Displaying drugs 626 - 650 of 2927 in total
Methotrexate
Methotrexate is a folate derivative that inhibits several enzymes responsible for nucleotide synthesis. This inhibition leads to suppression of inflammation as well as prevention of cell division. Because of these effects, methotrexate is often used to treat inflammation caused by arthritis or to control cell division in neoplastic diseases such...
Approved
Matched Synonyms: … N-[4-[[(2,4-diamino-6-pteridinyl)methyl]methylamino]benzoyl]-L-glutamic acid ... 4-amino-10-methylfolic acid ... 4-amino-N(10)-methylpteroylglutamic acid …
Matched Iupac: … -[(4-{[(4-amino-2-imino-2,3-dihydropteridin-6-yl)methyl](methyl)amino}phenyl)formamido]pentanedioic acid …
Matched Description: … inflammation caused by arthritis or to control cell division in neoplastic diseases such as breast cancer and ... Due to the toxic effects of methotrexate, it is indicated for treatment of some forms of arthritis and …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Folic Acid Analogues ... Folic Acid Antagonists ... Nucleic Acid Synthesis Inhibitors …
Matched Iupac: … -[(4-{[(4-amino-2-imino-2,3-dihydropteridin-6-yl)methyl](methyl)amino}phenyl)formamido]pentanedioic acid …
Matched Description: … inflammation caused by arthritis or to control cell division in neoplastic diseases such as breast cancer and ... Due to the toxic effects of methotrexate, it is indicated for treatment of some forms of arthritis and …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Folic Acid Analogues ... Folic Acid Antagonists ... Nucleic Acid Synthesis Inhibitors …
Arginine PCA
Experimental
Matched Synonyms: … Arginine pidolate ... Arginine pyroglutamate ... L-arginine L-2-pyrrolidone-5-carboxylate …
Matched Name: … Arginine PCA …
Matched Iupac: … (2S)-2-amino-5-carbamimidamidopentanoic acid; (2S)-5-oxopyrrolidine-2-carboxylic acid …
Matched Name: … Arginine PCA …
Matched Iupac: … (2S)-2-amino-5-carbamimidamidopentanoic acid; (2S)-5-oxopyrrolidine-2-carboxylic acid …
Bufexamac
Bufexamac is a non-steroidal anti-inflammatory drug (NSAID) under the market name Droxaryl, Malipuran, Paraderm and Parfenac. It is typically administered topically for the treatment of subacute and chronic eczema of the skin, including atopic eczema and other inflammatory dermatoses, as well as sunburn and other minor burns, and itching. It...
Approved
Withdrawn
Matched Synonyms: … Bufexamic acid ... 2-(p-Butoxyphenyl)-acetohydroxamic acid ... 4-Butoxyphenylacetohydroxamic acid …
Matched Description: … and itching. ... including atopic eczema and other inflammatory dermatoses, as well as sunburn and other minor burns, ... a non-steroidal anti-inflammatory drug (NSAID) under the market name Droxaryl, Malipuran, Paraderm and …
Matched Categories: … Acetic Acid Derivatives and Related Substances ... Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids ... Topical Products for Joint and Muscular Pain ... Hydroxy Acids …
Matched Description: … and itching. ... including atopic eczema and other inflammatory dermatoses, as well as sunburn and other minor burns, ... a non-steroidal anti-inflammatory drug (NSAID) under the market name Droxaryl, Malipuran, Paraderm and …
Matched Categories: … Acetic Acid Derivatives and Related Substances ... Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids ... Topical Products for Joint and Muscular Pain ... Hydroxy Acids …
