Displaying drugs 676 - 700 of 799 in total
Brimonidine
Brimonidine is an alpha-adrenergic agonist and 2-imidazoline derivative that was first introduced in 1996. It is considered to be a third generation alpha-2 aadrenergic receptor agonist, since it displays preferential binding at alpha-2 adrenoceptors over alpha-1 receptors. Brimonidine displays a higher selectivity toward the alpha-2 adrenergic receptors than clonidine or...
Approved
Matched Synonyms: … 5-Bromo-6-(2-imidazolin-2-ylamino)quinoxaline …
Matched Iupac: … 5-bromo-N-(4,5-dihydro-1H-imidazol-2-yl)quinoxalin-6-amine …
Matched Description: … Brimonidine is an alpha-adrenergic agonist and 2-imidazoline derivative that was first introduced in ... Early treatment and management of glaucoma, which predominantly involves the lowering of intraocular ... Ophthalmically, brimonidine is used to lower intraocular pressure by reducing aqueous humor production and …
Matched Mixtures name: … Brimonidine Tartrate and Timolol Maleate ... BRIMONIDINE TARTRATE and TIMOLOL MALEATE ... Brimonidine Tartrate and Timolol Maleate …
Matched Categories: … Antiglaucoma Preparations and Miotics ... Decongestants and Antiallergics ... Skin and Mucous Membrane Agents …
Matched Iupac: … 5-bromo-N-(4,5-dihydro-1H-imidazol-2-yl)quinoxalin-6-amine …
Matched Description: … Brimonidine is an alpha-adrenergic agonist and 2-imidazoline derivative that was first introduced in ... Early treatment and management of glaucoma, which predominantly involves the lowering of intraocular ... Ophthalmically, brimonidine is used to lower intraocular pressure by reducing aqueous humor production and …
Matched Mixtures name: … Brimonidine Tartrate and Timolol Maleate ... BRIMONIDINE TARTRATE and TIMOLOL MALEATE ... Brimonidine Tartrate and Timolol Maleate …
Matched Categories: … Antiglaucoma Preparations and Miotics ... Decongestants and Antiallergics ... Skin and Mucous Membrane Agents …
Glycopyrronium
Glycopyrronium, also known as NVA237 or glycopyrrolate, is a racemic mixture of two enantiomers. They are both quaternary ammonium compounds and long acting muscarinic antagonists. It is one of the most commonly prescribed anticholinergic medications.[A233535,A233540] Early research into glycopyrronium use was for its indication as an adjunct therapy in the...
Approved
Investigational
Vet approved
Matched Description: … [L33110] They are both quaternary ammonium compounds and long acting muscarinic antagonists. ... found that glycopyrronium could also be used for reducing sweat gland,[L4755] oral,[L33140] airway, and ... L33105] Glycopyrronium is commonly prescribed as a first line treatment for a wide variety indications and …
Matched Categories: … Alimentary Tract and Metabolism ... indacaterol and glycopyrronium bromide ... formoterol and glycopyrronium bromide ... glycopyrronium bromide and psycholeptics ... formoterol, glycopyrronium bromide and beclometasone …
Matched Products: … GLICOPIRRONIO BROMURO ACCORD …
Matched Categories: … Alimentary Tract and Metabolism ... indacaterol and glycopyrronium bromide ... formoterol and glycopyrronium bromide ... glycopyrronium bromide and psycholeptics ... formoterol, glycopyrronium bromide and beclometasone …
Matched Products: … GLICOPIRRONIO BROMURO ACCORD …
Zolpidem
Zolpidem, also known as Ambien, is a hypnotic drug that was initially approved by the FDA in 1992 [FDA label]. Zolpidem improves sleep in patients with insomnia. It is aimed for use in patients with difficulties initiating sleep. This drug decreases the time to fall asleep (sleep latency), increases the...
Approved
Matched International brands: … Nottem …
Matched Description: … This drug decreases the time to fall asleep (sleep latency), increases the duration of sleep, and decreases ... It is available in both immediate acting and extended release forms [FDA label], [F3802]. ... according to the manufacturer’s instructions, with a low risk of drug withdrawal, drug dependence, and …
Matched Categories: … Benzodiazepine hypnotics and sedatives ... Hypnotics and Sedatives ... Miscellaneous Anxiolytics Sedatives and Hypnotics …
Matched Products: … NOTTEM …
Matched Description: … This drug decreases the time to fall asleep (sleep latency), increases the duration of sleep, and decreases ... It is available in both immediate acting and extended release forms [FDA label], [F3802]. ... according to the manufacturer’s instructions, with a low risk of drug withdrawal, drug dependence, and …
Matched Categories: … Benzodiazepine hypnotics and sedatives ... Hypnotics and Sedatives ... Miscellaneous Anxiolytics Sedatives and Hypnotics …
Matched Products: … NOTTEM …
Artemisia vulgaris root
Artemisia vulgaris root allergenic extract is used in allergenic testing.
