Displaying drugs 6576 - 6600 of 8133 in total
Nivocasan
Nivocasan has been used in trials studying the treatment of HCV Infection and Nonalcoholic Steatohepatitis.
Investigational
Matched Iupac: … (5R)-N-[(2S,3S)-2-(fluoromethyl)-2-hydroxy-5-oxooxolan-3-yl]-3-(isoquinolin-1-yl)-5-(propan-2-yl)-4,5 ... -dihydro-1,2-oxazole-5-carboxamide …
5-fluorotryptophan
5-fluorotryptophan can be used as substrate analogue to study enzyme mechanisms by NMR spectroscopy.
Experimental
Matched Synonyms: … 5-fluoro-L-tryptophan ... L-5-fluorotryptophan …
Matched Name: … 5-fluorotryptophan …
Matched Iupac: … (2S)-2-amino-3-(5-fluoro-1H-indol-3-yl)propanoic acid …
Matched Description: … 5-fluorotryptophan can be used as substrate analogue to study enzyme mechanisms by NMR spectroscopy. …
Matched Name: … 5-fluorotryptophan …
Matched Iupac: … (2S)-2-amino-3-(5-fluoro-1H-indol-3-yl)propanoic acid …
Matched Description: … 5-fluorotryptophan can be used as substrate analogue to study enzyme mechanisms by NMR spectroscopy. …
beta-D-Ribose-5-phosphate
Experimental
Matched Synonyms: … β-D-ribofuranose 5-phosphate ... 5-O-phosphono-β-D-ribofuranose ... 5-O-phosphono-beta-D-ribofuranose …
Matched Name: … beta-D-Ribose-5-phosphate …
Matched Name: … beta-D-Ribose-5-phosphate …
N-acetyl-beta-neuraminic acid
An N-acyl derivative of neuraminic acid. N-acetylneuraminic acid occurs in many polysaccharides, glycoproteins, and glycolipids in animals and bacteria. (From Dorland, 28th ed, p1518)
Experimental
Matched Iupac: … (2S,4S,5R,6R)-5-acetamido-2,4-dihydroxy-6-[(1R,2R)-1,2,3-trihydroxypropyl]oxane-2-carboxylic acid …
5-Nitroindazole
Experimental
Matched Synonyms: … 5-Nitro-1H-indazole …
Matched Name: … 5-Nitroindazole …
Matched Iupac: … 5-nitro-1H-indazole …
Matched Name: … 5-Nitroindazole …
Matched Iupac: … 5-nitro-1H-indazole …
N-(2-hydroxy-1,1-dimethylethyl)-1-methyl-3-(1H-pyrrolo[2,3-b]pyridin-2-yl)-1H-indole-5-carboxamide
Experimental
Matched Name: … N-(2-hydroxy-1,1-dimethylethyl)-1-methyl-3-(1H-pyrrolo[2,3-b]pyridin-2-yl)-1H-indole-5-carboxamide …
Matched Iupac: … N-(1-hydroxy-2-methylpropan-2-yl)-1-methyl-3-{1H-pyrrolo[2,3-b]pyridin-2-yl}-1H-indole-5-carboxamide …
Matched Iupac: … N-(1-hydroxy-2-methylpropan-2-yl)-1-methyl-3-{1H-pyrrolo[2,3-b]pyridin-2-yl}-1H-indole-5-carboxamide …
ACE393
ACE393 is an injectable vaccine designed to combat the bacterium Campylobacter jejuni, one of the greatest causes of bacterial diarrhoeal infections in the developed world.
Investigational
SLV319
SLV319 belongs to a novel class of agents called CB1 antagonists, which work by blocking the cannabinoid type 1 (CB1) receptor. It is developed for the treatment of obesity and other metabolic disorders.
Investigational
CDP323
CDP323 is an antagonist of the vascular cell adhesion molecule 1 (VCAM-1) binding to alpha4-integrins (other adhesion molecules), a process thought to be implicated in the pathophysiology of Multiple Sclerosis (MS). It is considered a small-molecule prodrug. CDP323 was originally developed by the British biopharmaceutical company Celltech plc. (now UCB...
Investigational
IGN301
IGN301 is a cancer vaccine based on an anti-idiotypic antibody which provokes an immune response to Lewis Y. Lewis Y is a carbohydrate molecule expressed on the surface of tumor cells of epithelial origin (e.g. lung, intestinal, breast, prostate or ovarian cancers).
Investigational
ACR325
ACR325 is developed for the treatment of Parkinson’s disease and psychoses, including bipolar disorder, for which disease existing therapies have only limited effect and considerable adverse side effects. ACR325 is a dopaminergic stabiliser, which has demonstrated promising results in disease models for motor functions and psychoses.
Investigational
LY-3039478
LY3039478 has been used in trials studying the treatment and basic science of LYMPHOMA, Neoplasms, Solid Tumor, COLON CANCER, and BREAST CANCER, among others.
