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Displaying drugs 676 - 700 of 954 in total
Bazlitoran is under investigation in clinical trial NCT02092909 (Phase 1/2 Dose Escalation Study in Patients With Relapsed or Refractory Waldenstrom's Macroglobulinemia).
Investigational
Matched Synonyms: … Antagonist of the endosomal Toll-like receptors (TLRs) 7, 8, and 9 …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Anagrelide is a platelet-reducing agent used to lower dangerously elevated platelet levels (i.e. to treat thrombocythemia) in patients with myeloproliferative neoplasms. It is an oral imidazoquinazoline that was first approved for use in the US in 1997. It appears to carry a better response rate than other thrombocythemia treatments (e.g....
Approved
Matched Description: … [busulfan], [hydroxyurea]) and may be better tolerated.[A214274] …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … ANAGRELID BETA 0.5MG HARTK …
Experimental
Matched Synonyms: … daidzein 7-O-beta-D-glucoside ... 7-(beta-D-glucopyranosyloxy)-3-(4-hydroxyphenyl)-4H-chromen-4-one …
Bosentan is a dual endothelin receptor antagonist marketed under the trade name Tracleer by Actelion Pharmaceuticals. Bosentan is used to treat pulmonary hypertension by blocking the action of endothelin molecules that would otherwise promote narrowing of the blood vessels and lead to high blood pressure.
Approved
Investigational
Matched Description: … lead to high blood pressure. ... blocking the action of endothelin molecules that would otherwise promote narrowing of the blood vessels and
Matched Categories: … Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics …
Matched Products: … BOSENTAN BETA 125MG ... BOSENTAN BETA 62.5MG …
Experimental
Matched Synonyms: … guanosine 5'-[beta,gamma-methylene]triphosphate …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Pantethine is a naturally occurring compound synthesized in the body from pantothenic acid (vitamin B5) via addition of cysteamine. It consists of two molecules of pantetheine that form a dimer via disufide linkages, and acts as an intermediate in the production of Coenzyme A. Coenzyme A plays an essential role...
Approved
Investigational
Matched Synonyms: … D-Bis(N-pantothenyl-beta-aminoethyl) disulfide …
Matched Description: … Pantethine is available as a dietary supplement for lowering blood cholesterol and triglycerides. ... Coenzyme A plays an essential role as a cofactor in the metabolism of lipids and carbohydrates including ... fatty acid oxidation, carbohydrate metabolism, pyruvate degradation, and amino acid catabolism [A27255 …
Matched Categories: … Alimentary Tract and Metabolism …
Venlafaxine is an antidepressant and a serotonin and norepinephrine reuptake inhibitor (SNRI). Its active metabolite, desvenlafaxine, works by blocking the reuptake of serotonin and norepinephrine, which are key neurotransmitters in mood regulation. Venlafaxine is officially approved to treat major depressive disorder (MDD), generalized anxiety disorder (GAD), social anxiety disorder, and...
Approved
Matched Description: … Venlafaxine is an antidepressant and a serotonin and norepinephrine reuptake inhibitor (SNRI). ... Its active metabolite, [desvenlafaxine], works by blocking the reuptake of serotonin and norepinephrine ... treat major depressive disorder (MDD), generalized anxiety disorder (GAD), social anxiety disorder, and
Matched Categories: … Serotonin and Noradrenaline Reuptake Inhibitors …
Matched Products: … VENLAFAXIN BETA 37.5MG ... VENLAFAXIN BETA RET 75MG ... VENLAFAXIN BETA RET 150MG …
Buprenorphine is a weak partial mu-opioid receptor agonist and a weak kappa-opioid receptor antagonist used for the treatment of severe pain.[A186283,A186292] It is also commonly used as an alternative to methadone for the treatment of severe opioid addiction. Buprenorphine is commercially available as the brand name product Suboxone which is...
Approved
Illicit
Investigational
Vet approved
Matched Description: … reducing the reinforcing effects of opioids which can lead to drug-seeking behaviours. ... who require larger and more frequent doses. ... an improved safety profile with a lower risk of overdose and respiratory depression. …
Matched Mixtures name: … Buprenorphine and Naloxone ... Buprenorphine and Naloxone ... Buprenorphine and Naloxone …
Matched Products: … BUPRENORPHIN BETA 35UG/H ... BUPRENORPHIN BETA 70UG/H ... BUPRENORPHIN BETA 52.5UG/H …
A compound formed in the liver from ammonia produced by the deamination of amino acids. It is the principal end product of protein catabolism and constitutes about one half of the total urinary solids.
Approved
Investigational
Matched Description: … It is the principal end product of protein catabolism and constitutes about one half of the total urinary …
Matched Categories: … Blood and Blood Forming Organs ... Emollients and Protectives ... Blood Substitutes and Perfusion Solutions …
Matched Products: … BETAHA
Experimental
Matched Synonyms: … beta-Hydroxypropionic acid …
Celecoxib, a selective cyclooxygenase-2 (COX-2) inhibitor, is a nonsteroidal anti-inflammatory drug (NSAID) which is known for its decreased risk of causing gastrointestinal bleeding compared to other NSAIDS. It is used to manage symptoms of various types of arthritis pain and in familial adenomatous polyposis (FAP) to reduce precancerous polyps in...
