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Displaying drugs 676 - 700 of 2141 in total
Experimental
Matched Name: … 3-((3-bromo-5-o-tolylpyrazolo[1,5-a]pyrimidin-7-ylamino)methyl)pyridine 1-oxide
Matched Iupac: … 3-({[3-bromo-5-(2-methylphenyl)pyrazolo[1,5-a]pyrimidin-7-yl]amino}methyl)pyridin-1-ium-1-olate …
Experimental
Matched Name: … Xylose-derived lactam oxime
Talditercept alfa is under investigation in clinical trial NCT03039686 (Clinical Trial to Evaluate the Efficacy, Safety, and Tolerability of RO7239361 in Ambulatory Boys With Duchenne Muscular Dystrophy).
Investigational
Matched Synonyms: … Adnectin, anti-(human growth differentiation factor 8) (synthetic clone prd-1474 fibronectin type iii ... Immunoglobulin g1 (human fc fragment) fusion protein with peptide (synthetic 17-amino acid linker) fusion …
Matched Description: … under investigation in clinical trial NCT03039686 (Clinical Trial to Evaluate the Efficacy, Safety, and
Ceftriaxone is a broad-spectrum third-generation cephalosporin antibiotic. It has a very long half-life compared to other cephalosporins and is high penetrable into the meninges , eyes , and inner ear . Ceftriaxone has broader and stronger gram-negative coverage then first or second-generation cephalosporins, but worse activity against methicillin-susceptible S.aureus. Ceftriaxone...
Approved
Matched Iupac: … (6R,7R)-7-[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetamido]-3-{[(2-methyl-5,6-dioxo-1,2,5,6 ... -tetrahydro-1,2,4-triazin-3-yl)sulfanyl]methyl}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic …
Matched Description: … meninges[A215582], eyes[A215647], and inner ear[A215627]. ... [A215582] It has a very long half-life compared to other cephalosporins and is high penetrable into the ... Ceftriaxone has broader and stronger gram-negative coverage then first or second-generation cephalosporins …
Matched Products: … Ceftriaxone and Dextrose …
Hydroxycitronellal is a synthetic fragrance that is widely used in many cosmetics and hygiene products such as deodorants, soaps, antiseptics, and other household items. It has the smell of lilac, lily, and lily of the valley . Hydroxycitronellal has also been shown to be a dermatologic irritant and allergen, and...
Approved
Experimental
Matched Synonyms: … Muguet synthetic
Matched Description: … Hydroxycitronellal is a synthetic fragrance that is widely used in many cosmetics and hygiene products ... Hydroxycitronellal has also been shown to be a dermatologic irritant and allergen, and as a result commercially ... such as deodorants, soaps, antiseptics, and other household items. …
Coagulation Factor XIII A-Subunit (Recombinant), also known as catridecacog, is a recombinant form of the Factor XIII-A2 homodimer composed of two factor XIII (FXIII) A-subunits [FDA Label]. For people with congenital deficiency or mutation of Factor XIII, a rare bleeding disorder, exogenous replacement of this key coagulation factor is essential...
Approved
Matched Synonyms: … Blood Coagulation Factor XIII (Synthetic Human A-Chain Precursor) …
Matched Description: … and maintenance of hemostasis [A18581]. ... in increased mechanical strength and resistance to fibrinolysis of the fibrin clot. ... bleeding disorder, exogenous replacement of this key coagulation factor is essential for management and
Matched Categories: … Blood and Blood Forming Organs …
Broad-spectrum cephalosporin antibiotic resistant to beta-lactamase. It has been proposed for infections with gram-negative and gram-positive organisms, gonorrhea, and haemophilus.
Approved
Matched Synonyms: … (6R,7R)-3-[(carbamoyloxy)methyl]-7-{[(2Z)-2-furan-2-yl-2-(methoxyimino)acetyl]amino}-8-oxo-5-thia-1-azabicyclo …
Matched Iupac: … (6R,7R)-3-[(carbamoyloxy)methyl]-7-[(2Z)-2-(furan-2-yl)-2-(methoxyimino)acetamido]-8-oxo-5-thia-1-azabicyclo …
Matched Description: … It has been proposed for infections with gram-negative and gram-positive organisms, gonorrhea, and haemophilus …
Matched Categories: … cefuroxime and metronidazole …
Matched Products: … Cefuroxime and Dextrose …
Experimental
Matched Name: … 4-(4-HYDROXYPHENYL)-1-NAPHTHALDEHYDE OXIME
Matched Iupac: … 4-{4-[(E)-(hydroxyimino)methyl]naphthalen-1-yl}phenol …
Vet approved
Matched Synonyms: … Methyl O-methyl-18-epireserpate …
Matched Iupac: … methyl (1R,15S,17S,18R,19S,20S)-6,17,18-trimethoxy-3,13-diazapentacyclo[11.8.0.0^{2,10}.0^{4,9}.0^{15,20 …
Experimental
Matched Synonyms: … Methyl 3-phenyl-L-alaninate ... Phenylalanine methyl ester ... (S)-phenylalanine methyl ester …
Matched Name: … methyl L-phenylalaninate …
Matched Iupac: … methyl (2S)-2-amino-3-phenylpropanoate …
Matched Categories: … Amino Acids, Peptides, and Proteins …
A cholinesterase inhibitor used in the treatment of myasthenia gravis and to reverse the effects of muscle relaxants such as gallamine and tubocurarine. Neostigmine, unlike physostigmine, does not cross the blood-brain barrier.
