Displaying drugs 676 - 700 of 1155 in total
Plasminogen
Plasminogen is a pro-enzyme (i.e. a zymogen) which is cleaved to form plasmin - also known as fibrinolysin - as part of the fibrinolytic pathway that breaks down fibrin blood clots. This pathway is activated when a clot is no longer needed or to prevent a clot from extending beyond...
Approved
Matched Synonyms: … Human plasminogen ... plasminogen, human-tvmh …
Matched Description: … [L34615] It is the first and only FDA-approved treatment for this condition, which causes wood-like lesions ... [L34635] In June 2021, the FDA approved a plasma-derived plasminogen (Ryplazim, human plasminogen-tvmh …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Enzymes and Coenzymes ... Proteins ... Blood Proteins ... Protein Precursors …
Matched Description: … [L34615] It is the first and only FDA-approved treatment for this condition, which causes wood-like lesions ... [L34635] In June 2021, the FDA approved a plasma-derived plasminogen (Ryplazim, human plasminogen-tvmh …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Enzymes and Coenzymes ... Proteins ... Blood Proteins ... Protein Precursors …
Neisseria meningitidis group w-135 capsular oligosaccharide diphtheria crm197 protein conjugate antigen
Neisseria meningitidis group w-135 capsular oligosaccharide diphtheria crm197 protein conjugate antigen is a vaccine.
Approved
Matched Name: … Neisseria meningitidis group w-135 capsular oligosaccharide diphtheria crm197 protein conjugate antigen …
Matched Description: … Neisseria meningitidis group w-135 capsular oligosaccharide diphtheria crm197 protein conjugate antigen …
Matched Description: … Neisseria meningitidis group w-135 capsular oligosaccharide diphtheria crm197 protein conjugate antigen …
C-peptide
C-peptide is under investigation in clinical trial NCT00278980 (Effect of C-peptide on Diabetic Peripheral Neuropathy).
Investigational
Matched Synonyms: … Human c-peptide ... Human proinsulin c-peptide ... Proinsulin c-peptide (human) …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Netakimab
Netakimab is under investigation in clinical trial NCT03447704 (International Multicenter Comparative Randomized Placebo-controlled Clinical Study of Efficacy and Safety of BCD-085 in Patients With Ankylosing Spondylitis).
Investigational
Matched Synonyms: … Immunoglobulin g1, anti-(human interleukin 17) (human-lama glama monoclonal heavy chain), disulfide with ... human monoclonal light chain, dimer …
Matched Description: … NCT03447704 (International Multicenter Comparative Randomized Placebo-controlled Clinical Study of Efficacy and …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Proteins ... Blood Proteins …
Matched Description: … NCT03447704 (International Multicenter Comparative Randomized Placebo-controlled Clinical Study of Efficacy and …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Proteins ... Blood Proteins …
Human interferon omega-1
Human interferon omega 1 (IFN-omega 1 = IFN-alpha II1) is a recently discovered protein structurally related to IFN-alpha and -beta. It occurs naturally in the human body and is currently being manufactured by Intarcia through genetic engineering. There are multiple routes for administration of omega interferon: injection, an implantable subcutaneous...
Investigational
Matched Synonyms: … Human interferon omega 1 …
Matched Name: … Human interferon omega-1 …
Matched Description: … Human interferon omega 1 (IFN-omega 1 = IFN-alpha II1) is a recently discovered protein structurally ... It occurs naturally in the human body and is currently being manufactured by Intarcia through genetic ... related to IFN-alpha and -beta. …
Matched Name: … Human interferon omega-1 …
Matched Description: … Human interferon omega 1 (IFN-omega 1 = IFN-alpha II1) is a recently discovered protein structurally ... It occurs naturally in the human body and is currently being manufactured by Intarcia through genetic ... related to IFN-alpha and -beta. …
cryopreserved human liver cells
Vesta Therapeutics is a privately held company developing cell therapeutics for liver repair and regeneration. The Company's technology is centered on the isolation, expansion, and cryopreservation of liver cells (human hepatocytes) obtained from organ donor livers that are not suitable for whole organ transplantation.
