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Displaying drugs 651 - 675 of 709 in total

Zeluvalimab

Zeluvalimab is under investigation in clinical trial NCT04631601 (Safety and Efficacy of Therapies for Metastatic Castration-resistant Prostate Cancer (Mcrpc)).
Investigational
Matched Synonyms: … -chain, dimer ... glycine,305-cysteine), anti-(human programmed cell death 1) (human monoclonal 20c1.009 mab .gamma.1-chain …
Matched Description: … Zeluvalimab is under investigation in clinical trial NCT04631601 (Safety and Efficacy of Therapies for …

Licaminlimab

Licaminlimab is under investigation in clinical trial NCT05896670 (Safety and Efficacy of Licaminlimab Ophthalmic Suspension for the Treatment of Dry Eye Disease).
Investigational
Matched Synonyms: … sapiens TNF (tumor necrosis factor, TNFSF2, DIF, TNF-alpha)], humanized monoclonal antibody single chain ... ; IG scFv humanized single chain (V-KAPPA-VH) (1-254) [V-KAPPA (Homo sapiens IGKV1-5*03 (79.2%) -(IGHD …
Matched Description: … Licaminlimab is under investigation in clinical trial NCT05896670 (Safety and Efficacy of Licaminlimab …

Lonigutamab

Lonigutamab is under investigation in clinical trial NCT05683496 (Efficacy and Safety of Lonigutamab in Subjects With Thyroid Eye Disease (TED)).
Investigational
Matched Synonyms: … -chain, dimer ... anti-(human insulin-like growth factor i receptor) (human-mus musculus monoclonal hz208f2-4 .gamma.1-chain …
Matched Description: … Lonigutamab is under investigation in clinical trial NCT05683496 (Efficacy and Safety of Lonigutamab …

Aripiprazole

Aripiprazole is an atypical antipsychotic orally indicated for the treatment of schizophrenia, bipolar I, major depressive disorder, irritability associated with autism, and Tourette's. It is also indicated as an injection for agitation associated with schizophrenia or bipolar mania. Aripiprazole exerts its effects through agonism of dopaminergic and 5-HT1A receptors and...
Approved
Investigational
Matched Description: … [L45859] Aripiprazole exerts its effects through agonism of dopaminergic and 5-HT1A receptors and antagonism ... of alpha-adrenergic and 5-HT2A receptors. ... treatment of schizophrenia, bipolar I, major depressive disorder, irritability associated with autism, and …
Matched Categories: … Aripiprazole and prodrugs …
Matched Products: … Abilify Maintena 400 mg powder and solvent for prolonged-release suspension for injection ... ABILIFY MAINTENA POWDER AND SOLVENT FOR PROLONGED RELEASE SUSPENSION FOR INJECTION 400 MG …

Glycyrrhiza glabra

Glycyrrhiza glabra is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Approved
Experimental
Matched Synonyms: … Licorice Flavanoid Oil …
Matched Mixtures name: … Medi SM 24K Gold Hydrogel Peptide Mask Pack …

Ersodetug

Investigational
Matched Synonyms: … monoclonal RZ358 κ-chain, dimer ... gamma2 heavy chain Homo sapiens (1-444) [VH(Homo sapiens IGHV3-20*01 (98.0%) -(IGHD)-IGHJ6*01 (93.8%) ... Immunoglobulin G2, anti-(human insulin receptor) (human monoclonal RZ358 γ2-chain), disulfide with human …

Clervonafusp alfa

Investigational
Matched Synonyms: … -chain ... Immunoglobulin g1, (humanized monoclonal 3e10 .gamma.1-chain fab fragment) fusion protein with 67-952 …

Docetaxel

Docetaxel is a clinically well established anti-mitotic chemotherapy medication used for the treatment of different types of cancer, including breast, ovarian, and non-small cell lung cancer. Docetaxel is a complex diterpenoid molecule and a semisynthetic analogue of paclitaxel.[A259676,L46466] Docetaxel reversibly binds to microtubulin with high affinity in a 1:1 stoichiometric...
Approved
Investigational
Matched Description: … Docetaxel is a complex diterpenoid molecule and a semisynthetic analogue of [paclitaxel]. ... chemotherapy medication used for the treatment of different types of cancer, including breast, ovarian, and ... microtubulin with high affinity in a 1:1 stoichiometric ratio, allowing it to prevent cell division and …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … Oncotaxel Concentrate and solvent for solution for infusion 40 mg/ ml …

