lymphocytes. It is formed by inoculating a horse with an antigen (human thymoyctes) which then induces the horse immune system's B-lymphocytes to produce IgG immunoglobulins specific for that antigen. The result is polyclonal IgG that...
Approved
Investigational
Matched Description: … system's B-lymphocytes to produce IgG immunoglobulins specific for that antigen. ... It is formed by inoculating a horse with an antigen (human thymoyctes) which then induces the horse immune ... Although the exact mechanism of action is unknown, equine anti-thymocyte globulin targets a variety of …
Levomilnacipran
Levomilnacipran is a selective serotonin and norepinephrine reuptake inhibitor (SNRI), although it is a more potent inhibitor of norepinephrine reuptake than serotonin reuptake.[A261181, A38560] Levomilnacipran is the more active 1S,2R-enantiomer in the racemate milnacipran.[A261181, L47956] Once administered, interconversion between levomilnacipran and its stereoisomer does not occur in humans. First approved...
Approved
Investigational
Matched Synonyms: … CYCLOPROPANECARBOXAMIDE, 2-(AMINOMETHYL)-N,N-DIETHYL-1-PHENYL-, (1S,2R)- …
Matched Iupac: … (1S,2R)-2-(aminomethyl)-N,N-diethyl-1-phenylcyclopropane-1-carboxamide …
Matched Description: … a more potent inhibitor of norepinephrine reuptake than serotonin reuptake. ... Levomilnacipran is a selective serotonin and norepinephrine reuptake inhibitor (SNRI), although it is ... [L47956] While levomilnacipran was previously investigated and proposed as a potential treatment for …
Matched Iupac: … (1S,2R)-2-(aminomethyl)-N,N-diethyl-1-phenylcyclopropane-1-carboxamide …
Matched Description: … a more potent inhibitor of norepinephrine reuptake than serotonin reuptake. ... Levomilnacipran is a selective serotonin and norepinephrine reuptake inhibitor (SNRI), although it is ... [L47956] While levomilnacipran was previously investigated and proposed as a potential treatment for …
Mogamulizumab
Mogamulizumab is a humanized monoclonal antibody (mAb) directed against CC chemokine receptor 4 (CCR4) for the treatment of Mycosis Fungoides (MF) and Sézary Syndrome (SS), the most common subtypes of cutaneous T-cell lymphoma. Cutaneous T-cell lymphomas occur when certain white blood cells, called T cells, become cancerous; these cancers typically...
Approved
Investigational
Matched Description: … [L4170]
On August 8 2018, the U.S. ... Mogamulizumab is a humanized monoclonal antibody (mAb) directed against CC chemokine receptor 4 (CCR4 …
Lovastatin
Lovastatin, also known as the brand name product Mevacor, is a lipid-lowering drug and fungal metabolite derived synthetically from a fermentation product of Aspergillus terreus. Originally named Mevinolin, lovastatin belongs to the statin class of medications, which are used to lower the risk of cardiovascular disease and manage abnormal lipid...
Approved
Investigational
Matched Synonyms: … -2-yl)ethyl)-1-naphthalenyl (S)-2-methyl-butyrate ... 2β,6α-dimethyl-8alpha-(2-methyl-1-oxobutoxy)-mevinic acid lactone ... (1S,3R,7S,8S,8aR)-1,2,3,7,8,8a-hexahydro-3,7-dimethyl-8-(2-(2R,4R)-(tetrahydro-4-hydroxy-6-oxo-2H-pyran …
Matched Iupac: … -1-yl (2S)-2-methylbutanoate ... (1S,3R,7S,8S,8aR)-8-{2-[(2R,4R)-4-hydroxy-6-oxooxan-2-yl]ethyl}-3,7-dimethyl-1,2,3,7,8,8a-hexahydronaphthalen …
Matched Description: … moderate to high risk of development of CVD, such as those with Type 2 Diabetes. ... (heart attack, stroke, coronary revascularization, and coronary death) for every 1 mmol/L reduction ... derived synthetically from a fermentation product of _Aspergillus terreus_. …
Matched Iupac: … -1-yl (2S)-2-methylbutanoate ... (1S,3R,7S,8S,8aR)-8-{2-[(2R,4R)-4-hydroxy-6-oxooxan-2-yl]ethyl}-3,7-dimethyl-1,2,3,7,8,8a-hexahydronaphthalen …
Matched Description: … moderate to high risk of development of CVD, such as those with Type 2 Diabetes. ... (heart attack, stroke, coronary revascularization, and coronary death) for every 1 mmol/L reduction ... derived synthetically from a fermentation product of _Aspergillus terreus_. …
Selenious acid
Selenious acid is the acid form of sodium selenite, a form of selenium .