Approved
Investigational
Matched Synonyms: … Absinthium spicatum root …
Halothane
A nonflammable, halogenated, hydrocarbon anesthetic that provides relatively rapid induction with little or no excitement. Analgesia may not be adequate. nitrous oxide is often given concomitantly. Because halothane may not produce sufficient muscle relaxation, supplemental neuromuscular blocking agents may be required. (From AMA Drug Evaluations Annual, 1994, p178)
Approved
Vet approved
Matched Synonyms: … 1-bromo-1-chloro-2,2,2-trifluoroethane ... 1,1,1-trifluoro-2-bromo-2-chloroethane ... 2-bromo-2-chloro-1,1,1-trifluoroethane …
Matched Iupac: … 2-bromo-2-chloro-1,1,1-trifluoroethane …
Matched Description: … (From AMA Drug Evaluations Annual, 1994, p178) ... may be required. ... Analgesia may not be adequate. nitrous oxide is often given concomitantly. …
Matched Iupac: … 2-bromo-2-chloro-1,1,1-trifluoroethane …
Matched Description: … (From AMA Drug Evaluations Annual, 1994, p178) ... may be required. ... Analgesia may not be adequate. nitrous oxide is often given concomitantly. …
Bromo-Willardiine
Experimental
Matched Name: … Bromo-Willardiine …
Matched Iupac: … (2S)-2-amino-3-(5-bromo-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)propanoic acid …
Matched Iupac: … (2S)-2-amino-3-(5-bromo-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)propanoic acid …
Isoprenaline
Isoprenaline is a non-selective beta adrenergic receptor agonist indicated to treat heart block, Adams-Stokes attacks, bronchospasm in anesthesia, cadiac arrest, hypovolemic shocks, septic shock, hypoperfusion, congestive hear failure, and cardiogenic shock.[A15638,L33160]
Isoprenaline research in the 1940s found that this isopropyl analog of epinephrine dilated the bronchi, as well as raising...
Approved
Investigational
Matched Description: … anesthesia, cadiac arrest, hypovolemic shocks, septic shock, hypoperfusion, congestive hear failure, and ... found that this isopropyl analog of epinephrine dilated the bronchi, as well as raising the heart rate and ... [A233724,A233729] The US patent from 1943 states that this compound had a wider therapeutic index and …
Matched Categories: … Adrenergic and Dopaminergic Agents ... isoprenaline and other drugs for obstructive airway diseases …
Matched Products: … ISOPRENALINA CLORIDRATO MAYNE PHARMA …
Matched Categories: … Adrenergic and Dopaminergic Agents ... isoprenaline and other drugs for obstructive airway diseases …
Matched Products: … ISOPRENALINA CLORIDRATO MAYNE PHARMA …
Lonicera confusa flower
Lonicera confusa flower is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Experimental
Matched Synonyms: … Lonicera Multiflora Flower …
Garlic oil
Experimental
Matched Synonyms: … Allium Sativum bulb oil …
Matched Categories: … Metabolic Side Effects of Drugs and Substances …
Matched Categories: … Metabolic Side Effects of Drugs and Substances …
Meclizine
Meclizine is a histamine H1 antagonist with antiemetic and antivertigo properties. It is used in the symptomatic treatment of motion sickness and control of vertigo associated with vestibular system diseases. It also exhibits anticholinergic, central nervous system depressant, and local anesthetic effects. Commonly marketed under the brand name Antivert in...
Approved
Matched Description: … Meclizine is a histamine H1 antagonist with antiemetic and antivertigo properties. ... It is used in the symptomatic treatment of motion sickness and control of vertigo associated with vestibular ... It also exhibits anticholinergic, central nervous system depressant, and local anesthetic effects. …
Matched Products: … Jet-Avert Motion Sickness Aid …
Matched Products: … Jet-Avert Motion Sickness Aid …
Trastuzumab
Produced in CHO cell cultures, trastuzumab is a recombinant IgG1 kappa, humanized monoclonal antibody that selectively binds with high affinity in a cell-based assay (Kd = 5 nM) to the extracellular domain of the human epidermal growth factor receptor protein (HER2). It is used as a treatment of human epidermal...
