Displaying drugs 701 - 725 of 1964 in total
Isoliquiritigenin
Isoliquiritigenin is a precursor to several flavonones in many plants.
Experimental
Matched Synonyms: … (E)-1-(2,4-Dihydroxy-phenyl)-3-(4-hydroxy-phenyl)-propenone …
Balsalazide
Balsalazide is an anti-inflammatory drug used in the treatment of Inflammatory Bowel Disease. It is sold under the name "Colazal" in the US and "Colazide" in the UK.
The chemical name is (E)-5-[[-4-(2-carboxyethyl) aminocarbonyl] phenyl]azo] -2-hydroxybenzoic acid. It is usually administered as the disodium salt.
Balsalazide works by deliverying mesalazine...
Approved
Investigational
Matched Synonyms: … (E)-5-({p-[(2-carboxyethyl)carbamoyl]phenyl}azo)-2-salicylic acid ... (E)-5-((4-(((2-carboxyethyl)amino)carbonyl)phenyl)azo)-2-hydroxybenzoic acid ... 3-(2-{4-[(2-carboxyethyl)carbamoyl]phenyl}hydrazinylidene)-6-oxocyclohexa-1,4-diene-1-carboxylic acid …
Matched Iupac: … 5-[(1E)-2-{4-[(2-carboxyethyl)carbamoyl]phenyl}diazen-1-yl]-2-hydroxybenzoic acid …
Matched Description: … It is sold under the name "Colazal" in the US and "Colazide" in the UK. ... The chemical name is (E)-5-[[-4-(2-carboxyethyl) aminocarbonyl] phenyl]azo] -2-hydroxybenzoic acid. …
Matched Categories: … Alimentary Tract and Metabolism ... Phenols …
Matched Iupac: … 5-[(1E)-2-{4-[(2-carboxyethyl)carbamoyl]phenyl}diazen-1-yl]-2-hydroxybenzoic acid …
Matched Description: … It is sold under the name "Colazal" in the US and "Colazide" in the UK. ... The chemical name is (E)-5-[[-4-(2-carboxyethyl) aminocarbonyl] phenyl]azo] -2-hydroxybenzoic acid. …
Matched Categories: … Alimentary Tract and Metabolism ... Phenols …
Dexlansoprazole
Dexlansoprazole is a new-generation proton pump inhibitor (PPI) used for the management of symptoms associated with gastroesophageal reflux disease (GERD) and erosive esophagitis. Dexlansoprazole is the R-enantiomer of DB00448, which is composed of a racemic mixture of the R- and S-enantiomers. Compared to the older generation of PPIs (which includes...
Approved
Investigational
Matched Synonyms: … LANSOPRAZOLE R-FORM …
Matched Description: … the need for meal-associated dosing. ... with gastroesophageal reflux disease (GERD) and erosive esophagitis. ... Dexlansoprazole is the R-enantiomer of [DB00448], which is composed of a racemic mixture of the R- and …
Matched Categories: … Drugs for Peptic Ulcer and Gastro-Oesophageal Reflux Disease (Gord) ... Alimentary Tract and Metabolism ... Drugs for Acid Related Disorders …
Matched Description: … the need for meal-associated dosing. ... with gastroesophageal reflux disease (GERD) and erosive esophagitis. ... Dexlansoprazole is the R-enantiomer of [DB00448], which is composed of a racemic mixture of the R- and …
Matched Categories: … Drugs for Peptic Ulcer and Gastro-Oesophageal Reflux Disease (Gord) ... Alimentary Tract and Metabolism ... Drugs for Acid Related Disorders …
Spebrutinib
Spebrutinib has been used in trials studying the treatment of Rheumatoid Arthritis, Lymphoma, Large B-Cell, Diffuse, and Leukemia Lymphocytic Chronic B-Cell.