4-Nitrophenyl (3S)-3-({N-[(benzyloxy)carbonyl]-L-phenylalanyl}amino)-5-phenyl-1-pentanesulfonate
Experimental
Matched Synonyms: … 3-[N-[Benzyloxycarbonyl]-phenylalaninyl-amino]-5-phenyl-pentane-1-sulfonic acid 4-nitro-phenyl ester …
(6R)-Folinic acid
Experimental
Matched Synonyms: … L-Glutamic acid, N-[4-[[[(6R)-2-amino-5-formyl-3,4,5,6,7,8-hexahydro-4-oxo-6-pteridinyl]methyl]amino] ... acid ... (6R,2'S)-Folinic acid …
Matched Name: … (6R)-Folinic acid …
Matched Iupac: … -amino-5-formyl-4-oxo-1,4,5,6,7,8-hexahydropteridin-6-yl]methyl}amino)phenyl]formamido}pentanedioic acid …
Matched Categories: … Folic Acid and Derivatives …
Matched Name: … (6R)-Folinic acid …
Matched Iupac: … -amino-5-formyl-4-oxo-1,4,5,6,7,8-hexahydropteridin-6-yl]methyl}amino)phenyl]formamido}pentanedioic acid …
Matched Categories: … Folic Acid and Derivatives …
Arginine aspartate
Experimental
Matched Synonyms: … Arginine L-aspartate ... L-Arginine aspartate ... L-Arginine-L-aspartate …
Matched Name: … Arginine aspartate …
Matched Iupac: … (2S)-2-amino-5-carbamimidamidopentanoic acid; (2S)-2-aminobutanedioic acid …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids, Acidic ... Amino Acids ... Amino Acids, Basic ... Amino Acids, Diamino …
Matched Name: … Arginine aspartate …
Matched Iupac: … (2S)-2-amino-5-carbamimidamidopentanoic acid; (2S)-2-aminobutanedioic acid …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids, Acidic ... Amino Acids ... Amino Acids, Basic ... Amino Acids, Diamino …
Aminopterin
Aminopterin is an amino derivative of folic acid, which was once used as an antineoplastic agent in the treatment of pediatric leukemia. In the 1950's its production was discontinued in favor of methotrexate, which is less potent but less toxic. Off label, aminopterin has also been used in the treatment...
Investigational
Withdrawn
Matched Synonyms: … N-(4-(((2,4-diamino-6-pteridinyl)methyl)amino)benzoyl)-L-glutamic acid ... 4-aminofolic acid ... 4-aminopteroylglutamic acid …
Matched Iupac: … (2S)-2-[(4-{[(2,4-diaminopteridin-6-yl)methyl]amino}phenyl)formamido]pentanedioic acid …
Matched Description: … Clinicians need to be aware of the characteristic teratologic effects of aminopterin and methotrexate ... Aminopterin is an amino derivative of folic acid, which was once used as an antineoplastic agent in the …
Matched Categories: … Folic Acid Antagonists …
Matched Iupac: … (2S)-2-[(4-{[(2,4-diaminopteridin-6-yl)methyl]amino}phenyl)formamido]pentanedioic acid …
Matched Description: … Clinicians need to be aware of the characteristic teratologic effects of aminopterin and methotrexate ... Aminopterin is an amino derivative of folic acid, which was once used as an antineoplastic agent in the …
Matched Categories: … Folic Acid Antagonists …
Diphthamide
Experimental
Matched Synonyms: … 2-(3-Carboxyamido-3-(Trimethylammonio)Propyl)Histidine …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids ... Amino Acids, Cyclic …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids ... Amino Acids, Cyclic …
Betaine
Betaine is a methyl group donor that functions in the normal metabolic cycle of methionine. It is a naturally occurring choline derivative commonly ingested through diet, with a role in regulating cellular hydration and maintaining cell function.[A252235,A252240] Homocystinuria is an inherited disorder that leads to the accumulation of homocysteine in...
