Displaying drugs 6851 - 6875 of 12169 in total
Mefuparib
Investigational
Matched Synonyms: … 5-fluoro-2-(4-((methylamino)methyl)phenyl)-7-benzofurancarboxamide …
Matched Iupac: … 5-fluoro-2-{4-[(methylamino)methyl]phenyl}-1-benzofuran-7-carboxamide …
Matched Iupac: … 5-fluoro-2-{4-[(methylamino)methyl]phenyl}-1-benzofuran-7-carboxamide …
3-Chlorophenol
Experimental
CP-122721
CP-122721, neurokinin 1 (NK1) antagonist is developed by Pfizer to treat depression, emesis, and inflammatory diseases including asthma and irritable bowel syndrome.
Investigational
Matched Iupac: … (2S,3S)-N-{[2-methoxy-5-(trifluoromethoxy)phenyl]methyl}-2-phenylpiperidin-3-amine …
Matched Description: … CP-122721, neurokinin 1 (NK1) antagonist is developed by Pfizer to treat depression, emesis, and inflammatory …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Description: … CP-122721, neurokinin 1 (NK1) antagonist is developed by Pfizer to treat depression, emesis, and inflammatory …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
PBGM01
PBGM01 is a non-replicating recombinant adeno-associated virus serotype hu68 vector, which contains human GLB1 transgene encoding the galactosidase beta 1 enzyme.
Investigational
Matched Description: … adeno-associated virus serotype hu68 vector, which contains human GLB1 transgene encoding the galactosidase beta 1 …
Semzuvolimab
Semzuvolimab is under investigation in clinical trial NCT03149211 (To Investigate the Efficacy and Safety of UB-421 Monotherapy in HIV-1 Infected Adults).
Investigational
Matched Description: … in clinical trial NCT03149211 (To Investigate the Efficacy and Safety of UB-421 Monotherapy in HIV-1 …
Selitrectinib
Selitrectinib is under investigation in clinical trial NCT03215511 (Phase 1/2 Study of LOXO-195 in Patients With Previously Treated NTRK Fusion Cancers).
Investigational
Matched Iupac: … )-9-fluoro-15-methyl-2,11,16,20,21,24-hexaazapentacyclo[16.5.2.0^{2,6}.0^{7,12}.0^{21,25}]pentacosa-1( …
Matched Description: … Selitrectinib is under investigation in clinical trial NCT03215511 (Phase 1/2 Study of LOXO-195 in Patients …
Matched Description: … Selitrectinib is under investigation in clinical trial NCT03215511 (Phase 1/2 Study of LOXO-195 in Patients …
HIV Integrase Inhibitor
HIV Integrase Inhibitor is under investigation in clinical trial NCT00397566 (A Multiple Ascending Dose Study of BMS-707035 in HIV-1 Infected Subjects).
Investigational
Matched Iupac: … 2-(1,1-dioxo-1lambda6,2-thiazinan-2-yl)-N-[(4-fluorophenyl)methyl]-5-hydroxy-1-methyl-6-oxo-1,6-dihydropyrimidine ... -4-carboxamide …
Matched Description: … under investigation in clinical trial NCT00397566 (A Multiple Ascending Dose Study of BMS-707035 in HIV-1 …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Description: … under investigation in clinical trial NCT00397566 (A Multiple Ascending Dose Study of BMS-707035 in HIV-1 …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Gotistobart
Gotistobart is under investigation in clinical trial NCT05671510 (ONC-392 Versus Docetaxel in Metastatic NSCLC That Progressed on PD-1/PD-L1 Inhibitors).
Investigational
Matched Description: … investigation in clinical trial NCT05671510 (ONC-392 Versus Docetaxel in Metastatic NSCLC That Progressed on PD-1/ …
Modipafant
Modipafant is under investigation in clinical trial NCT02569827 (Celgosivir or Modipafant as Treatment for Adult Participants With Uncomplicated Dengue Fever in Singapore).
Investigational
Matched Iupac: … ethyl (4R)-4-(2-chlorophenyl)-6-methyl-2-(4-{2-methyl-1H-imidazo[4,5-c]pyridin-1-yl}phenyl)-5-[(pyridin …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
4-(2,5-Dichloro-Thiophen-3-Yl)-Pyrimidin-2-Ylamine
Experimental
Matched Name: … 4-(2,5-Dichloro-Thiophen-3-Yl)-Pyrimidin-2-Ylamine …
Matched Iupac: … 4-(2,5-dichlorothiophen-3-yl)pyrimidin-2-amine …
Matched Iupac: … 4-(2,5-dichlorothiophen-3-yl)pyrimidin-2-amine …
Barbexaclone
Barbexaclone, a salt compound of propylhexedrine and phenobarbital, is a potent antiepileptic. By weight, barbexaclone is 40% propylhexedrine and 60% phenobarbital. While barbexaclone has sedative properties, propylhexedrine has psychostimulant properties intended to offset these sedative effects. Pharmacokinetic studies have demonstrated that the pharmacokinetics of phenobarbital given as barbexaclone are not...