Investigational
Matched Synonyms: … 3-(5-FLUORO-2-(4-(2-METHOXYETHOXY)PHENYLAMINO)PYRIMIDIN-4-YLAMINO)PHENYL)ACRYLAMIDE ... N-(3-(5-fluoro-2-(4-(2-methoxyethoxy)phenylamino)pyrimidin-4-ylamino)phenyl)acrylamide …
Matched Iupac: … N-{3-[(5-fluoro-2-{[4-(2-methoxyethoxy)phenyl]amino}pyrimidin-4-yl)amino]phenyl}prop-2-enamide …
Matched Description: … been used in trials studying the treatment of Rheumatoid Arthritis, Lymphoma, Large B-Cell, Diffuse, and …
Matched Iupac: … N-{3-[(5-fluoro-2-{[4-(2-methoxyethoxy)phenyl]amino}pyrimidin-4-yl)amino]phenyl}prop-2-enamide …
Matched Description: … been used in trials studying the treatment of Rheumatoid Arthritis, Lymphoma, Large B-Cell, Diffuse, and …
Clomifene
A triphenyl ethylene stilbene derivative which is an estrogen agonist or antagonist depending on the target tissue.
Approved
Investigational
Matched Synonyms: … 2-(p-(β-chloro-α-phenylstyryl)phenoxy)triethylamine ... 2-(p-(2-chloro-1,2-diphenylvinyl)phenoxy)triethylamine ... 2-(4-(2-chloro-1,2-diphenylethenyl)phenoxy)-N,N-diethylethanamine …
Matched Iupac: … {2-[4-(2-chloro-1,2-diphenylethenyl)phenoxy]ethyl}diethylamine …
Matched Categories: … Ovulation Stimulants, Synthetic ... Genito Urinary System and Sex Hormones ... Hormones, Hormone Substitutes, and Hormone Antagonists ... Sex Hormones and Modulators of the Genital System …
Matched Iupac: … {2-[4-(2-chloro-1,2-diphenylethenyl)phenoxy]ethyl}diethylamine …
Matched Categories: … Ovulation Stimulants, Synthetic ... Genito Urinary System and Sex Hormones ... Hormones, Hormone Substitutes, and Hormone Antagonists ... Sex Hormones and Modulators of the Genital System …
Benzydamine
Benzydamine (also known as Tantum Verde or Difflam), available as the hydrochloride salt, is a locally-acting nonsteroidal anti-inflammatory drug (NSAID) with local anaesthetic and analgesic properties. It is used topically for pain relief and anti-inflammatory treatment of the mouth, throat, or muscoskeletal system.
Although the indazole analogue benzydamine is a...
Approved
Matched Description: … It is used topically for pain relief and anti-inflammatory treatment of the mouth, throat, or muscoskeletal ... hydrochloride salt, is a locally-acting nonsteroidal anti-inflammatory drug (NSAID) with local anaesthetic and ... benzydamine is a non-steroidal anti-inflammatory drug (NSAID), it has various physicochemical properties and …
Matched Mixtures name: … Anti-inflammatory Lozenge (with antibacterial) (Eucalyptus and Menthol) ... Difflam plus ANAESTHETIC Sore Throat Lozenges (Sugar Free) Menthol and Eucalyptus Flavour ... FARHEX FORTE SPREY …
Matched Categories: … Topical Products for Joint and Muscular Pain ... Alimentary Tract and Metabolism ... Mouthwashes and Gargles ... Antiinflammatory and Antirheumatic Products ... Genito Urinary System and Sex Hormones …
Matched Products: … Tantum Verde forte - Mundspray ... BENZIRIN® FORTE 0.3% SOLUCIÓN BUCAL ... Difflam Forte Anti-Inflammatory Throat Spray …
Matched Mixtures name: … Anti-inflammatory Lozenge (with antibacterial) (Eucalyptus and Menthol) ... Difflam plus ANAESTHETIC Sore Throat Lozenges (Sugar Free) Menthol and Eucalyptus Flavour ... FARHEX FORTE SPREY …
Matched Categories: … Topical Products for Joint and Muscular Pain ... Alimentary Tract and Metabolism ... Mouthwashes and Gargles ... Antiinflammatory and Antirheumatic Products ... Genito Urinary System and Sex Hormones …
Matched Products: … Tantum Verde forte - Mundspray ... BENZIRIN® FORTE 0.3% SOLUCIÓN BUCAL ... Difflam Forte Anti-Inflammatory Throat Spray …
Primidone
Primidone is an anticonvulsant used to treat essential tremor as well as grand mal, psychomotor, and focal epileptic seizures. Primidone was developed by J Yule Bogue and H C Carrington in 1949. Primidone was granted FDA Approval on 8 March 1954.