Miromavimab

Investigational
Matched Synonyms: … -chain, dimer ... evelyn-rockitniki-abelseth glycoprotein ectodomain epitope g-ii) (mus musculus monoclonal m777-16-3 .gamma.1-chain …

Lirentelimab

Lirentelimab is under investigation in clinical trial NCT04856891 (A Study of Lirentelimab (AK002) in Patients With Active Eosinophilic Duodenitis).
Investigational
Matched Synonyms: … -CHAIN, DIMER ... 8 (SIALOADHESIN FAMILY MEMBER 2, SIGLEC-8, SAF-2))HUMANIZED MOUSE MONOCLONAL ANTIBODY.GAMMA.1 HEAVY CHAIN ... G1, ANTI-(HUMAN SIALIC ACID-BINDINGE IG-LIKE LECTIN 8) (HUMAN-MUS MUSCULUS MONOCLONAL AK002 .GAMMA.1-CHAIN …
Matched Categories: … Amino Acids, Peptides, and Proteins …

Ascorbic acid

A six carbon compound related to glucose. It is found naturally in citrus fruits and many vegetables. Ascorbic acid is an essential nutrient in human diets, and necessary to maintain connective tissue and bone. Its biologically active form, vitamin C, functions as a reducing agent and coenzyme in several metabolic...
Approved
Nutraceutical
Matched Description: … Ascorbic acid is an essential nutrient in human diets, and necessary to maintain connective tissue and ... It is found naturally in citrus fruits and many vegetables. ... Its biologically active form, vitamin C, functions as a reducing agent and coenzyme in several metabolic …
Matched Mixtures name: … Kordel"s Bio-Liquid Women"s Multi With Fish Oil Vegicap ... Oil ... Melaleuca Oligo VFL MULTIVITAMIN & MINERAL …
Matched Categories: … Alimentary Tract and Metabolism ... Diet, Food, and Nutrition ... Vitamin C and analogues ... Genito Urinary System and Sex Hormones ... ascorbic acid (vit C) and calcium …
Matched Products: … Sodium Ascorbate and Ascorbic Acid Pwr ... Vit.c With N-M.bioflav.rose Hips and Rutin ... Timed Release and Esterified Vitamin C-1000 …

Dezamizumab

Dezamizumab is under investigation in clinical trial NCT03417830 (Biodistribution of 89Zirconium-labelled GSK2398852 Using PET Imaging).
Investigational
Matched Synonyms: … ), DISULFIDE WITH HUMAN-MUS MUSCULUS MONOCLONAL GSK2398852 LIGHT CHAIN, DIMER ... IMMUNOGLOBULIN G1, ANTI-(SERUM AMYLOID P PROTEIN) (HUMAN-MUS MUSCULUS MONOCLONAL GSK2398852 HEAVY CHAIN …
Matched Categories: … Amino Acids, Peptides, and Proteins …

Ulviprubart

Investigational
Matched Synonyms: … ), disulfide with human-Mus musculus monoclonal ABC008 κ-chain, dime ... gamma1 heavy chain humanized (1-449) [VH humanized (Homo sapiens IGHV1-8*01 (81.6%) -(IGHD) -IGHJ5*01 ... human killer cell lectin-like receptor subfamily G member 1) (human-Mus musculus monoclonal ABC008 γ1-chain …

KITE-222

Investigational
Matched Synonyms: … autologous chimeric antigen receptor (CAR) T-cell therapy engineered to express an antibody-derived single-chain …

Acimtamig

Acimtamig is a tetravalent bispecific chimeric anti-human CD30 x anti-human CD16A recombinant antibody construct.
Investigational
Matched Synonyms: … Immunoglobulin, anti-(human FcγRIIIa receptor) (human heavy chain V-D-J region) fusion protein with peptide ... linker (GGS)3 fusion protein with immunoglobulin anti-(human CD30 antigen) (human-Mus musculus single-chain …
Matched Categories: … Amino Acids, Peptides, and Proteins …

Obexelimab

Obexelimab is under investigation in clinical trial NCT02725515 (A Study of the Effect of XmAb®5871 in Patients With Systemic Lupus Erythematosus).
Investigational
Matched Synonyms: … with human-mus musculus monoclonal XMAB5871 light chain, dimer ... Immunoglobulin G1, anti-(human CD19 antigen) (human-mus musculus monoclonal XMAB5871 heavy chain), disulfide …