Approved
Investigational
Nutraceutical
Matched Synonyms: … Acidol ... Glycine betaine ... 2-(Trimethylammonio)Acetate …
Matched Iupac: … 2-(trimethylazaniumyl)acetate …
Matched Description: … occurring choline derivative commonly ingested through diet, with a role in regulating cellular hydration and ... A252240] Homocystinuria is an inherited disorder that leads to the accumulation of homocysteine in plasma and ... levels, patients can be treated with vitamin B6 ([pyridoxine]), vitamin B12 ([cobalamin]), [folate] and …
Matched Mixtures name: … Glutamic Acid Pepsin and Betaine Tablets ... Glutamic Acid HCl Betaine HCl W Pepsin ... Betaine HCl and Pepsin …
Matched Categories: … Amino Acids and Derivatives ... Alimentary Tract and Metabolism ... Acid Preparations …
Matched Iupac: … 2-(trimethylazaniumyl)acetate …
Matched Description: … occurring choline derivative commonly ingested through diet, with a role in regulating cellular hydration and ... A252240] Homocystinuria is an inherited disorder that leads to the accumulation of homocysteine in plasma and ... levels, patients can be treated with vitamin B6 ([pyridoxine]), vitamin B12 ([cobalamin]), [folate] and …
Matched Mixtures name: … Glutamic Acid Pepsin and Betaine Tablets ... Glutamic Acid HCl Betaine HCl W Pepsin ... Betaine HCl and Pepsin …
Matched Categories: … Amino Acids and Derivatives ... Alimentary Tract and Metabolism ... Acid Preparations …
Procaine benzylpenicillin
Procaine benzylpenicillin (INN), also known as procaine G penicillin, is an injectable antiobiotic. It is a poorly soluble salt form of penicillin which is a combination of naturally occuring benzylpenicillin (penicillin G) and the local anaesthetic agent procaine in equimolar amounts. Procaine benzylpenicillin is administered by deep intramuscular injection. It...
Approved
Vet approved
Matched Synonyms: … Penicillin G procaine …
Matched Name: … Procaine benzylpenicillin …
Matched Iupac: … (2S,5R,6R)-3,3-dimethyl-7-oxo-6-(2-phenylacetamido)-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid …
Matched Description: … It is slowly absorbed and hydrolyzed to benzylpenicillin. ... salt form of penicillin which is a combination of naturally occuring benzylpenicillin (penicillin G) and ... This combination is aimed at reducing the pain and discomfort associated with a large intramuscular injection …
Matched Categories: … Acids, Carbocyclic ... procaine benzylpenicillin ... Carboxylic Acids …
Matched Products: … Penicillin G Procaine ... PROCAINE BENZYLPENICILLIN ... PROCAINE BENZYL PENICILLIN …
Matched Name: … Procaine benzylpenicillin …
Matched Iupac: … (2S,5R,6R)-3,3-dimethyl-7-oxo-6-(2-phenylacetamido)-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid …
Matched Description: … It is slowly absorbed and hydrolyzed to benzylpenicillin. ... salt form of penicillin which is a combination of naturally occuring benzylpenicillin (penicillin G) and ... This combination is aimed at reducing the pain and discomfort associated with a large intramuscular injection …
Matched Categories: … Acids, Carbocyclic ... procaine benzylpenicillin ... Carboxylic Acids …
Matched Products: … Penicillin G Procaine ... PROCAINE BENZYLPENICILLIN ... PROCAINE BENZYL PENICILLIN …
DS-1211
DS-1211 is a potent and selective novel small molecule tissue-nonspecific alkaline phosphatase (TNAP) inhibitor.
Investigational
Matched Synonyms: … N-Acetyl-D-leucine ... N-Acetyl-R-leucine ... D-leucine, N-acetyl- …
Matched Iupac: … (2R)-2-acetamido-4-methylpentanoic acid …
Matched Description: … DS-1211 is a potent and selective novel small molecule tissue-nonspecific alkaline phosphatase (TNAP) …
Matched Iupac: … (2R)-2-acetamido-4-methylpentanoic acid …
Matched Description: … DS-1211 is a potent and selective novel small molecule tissue-nonspecific alkaline phosphatase (TNAP) …
Iodoxamic acid
Radiopaque medium used in the diagnosis of gall bladder & bile duct diseases, usually as meglumine salt.