Approved
Investigational
Matched Synonyms: … trastuzumab-anns …
Matched Description: … Trastuzumab binds to HER2 and suppresses cancer cell growth, proliferation, and survival directly and ... that the overexpression or gene amplification of HER2 has been found in about 20–30% of breast cancers and ... KANJINTI (trastuzumab-anns) is another biosimilar approved by the FDA in June 2019. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... pertuzumab and trastuzumab ... MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES …
Matched Description: … Trastuzumab binds to HER2 and suppresses cancer cell growth, proliferation, and survival directly and ... that the overexpression or gene amplification of HER2 has been found in about 20–30% of breast cancers and ... KANJINTI (trastuzumab-anns) is another biosimilar approved by the FDA in June 2019. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... pertuzumab and trastuzumab ... MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES …
Brodimoprim
Experimental
Matched Synonyms: … 2,4-diamino-5-(4-bromo-3,5-dimethoxybenzyl)pyrimidine …
Matched Iupac: … 5-[(4-bromo-3,5-dimethoxyphenyl)methyl]pyrimidine-2,4-diamine …
Matched Categories: … Sulfonamides and trimethoprim ... Trimethoprim and Derivatives …
Matched Iupac: … 5-[(4-bromo-3,5-dimethoxyphenyl)methyl]pyrimidine-2,4-diamine …
Matched Categories: … Sulfonamides and trimethoprim ... Trimethoprim and Derivatives …
Camphor monobromide
Experimental
Matched Synonyms: … 3-Bromo-d-camphor …
Matched Iupac: … (1R,3S,4S)-3-bromo-1,7,7-trimethylbicyclo[2.2.1]heptan-2-one …
Matched Iupac: … (1R,3S,4S)-3-bromo-1,7,7-trimethylbicyclo[2.2.1]heptan-2-one …
Halofuginone
Halofuginone is a low molecular weight quinazolinone alkaloid, and a potent inhibitor of collagen alpha1(I) and matrix metalloproteinase 2 (MMP-2) gene expression. Halofuginone also effectively suppresses tumor progression and metastasis in mice. Collgard Biopharmaceuticals is developing halofuginone for the treatment of scleroderma and received orphan drug designation from the U.S....
Investigational
Vet approved
Matched Synonyms: … (+/-)-trans-7-bromo-6-chloro-3-(3-(3-hydroxy-2-piperidyl)-acetonyl)-4(3H)-quinazolinone …
Matched Iupac: … 7-bromo-6-chloro-3-{3-[(2R,3S)-3-hydroxypiperidin-2-yl]-2-oxopropyl}-3,4-dihydroquinazolin-4-one …
Matched Description: … (I) and matrix metalloproteinase 2 (MMP-2) gene expression. ... Halofuginone is a low molecular weight quinazolinone alkaloid, and a potent inhibitor of collagen alpha1 ... Food and Drug Administration in March, 2000. …
Matched Iupac: … 7-bromo-6-chloro-3-{3-[(2R,3S)-3-hydroxypiperidin-2-yl]-2-oxopropyl}-3,4-dihydroquinazolin-4-one …
Matched Description: … (I) and matrix metalloproteinase 2 (MMP-2) gene expression. ... Halofuginone is a low molecular weight quinazolinone alkaloid, and a potent inhibitor of collagen alpha1 ... Food and Drug Administration in March, 2000. …
Flubrobenguane F18
Investigational
Matched Synonyms: … N-((3-bromo-4-(3-(fluoro-18f)propoxy)phenyl)methyl)guanidine …
Matched Iupac: … N-({3-bromo-4-[3-(¹⁸F)fluoropropoxy]phenyl}methyl)guanidine …
Matched Iupac: … N-({3-bromo-4-[3-(¹⁸F)fluoropropoxy]phenyl}methyl)guanidine …
Vandetanib
Vandetanib is an oral once-daily kinase inhibitor of tumour angiogenesis and tumour cell proliferation with the potential for use in a broad range of tumour types.
On April 6 2011, vandetanib was approved by the FDA to treat nonresectable, locally advanced, or metastatic medullary thyroid cancer in adult patients.
