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Displaying drugs 701 - 725 of 2776 in total
Chemically, dantrolene is a hydantoin derivative, but does not exhibit antiepileptic activity like other hydantoin derivates such as phenytoin.
Approved
Investigational
Matched Salts name: … Dantrolene sodium
Matched Categories: … Dantrolene and Derivatives …
Matched Products: … Dantrolene Sodium ... RYANODEX dantrolene sodium ... Dantrolene Sodium for Injection, USP …
Izuralimab is under investigation in clinical trial NCT05879185 (A Study of Xmab23104 in People With Sarcoma).
Investigational
Matched Synonyms: … INDUCIBLE T-CELL COSTIMULATORY, ACTIVATION-INDUCIBLE LYMPHOCYTE IMMUNOMEDIATORY MOLECULE, AILIM, CD278)) AND
A complex of gadolinium with a chelating agent, diethylenetriamine penta-acetic acid (DTPA see pentetic acid), that is given to enhance the image in cranial and spinal MRIs. (From Martindale, The Extra Pharmacopoeia, 30th ed, p706)
Approved
Matched Synonyms: … Acide gadopentetique ... Gadopentetic acid ... Acidum gadopenteticum …
Matched Name: … Gadopentetic acid
Matched Description: … acid), that is given to enhance the image in cranial and spinal MRIs. ... A complex of gadolinium with a chelating agent, diethylenetriamine penta-acetic acid (DTPA see pentetic …
Matched Categories: … Acids, Acyclic ... Carboxylic Acids ... gadopentetic acid
Matched Products: … ACIDO GADOPENTETICO SANOCHEMIA PHARMAZEUTIKA …
Argatroban is a direct, selective thrombin inhibitor. The American College of Cardiologists (ACC) recommend using bivalirudin or argatroban in patients who have had, or at risk for, heparin induced thrombocytopenia (HIT) and are undergoing percutaneous coronary intervention. Argatroban is a non-heparin anticoagulant shown to both normalize platelet count in patients...
Approved
Investigational
Matched Synonyms: … Argatroban anhydrous
Matched Iupac: … carbamimidamido-2-(3-methyl-1,2,3,4-tetrahydroquinoline-8-sulfonamido)pentanoyl]-4-methylpiperidine-2-carboxylic acid
Matched Description: … bivalirudin or argatroban in patients who have had, or at risk for, heparin induced thrombocytopenia (HIT) and ... Parental anticoagulants must be stopped and a baseline activated partial thromboplastin time must be ... Argatroban is a non-heparin anticoagulant shown to both normalize platelet count in patients with HIT and
Matched Salts name: … Argatroban monohydrate
Matched Categories: … Amino Acids, Peptides, and Proteins ... Blood and Blood Forming Organs ... Amino Acids ... Acids, Heterocyclic ... Amino Acids, Basic …
Regadenoson is an A2A adenosine receptor agonist that causes coronary vasodilation and used for myocardial perfusion imagining. Manufactured by Astellas and FDA approved April 10, 2008.
Approved
Investigational
Matched Synonyms: … Regadenoson anhydrous
Matched Description: … Manufactured by Astellas and FDA approved April 10, 2008. ... Regadenoson is an A2A adenosine receptor agonist that causes coronary vasodilation and used for myocardial …
Matched Salts name: … Regadenoson monohydrate
Enalaprilat is the active metabolite of the orally available pro-drug, enalapril. Used in the treatment of hypertension, enalapril is an ACE inhibitor that prevents Angiotensin Converting Enzyme (ACE) from transforming angiotensin I into angiotensin II. As angiotensin II is responsible for vasoconstriction and sodium reabsorption in the proximal tubule of...
Approved
Matched Synonyms: … Enalaprilat anhydrous
Matched Iupac: … (2S)-1-[(2S)-2-{[(1S)-1-carboxy-3-phenylpropyl]amino}propanoyl]pyrrolidine-2-carboxylic acid
Matched Description: … As angiotensin II is responsible for vasoconstriction and sodium reabsorption in the proximal tubule ... of the kidney, down-regulation of this protein results in reduced blood pressure and blood fluid volume ... to overcome the limitations of the first ACE inhibitor, captopril, which had numerous side effects and
Matched Salts name: … Enalaprilat dihydrate
Matched Categories: … Amino Acids, Peptides, and Proteins …
Tofogliflozin has been used in trials studying the treatment and prevention of Diabetes Mellitus Type 2.