Investigational
Matched Name: … cryopreserved human liver cells …
Matched Description: … Vesta Therapeutics is a privately held company developing cell therapeutics for liver repair and regeneration ... The Company's technology is centered on the isolation, expansion, and cryopreservation of liver cells ... (human hepatocytes) obtained from organ donor livers that are not suitable for whole organ transplantation …
Matched Description: … Vesta Therapeutics is a privately held company developing cell therapeutics for liver repair and regeneration ... The Company's technology is centered on the isolation, expansion, and cryopreservation of liver cells ... (human hepatocytes) obtained from organ donor livers that are not suitable for whole organ transplantation …
Coagulation factor VII human
Coagulation factor VII is human serine protease type enzyme that is involved in the extrinsic coagulation cascade which results in blood clotting.
Approved
Investigational
Matched Synonyms: … Factor VII human ... Coagulation factor VII (human) ... Human coagulation factor VII …
Matched Name: … Coagulation factor VII human …
Matched Description: … Coagulation factor VII is human serine protease type enzyme that is involved in the extrinsic coagulation …
Matched Mixtures name: … OCTAPLEX POWDER AND SOLVENT FOR SOLUTION FOR INJECTION ... OCTAPLEX POWDER AND SOLVENT FOR SOLUTION FOR INJECTION 500 IU …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Blood and Blood Forming Organs ... Enzymes and Coenzymes ... coagulation factor IX, II, VII and X in combination ... Proteins …
Matched Name: … Coagulation factor VII human …
Matched Description: … Coagulation factor VII is human serine protease type enzyme that is involved in the extrinsic coagulation …
Matched Mixtures name: … OCTAPLEX POWDER AND SOLVENT FOR SOLUTION FOR INJECTION ... OCTAPLEX POWDER AND SOLVENT FOR SOLUTION FOR INJECTION 500 IU …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Blood and Blood Forming Organs ... Enzymes and Coenzymes ... coagulation factor IX, II, VII and X in combination ... Proteins …
Palucorcel
Palucorcel is an investigational stem cell therapy consisting of human umbilical tissue-derived cells. Developed by Janssen Biotech, it is being investigated for the treatment of various conditions such as amyotrophic lateral sclerosis (ALS) and macular degeneration.
Investigational
Matched Synonyms: … Human umbilical tissue-derived cells ... HUMAN UMBILICAL TISSUE-DERIVED CELLS (ALLOGENIC) …
Matched Description: … being investigated for the treatment of various conditions such as amyotrophic lateral sclerosis (ALS) and ... Palucorcel is an investigational stem cell therapy consisting of human umbilical tissue-derived cells …
Matched Description: … being investigated for the treatment of various conditions such as amyotrophic lateral sclerosis (ALS) and ... Palucorcel is an investigational stem cell therapy consisting of human umbilical tissue-derived cells …
Urabrelimab
Investigational
Matched Synonyms: … Immunoglobulin igg4, anti-(human cd47) (human monoclonal srf231 .gamma.4-chain), disulfide with human …
Heterologous human adult liver derived progenitor cells
Investigational
Matched Synonyms: … Human heterologous liver cells ... Heterologous human adult liver derived progenitor cells …
Matched Name: … Heterologous human adult liver derived progenitor cells …
Matched Name: … Heterologous human adult liver derived progenitor cells …
Recombinant Alpha-1-antitrypsin
Investigational
Matched Synonyms: … Recombinant human alpha 1-antitrypsin ... Recombinant human alpha 1-antitrypsin (raat) …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Proteins ... Protease Inhibitors ... Serine Protease Inhibitors ... Proteinase Inhibitory Proteins, Secretory …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Proteins ... Protease Inhibitors ... Serine Protease Inhibitors ... Proteinase Inhibitory Proteins, Secretory …
Burfiralimab
Burfiralimab is under investigation in clinical trial NCT06306339 (A Study to Assess the Efficacy and Safety of Burfiralimab (Hzvsf-v13) and DMRD (Disease-modifying Antirheumatic Drug)).