Experimental
Matched Iupac: … 5-ethyl-5-phenyl-1,3-diazinane-2,4,6-trione; [(2S)-1-cyclohexylpropan-2-yl](methyl)amine …
Matched Description: … By weight, barbexaclone is 40% propylhexedrine and 60% phenobarbital. …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Description: … By weight, barbexaclone is 40% propylhexedrine and 60% phenobarbital. …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
7,8-dihydroxy-4-phenyl-2H-chromen-2-one
Experimental
Matched Name: … 7,8-dihydroxy-4-phenyl-2H-chromen-2-one …
Matched Iupac: … 7,8-dihydroxy-4-phenyl-2H-chromen-2-one …
Matched Iupac: … 7,8-dihydroxy-4-phenyl-2H-chromen-2-one …
FG-9041
Experimental
Pittsburgh Compound B
Pittsburgh Compound B is under investigation in clinical trial NCT01723553 (Amyloid-related Imaging Abnormalities (Microbleeds) in Atypical AD).
Investigational
Matched Synonyms: … 2-(4'-(methylamino)phenyl)-6-hydroxybenzothiazole ... (N-methyl-(11C))2-(4'-methylaminophenyl)-6-hydroxybenzothiazole …
Matched Iupac: … 2-{4-[(11C)methylamino]phenyl}-1,3-benzothiazol-6-ol …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Iupac: … 2-{4-[(11C)methylamino]phenyl}-1,3-benzothiazol-6-ol …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Tarenflurbil
Tarenflurbil is an investigational drug that was studied in patients with mild Alzheimer's disease. It is a selective amyloid lowering agent (SALA) that reduces levels of the toxic peptide amyloid beta 42 (Aβ42) in cultured human cells and in animal models. Aβ42 is the primary initiator of neurotoxicity and amyloid...
Investigational
Matched Synonyms: … (2R)-2-(2-fluorobiphenyl-4-yl)propanoic acid ... (−)-(2R)-2-(2-fluorobiphenyl-4-yl)propanoic acid ... (R)-2-fluoro-α-methyl(1,1'-biphenyl)-4-acetic acid …
Matched Iupac: … (2R)-2-{2-fluoro-[1,1'-biphenyl]-4-yl}propanoic acid …
Matched Iupac: … (2R)-2-{2-fluoro-[1,1'-biphenyl]-4-yl}propanoic acid …
Curcumin sulfate
Experimental
Matched Iupac: … {4-[(1E,6E)-7-(4-hydroxy-3-methoxyphenyl)-3,5-dioxohepta-1,6-dien-1-yl]-2-methoxyphenyl}oxidanesulfonic …
CD564
Experimental
LY-517717
LY517717 is an investigational oral direct inhibitor of activated Factor Xa. It is believed to be Lilly's PMD-3112 (licensed from Amgen).
Investigational
Matched Iupac: … N-[(1R)-2-[4-(1-methylpiperidin-4-yl)piperazin-1-yl]-2-oxo-1-phenylethyl]-1H-indole-6-carboxamide …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
CX516
Investigational
Matched Iupac: … 6-(piperidine-1-carbonyl)quinoxaline …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
GW-590735
Investigational
Matched Iupac: … 2-methyl-2-{4-[({4-methyl-2-[4-(trifluoromethyl)phenyl]-1,3-thiazol-5-yl}formamido)methyl]phenoxy}propanoic …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
CP-547632
CP-547632 has been used in trials studying the treatment of Ovarian Cancer, Lung Neoplasms, Ovarian Neoplasms, Peritoneal Neoplasms, and Fallopian Tube Cancer, among others.
Investigational
Matched Iupac: … 3-[(4-bromo-2,6-difluorophenyl)methoxy]-5-({[4-(pyrrolidin-1-yl)butyl]carbamoyl}amino)-1,2-thiazole-4 …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
FT516
FT516 is an investigational and engineered off-the-shelf natural killer (NK) cell therapy originating from induced pluripotent stem cells (iPSC). This compound expresses a high-affinity 158V, CD16 (hnCD16) Fc receptor that has an enhanced binding ability to tumor-targeting antibodies, and is resistant to downregulation. FT516 is currently being tested against acute...
Investigational
VAC-52150
Investigational
TP-271
TP-271 is under investigation in clinical trial NCT02724085 (A Phase 1 Study to Assess the Safety, Tolerability and PK of IV TP-271).
Investigational
Matched Iupac: … 5,5a,6,6a,7,10,10a,12-octahydrotetracen-2-yl]-1-methylpyrrolidine-2-carboxamide ... (2S)-N-[(5aR,6aS,7S,10aS)-9-carbamoyl-7-(dimethylamino)-4-fluoro-1,8,10a,11-tetrahydroxy-10,12-dioxo- …
Matched Description: … TP-271 is under investigation in clinical trial NCT02724085 (A Phase 1 Study to Assess the Safety, Tolerability …
Matched Description: … TP-271 is under investigation in clinical trial NCT02724085 (A Phase 1 Study to Assess the Safety, Tolerability …
Snubh-nm-333 F-18
Snubh-nm-333 F-18 is under investigation in clinical trial NCT02149017 (Phase 1 and Phase 2 Clinical Trials of SNUBH-NM-333(18F)).
Investigational
Matched Iupac: … 4-[6-(¹⁸F)fluoro-1,3-benzothiazol-2-yl]-N-methylaniline …
Matched Description: … Snubh-nm-333 F-18 is under investigation in clinical trial NCT02149017 (Phase 1 and Phase 2 Clinical …
Matched Description: … Snubh-nm-333 F-18 is under investigation in clinical trial NCT02149017 (Phase 1 and Phase 2 Clinical …
Displaying drugs 6851 - 6875 of 12169 in total