Approved
Investigational
Matched Description: … [A181544] It is used to manage symptoms of various types of arthritis pain and in familial adenomatous ... [A181532] It is marketed by Pfizer under the brand name Celebrex, and was initially granted FDA approval ... selective COX-2 inhibitors (especially celecoxib), have been evaluated as potential cancer chemopreventive and
Matched Categories: … tramadol and celecoxib ... amlodipine and celecoxib ... Antiinflammatory and Antirheumatic Products ... Genito Urinary System and Sex Hormones ... Antineoplastic and Immunomodulating Agents …
Matched Products: … CELECOXIB BETA 100MG ... CELECOXIB BETA 200MG …
Amphetamine, a compound discovered over 100 years ago, is one of the more restricted controlled drugs. It was previously used for a large variety of conditions and this changed until this point where its use is highly restricted. Amphetamine, with the chemical formula alpha-methylphenethylamine, was discovered in 1910 and first...
Approved
Illicit
Investigational
Matched Synonyms: … beta-Aminopropylbenzene ... beta-Phenylisopropylamin …
Matched Description: … Amphetamine structure presents one chiral center and it exists in the form of dextro- and levo-isomers ... After being proven to reduce drug-induced anesthesia and produce arousal and insomnia, amphetamine racemic ... mix was registered by Smith, Kline and French in 1935. …
Matched Mixtures name: … Dextroamphetamine Saccharate and Amphetamine Aspartate and Dextroamphetamine Sulfate and Amphetamine ... Dextroamphetamine Saccharate and Amphetamine Aspartate and Dextroamphetamine Sulfate and Amphetamine ... Dextroamphetamine Saccharate and Amphetamine Aspartate and Dextroamphetamine Sulfate and Amphetamine …
Matched Categories: … Psychostimulants, Agents Used for ADHD and Nootropics …
Experimental
Matched Name: … Methyl 4-thio-beta-D-glucopyranoside …
Experimental
Matched Name: … Cytidine-5'-diphospho-beta-D-xylose …
Experimental
Matched Name: … 2'-Deoxy-thymidine-beta-L-rhamnose …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Experimental
Matched Name: … Adenosine-5'-[Beta, Gamma-Methylene]Triphosphate …
Experimental
Matched Name: … Bis-Napthyl Beta-Ketophosphonic Acid …
Experimental
Matched Name: … 1-Beta-Ribofuranosyl-1,3-Diazepinone …
Experimental
Matched Name: … beta-D-arabinofuranose 5-phosphate …
Experimental
Matched Name: … alpha-Keto-beta-methylvaleric acid …
Matched Salts name: … Calcium alpha-Keto-beta-methylvaleric acid …
Methoxy polyethylene glycol-epoetin beta is a chemically synthesised Erythropoiesis Stimulating Agent (ESA) with a longer half-life than erythropoietin. ESA is used to increase synthesis of red blood cells to treat chronic kidney disease associated anemia.
Approved
Matched Name: … Methoxy polyethylene glycol-epoetin beta
Matched Description: … Methoxy polyethylene glycol-epoetin beta is a chemically synthesised Erythropoiesis Stimulating Agent …
Matched Categories: … methoxy polyethylene glycol-epoetin beta ... Blood and Blood Forming Organs ... Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins …
Phenylalanine is an essential aromatic amino acid that is a precursor of melanin, dopamine, noradrenalin (norepinephrine), and thyroxine.
Approved
Investigational
Nutraceutical
Matched Synonyms: … beta-Phenyl-L-alanine ... (S)-alpha-Amino-beta-phenylpropionic acid …
Matched Description: … essential aromatic amino acid that is a precursor of melanin, [dopamine], [noradrenalin] (norepinephrine), and
Matched Mixtures name: … Aminosyn II and Dextrose ... Aminosyn II and Dextrose …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Ropidoxuridine is a novel, orally available, thymidine analogue and prodrug for IUdR, which demonstrated a survival advantage in Phase II studies in anaplastic astrocytoma, a type of brain tumor.
Investigational
Matched Synonyms: … 1-(2-DEOXY-.BETA.-D-ERYTHRO-PENTOFURANOSYL)-5-IODOPYRIMIDIN-2(1H)-ONE ... 2(1H)-PYRIMIDINONE, 1-(2-DEOXY-.BETA.-D-ERYTHRO-PENTOFURANOSYL)-5-IODO- …
Matched Description: … Ropidoxuridine is a novel, orally available, thymidine analogue and prodrug for IUdR, which demonstrated …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Morphine, the main alkaloid of opium, was first obtained from poppy seeds in 1805. It is a potent analgesic, though its use is limited due to tolerance, withdrawal, and the risk of abuse. Morphine is still routinely used today, though there are a number of semi-synthetic opioids of varying strength...
Approved
Investigational
Matched Description: … [A176035] It is a potent analgesic, though its use is limited due to tolerance, withdrawal, and the risk ... strength such as [codeine], [fentanyl], [methadone], [hydrocodone], [hydromorphone], [meperidine], and
Matched Categories: … morphine and antispasmodics …
Matched Products: … M BETA 10 ... M BETA 30 ... M BETA 60 …
Experimental
Matched Synonyms: … 6-Deoxy-2-O-methyl-beta-L-galactopyranose …
Matched Name: … 2-O-Methyl-beta-L-fucopyranose …
Displaying drugs 676 - 700 of 954 in total