Investigational
Matched Synonyms: … Tofogliflozin anhydrous
Matched Description: … Tofogliflozin has been used in trials studying the treatment and prevention of Diabetes Mellitus Type …
Matched Categories: … Sodium-Glucose Transporter 2 Inhibitors …
Relebactam is a diazabicyclooctane beta-lactamase inhibitor, similar in structure to avibactam.[A181195,A181207] It includes a piperidine ring which reduces export from bacterial cells by producing a positive charge. It is currently available in a combination product which includes imipenem and cilastatin to treat complicated urinary tract infections (UTIs), pyelonephritis, and complicated...
Approved
Investigational
Matched Synonyms: … Relebactam anhydrous
Matched Iupac: … [(1R,2S,5R)-7-oxo-2-[(piperidin-4-yl)carbamoyl]-1,6-diazabicyclo[3.2.1]octan-6-yl]oxidanesulfonic acid
Matched Description: … [A181207] It is currently available in a combination product which includes [imipenem] and [cilastatin ... ] to treat complicated urinary tract infections (UTIs), pyelonephritis, and complicated intra-abdominal ... [label] It is considered to be a last-line treatment option and gained FDA approval as part of the combination …
Matched Salts name: … Relebactam sodium
Matched Categories: … imipenem, cilastatin and relebactam …
Ascorbyl phosphate is a synthetic form of Vitamin C and is found in different salt forms such as magnesium ascorbyl phosphate and sodium ascorbyl phosphate. These salts are present in cosmetic products at concentrations ranging from 0.001 % to 3% . As vitamin C is susceptible to breakdown of compound...
Approved
Matched Name: … Ascorbyl phosphate
Matched Description: … ascorbyl phosphate and sodium ascorbyl phosphate. ... Ascorbyl phosphate is a synthetic form of Vitamin C and is found in different salt forms such as magnesium ... phosphate, along with other Vitamin C derivatives, acts as an active and stable precursor of vitamin …
Matched Salts name: … Magnesium ascorbyl phosphate
Matched Categories: … Vitamin C and analogues ... Sugar Acids ... Acids, Acyclic ... Hydroxy Acids ... Carboxylic Acids
Oxygen is an element displayed by the symbol O, and atomic number 8. It is an essential element for human survival. Decreased oxygen levels may be treated with medical oxygen therapy. Treatment with oxygen serves to increase blood oxygen levels and also exerts a secondary effect of decreasing blood flow...
Approved
Vet approved
Matched Description: … Oxygen is an element displayed by the symbol O, and atomic number 8. ... any disease that impairs the body's ability to take up and use gaseous oxygen. ... Treatment with oxygen serves to increase blood oxygen levels and also exerts a secondary effect of decreasing …
Matched Mixtures name: … Carbon Dioxide and Oxygen Mixture, Compressed, Oxidizing, N.O.S. …
Matched Products: … OSSIGENO FARMA GAS MEDICAL AND TECHNICAL GASES …
Calcium chloride is an ionic compound of calcium and chlorine. It is highly soluble in water and it is deliquescent. It is a salt that is solid at room temperature, and it behaves as a typical ionic halide. It has several common applications such as brine for refrigeration plants, ice...
Approved
Matched Synonyms: … Calcium chloride anhydrous ... Calcium chloride, anhydrous
Matched Description: … , and in cement. ... It is highly soluble in water and it is deliquescent. ... Calcium chloride is an ionic compound of calcium and chlorine. …
Matched Mixtures name: … Ringers and Dextrose ... Plasma-Lyte M and Dextrose ... Ringers and Dextrose
Matched Salts name: … Calcium chloride dihydrate
Matched Categories: … ascorbic acid (vit C) and calcium ... Alimentary Tract and Metabolism ... Blood and Blood Forming Organs ... Blood Substitutes and Perfusion Solutions ... Genito Urinary System and Sex Hormones …
Experimental
Matched Name: … D-Gluco-2,5-Anhydro-1-Deoxy-1-Phosphonohexitol-6-Phosphate
Matched Iupac: … {[(2R,3S,4S,5R)-3,4-dihydroxy-5-(phosphonomethyl)oxolan-2-yl]methoxy}phosphonic acid
A dextrodisaccharide from malt and starch. It is used as a sweetening agent and fermentable intermediate in brewing (Grant & Hackh's Chemical Dictionary, 5th ed).