Approved
Vet approved
Matched Synonyms: … 5-Phenyl-5-ethyl-Hexahydropyrimidine-4,6-dione …
Matched Iupac: … 5-ethyl-5-phenyl-1,3-diazinane-4,6-dione …
Matched Description: … [L11112] Primidone was developed by J Yule Bogue and H C Carrington in 1949. ... Primidone is an anticonvulsant used to treat essential tremor as well as grand mal, psychomotor, and …
Matched Categories: … Barbiturates and Derivatives ... Hypnotics and Sedatives ... Phenobarbital and similars …
Matched Iupac: … 5-ethyl-5-phenyl-1,3-diazinane-4,6-dione …
Matched Description: … [L11112] Primidone was developed by J Yule Bogue and H C Carrington in 1949. ... Primidone is an anticonvulsant used to treat essential tremor as well as grand mal, psychomotor, and …
Matched Categories: … Barbiturates and Derivatives ... Hypnotics and Sedatives ... Phenobarbital and similars …
alpha-Naphthoflavone
Experimental
Matched Synonyms: … 2-phenyl-4H-naphtho(1,2-b)pyran-4-one …
Matched Iupac: … 2-phenyl-4H-benzo[h]chromen-4-one …
Matched Iupac: … 2-phenyl-4H-benzo[h]chromen-4-one …
Cresol
Cresol is a hydroxytoluene that can be extracted naturally from coal tar or made synthetically. Pure cresol is a mixture of ortho-, meta-, and para- isomers. Cresols are precursors or synthetic intermediates to various other compounds and materials, including plastics, pesticides, pharmaceuticals, disinfectants, and dyes. Ingestion of cresol induces toxicity...
Approved
Matched Description: … Cresols are precursors or synthetic intermediates to various other compounds and materials, including ... concentrations normally found in the environment however, cresols do not pose any significant risk for ... pain, and/or vomiting. …
Matched Categories: … Phenols …
Matched Products: … Formo Cresol ... Buckleys Formo Cresol …
Matched Categories: … Phenols …
Matched Products: … Formo Cresol ... Buckleys Formo Cresol …
2,6-dimethyl-4-[(E)-2-phenylethenyl]phenol
Experimental
Matched Name: … 2,6-dimethyl-4-[(E)-2-phenylethenyl]phenol …
Matched Iupac: … 2,6-dimethyl-4-[(1E)-2-phenylethenyl]phenol …
Matched Iupac: … 2,6-dimethyl-4-[(1E)-2-phenylethenyl]phenol …
AAV9/MFSD8
AAV9/MFSD8 is a gene therapy developed by Neurogene Inc. It is an adeno-associated virus serotype 9 (AAV9) vector with an engineered transgene encoding the human CLN7/MFSD8 gene for expression of active human major facilitator superfamily domain containing 8. It was investigated for the treatment of neuronal ceroid lipofuscinosis type 7.
