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Displaying drugs 651 - 675 of 1085 in total
Thrombotic microangiopathies (TMA), including thrombotic thrombocytopenic purpura and atypical hemolytic uremic syndrome, are associated with injury and dysregulation of microvascular endothelium and platelets. Evidence increasingly points to a role for the complement system in TMA.[A241030, A241040] Mannan-associated lectin-binding serine protease-2 (MASP-2) is a major effector in the complement lectin pathway.[A241030,...
Investigational
Matched Synonyms: … IMMUNOGLOBULIN G4 (226-PROLINE), ANTI-(HUMAN MANNAN-BINDING LECTIN-ASSOCIATED SERINE PROTEASE 2) (HUMAN ... IMMUNOGLOBULIN G4-LAMBDA, ANTI-(HOMO SAPIENS MANNAN-BINDING LECTIN SERINE PROTEASE 2 (MANNOSE-BINDING ... PROTEIN-ASSOCIATED SERINE PROTEASE 2, EC=3.4.21.104) HUMAN MONOCLONAL ANTIBODY .GAMMA.4 HEAVY CHAIN …
Matched Description: … uremic syndrome, are associated with injury and dysregulation of microvascular endothelium and platelets ... Thrombotic microangiopathies (TMA), including thrombotic thrombocytopenic purpura and atypical hemolytic ... consideration as a treatment for hematopoietic stem cell transplant-associated TMA (HSCT-TMA/TA-TMA) and
Matched Categories: … Amino Acids, Peptides, and Proteins …
Experimental
Matched Synonyms: … N-(3-Propylcarbamoyloxirane-2-carbonyl)-isoleucyl-proline
Matched Name: … N-(3-Propylcarbamoyloxirane-2-Carbonyl)-Isoleucyl-Proline
Matched Categories: … Amino Acids, Peptides, and Proteins …
Experimental
Investigational
Matched Categories: … Enzymes and Coenzymes …
Matched Products: … Lysome Syrup …
Experimental
Matched Synonyms: … (3-(N-Hydroxy)carboxamido-2-benzylpropanoyl)alanine
Matched Categories: … Amino Acids, Peptides, and Proteins …
Approved
Experimental
Matched Synonyms: … Resorcinol acetate
Matched Iupac: … 3-hydroxyphenyl acetate
Investigational
Matched Synonyms: … Pam2CSK4 acetate
Matched Categories: … Amino Acids, Peptides, and Proteins …
Experimental
Matched Synonyms: … N-acetyl-L-alanine ... N-Acetyl-S-alanine ... N-acetyl-L-α-alanine
Matched Categories: … Amino Acids, Peptides, and Proteins …
Mecbotamab vedotin is an anti-Axl humanized monoclonal antibody conjugated to monomethyl auristatin E using a cleavable linker (CAB-Axl-ADC).
Investigational
Matched Synonyms: … IMMUNOGLOBULIN G1 (DE-450-LYSINE), ANTI-(HUMAN TYROSINE KINASE RECEPTOR AXL) (HUMAN-MUS MUSCULUS MONOCLONAL …
Experimental
Matched Name: … Lysine Nz-Carboxylic Acid …
Experimental
Matched Synonyms: … Glycine max seed sterol ... Glycine soja (soybean) sterols …
Experimental
Matched Name: … N-Carbamyl-D-Methionine
Investigational
Matched Synonyms: … -alanine ... Amidino beta-alanine
Illicit
Matched Synonyms: … dl-alpha-prodine
Experimental
Matched Name: … [2,4,6-Triisopropyl-Phenylsulfonyl-L-[3-Amidino-Phenylalanine]]-Piperazine-N'-Beta-Alanine
LTI-03 is a caveolin-1 Scaffolding Domain 7-Mer
Investigational
Matched Synonyms: … L-threonine, l-phenylalanyl-l-threonyl-l-threonyl-l-phenylalanyl-l-threonyl-l-valyl- …
HMI-102 is an investigational gene therapy designed to encode the phenylalanine-4-hydroxylase (PAH) gene, mutated in people with phenylketonuria.