Approved
Vet approved
Matched Description: … relaxants such as gallamine and tubocurarine. ... A cholinesterase inhibitor used in the treatment of myasthenia gravis and to reverse the effects of muscle …
Matched Categories: … Antiglaucoma Preparations and Miotics …
Matched Products: … TÜRKTIPSAN NEOSTİGMİN METİL SÜLFAT 0.5 MG/1 ML ENJEKSİYONLUK ÇÖZELTİ, 6 ADET …
Piracetam is a nootropic drug in the racetams group, with chemical name 2-oxo-1-pyrrolidine acetamide. It shares the same 2-oxo-pyrrolidone base structure with pyroglutamic acid and is a cyclic derivative of the neurotransmitter γ-aminobutyric acid (GABA). However its mechanism of action differ from that of endogenous GABA. Piracetam has neuroprotective and...
Approved
Investigational
Matched Description: … Piracetam has neuroprotective and anticonvulsant properties and is reported to improve neural plasticity ... It shares the same 2-oxo-pyrrolidone base structure with pyroglutamic acid and is a cyclic derivative ... Its efficacy is documented in cognitive disorders and dementia, vertigo, cortical myoclonus, dyslexia …
Matched Categories: … Psychostimulants, Agents Used for ADHD and Nootropics …
Matched Products: … OXICER JARABE ... OXICER TABLETAS …
Hydroxyurea is a non-alkylating antineoplastic agent that was first synthesized in 1869 but was not characterized biologically until 1928. It was first approved by the FDA in 1998 for the treatment of sickle cell anemia in adults. Although clinical evidence on the efficacy of hydroxyurea in certain conditions exists, hydroxyurea...
Approved
Matched Synonyms: … Carbamoyl oxime
Matched Description: … adherence, the need for therapeutic monitoring, and serious side effects of secondary cancer and birth ... conditions exists, hydroxyurea is used sparingly in clinical settings, largely due to lack of knowledge and
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Nucleic Acid Synthesis Inhibitors …
Experimental
Matched Synonyms: … 4-Methyl-5-thiazolethanol ... 4-Methyl-5-thiazoleethanol ... 4-Methyl-5-hydroxethylthiazole …
Matched Iupac: … 2-(4-methyl-1,3-thiazol-5-yl)ethan-1-ol …
Gefurulimab is under investigation in clinical trial NCT05556096 (Safety and Efficacy of ALXN1720 in Adults With Generalized Myasthenia Gravis).
Investigational
Matched Synonyms: … HUMAN-LAMA GLAMA MONOCLONAL ALXN1720 SINGLE-DOMAIN VHH FRAGMENT) FUSION PROTEIN WITH PEPTIDE LINKER (SYNTHETIC
Matched Description: … Gefurulimab is under investigation in clinical trial NCT05556096 (Safety and Efficacy of ALXN1720 in …
L-NAME has been investigated for the treatment of Hypotension and Spinal Cord Injury.
Investigational
Matched Synonyms: … N-nitro-arginine methyl ester ... NG-Nitroarginine methyl ester ... NG-nitro-L-arginine methyl ester …
Matched Name: … N-omega-nitro-L-arginine methyl ester …
Matched Iupac: … methyl (2S)-2-amino-5-(N'-nitrocarbamimidamido)pentanoate …
Matched Description: … L-NAME has been investigated for the treatment of Hypotension and Spinal Cord Injury. …
Matched Categories: … Amino Acids, Peptides, and Proteins …
An inhibitor of the enzyme tyrosine 3-monooxygenase, and consequently of the synthesis of catecholamines. It is used to control the symptoms of excessive sympathetic stimulation in patients with pheochromocytoma. (Martindale, The Extra Pharmacopoeia, 30th ed)
Approved
Matched Synonyms: … α-methyl-p-tyrosine ... (–)-α-methyl-L-tyrosine ... α-methyl-L-p-tyrosine …
Matched Description: … An inhibitor of the enzyme tyrosine 3-monooxygenase, and consequently of the synthesis of catecholamines …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Catecholamine Synthesis Inhibitor …
Gimatecan is an orally available 7-t-butoxyiminomethyl-substituted lipophilic camptothecin derivative.