Investigational
Matched Synonyms: … IMMUNOGLOBULIN G4, ANTI-(HUMAN VIMENTIN) (HUMAN-MUS MUSCULUS .GAMMA.4-CHAIN), DISULFIDE WITH HUMAN-MUS …
Matched Description: … Burfiralimab is under investigation in clinical trial NCT06306339 (A Study to Assess the Efficacy and ... Safety of Burfiralimab (Hzvsf-v13) and DMRD (Disease-modifying Antirheumatic Drug)). …
Matched Description: … Burfiralimab is under investigation in clinical trial NCT06306339 (A Study to Assess the Efficacy and ... Safety of Burfiralimab (Hzvsf-v13) and DMRD (Disease-modifying Antirheumatic Drug)). …
Vilamakitug
Vilamakitug is under investigation in clinical trial NCT05201352 (Evaluation of Efficacy of Trifluridine/tipiracil Plus an Anti-il-1α True Human Antibody Versus Trifluridine/tipiracil Plus Placebo in Metastatic Colorectal Cancer Patients After Failure of Oxaliplatin, Irinotecan, Fluoropyrimidine).
Investigational
Matched Synonyms: … (human monoclonal xb2001 .gamma.4-chain), disulfide with human monoclonal xb2001 .kappa. ... Immunoglobulin g4, anti-(human interleukin 1.alpha.) …
Matched Description: … clinical trial NCT05201352 (Evaluation of Efficacy of Trifluridine/tipiracil Plus an Anti-il-1α True Human …
Matched Description: … clinical trial NCT05201352 (Evaluation of Efficacy of Trifluridine/tipiracil Plus an Anti-il-1α True Human …
Human Lactoferrin Peptide hLF1-11
Human Lactoferrin Peptide hLF1-11 is under investigation in clinical trial NCT00509834 (A Study on the Tolerability and Early Efficacy of Hlf1-11 in Patients With Proven Candidaemia).
Investigational
Matched Synonyms: … Human lactoferrin 1-11 ... N-terminal peptide of human lactoferrin 1-11 …
Matched Name: … Human Lactoferrin Peptide hLF1-11 …
Matched Description: … Tolerability and Early Efficacy of Hlf1-11 in Patients With Proven Candidaemia). ... Human Lactoferrin Peptide hLF1-11 is under investigation in clinical trial NCT00509834 (A Study on the …
Matched Name: … Human Lactoferrin Peptide hLF1-11 …
Matched Description: … Tolerability and Early Efficacy of Hlf1-11 in Patients With Proven Candidaemia). ... Human Lactoferrin Peptide hLF1-11 is under investigation in clinical trial NCT00509834 (A Study on the …
Natalizumab
Natalizumab is a recombinant humanized IgG4κ monoclonal antibody that binds to α4-integrin. While natalizumab was originally approved by the FDA to treat multiple sclerosis in 2004, it was withdrawn from the market following multiple reports of fatal progressive multifocal leukoencephalopathy (PML). In 2006, the FDA reintroduced the drug to the...
Approved
Investigational
Matched Synonyms: … IMMUNOGLOBULIN G4 (HUMAN-MOUSE MONOCLONAL AN100226 4-CHAIN ANTI-HUMAN INTEGRIN 4), DISULFIDE WITH HUMAN-MOUSE ... IMMUNOGLOBULIN G4 (HUMAN-MOUSE MONOCLONAL AN100226 4-CHAIN ANTI-HUMAN INTEGRIN 4), DISULPHIDE WITH HUMAN-MOUSE …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Proteins ... Blood Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Proteins ... Blood Proteins …
Human vaccinia virus immune globulin
Human vaccinia immune globulin (VIG) is a sterile solution containing the purified gamma globulin (IgG) fraction of plasma taken from healthy donors previously vaccinated with live vaccinia virus vaccine who possess high titers of anti-vaccinia virus antibody [FDA Label, A33814]. The IgG fraction is purified by the anion-exchange column chromatography...
Approved
Matched Synonyms: … Human vaccinia immune globulin ... Vaccinia Immune Globulin (Human) Intravenous ... Vaccinia immune globulin intravenous (human) …
Matched Name: … Human vaccinia virus immune globulin …
Matched Description: … Nevertheless, VIG by virtue of the way it is produced is a poorly characterized and highly variable human ... The IgG fraction is purified by the anion-exchange column chromatography method and the solution is solvent ... is only available in very limited quantities - all factors that may intervene with its availability and …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Human Immunoglobulin G ... Proteins ... Blood Proteins …
Matched Name: … Human vaccinia virus immune globulin …
Matched Description: … Nevertheless, VIG by virtue of the way it is produced is a poorly characterized and highly variable human ... The IgG fraction is purified by the anion-exchange column chromatography method and the solution is solvent ... is only available in very limited quantities - all factors that may intervene with its availability and …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Human Immunoglobulin G ... Proteins ... Blood Proteins …
Sotatercept
Sotatercept is an activin signalling inhibitor. It is a homodimeric recombinant fusion protein consisting of the extracellular domain of the human activin receptor type IIA (ActRIIA) linked to the human IgG1 Fc domain. On March 26, 2024, sotatercept was approved by the FDA for the treatment of pulmonary arterial hypertension...