Investigational
Matched Iupac: … 4,4,4-trifluoro-N-[(1S)-1-{[(10S)-8-(2-hydroxyethyl)-9-oxo-6,8-diazatricyclo[9.4.0.0^{2,7}]pentadeca- …
GSK-356278
Gsk356278 has been used in trials studying the treatment and basic science of Anxiety Disorders, Huntington Disease, Depressive Disorder, Huntingtons Disease, and Depressive Disorder, Major, among others.
Investigational
Matched Iupac: … 3,4-b]pyridin-4-amine ... 5-{5-[(2,4-dimethyl-1,3-thiazol-5-yl)methyl]-1,3,4-oxadiazol-2-yl}-1-ethyl-N-(oxan-4-yl)-1H-pyrazolo[ …
Helium He-3
Helium He-3 is under investigation in clinical trial NCT00846014 (Asthma Exacerbation and Helium-3 MRI).
Investigational
Matched Synonyms: … Helium-3 ... Helium, He-3 …
Matched Name: … Helium He-3 …
Matched Description: … Helium He-3 is under investigation in clinical trial NCT00846014 (Asthma Exacerbation and Helium-3 MRI …
Matched Name: … Helium He-3 …
Matched Description: … Helium He-3 is under investigation in clinical trial NCT00846014 (Asthma Exacerbation and Helium-3 MRI …
SEP-363856
SEP-363856 is a novel psychotropic drug being investigated for the treatment of schizophrenia. Unlike other drugs used for this condition, SEP-363856 does not bind to the dopamine D2 receptors, but exerts actions on the trace amine–associated receptor 1 (TAAR1) and 5-hydroxytryptamine type 1A (5-HT1A). SEP-363856 was developed by Sunovion pharmaceuticals....
Investigational
Matched Description: … hydroxytryptamine type 1A (5-HT1A). ... the dopamine D2 receptors, but exerts actions on the trace amine–associated receptor 1 (TAAR1) and 5- …
CSL324
CSL324 is a fully human anti-G-CSFR antibody shown to have the ability to control G-CSF-mediated neutrophilia in cynomolgus macaques. It has potential applications in various inflammatory conditions such as cystic fibrosis, inflammatory bowel disease, rheumatoid arthritis, and vasculitis.
Investigational
ADXS-31164
Investigational
ARO-APOC3
ARO-APOC3 is an investigational RNAi therapeutic targeting apolipoprotein C-III (APOC3). It received an Orphan Drug designation by the FDA for the treatment of familial chylomicronemia syndrome.
Investigational
AAV-CNGB3
AAV-CNGB3 is an adenovirus associated viral vector serotype 8 containing the human CNGB3 gene.
Investigational
Maxy-G34
MAXY-G34 is a pegylated variant of human granulocyte-colony stimulating factor (G-CSF). This variant contains multiple non-naturally occurring lysines that have been introduced into alpha helixes of wild type human G-CSF as PEGylation sites, and from which multiple undesired, naturally occurring lysines have been removed as compared to wild type human...
Investigational
Matched Description: … MAXY-G34 is pegylated with 5 kd mPEG SPA (succinimidyl propionate) groups at 3 amino acid residues, including …
BMS-394136
BMS-394136 has been used in trials studying the diagnostic of Heart Diseases.
Investigational
Matched Iupac: … (2S)-1-[(7R)-7-(3,4-dichlorophenyl)-5-methyl-4H,7H-pyrazolo[1,5-a]pyrimidine-6-carbonyl]-2-(4-fluorophenyl …
PSI-352938
PSI-352938 has been used in trials studying the treatment of Hepatitis C and Hepatitis C, Chronic.
Investigational
Matched Iupac: … (2S,4aR,6R,7R,7aR)-6-(2-amino-6-ethoxy-9H-purin-9-yl)-7-fluoro-7-methyl-2-(propan-2-yloxy)-hexahydro- …
TMC-310911
TMC-310911 (also known as ASC-09) is a novel investigational protease inhibitor (PI) that is structurally similar to the currently available darunavir. It is being investigated for use in HIV-1 infections. TMC-310911 has shown marked activity against a variety of HIV-1 strains, including multi-PI-resistant strains, and may be less likely to...
Investigational
Matched Iupac: … (3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl N-[(2S,3R)-3-hydroxy-4-[N-(2-methylpropyl)2-[(1-cyclopentylpiperidin ... -4-yl)amino]-1,3-benzothiazole-6-sulfonamido]-1-phenylbutan-2-yl]carbamate …
RP-L301
RP-L301 is a lentiviral vector containing the human liver and erythroid pyruvate kinase gene.
Investigational
DNL343
DNL343 is under investigation in clinical trial NCT05842941 (HEALEY ALS Platform Trial - Regimen G DNL343).
Investigational
Displaying drugs 6576 - 6600 of 8133 in total