Investigational
Matched Synonyms: … adeno-associated virus serotype 9 (AAV9) vector with engineered transgene encoding the human CLN7/MFSD8 gene for …
Matched Description: … It was investigated for the treatment of neuronal ceroid lipofuscinosis type 7. ... adeno-associated virus serotype 9 (AAV9) vector with an engineered transgene encoding the human CLN7/MFSD8 gene for …
Matched Description: … It was investigated for the treatment of neuronal ceroid lipofuscinosis type 7. ... adeno-associated virus serotype 9 (AAV9) vector with an engineered transgene encoding the human CLN7/MFSD8 gene for …
Anileridine
Anileridine is a synthetic opioid and strong analgesic medication. It is a narcotic pain reliever used to treat moderate to severe pain. Narcotic analgesics act in the central nervous system (CNS) to relieve pain. Some of their side effects are also caused by actions in the CNS.
Approved
Illicit
Matched Synonyms: … N-(β-(p-aminophenyl)ethyl)-4-phenyl-4-carbethoxypiperidine ... ethyl 1-(2-(4-aminophenyl)ethyl)-4-phenyl-4-piperidinecarboxylate ... 1-[2-(4-aminophenyl)ethyl]-4-phenyl-4-piperidinecarboxlic acid ethyl ester …
Matched Description: … Anileridine is a synthetic opioid and strong analgesic medication. …
Matched Description: … Anileridine is a synthetic opioid and strong analgesic medication. …
Polatuzumab vedotin
Polatuzumab vedotin is a CD79b-directed antibody-drug conjugate that delivers monomethyl auristatin E (MMAE), an anti-mitotic agent, to cancer cells. The drug consists of three components - a humanized immunoglobulin G1 (IgG1) monoclonal antibody specific for human CD79b (polatuzumab), MMAE, and protease-cleavable linker called maleimidocaproyl-valine-citrulline-p-aminobenzyloxycarbonyl (mc-vc-PAB) that covalently attaches MMAE to...
Approved
Investigational
Matched Description: … [L6658]
Polatuzumab vedotin was granted accelerated FDA approval on June 10, 2019 [A254936] and was ... human CD79b (polatuzumab), MMAE, and protease-cleavable linker called maleimidocaproyl-valine-citrulline-p-aminobenzyloxycarbonyl ... drug consists of three components - a humanized immunoglobulin G1 (IgG1) monoclonal antibody specific for …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES …
Matched Products: … POLIVY POWDER FOR CONCENTRATE FOR SOLUTION FOR INFUSION 140MG ... POLIVY POWDER FOR CONCENTRATE FOR SOLUTION FOR INFUSION 30MG ... POLIVY 140mg Powder For Concentrate For Solution For Infusion …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES …
Matched Products: … POLIVY POWDER FOR CONCENTRATE FOR SOLUTION FOR INFUSION 140MG ... POLIVY POWDER FOR CONCENTRATE FOR SOLUTION FOR INFUSION 30MG ... POLIVY 140mg Powder For Concentrate For Solution For Infusion …
Combretastatin A4
Experimental
Investigational
Matched Synonyms: … PHENOL, 2-METHOXY-5-(2-(3,4,5-TRIMETHOXYPHENYL)ETHENYL)-, (Z)- …
Matched Iupac: … 2-methoxy-5-[(Z)-2-(3,4,5-trimethoxyphenyl)ethenyl]phenol …
Matched Iupac: … 2-methoxy-5-[(Z)-2-(3,4,5-trimethoxyphenyl)ethenyl]phenol …
(3,4-Dihydroxy-Phenyl)-Triphenyl-Arsonium
Experimental
Matched Name: … (3,4-Dihydroxy-Phenyl)-Triphenyl-Arsonium …
N-[4-(benzyloxy)phenyl]glycinamide
Experimental
Matched Name: … N-[4-(benzyloxy)phenyl]glycinamide …
Matched Iupac: … 2-amino-N-[4-(benzyloxy)phenyl]acetamide …
Matched Iupac: … 2-amino-N-[4-(benzyloxy)phenyl]acetamide …
Alprazolam
Alprazolam is a triazolobenzodiazepine indicated for the treatment of anxiety and panic disorders.[L34783, L34788] It is mainly metabolized by CYP3As and so is contraindicated with CYP3A inhibitors like ketoconazole and itraconazole.[L34783, L34788] Benzodiazepine treatment should be stopped gradually by tapering down a patient's dose to avoid withdrawal symptoms. Alprazolam's adverse...