Selenium is an essential trace element and antioxidant. It is a cofactor metabolic enzyme regulation. It also plays an important role in maintaining the general health of tissue and muscle and has antioxidant properties. Selenium is...
Approved
Investigational
Matched Description: … It is a cofactor metabolic enzyme regulation. ... Selenious acid is the acid form of sodium selenite, a form of selenium [L1910]. ... Selenium is a component of glutathione peroxidase enzyme, which protects cell components from oxidative …
Matched Salts cas: … 26970-82-1 …
Matched Mixtures name: … Vege 1 Daily Tab ... Tricare Prenatal 2-part Daily Prenatal Vitamin System ... Addamel N …
Matched Products: … Selenase 100 Mikrogramm/2 ml - Lösung zum Einnehmen …
Matched Salts cas: … 26970-82-1 …
Matched Mixtures name: … Vege 1 Daily Tab ... Tricare Prenatal 2-part Daily Prenatal Vitamin System ... Addamel N …
Matched Products: … Selenase 100 Mikrogramm/2 ml - Lösung zum Einnehmen …
Metaraminol
An adrenergic agonist that acts predominantly at alpha adrenergic receptors and also stimulates the release of norepinephrine. It has been used primarily as a vasoconstrictor in the treatment of hypotension.
Approved
Investigational
Matched Synonyms: … 1-(m-Hydroxyphenyl)-2-amino-1-propanol ... 2-Amino-1-(m-hydroxyphenyl)-1-propanol ... alpha-(1-Aminoethyl)-3-hydroxybenzenemethanol …
Matched Iupac: … 3-[(1R,2S)-2-amino-1-hydroxypropyl]phenol …
Matched Description: … It has been used primarily as a vasoconstrictor in the treatment of hypotension. …
Matched Categories: … Adrenergic alpha-1 Receptor Agonists …
Matched Iupac: … 3-[(1R,2S)-2-amino-1-hydroxypropyl]phenol …
Matched Description: … It has been used primarily as a vasoconstrictor in the treatment of hypotension. …
Matched Categories: … Adrenergic alpha-1 Receptor Agonists …
Octocrylene
Octocrylene is a compound often used as an additive in sun screen, and is thought to have skin moisturizing effects because of its emollient properties. What makes this chemical such a popular additive to sun block, is its ability to neutralize UV radiation dissipated by sunlight, and to minimize skin...
Approved
Investigational
Matched Iupac: … 2-ethylhexyl 2-cyano-3,3-diphenylprop-2-enoate …
Matched Description: … Octocrylene is a compound often used as an additive in sun screen, and is thought to have skin moisturizing ... What makes this chemical such a popular additive to sun block, is its ability to neutralize UV radiation ... However, the use of this chemical doesn’t just stop with sunscreen for face and arms, but can extend to a …
Matched Mixtures name: … H-E-B Solutions Sunscreen Coconut SPF 50 Continuous ... H-E-B Dead Sea Organics Protect and Perfect Day Broad Spectrum SPF15 ... Intensive 3-IN-1 Day Cream SPF 30 …
Matched Description: … Octocrylene is a compound often used as an additive in sun screen, and is thought to have skin moisturizing ... What makes this chemical such a popular additive to sun block, is its ability to neutralize UV radiation ... However, the use of this chemical doesn’t just stop with sunscreen for face and arms, but can extend to a …
Matched Mixtures name: … H-E-B Solutions Sunscreen Coconut SPF 50 Continuous ... H-E-B Dead Sea Organics Protect and Perfect Day Broad Spectrum SPF15 ... Intensive 3-IN-1 Day Cream SPF 30 …
Torasemide
Torasemide is a high-ceiling loop diuretic. Structurally, it is a pyridine-sulfonylurea used as an antihypertensive agent. Torasemide was first approved for clinical use by the FDA in 1993.
