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Displaying drugs 701 - 725 of 1917 in total
Gepirone, an azapirone, is a pharmacologic analog of buspirone that acts selectively on the pre- and post-synaptic 5HT1A receptors. Although earlier clinical trials showed promising results for gepirone, its formulation as an immediate-release tablet necessitates frequent administration due to the short half-lives. It was not until an extended-release formulation of...
Approved
Investigational
Matched Salts cas: … 83928-66-9
Pseudoephedrine is structurally related to ephedrine but exerts a weaker effect on the sympathetic nervous system.[A188820,A188823] Both drugs naturally occur in in ephedra plant which have a history of use in traditional Eastern medicine and were first researched in the west in 1889. The decongestant effect of pseudoephedrine was described...
Approved
Matched Mixtures name: … Zodryl DAC 35 ... Zodryl DEC 35
An anthracycline which is the 4'-epi-isomer of doxorubicin. The compound exerts its antitumor effects by interference with the synthesis and function of DNA.
Approved
Novartis' brand name Zelnorm (tegaserod) had originally received approval from the US FDA in 2002 for the treatment of irritable bowel syndrome with constipation (IBS-C).[L5918,F4229] It was, however, voluntarily withdrawn from widespread use in the US market in 2007 after concerns arose over the possibility that tegaserod could potentially cause...
Approved
Investigational
Withdrawn
Omacetaxine mepesuccinate (formerly known as HHT or Homoharringtonine), is a cephalotaxine ester and protein synthesis inhibitor with established clinical activity as a single agent in hematological malignancies. Omacetaxine mepesuccinate is synthesized from cephalotaxine, which is an extract from the leaves of the plant, Cephalotaxus species. In October 2005, omacetaxine mepesuccinate...
Approved
Investigational
Polymyxin B was discovered in the 1940s . They are basic polypeptides of about eight amino acids and have cationic detergent action on cell membranes . Polymyxin B is used for infections with gram-negative organisms, but may be neurotoxic and nephrotoxic[A176426,FDA Label]. All gram-positive bacteria, fungi, and the gram-negative cocci,...
Approved
Vet approved
Matched Mixtures name: … DAYMARK FAK-35 First Aid …
Methyl salicylate (oil of wintergreen or wintergreen oil) is an organic ester naturally produced by many species of plants, particularly wintergreens. The compound was first extracted and isolated from plant species Gaultheria procumbens in 1843. It can be manufactured synthetically and it used as a fragrance, in foods, beverages, and...
Approved
Vet approved
Matched Mixtures name: … LINIMENTO VENECIANO Nº 9
Aluminum zirconium octachlorohydrex gly is complex that consists of aluminum zirconium octachlorohydrate and glycine. It is an active antiperspirant agent , . It diffuses into the sweat pores and prevents perspiration (sweat) from leaving the pores. The anhydrous form of the compound also has water-absorbing properties. Currently, the FDA allows...
Approved
Matched Products: … studio 35 beauty Clinical Strength …
Bupropion (also known as the brand name product Wellbutrin®) is a norepinephrine/dopamine-reuptake inhibitor (NDRI) used most commonly for the management of Major Depressive Disorder (MDD), Seasonal Affective Disorder (SAD), and as an aid for smoking cessation. Bupropion exerts its pharmacological effects by weakly inhibiting the enzymes involved in the uptake...
Approved
An aromatic ether that is phenol which is substituted at C-5 by a chloro group and at C-2 by a 2,4-dichlorophenoxy group. It is widely used as a preservative and antimicrobial agent in personal care products such as soaps, skin creams, toothpaste and deodorants as well as in household items...
Approved
Investigational
Matched Products: … Studio 35 Spring Morning …
A compound obtained from the bark of the white willow and wintergreen leaves, and also prepared synthetically. It has bacteriostatic, fungicidal, and keratolytic actions. Its salts, the salicylates, are used as analgesics.
Approved
Investigational
Vet approved
Matched Salts cas: … 578-36-9
Matched Products: … CLEAR AND COVER ACNE TREATMENT CONCEALER CLEAR AND COVER ACNE TREATMENT CONCEALER 9 almond …
Experimental
Matched Synonyms: … 9-phenanthrenamine ... 9-phenanthrylamine ... phenanthren-9-amine …
Matched Name: … 9-Aminophenanthrene …
Matched Iupac: … phenanthren-9-amine …
Investigational
Matched Synonyms: … 3,4,5-piperidinetriol, 2-(hydroxymethyl)-1-(9-methoxynonyl)-, (2r,3r,4r,5s)- …
Matched Name: … N-9-Methoxynonyldeoxynojirimycin …
Matched Iupac: … (2R,3R,4R,5S)-2-(hydroxymethyl)-1-(9-methoxynonyl)piperidine-3,4,5-triol …
Matched Salts name: … N-9-Methoxynonyldeoxynojirimycin hydrochloride …
Experimental
Matched Synonyms: … (9S,10E,12Z)-9-hydroxyoctadeca-10,12-dienoic acid …
Matched Name: … 9(S)-HODE …
Matched Iupac: … (9S,10E,12Z)-9-hydroxyoctadeca-10,12-dienoic acid …
Experimental
Matched Name: … 9-Deazaguanine …
Experimental
Matched Synonyms: … 9-Hydroxypropyladenine, S-Isomer …
Matched Name: … S-9-(2-hydroxypropyl)adenine …
Matched Iupac: … (2S)-1-(6-amino-9H-purin-9-yl)propan-2-ol …
Experimental
Matched Synonyms: … 9-Hydroxypropyladenine, R-Isomer …
Matched Name: … R-9-(2-hydroxypropyl)adenine …
Matched Iupac: … (2R)-1-(6-amino-9H-purin-9-yl)propan-2-ol …
Pivaloyloxymethyl butyrate (AN-9), an acyloxyalkyl ester prodrug of butyric acid (BA), exhibited low toxicity and significant anticancer activity in vitro and in vivo. It shows greater potency than BA at inducing malignant cell differentiation and tumor growth inhibition and has demonstrated more favorable toxicological, pharmacological, and pharmaceutical properties than BA...
Investigational
Matched Name: … AN-9
Matched Description: … Pivaloyloxymethyl butyrate (AN-9), an acyloxyalkyl ester prodrug of butyric acid (BA), exhibited low …
Investigational
Matched Name: … AKV-9
Experimental
Matched Name: … 9-Methylguanine …
Matched Iupac: … 2-amino-9-methyl-6,9-dihydro-1H-purin-6-one …
Experimental
Matched Name: … 9-deazainosine …
Experimental
Matched Name: … 9-Deazahypoxanthine …
Aminocamptothecin has been used in trials studying the treatment of Lymphoma, Gastric Cancer, Ovarian Cancer, Esophageal Cancer, and Ovarian Neoplasms, among others.
Investigational
Matched Name: … 9-aminocamptothecin …
Experimental
Matched Synonyms: … 3-(10-methyl-9-anthryl)propionic acid ... 3-(10-METHYL-ANTHRACEN-9-YL)-PROPIONIC ACID …
Matched Name: … 3-(10-methyl-9-anthryl)propanoic acid …
Matched Iupac: … 3-(10-methylanthracen-9-yl)propanoic acid …
Experimental
Matched Name: … 9-Methyl Uric Acid …
Matched Iupac: … 9-methyl-2,3,6,7,8,9-hexahydro-1H-purine-2,6,8-trione …
Displaying drugs 701 - 725 of 1917 in total