Experimental
Matched Synonyms: … Iodoxamic acid ... Acidum iodoxamicum …
Matched Name: … Iodoxamic acid …
Matched Iupac: … 3-carboxy-2,4,6-triiodophenyl)carbamoyl]-3,6,9,12-tetraoxapentadecan-15-amido}-2,4,6-triiodobenzoic acid …
Matched Categories: … Acids, Carbocyclic ... Carboxylic Acids ... iodoxamic acid …
Matched Name: … Iodoxamic acid …
Matched Iupac: … 3-carboxy-2,4,6-triiodophenyl)carbamoyl]-3,6,9,12-tetraoxapentadecan-15-amido}-2,4,6-triiodobenzoic acid …
Matched Categories: … Acids, Carbocyclic ... Carboxylic Acids ... iodoxamic acid …
Kynurenine
Experimental
Matched Synonyms: … (2S)-2-amino-4-(2-aminophenyl)-4-oxobutanoic acid ... 3-Anthraniloyl-L-alanine …
Matched Iupac: … (2S)-2-amino-4-(2-aminophenyl)-4-oxobutanoic acid …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids …
Matched Iupac: … (2S)-2-amino-4-(2-aminophenyl)-4-oxobutanoic acid …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids …
Dipivefrin
Dipivefrin is a prodrug of adrenaline, which is used to treat glaucoma. It is available as ophthalmic solution (eye drops).
Approved
Matched Categories: … Antiglaucoma Preparations and Miotics …
Matched Products: … Propine ... PROPINE ... Propine Liq 0.1% …
Matched Products: … Propine ... PROPINE ... Propine Liq 0.1% …
Metenkefalin
Metenkefalin is an endogenous opioid and beta-endorphin. It has been shown to reduce chromosomal abberations in patients with multiple sclerosis. Metenkefalin, along with tridecactide, are under investigation as an immunomodulatory therapy for moderate to severe COVID-19.[L13874,L13877]
Investigational
Matched Synonyms: … Methionine Enkephalin …
Matched Iupac: … 3-(4-hydroxyphenyl)propanamido]acetamido}acetamido)-3-phenylpropanamido]-4-(methylsulfanyl)butanoic acid …
Matched Description: … Metenkefalin is an endogenous opioid and beta-endorphin. …
Matched Salts name: … Metenkefalin acetate …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Enkephalin, Methionine …
Matched Iupac: … 3-(4-hydroxyphenyl)propanamido]acetamido}acetamido)-3-phenylpropanamido]-4-(methylsulfanyl)butanoic acid …
Matched Description: … Metenkefalin is an endogenous opioid and beta-endorphin. …
Matched Salts name: … Metenkefalin acetate …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Enkephalin, Methionine …
Levoleucovorin
Levoleucovorin is the enantiomerically active form of Folinic Acid (also known as 5-formyl tetrahydrofolic acid or leucovorin). Commercially available leucovorin is composed of a 1:1 racemic mixture of the dextrorotary and levorotary isomers, while levoleucovorin contains only the pharmacologically active levo-isomer. In vitro, the levo-isomer has been shown to be...