Experimental
Investigational
Matched Synonyms: … Maltose anhydrous
Matched Description: … A dextrodisaccharide from malt and starch. ... It is used as a sweetening agent and fermentable intermediate in brewing (Grant & Hackh's Chemical …
Matched Categories: … Diet, Food, and Nutrition …
Gadodiamide is a linear, non-ionic gadolinium-based contrast agent (GBCA) that is used in magnetic resonance imaging (MRI) procedures to assist in the visualization of blood vessels.[A263086,A263091] GBCAs constitute the largest group of MR agents, and they are thought to be safer than nonionic iodinated contrast agents. Approved by the FDA...
Approved
Investigational
Matched Synonyms: … Gadodiamide anhydrous
Matched Description: … [A263086,A263091] GBCAs constitute the largest group of MR agents, and they are thought to be safer than ... macrocyclic or ionic GBCA, gadodiamide can potentially lead to more gadolinium retention in the brain and
Matched Categories: … Acids, Acyclic ... Carboxylic Acids
A 2-phosphoglyceric acid in which the glyceric acid moiety has D (R) configuration.
Experimental
Matched Synonyms: … D-glycerate 2-phosphate
Matched Name: … 2-phospho-D-glyceric acid
Matched Iupac: … (2R)-3-hydroxy-2-(phosphonooxy)propanoic acid
Matched Description: … A 2-phosphoglyceric acid in which the glyceric acid moiety has D (R) configuration. …
Stearic acid (IUPAC systematic name: octadecanoic acid) is one of the useful types of saturated fatty acids that comes from many animal and vegetable fats and oils. It is a waxy solid.
Approved
Experimental
Matched Synonyms: … Acide stéarique ... Stearic acid ... Octadecoic acid
Matched Name: … Stearic acid
Matched Iupac: … octadecanoic acid
Matched Description: … acids that comes from many animal and vegetable fats and oils. ... Stearic acid (IUPAC systematic name: octadecanoic acid) is one of the useful types of saturated fatty …
Matched Categories: … Fatty Acids ... Stearic Acids
A chelating agent (chelating agents) that sequesters a variety of polyvalent cations. It is used in pharmaceutical manufacturing and as a food additive.
Approved
Vet approved
Matched Synonyms: … Edetic acid ... Acido edetico ... Acide edetique …
Matched Name: … Edetic acid
Matched Iupac: … 2-({2-[bis(carboxymethyl)amino]ethyl}(carboxymethyl)amino)acetic acid
Matched Description: … It is used in pharmaceutical manufacturing and as a food additive. …
Matched Categories: … Diet, Food, and Nutrition ... Acids, Acyclic ... Carboxylic Acids
Matched Products: … SODIO EDETATO MONICO ... SODIO EDETATO S.A.L.F. ... SODIO EDETATO GALENICA SENESE …
Experimental
Matched Synonyms: … Potassium glycerophosphate anhydrous
Hydroxocobalamin, also known as vitamin B12a and hydroxycobalamin, is an injectable form of vitamin B 12 that has been used therapeutically to treat vitamin B 12 deficiency. It is also used in cyanide poisoning, Leber's optic atrophy, and toxic amblyopia.
Approved
Matched Synonyms: … Hydroxocobalamin anhydrous ... Hydroxocobalaminum anhydrous
Matched Iupac: … undecamethyl-15,20-dioxo-11,14,16-trioxa-2lambda5,9,19,26,43lambda5,44lambda5,45lambda5-heptaaza-15lambda5-phospha
Matched Description: … It is also used in cyanide poisoning, Leber's optic atrophy, and toxic amblyopia. ... Hydroxocobalamin, also known as vitamin B12a and hydroxycobalamin, is an injectable form of vitamin B …
Matched Categories: … Vitamin B12 and Folic Acid ... Blood and Blood Forming Organs …
Experimental
Matched Synonyms: … beta-galactose-6-phosphate
Matched Name: … beta-D-galactose 6-phosphate
Matched Iupac: … {[(2R,3R,4S,5R,6R)-3,4,5,6-tetrahydroxyoxan-2-yl]methoxy}phosphonic acid
OXI-4503 is investigated in clinical trials for treating cancer/tumors. OXI-4503 is a solid. OXI-4503 blocks and destroys tumor vasculature, resulting in extensive tumor cell death and necrosis. OXI-4503 (combretastatin A1 di-phosphate / CA1P) is a unique and highly potent, dual-mechanism vascular disrupting agent (VDA). In addition, however, preclinical data demonstrates...