Investigational
Matched Synonyms: … (4S)-11-[(E)-(tert-butoxyimino)methyl]-4-ethyl-4-hydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline ... 3,4,12,14-tetrahydro-1-H-pyrano[3',4':6,7]-indolizino-[1,2-b]-quinoline-11-carbaldehyde O-(tert-butyl)-(E)-oxime ... quinoline-11-carboxaldehyde, 4-ethyl-3,4,12,14-tetrahydro-4-hydroxy-3,14-dioxo-, 11-[O-(1,1-dimethylethyl)oxime
Matched Iupac: … (19S)-10-[(1E)-[(tert-butoxy)imino]methyl]-19-ethyl-19-hydroxy-17-oxa-3,13-diazapentacyclo[11.8.0.0²,¹¹.0⁴,⁹.0¹⁵,²⁰ …
Rescinnamine is an angiotensin-converting enzyme inhibitor used as an antihypertensive drug. It is an alkaloid obtained from Rauwolfia serpentina and other species of Rauwolfia.
Approved
Matched Synonyms: … 3,4,5-Trimethoxycinnamoyl methyl reserpate ... Trimethoxy cinnamoyl reserpate de methyl
Matched Iupac: … methyl (1R,15S,17R,18R,19S,20S)-6,18-dimethoxy-17-{[3-(3,4,5-trimethoxyphenyl)prop-2-enoyl]oxy}-3,13- …
Matched Description: … It is an alkaloid obtained from _Rauwolfia serpentina_ and other species of _Rauwolfia_. …
Matched Categories: … rescinnamine and diuretics ... rescinnamine and diuretics, combinations with other drugs …
Methylparaben is used in allergenic testing.
Approved
Matched Synonyms: … Methyl paraben ... Methyl 4-hydroxybenzoate ... methyl p-hydroxybenzoate …
Matched Iupac: … methyl 4-hydroxybenzoate …
Experimental
Matched Synonyms: … 5-methyl-1H-benzimidazole ... 6-methyl-1H-benzimidazole …
Matched Iupac: … 6-methyl-1H-1,3-benzodiazole …
Experimental
Matched Synonyms: … O1-methyl-glucose ... beta-methyl-D-glucoside ... Methyl hexopyranoside …
Matched Name: … methyl beta-D-glucopyranoside …
Investigational
Matched Synonyms: … (1s,3s)-3-((2-methyl-6-(1-methyl-5-(((methyl(propyl)carbamoyl)oxy)methyl)-1h-1,2,3-triazol-4-yl)pyridin ... Cyclohexanecarboxylic acid, 3-((2-methyl-6-(1-methyl-5-((((methylpropylamino)carbonyl)oxy)methyl)-1h- …
Matched Iupac: … (1S,3S)-3-({2-methyl-6-[1-methyl-5-({[methyl(propyl)carbamoyl]oxy}methyl)-1H-1,2,3-triazol-4-yl]pyridin …
SR-9011 is a REV-ERB agonist. SR-9011 has been demonstrated that it is specifically lethal to cancer cells and oncogene-induced senescent cells, including melanocytic naevi, and has no effect on the viability of normal cells or tissues .
Experimental
Matched Synonyms: … 1-Pyrrolidinecarboxamide, 3-((((4-chlorophenyl)methyl)((5-nitro-2-thienyl)methyl)amino)methyl)-n-pentyl …
Matched Iupac: … 3-({[(4-chlorophenyl)methyl][(5-nitrothiophen-2-yl)methyl]amino}methyl)-N-pentylpyrrolidine-1-carboxamide …
Matched Description: … SR-9011 has been demonstrated that it is specifically lethal to cancer cells and oncogene-induced senescent ... cells, including melanocytic naevi, and has no effect on the viability of normal cells or tissues [A32628 …
Investigational
Matched Synonyms: … 1-((3-chloro-2-fluorophenyl)methyl)-4-((3-fluoro-6-((5-methyl-1h-pyrazol-3-yl)amino)-2-pyridinyl)methyl ... -3-yl)amino)-2-pyridinyl)methyl)-2-methyl-, (2r,4r)- ... 4-piperidinecarboxylic acid, 1-((3-chloro-2-fluorophenyl)methyl)-4-((3-fluoro-6-((5-methyl-1h-pyrazol …
Matched Iupac: … (2R,4R)-1-[(3-chloro-2-fluorophenyl)methyl]-4-({3-fluoro-6-[(5-methyl-1H-pyrazol-3-yl)amino]pyridin-2 ... -yl}methyl)-2-methylpiperidine-4-carboxylic acid …
Displaying drugs 676 - 700 of 2141 in total