Approved
Investigational
Matched Synonyms: … N-[4-({[(6S)-2-amino-5-formyl-4-oxo-1,4,5,6,7,8-hexahydropteridin-6-yl]methyl}amino)benzoyl]-L-glutamic ... acid ... L-Folinic acid …
Matched Iupac: … -amino-5-formyl-4-oxo-1,4,5,6,7,8-hexahydropteridin-6-yl]methyl}amino)phenyl]formamido}pentanedioic acid …
Matched Description: … and methionine before incorporation into DNA or protein. ... This important pathway, which is required for de novo synthesis of nucleic acids and amino acids, is ... acid or leucovorin). …
Matched Categories: … Folic Acid and Derivatives ... Enzymes and Coenzymes ... Folic Acid Analogues …
Matched Iupac: … -amino-5-formyl-4-oxo-1,4,5,6,7,8-hexahydropteridin-6-yl]methyl}amino)phenyl]formamido}pentanedioic acid …
Matched Description: … and methionine before incorporation into DNA or protein. ... This important pathway, which is required for de novo synthesis of nucleic acids and amino acids, is ... acid or leucovorin). …
Matched Categories: … Folic Acid and Derivatives ... Enzymes and Coenzymes ... Folic Acid Analogues …
3-nitro-L-tyrosine
Experimental
Matched Synonyms: … (2S)-2-amino-3-(4-hydroxy-3-nitrophenyl)propanoic acid ... 3-Nitro-L-tyrosine …
Matched Name: … 3-nitro-L-tyrosine …
Matched Iupac: … (2S)-2-amino-3-(4-hydroxy-3-nitrophenyl)propanoic acid …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids ... Amino Acids, Cyclic ... Amino Acids, Aromatic …
Matched Name: … 3-nitro-L-tyrosine …
Matched Iupac: … (2S)-2-amino-3-(4-hydroxy-3-nitrophenyl)propanoic acid …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids ... Amino Acids, Cyclic ... Amino Acids, Aromatic …
N(2)-succinyl-L-arginine
Experimental
Matched Synonyms: … Succinyl-arginine ... N2-Succinyl-L-arginine …
Matched Name: … N(2)-succinyl-L-arginine …
Matched Iupac: … (2S)-5-carbamimidamido-2-[(3-carboxy-1-hydroxypropylidene)amino]pentanoic acid …
Matched Name: … N(2)-succinyl-L-arginine …
Matched Iupac: … (2S)-5-carbamimidamido-2-[(3-carboxy-1-hydroxypropylidene)amino]pentanoic acid …
LSTA1
Investigational
Matched Synonyms: … Internalized-arginylglycylaspartic acid cyclic peptide ... -aspartyl-l-lysylglycyl-l-prolyl-l-.alpha.-aspartyl-, cyclic (1->9)-disulfide …
Linoleic acid
Approved
Experimental
Matched Synonyms: … Linolic acid ... acide linoléique ... acide cis-linoléique …
Matched Name: … Linoleic acid …
Matched Iupac: … (9Z,12Z)-octadeca-9,12-dienoic acid …
Matched Categories: … Fatty Acids ... Linoleic Acids ... Fatty Acids, Omega-6 ... Fatty Acids, Essential ... Fatty Acids, Unsaturated …
Matched Name: … Linoleic acid …
Matched Iupac: … (9Z,12Z)-octadeca-9,12-dienoic acid …
Matched Categories: … Fatty Acids ... Linoleic Acids ... Fatty Acids, Omega-6 ... Fatty Acids, Essential ... Fatty Acids, Unsaturated …
Folitixorin
Investigational
Matched Synonyms: … L-glutamic acid, n-(4-(3-amino-1,2,5,6,6a,7-hexahydro-1-oxoimidazo(1,5-f)pteridin-8(9h)-yl)benzoyl)- ... 5,10-methylene-(6rs)-tetrahydrofolic acid ... 5,10-methylenetetrahydrofolic acid …
Matched Iupac: … 4-{3-amino-1-oxo-1H,2H,5H,6H,6aH,7H,8H,9H-imidazo[1,5-f]pteridin-8-yl}phenyl)formamido]pentanedioic acid …
Matched Categories: … Enzymes and Coenzymes …
Matched Iupac: … 4-{3-amino-1-oxo-1H,2H,5H,6H,6aH,7H,8H,9H-imidazo[1,5-f]pteridin-8-yl}phenyl)formamido]pentanedioic acid …
Matched Categories: … Enzymes and Coenzymes …
Metyrosine
An inhibitor of the enzyme tyrosine 3-monooxygenase, and consequently of the synthesis of catecholamines. It is used to control the symptoms of excessive sympathetic stimulation in patients with pheochromocytoma. (Martindale, The Extra Pharmacopoeia, 30th ed)
Approved
Matched Synonyms: … α-methyl-p-tyrosine ... (–)-α-methyl-L-tyrosine ... α-methyl-L-p-tyrosine …
Matched Iupac: … (2S)-2-amino-3-(4-hydroxyphenyl)-2-methylpropanoic acid …
Matched Description: … An inhibitor of the enzyme tyrosine 3-monooxygenase, and consequently of the synthesis of catecholamines …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Tyrosine Hydroxylase Inhibitors ... Amino Acids ... Amino Acids, Cyclic ... Amino Acids, Aromatic …
Matched Iupac: … (2S)-2-amino-3-(4-hydroxyphenyl)-2-methylpropanoic acid …
Matched Description: … An inhibitor of the enzyme tyrosine 3-monooxygenase, and consequently of the synthesis of catecholamines …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Tyrosine Hydroxylase Inhibitors ... Amino Acids ... Amino Acids, Cyclic ... Amino Acids, Aromatic …
Dexfosfoserine
The phosphoric acid ester of serine.