Investigational
Matched Synonyms: … Recombinant adeno-associated viral vector serotype HSC expressing human phenylalanine hydroxylase …
Matched Description: … HMI-102 is an investigational gene therapy designed to encode the phenylalanine-4-hydroxylase (PAH) gene …
A naturally occurring glucocorticoid. It has been used in replacement therapy for adrenal insufficiency and as an anti-inflammatory agent. Cortisone itself is inactive. It is converted in the liver to the active metabolite hydrocortisone. (From Martindale, The Extra Pharmacopoeia, 30th ed, p726)
Experimental
Matched Description: … It has been used in replacement therapy for adrenal insufficiency and as an anti-inflammatory agent. …
Matched Categories: … Sex Hormones and Insulins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … CORTONE ACETATO
Experimental
Matched Synonyms: … Lauryl dimethyl glycine
Matched Iupac: … 2-(dodecyldimethylazaniumyl)acetate
Experimental
Matched Name: … Propyl acetate
Matched Iupac: … propyl acetate
[methyltelluro]acetate is a solid. This compound belongs to the organic oxoanionic compounds. These are organic compounds containing an oxoanion. This medication targets the protein monomeric sarcosine oxidase.
Experimental
Matched Name: … [Methyltelluro]Acetate
Matched Iupac: … 2-(methyltellanyl)acetate
Matched Description: … [methyltelluro]acetate is a solid. This compound belongs to the organic oxoanionic compounds. …
Telapristone acetate, an orally-available, selective progesterone receptor modulator, is in development to alleviate symptoms associated with both uterine fibroids and endometriosis.
Investigational
Matched Synonyms: … Telapristone acetate
Matched Name: … Telapristone acetate
Matched Iupac: … methoxyacetyl)-11a-methyl-7-oxo-1H,2H,3H,3aH,3bH,4H,5H,7H,8H,9H,10H,11H,11aH-cyclopenta[a]phenanthren-1-yl acetate
Matched Description: … to alleviate symptoms associated with both uterine fibroids and endometriosis. ... Telapristone acetate, an orally-available, selective progesterone receptor modulator, is in development …
Nomegestrol acetate, also known as NOMAC, is a progestin used in oral contraceptives, menopausal hormone therapy, and for the treatment of gynecological disorders.
Approved
Investigational
Matched Synonyms: … Nomegestrol acetate ... 17-alpha-Hydroxy-6-methyl-19-norpregna-4,6-diene-3,20-dione acetate
Matched Name: … Nomegestrol acetate
Matched Iupac: … acetyl-5,11a-dimethyl-7-oxo-1H,2H,3H,3aH,3bH,7H,8H,9H,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-1-yl acetate
Matched Description: … therapy, and for the treatment of gynecological disorders. ... Nomegestrol acetate, also known as NOMAC, is a progestin used in oral contraceptives, menopausal hormone …
Matched Categories: … Combination Contraceptives (with Estrogen and derivatives) …
Segesterone acetate is a steroidal progestin or synthetic progesterone and a 19-norprogesterone derivative with no CH3 group radical in position 6 . In animal studies, segesterone acetate was shown to be one of the most potent progestins . It mediates progestational activity 100 times higher than that of progesterone ....
Approved
Experimental
Investigational
Matched Synonyms: … Segesterone acetate ... 17-Hydroxy-16-methylene-19-norpregn-4-ene-3,20-dione acetate
Matched Name: … Segesterone acetate
Matched Iupac: … methylidene-7-oxo-1H,2H,3H,3aH,3bH,4H,5H,7H,8H,9H,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-1-yl acetate
Matched Description: … Segesterone acetate is a steroidal progestin or synthetic progesterone and a 19-norprogesterone derivative ... Segesterone acetate binds selectively to progesterone receptors and not androgen receptors [A37083]. ... On August 10, 2018, Annovera™ containing segesterone acetate and [ethinyl estradiol] was granted approval …
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists …
A naturally occurring amino acid in both eukaryotic and prokaryotic organisms. It is found in tRNAs and in the catalytic site of some enzymes. The genes for glutathione peroxidase and formate dehydrogenase contain the TGA codon, which codes for this amino acid. [PubChem]
Experimental
Matched Synonyms: … 3-selenyl-L-alanine
Matched Description: … A naturally occurring amino acid in both eukaryotic and prokaryotic organisms. ... It is found in tRNAs and in the catalytic site of some enzymes. ... The genes for glutathione peroxidase and formate dehydrogenase contain the TGA codon, which codes for …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Experimental
Matched Name: … [Methylseleno]Acetate
Matched Iupac: … 2-(methylselanyl)acetate
Displaying drugs 651 - 675 of 1085 in total