Investigational
Matched Synonyms: … Combretastatin A-1 bis(phosphate) …
Matched Iupac: … [3-methoxy-2-(phosphonooxy)-6-[(Z)-2-(3,4,5-trimethoxyphenyl)ethenyl]phenoxy]phosphonic acid
Matched Description: … OXI-4503 (combretastatin A1 di-phosphate / CA1P) is a unique and highly potent, dual-mechanism vascular ... OXI-4503 blocks and destroys tumor vasculature, resulting in extensive tumor cell death and necrosis. ... , preclinical data demonstrates that OXI-4503 is metabolized by oxidative enzymes (e.g., tyrosinase and
Matched Categories: … Phosphate salts ... Acids ... Acids, Noncarboxylic ... Phosphoric Acids ... Phosphorus Acids
Fosphenytoin is a water-soluble phenytoin prodrug used only in hospitals for the treatment of epileptic seizures. It works by slowing down impulses in the brain that cause seizures. Its main mechanism is to block frequency-dependent, use-dependent and voltage-dependent neuronal sodium channels, and therefore limit repetitive firing of action potentials.
Approved
Investigational
Matched Iupac: … [(2,5-dioxo-4,4-diphenylimidazolidin-1-yl)methoxy]phosphonic acid
Matched Description: … Its main mechanism is to block frequency-dependent, use-dependent and voltage-dependent neuronal sodium ... channels, and therefore limit repetitive firing of action potentials. …
Matched Salts name: … Fosphenytoin sodium
Matched Categories: … Phenytoin and Prodrugs ... Sodium Channel Blockers …
Matched Products: … Fosphenytoin Sodium ... Fosphenytoin sodium
Experimental
Matched Name: … Paratoulene phosphate
Matched Iupac: … 3S)-1-({[1,1'-biphenyl]-4-yl}methyl)-2-oxoazepan-3-yl]carbamoyl}-2-acetamidoethyl]phenoxy}phosphonic acid
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids ... Amino Acids, Cyclic ... Amino Acids, Aromatic ... Phosphoamino Acids
Secobarbital (marketed by Eli Lilly and Company under the brand names Seconal and Tuinal) is a barbiturate derivative drug with anaesthetic, anticonvulsant, sedative and hypnotic properties. It is commonly known as quinalbarbitone in the United Kingdom.
Approved
Vet approved
Matched Synonyms: … 5-allyl-5-(1-methylbutyl)barbituric acid
Matched Description: … Secobarbital (marketed by Eli Lilly and Company under the brand names Seconal and Tuinal) is a barbiturate ... derivative drug with anaesthetic, anticonvulsant, sedative and hypnotic properties. …
Matched Salts name: … Secobarbital sodium
Matched Categories: … Hypnotics and Sedatives …
Matched Products: … Seconal Sodium ... Seconal Sodium Pulvule 240 0.1gm …
Tienilic acid, or ticrynafen, is a diuretic drug with uric acid-lowering action which was marketed for the treatment of hypertension. It was withdrawn in 1982 after case reports in the United States suggested a link between ticrynafen and hepatitis. (Manier et al., 1982)
Withdrawn
Matched Synonyms: … Tienilic acid ... Thienylic acid ... Acide tiénilique …
Matched Name: … Tienilic acid
Matched Iupac: … 2-[2,3-dichloro-4-(thiophene-2-carbonyl)phenoxy]acetic acid
Matched Description: … It was withdrawn in 1982 after case reports in the United States suggested a link between ticrynafen and ... Tienilic acid, or ticrynafen, is a diuretic drug with uric acid-lowering action which was marketed for …
Matched Categories: … Acids, Acyclic ... Carboxylic Acids ... Hydroxy Acids ... tienilic acid ... Aryloxyacetic Acid Derivatives …
Displaying drugs 701 - 725 of 2776 in total