Experimental
Matched Synonyms: … Serine phosphate …
Matched Iupac: … (2S)-2-amino-3-(phosphonooxy)propanoic acid …
Matched Description: … The phosphoric acid ester of serine. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids ... Amino Acids, Neutral ... Phosphoamino Acids …
Matched Iupac: … (2S)-2-amino-3-(phosphonooxy)propanoic acid …
Matched Description: … The phosphoric acid ester of serine. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids ... Amino Acids, Neutral ... Phosphoamino Acids …
Fumaric acid
Investigational
Matched Synonyms: … Fumaric acid ... Fumaricum acidum ... (2E)-2-butenedioic acid …
Matched Name: … Fumaric acid …
Matched Iupac: … (2E)-but-2-enedioic acid …
Matched Categories: … Acids, Acyclic ... fumaric acid ... Carboxylic Acids ... Dicarboxylic Acids …
Matched Name: … Fumaric acid …
Matched Iupac: … (2E)-but-2-enedioic acid …
Matched Categories: … Acids, Acyclic ... fumaric acid ... Carboxylic Acids ... Dicarboxylic Acids …
Phosphatidyl serine
Phosphatidyl serine (PS) is a phospholipid nutrient found in fish, green leafy vegetables, soybeans and rice, and is essential for the normal functioning of neuronal cell membranes and activates Protein kinase C (PKC) which has been shown to be involved in memory function. In apoptosis, phosphatidyl serine is transferred to...
Investigational
Nutraceutical
Matched Synonyms: … Phosphatidyl serine …
Matched Name: … Phosphatidyl serine …
Matched Iupac: … (2S)-2-amino-3-({[(2R)-2,3-bis(octadecanoyloxy)propoxy](hydroxy)phosphoryl}oxy)propanoic acid …
Matched Description: … Phosphatidyl serine (PS) is a phospholipid nutrient found in fish, green leafy vegetables, soybeans and ... rice, and is essential for the normal functioning of neuronal cell membranes and activates Protein kinase ... PS has been investigated in a small number of double-blind placebo trials and has been shown to increase …
Matched Categories: … Phosphatidic Acids …
Matched Name: … Phosphatidyl serine …
Matched Iupac: … (2S)-2-amino-3-({[(2R)-2,3-bis(octadecanoyloxy)propoxy](hydroxy)phosphoryl}oxy)propanoic acid …
Matched Description: … Phosphatidyl serine (PS) is a phospholipid nutrient found in fish, green leafy vegetables, soybeans and ... rice, and is essential for the normal functioning of neuronal cell membranes and activates Protein kinase ... PS has been investigated in a small number of double-blind placebo trials and has been shown to increase …
Matched Categories: … Phosphatidic Acids …
Displaying drugs 626 - 650 of 2927 in total