Approved
Matched Synonyms: … N-(((1-Methylethyl)amino)carbonyl)-4-((3-methylphenyl)amino)-3-pyridinesulfonamide ... 1-Isopropyl-3-((4-m-toluidino-3-pyridyl)sulfonyl)urea …
Matched Iupac: … 1-({4-[(3-methylphenyl)amino]pyridin-3-yl}sulfonyl)-3-(propan-2-yl)urea …
Matched Description: … Torasemide is a high-ceiling loop diuretic. ... [A174463] Structurally, it is a pyridine-sulfonylurea used as an antihypertensive agent. …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Iupac: … 1-({4-[(3-methylphenyl)amino]pyridin-3-yl}sulfonyl)-3-(propan-2-yl)urea …
Matched Description: … Torasemide is a high-ceiling loop diuretic. ... [A174463] Structurally, it is a pyridine-sulfonylurea used as an antihypertensive agent. …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Omadacycline
Omadacycline has been used in trials studying the treatment of Bacterial Pneumonia, Bacterial Infections, Community-Acquired Infections, and Skin Structures and Soft Tissue Infections. Omadacycline represents a significant advance over the well-known tetracycline family, and has been shown to be highly effective in animal models at treating increasingly problematic, clinically prevalent...
Approved
Investigational
Matched Iupac: … dimethylpropyl)amino]methyl}-3,10,12,12a-tetrahydroxy-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2- …
Matched Description: … Omadacycline represents a significant advance over the well-known tetracycline family, and has been shown …
Matched Description: … Omadacycline represents a significant advance over the well-known tetracycline family, and has been shown …
Treprostinil
Treprostinil is a stable tricyclic analogue of prostacyclin that promotes the vasodilation of pulmonary and systemic arterial vascular beds and the inhibition of platelet aggregation.[L41855,L41860,L41865] It reduces symptoms in patients with pulmonary arterial hypertension (PAH) and pulmonary hypertension associated with interstitial lung disease.[L41855,L41860] The first agent approved for the treatment...
Approved
Investigational
Matched Iupac: … 2-{[(1R,2R,3aS,9aS)-2-hydroxy-1-[(3S)-3-hydroxyoctyl]-1H,2H,3H,3aH,4H,9H,9aH-cyclopenta[b]naphthalen- …
Matched Description: … The first generic form of treprostinil became available in 2019.[A248775] ... However, the use of epoprostenol is limited due to its short half-life (3-5 min) and instability at room ... Treprostinil is a stable tricyclic analogue of prostacyclin[A248770] that promotes the vasodilation of …
Matched Products: … REMODULIN 1 mg/ml Infusionslösung ... REMODULIN ® INYECCIÓN 1 MG/ML ... Treposa 1 mg/ml Infusionslösung …
Matched Description: … The first generic form of treprostinil became available in 2019.[A248775] ... However, the use of epoprostenol is limited due to its short half-life (3-5 min) and instability at room ... Treprostinil is a stable tricyclic analogue of prostacyclin[A248770] that promotes the vasodilation of …
Matched Products: … REMODULIN 1 mg/ml Infusionslösung ... REMODULIN ® INYECCIÓN 1 MG/ML ... Treposa 1 mg/ml Infusionslösung …
Labetalol
Labetalol is a racemic mixture of 2 diastereoisomers where dilevalol, the R,R' stereoisomer, makes up 25% of the mixture. Labetalol is formulated as an injection or tablets to treat hypertension.[L7727,L7730]
Labetalol was granted FDA approval on 1 August 1984.
Approved
Matched Synonyms: … 5-(1-Hydroxy-2-(1-methyl-3-phenylpropylamino)ethyl)salicylamide ... 3-Carboxamido-4-hydroxy-alpha-((1-methyl-3-phenylpropylamino)methyl)benzyl alcohol …
Matched Iupac: … 2-hydroxy-5-{1-hydroxy-2-[(4-phenylbutan-2-yl)amino]ethyl}benzamide …
Matched Description: … Labetalol is a racemic mixture of 2 diastereoisomers where dilevalol, the R,R' stereoisomer, makes up ... [L7727,L7730] Labetalol was granted FDA approval on 1 August 1984.[L7724] …
Matched Categories: … Peripheral alpha-1 blockers ... Adrenergic alpha-1 Receptor Antagonists …
Matched Iupac: … 2-hydroxy-5-{1-hydroxy-2-[(4-phenylbutan-2-yl)amino]ethyl}benzamide …
Matched Description: … Labetalol is a racemic mixture of 2 diastereoisomers where dilevalol, the R,R' stereoisomer, makes up ... [L7727,L7730] Labetalol was granted FDA approval on 1 August 1984.[L7724] …
Matched Categories: … Peripheral alpha-1 blockers ... Adrenergic alpha-1 Receptor Antagonists …
Displaying drugs 626 - 650 of 6317 in total