Approved
Investigational
Matched Synonyms: … ACTIVIN RECEPTOR TYPE IIA (SYNTHETIC HUMAN EXTRACELLULAR DOMAIN-CONTAINING FRAGMENT) FUSION PROTEIN WITH ... (HUMAN ACTIVIN RECEPTOR TYPE-2A PRECURSOR-(21-135)-PEPTIDYL)-THREONYLTRIGLYCYL-(HUMAN IMMUNOGLOBULIN ... (HUMAN ACTIVIN RECEPTOR TYPE-2A PRECURSOR-(21-135)-PEPTIDYL)-THREONYLTRIGLYCYL-(HUMAN IMMUNOGLOBULIN …
Matched Description: … [L50361] Sotatercept works to resolve the imbalance in activin–growth differentiation factor and BMP ... It is a homodimeric recombinant fusion protein consisting of the extracellular domain of the human activin ... receptor type IIA (ActRIIA) linked to the human IgG1 Fc domain. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Proteins ... Blood Proteins ... Recombinant Proteins ... Recombinant Fusion Proteins …
Matched Description: … [L50361] Sotatercept works to resolve the imbalance in activin–growth differentiation factor and BMP ... It is a homodimeric recombinant fusion protein consisting of the extracellular domain of the human activin ... receptor type IIA (ActRIIA) linked to the human IgG1 Fc domain. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Proteins ... Blood Proteins ... Recombinant Proteins ... Recombinant Fusion Proteins …
Protego-PD
Protego-PD is a post-delivery placental extract.
Investigational
Matched Name: … Protego-PD …
Matched Description: … Protego-PD is a post-delivery placental extract. …
Matched Description: … Protego-PD is a post-delivery placental extract. …
Bertilimumab
Bertilimumab is a fully human anti-eotaxin monoclonal antibody with potential in the treatment of allergic disorders, has moved into pre-clinical development. It is developed by MedImmune for the treatment of Allergic Rhinitis.
Investigational
Matched Synonyms: … IMMUNOGLOBULIN G4, ANTI-(HUMAN EOTAXIN 1) (HUMAN MONOCLONAL CAT-213 .GAMMA.4-CHAIN), DISULFIDE WITH HUMAN …
Matched Description: … Bertilimumab is a fully human anti-eotaxin monoclonal antibody with potential in the treatment of allergic …
Matched Description: … Bertilimumab is a fully human anti-eotaxin monoclonal antibody with potential in the treatment of allergic …
Remestemcel-L
Remestemcel-L is a third-party, off-the-shelf suspension of ex-vivo cultured adult human mesenchymal stem cells intended for intravenous infusion. The mesenchymal stem cells are derived from the bone marrow of unrelated and human leukocyte antigen (HLA)–unmatched healthy adult donors and have the ability to differentiate into different tissue cells. It was...
Approved
Investigational
Matched Synonyms: … Adult human mesenchymal stem cells ... Allogeneic human mesenchymal stem cell …
Matched Description: … The mesenchymal stem cells are derived from the bone marrow of unrelated and human leukocyte antigen ... Human mesenchymal stem cells (hMSCs) serve to down-regulate inflammatory responses and produce anti-inflammatory ... (HLA)–unmatched healthy adult donors and have the ability to differentiate into different tissue cells …
Matched Description: … The mesenchymal stem cells are derived from the bone marrow of unrelated and human leukocyte antigen ... Human mesenchymal stem cells (hMSCs) serve to down-regulate inflammatory responses and produce anti-inflammatory ... (HLA)–unmatched healthy adult donors and have the ability to differentiate into different tissue cells …
Dezamizumab
Dezamizumab is under investigation in clinical trial NCT03417830 (Biodistribution of 89Zirconium-labelled GSK2398852 Using PET Imaging).