Approved
Illicit
Investigational
Matched Synonyms: … 8-Chloro-1-methyl-6-phenyl-4H-s-triazolo(4,3-a)(1,4)benzodiazepine …
Matched Iupac: … 12-chloro-3-methyl-9-phenyl-2,4,5,8-tetraazatricyclo[8.4.0.0^{2,6}]tetradeca-1(10),3,5,8,11,13-hexaene …
Matched Description: … Alprazolam is a triazolobenzodiazepine indicated for the treatment of anxiety and panic disorders. ... ketoconazole and itraconazole. ... [L34783, L34788] It is mainly metabolized by CYP3As and so is contraindicated with CYP3A inhibitors like …
Matched Categories: … Hypnotics and Sedatives ... Benzodiazepines and benzodiazepine derivatives …
Matched Iupac: … 12-chloro-3-methyl-9-phenyl-2,4,5,8-tetraazatricyclo[8.4.0.0^{2,6}]tetradeca-1(10),3,5,8,11,13-hexaene …
Matched Description: … Alprazolam is a triazolobenzodiazepine indicated for the treatment of anxiety and panic disorders. ... ketoconazole and itraconazole. ... [L34783, L34788] It is mainly metabolized by CYP3As and so is contraindicated with CYP3A inhibitors like …
Matched Categories: … Hypnotics and Sedatives ... Benzodiazepines and benzodiazepine derivatives …
AMG-208
AMG-208 has been used in trials studying the treatment of Cancer, Tumors, Oncology, Prostate Cancer, and Oncology Patients, among others.
Investigational
Matched Synonyms: … 7-methoxy-4-[(6-phenyl[1,2,4]triazolo[4,3-b]pyridazin-3-yl)methoxy]quinoline …
Matched Iupac: … 7-methoxy-4-({6-phenyl-[1,2,4]triazolo[4,3-b]pyridazin-3-yl}methoxy)quinoline …
Matched Description: … AMG-208 has been used in trials studying the treatment of Cancer, Tumors, Oncology, Prostate Cancer, and …
Matched Iupac: … 7-methoxy-4-({6-phenyl-[1,2,4]triazolo[4,3-b]pyridazin-3-yl}methoxy)quinoline …
Matched Description: … AMG-208 has been used in trials studying the treatment of Cancer, Tumors, Oncology, Prostate Cancer, and …
Bezuclastinib
Investigational
Matched Synonyms: … 3,4-dimethyl-n-(2-phenyl-1h-pyrrolo(2,3-b)pyridin-5-yl)-1h-pyrazole-5-carboxamide ... 3,4-dimethyl-N-(2-phenyl-1H-pyrrolo[2,3-b]pyridin-5-yl)-1H-pyrazole-5- carboxamide …
Matched Iupac: … 4,5-dimethyl-N-{2-phenyl-1H-pyrrolo[2,3-b]pyridin-5-yl}-1H-pyrazole-3-carboxamide …
Matched Iupac: … 4,5-dimethyl-N-{2-phenyl-1H-pyrrolo[2,3-b]pyridin-5-yl}-1H-pyrazole-3-carboxamide …
Vepdegestrant
Vepdegestrant is under investigation in clinical trial NCT05909397 (A Study of ARV-471 (PF-07850327) Plus Palbociclib Versus Letrozole Plus Palbociclib in Participants With Estrogen Receptor Positive, Human Epidermal Growth Factor Negative Advanced Breast Cancer).