Approved
Matched Synonyms: … N-(4-Bromo-2-fluorophenyl)-6-methoxy-7-((1-methyl-4-piperidinyl)methoxy)-4-quinazolinamine ... N-(4-Bromo-2-fluorophenyl)-6-methoxy-7-((1-methylpiperidin-4-yl)methoxy)quinazolin-4-amine …
Matched Iupac: … N-(4-bromo-2-fluorophenyl)-6-methoxy-7-[(1-methylpiperidin-4-yl)methoxy]quinazolin-4-amine …
Matched Description: … Vandetanib is an oral once-daily kinase inhibitor of tumour angiogenesis and tumour cell proliferation …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Iupac: … N-(4-bromo-2-fluorophenyl)-6-methoxy-7-[(1-methylpiperidin-4-yl)methoxy]quinazolin-4-amine …
Matched Description: … Vandetanib is an oral once-daily kinase inhibitor of tumour angiogenesis and tumour cell proliferation …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Depulfavirine
Depulfavirine is under investigation in clinical trial NCT05204394 (Study to Evaluate Efficacy and Safety of Switching to VM-1500A-LAI + 2nrtis From the 1st Line Standard of Care Therapy).
Investigational
Matched Synonyms: … 2-[4-Bromo-3-(3-chloro-5-cyanophenoxy)-2-fluorophenyl]-N-(2-chloro-4-sulfamoylphenyl)acetamide ... Benzeneacetamide, N-[4-(aminosulfonyl)-2-chlorophenyl]-4-bromo-3-(3-chloro-5-cyanophenoxy)-2-fluoro- …
Matched Description: … Depulfavirine is under investigation in clinical trial NCT05204394 (Study to Evaluate Efficacy and Safety …
Matched Description: … Depulfavirine is under investigation in clinical trial NCT05204394 (Study to Evaluate Efficacy and Safety …
WP-1066
WP1066 has been used in trials studying the treatment of Melanoma, Brain Cancer, Solid Tumors, and Central Nervous System Neoplasms.
Investigational
Matched Synonyms: … (E)-3-(6-Bromo-pyridin-2-yl)-2-cyano-N-((S)-1-phenyl-ethyl)-acryl amide ... 2-PROPENAMIDE, 3-(6-BROMO-2-PYRIDINYL)-2-CYANO-N-((1S)-1-PHENYLETHYL)-, (2E)- …
Matched Description: … WP1066 has been used in trials studying the treatment of Melanoma, Brain Cancer, Solid Tumors, and Central …
Matched Description: … WP1066 has been used in trials studying the treatment of Melanoma, Brain Cancer, Solid Tumors, and Central …
Bromopride
Bromopride is a dopamine antagonist used as an antiemetic. Its prokinetic properties are similar to those of metoclopramide. It is unavailable in America or the United Kingdom.
Investigational
Matched Synonyms: … 4-amino-5-bromo-N-[2-(diethylamino)ethyl]-2-methoxybenzamide …
Matched Iupac: … 4-amino-5-bromo-N-[2-(diethylamino)ethyl]-2-methoxybenzamide …
Matched Categories: … Alimentary Tract and Metabolism ... Benzamides and benzamide derivatives …
Matched Iupac: … 4-amino-5-bromo-N-[2-(diethylamino)ethyl]-2-methoxybenzamide …
Matched Categories: … Alimentary Tract and Metabolism ... Benzamides and benzamide derivatives …
Exagamglogene autotemcel
Sickle cell disease (SCD) is a genetic disorder characterized by the production of abnormal sickle-shaped red blood cells (called hemoglobin S, HbS) that initiate a pathophysiology resulting in severe pain, progressive multi-organ damage, and premature death. Treatment options for SCD are largely focused on preventing the production and circulation of...
Approved
Investigational
Matched Synonyms: … blood by positive selection, modified by CRISPR/Cas9 (clustered regularly interspaced short palindromic repeats …
Matched Description: … hemoglobin S, HbS) that initiate a pathophysiology resulting in severe pain, progressive multi-organ damage, and ... [A262691] Treatment options for SCD are largely focused on preventing the production and circulation ... of HbS and inducing the production of normal fetal hemoglobin (HbF),[A262696,A262701] including [hydroxyurea …
Matched Categories: … Blood and Blood Forming Organs …
Matched Description: … hemoglobin S, HbS) that initiate a pathophysiology resulting in severe pain, progressive multi-organ damage, and ... [A262691] Treatment options for SCD are largely focused on preventing the production and circulation ... of HbS and inducing the production of normal fetal hemoglobin (HbF),[A262696,A262701] including [hydroxyurea …
Matched Categories: … Blood and Blood Forming Organs …
Fordadistrogene movaparvovec
Investigational
Matched Synonyms: … MUSCLE-SPECIFIC ENHANCER/PROMOTER PLUS HUMAN MINI-DYSTROPHIN GENE PLUS ADENO-ASSOCIATED VIRUS 9 INVERTED TERMINAL REPEAT …
Displaying drugs 676 - 700 of 799 in total