Investigational
Matched Synonyms: … IMMUNOGLOBULIN G1, ANTI-(SERUM AMYLOID P PROTEIN) (HUMAN-MUS MUSCULUS MONOCLONAL GSK2398852 HEAVY CHAIN ... recombinant monoclonal antibody to human serum amyloid P component ... ), DISULFIDE WITH HUMAN-MUS MUSCULUS MONOCLONAL GSK2398852 LIGHT CHAIN, DIMER …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Proteins ... Blood Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Proteins ... Blood Proteins …
Recombinant human plasma gelsolin
Plasma gelsolin (pGSN) is a protein found in the blood of healthy individuals which scavenges compounds left over from damaged tissues.
Investigational
Matched Synonyms: … Recombinant human gelsolin …
Matched Name: … Recombinant human plasma gelsolin …
Matched Description: … Plasma gelsolin (pGSN) is a protein found in the blood of healthy individuals which scavenges compounds …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intracellular Signaling Peptides and Proteins ... Proteins ... Carrier Proteins ... Cytoskeletal Proteins …
Matched Name: … Recombinant human plasma gelsolin …
Matched Description: … Plasma gelsolin (pGSN) is a protein found in the blood of healthy individuals which scavenges compounds …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intracellular Signaling Peptides and Proteins ... Proteins ... Carrier Proteins ... Cytoskeletal Proteins …
Ginisortamab
Ginisortamab is under investigation in clinical trial NCT04393298 (A Study to Assess the Safety, Pharmacokinetics and Anti Tumor Activity of UCB6114 Administered Intravenously to Participants With Advanced Solid Tumors).
Investigational
Matched Synonyms: … Immunoglobulin g4 (232-proline), anti-(human gremlin 1) (human monoclonal ucb6114 .gamma.4-chain), disulfide ... with human monoclonal ucb6114 .kappa. …
Matched Description: … is under investigation in clinical trial NCT04393298 (A Study to Assess the Safety, Pharmacokinetics and …
Matched Description: … is under investigation in clinical trial NCT04393298 (A Study to Assess the Safety, Pharmacokinetics and …
Endothelin-1
Endothelin 1 is under investigation in clinical trial NCT00745693 (The Effects of Diesel Exhaust Inhalation on Vascular Function - the Role of Endothelin).
Investigational
Matched Synonyms: … Human endothelin ... Endothelin 1 (human) …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins ... Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins ... Proteins …
Coagulation factor X human
Coagulation Factor X (Human), is a plasma-derived human blood coagulation factor is used by adults and children (aged 12 years and above) with hereditary Factor X deficiency. However its use is limited in the perioperative setting for the management of bleeding in major surgery in patients with moderate and severe...
Approved
Investigational
Matched Synonyms: … Coagulation factor X (human) ... Human coagulation factor X …
Matched Name: … Coagulation factor X human …
Matched Description: … Coagulation Factor X (Human), is a plasma-derived human blood coagulation factor is used by adults and ... children (aged 12 years and above) with hereditary Factor X deficiency. ... the perioperative setting for the management of bleeding in major surgery in patients with moderate and …
Matched Mixtures name: … OCTAPLEX POWDER AND SOLVENT FOR SOLUTION FOR INJECTION ... OCTAPLEX POWDER AND SOLVENT FOR SOLUTION FOR INJECTION 500 IU …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Blood and Blood Forming Organs ... Enzymes and Coenzymes ... Proteins ... Blood Proteins …
Matched Name: … Coagulation factor X human …
Matched Description: … Coagulation Factor X (Human), is a plasma-derived human blood coagulation factor is used by adults and ... children (aged 12 years and above) with hereditary Factor X deficiency. ... the perioperative setting for the management of bleeding in major surgery in patients with moderate and …
Matched Mixtures name: … OCTAPLEX POWDER AND SOLVENT FOR SOLUTION FOR INJECTION ... OCTAPLEX POWDER AND SOLVENT FOR SOLUTION FOR INJECTION 500 IU …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Blood and Blood Forming Organs ... Enzymes and Coenzymes ... Proteins ... Blood Proteins …
Displaying drugs 676 - 700 of 1155 in total