Maplirpacept

Maplirpacept is a recombinant fusion protein consisting of the CD47-binding domain of human signal regulatory protein alpha (SIRPa) linked to the IgG4 Fc region of human IgG.
Investigational
Matched Synonyms: … 118-Signal regulatory protein α (human) fusion protein with immunoglobulin G4 [128-proline] (human γ4-chain …

Retlirafusp alfa

Investigational
Matched Synonyms: … -chain, dimer ... 446-alanine), anti-(human programmed death-ligand 1) (human-mus musculus monoclonal SHR-1316 .gamma.4-chain …
Matched Categories: … Amino Acids, Peptides, and Proteins …

Ciprofloxacin

Ciprofloxacin is a second generation fluoroquinolone that has spawned many derivative antibiotics. It is formulated for oral, intravenous, intratympanic, ophthalmic, and otic administration for a number of bacterial infections.[L6469,L6472,L6475,L6478,L6481,L6484,L6487,L6490,L6493] The first ciprofloxacin containing product was FDA approved on 22 October 1987.
Approved
Investigational
Matched Description: … [A178870] It is formulated for oral, intravenous, intratympanic, ophthalmic, and otic administration …
Matched Mixtures name: … Ciprofloxacin and Dexamethasone ... Ciprofloxacin and Dexamethasone ... Ciprofloxacin and Dexamethasone …
Matched Categories: … ciprofloxacin and tinidazole ... ciprofloxacin and ornidazole ... ciprofloxacin and metronidazole ... Drug-Related Side Effects and Adverse Reactions ... Ophthalmological and Otological Preparations …
Matched Products: … Ciprofloxacin and Dextrose ... CILOXAN STERILE OPHTHALMIC AND OTIC SOLUTION 0.3% …

Sevelamer

Sevelamer is a phosphate binding drug used to prevent hyperphosphataemia in patients with chronic renal failure. It is marketed by Genzyme under the trade name Renagel.
Approved
Matched Categories: … Drugs for Treatment of Hyperkalemia and Hyperphosphatemia …
Matched Products: … Sevelamercarbonat Medice 800 mg Filmtabletten …

Sabatolimab

Sabatolimab is under investigation in clinical trial NCT03946670 (A Study of MBG453 in Combination With Hypomethylating Agents in Subjects With IPSS-R Intermediate, High or Very High Risk Myelodysplastic Syndrome (MDS).).
Investigational
Matched Synonyms: … -chain, dimer ... human hepatitis virus a cellular receptor 2) (human-mus musculus monoclonal clone nvs260714 .gamma.4-chain …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES …

Catridecacog

Coagulation Factor XIII A-Subunit (Recombinant), also known as catridecacog, is a recombinant form of the Factor XIII-A2 homodimer composed of two factor XIII (FXIII) A-subunits [FDA Label]. For people with congenital deficiency or mutation of Factor XIII, a rare bleeding disorder, exogenous replacement of this key coagulation factor is essential...
Approved
Matched Synonyms: … Blood Coagulation Factor XIII (Synthetic Human A-Chain Precursor) …
Matched Description: … and maintenance of hemostasis [A18581]. ... in increased mechanical strength and resistance to fibrinolysis of the fibrin clot. ... , including hydrophobic interaction and ion exchange chromatography [FDA Label]. …
Matched Categories: … Blood and Blood Forming Organs …

Ivonescimab

Ivonescimab is under investigation in clinical trial NCT05184712 (Phase 3 Clinical Study of AK112 for NSCLC Patients).
Investigational
Matched Synonyms: … ALANINE), ANTI-(HUMAN VASCULAR ENDOTHELIAL GROWTH FACTOR A) (HUMAN-MUS MUSCULUS MONOCLONAL AK112 .GAMMA.1-CHAIN …

Beludavimab

Beludavimab is under investigation in clinical trial NCT04746183 (AGILE (Early Phase Platform Trial for COVID-19)).
Investigational
Matched Synonyms: … SYNDROME CORONAVIRUS 2 SPIKE GLYCOPROTEIN RECEPTOR-BINDING DOMAIN) (HUMAN MONOCLONAL VIR-7832 .GAMMA.1-CHAIN …
Matched Categories: … Amino Acids, Peptides, and Proteins …

Nemvaleukin alfa

Investigational
Matched Synonyms: … -chain (human) ... human) fusion protein with peptide linker (GSGGGS) fusion protein with 1-165-interleukin 2 receptor α-chain ... interleukin 2 fragment (62-132), fused via peptidyl linker (133GSGGGS138) to human interleukin 2 receptor α-chain …
Displaying drugs 651 - 675 of 709 in total