Investigational
Matched Synonyms: … 1-naphthalenyl)phenyl)-4-piperidinyl)methyl)-1-piperazinyl)-2h-isoindol-2-yl)-, (3s)- ... 2,6-piperidinedione, 3-(1,3-dihydro-1-oxo-5-(4-((1-(4-((1r,2s)-1,2,3,4-tetrahydro-6-hydroxy-2-phenyl- …
10-formyl-5,8,10-trideazafolic acid
Experimental
Matched Name: … 10-formyl-5,8,10-trideazafolic acid …
Matched Iupac: … (2S)-2-({4-[(1S)-2-(2-amino-4-oxo-1,4-dihydroquinazolin-6-yl)-1-carboxyethyl]phenyl}formamido)pentanedioic …
Matched Iupac: … (2S)-2-({4-[(1S)-2-(2-amino-4-oxo-1,4-dihydroquinazolin-6-yl)-1-carboxyethyl]phenyl}formamido)pentanedioic …
Idelalisib
Idelalisib is a phosphoinositide 3-kinase inhibitor indicated in the treatment of chronic lymphocytic leukemia (CLL), relapsed follicular B-cell non-Hodgkin lymphoma (FL), and relapsed small lymphocytic lymphoma (SLL). For the treatment of relapsed CLL, it is currently indicated as a second-line agent in combination with rituximab in patients for whom rituximab...
Approved
Matched Synonyms: … 5-Fluoro-3-phenyl-2-((S)-1-(9H-purin-6-ylamino)-propyl)-3H-quinazolin-4-one ... 5-fluoro-3-phenyl-2-[(1S)-1-(3H-purin-6-ylamino)propyl]quinazolin-4(3H)-one …
Matched Iupac: … 5-fluoro-3-phenyl-2-[(1S)-1-[(9H-purin-6-yl)amino]propyl]-3,4-dihydroquinazolin-4-one …
Matched Description: … (white blood cells) and is important for the function of T cells, B cell, mast cells and neutrophils ... rituximab in patients for whom rituximab alone would be considered appropriate therapy due to other ... For the treatment of relapsed CLL, it is currently indicated as a second-line agent in combination with …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Iupac: … 5-fluoro-3-phenyl-2-[(1S)-1-[(9H-purin-6-yl)amino]propyl]-3,4-dihydroquinazolin-4-one …
Matched Description: … (white blood cells) and is important for the function of T cells, B cell, mast cells and neutrophils ... rituximab in patients for whom rituximab alone would be considered appropriate therapy due to other ... For the treatment of relapsed CLL, it is currently indicated as a second-line agent in combination with …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
3-(4-(8-Fluoroquinoline) imidazole(1,2-a)pyridine-7-(1-phenyl-4-(1-(4-methyl piperazine)
Investigational
Matched Synonyms: … 3-(4-(8-fluoroquinoline)imidazole(1,2-a)pyridine-7-(1-phenyl-4-(1-(4-methyl piperazine) ... Quinoline, 8-fluoro-4-(7-(4-(4-methyl-1-piperazinyl)phenyl)imidazo(1,2-a)pyridin-3-yl)- …
Matched Name: … 3-(4-(8-Fluoroquinoline) imidazole(1,2-a)pyridine-7-(1-phenyl-4-(1-(4-methyl piperazine) …
Matched Iupac: … 8-fluoro-4-{7-[4-(4-methylpiperazin-1-yl)phenyl]imidazo[1,2-a]pyridin-3-yl}quinoline …
Matched Name: … 3-(4-(8-Fluoroquinoline) imidazole(1,2-a)pyridine-7-(1-phenyl-4-(1-(4-methyl piperazine) …
Matched Iupac: … 8-fluoro-4-{7-[4-(4-methylpiperazin-1-yl)phenyl]imidazo[1,2-a]pyridin-3-yl}quinoline …
Displaying drugs 701 - 725 of 1964 in total