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Displaying drugs 7251 - 7275 of 7791 in total
Tagatose is a functional sweetener. It is a naturally occurring monosaccharide, specifically a hexose. It is commonly found in dairy with a similar texture and sweetened capacity to sucrose but with only a third of the calories. It is approved as a food additive as a low calorie sweetener. Additionally,...
Investigational
Matched Synonyms: … (3S,4S,5R)-1,3,4,5,6-pentahydroxyhexan-2-one ... D-lyxo-hex-2-ulose …
Matched Iupac: … (3S,4S,5R)-1,3,4,5,6-pentahydroxyhexan-2-one …
Matched Description: … It is commonly found in dairy with a similar texture and sweetened capacity to sucrose but with only ... Additionally, it is under investigation by Spherix for the treatment of obesity and type II diabetes. ... It is approved as a food additive as a low calorie sweetener. …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Sibutramine (trade name Meridia in the USA, Reductil in Europe and other countries), usually as sibutramide hydrochloride monohydrate, is an orally administered agent for the treatment of obesity. It is a centrally acting stimulant chemically related to amphetamines thus it is classified as a Schedule IV controlled substance in the...
Approved
Illicit
Investigational
Withdrawn
Matched Iupac: … {1-[1-(4-chlorophenyl)cyclobutyl]-3-methylbutyl}dimethylamine …
Matched Description: … Sibutramine (trade name Meridia in the USA, Reductil in Europe and other countries), usually as sibutramide ... increases the risk of heart attack and stroke in patients with a history of heart disease. ... In October 2010, Sibutramine was withdrawn from Canadian and U.S. markets due to concerns that the drug …
Matched Salts cas: … 125494-59-9 …
Matched Categories: … Alimentary Tract and Metabolism ... Serotonin and Noradrenaline Reuptake Inhibitors ... Norepinephrine, Serotonin, and Dopamine Reuptake Inhibitor Anorectic ... Cytochrome P-450 Substrates ... Cytochrome P-450 CYP3A Substrates …
Matched Products: … OBESTOPPOR 5 MG CAPSULAS ... SEROTRAMIN CAPSULAS 20 MG. ... MESURA-ABL 10 MG CAPSULAS …
Experimental
Matched Synonyms: … N6-(3-methylbut-2-enyl)adenine ... N(6)-(delta(2)-Isopentenyl)adenine …
Matched Iupac: … N-(3-methylbut-2-en-1-yl)-9H-purin-6-amine …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides ... Vitamin B Complex ... Heterocyclic Compounds, 2-Ring …
INM004, a Neutralizing Equine Anti-Stx Hyperimmune Immunoglobulin F(Ab')2 Fragment, is currently being investigated to treat Shiga-toxin producing bacterial infection relating to the prevention of hemolytic uremic syndrome.
Investigational
Matched Synonyms: … Anti-Shiga toxin hyperimmune equine immunoglobulin F(ab')2 fragment ... Neutralizing equine anti-Stx hyperimmune immunoglobulin F(ab')2 fragment …
Matched Description: … INM004, a Neutralizing Equine Anti-Stx Hyperimmune Immunoglobulin F(Ab')2 Fragment, is currently being …
Ustekinumab is a human immunoglobulin (Ig) G1 kappa monoclonal antibody directed against interleukin(IL)-12 and IL-23, which are cytokines that are involved in immune and inflammatory responses. It was generated via recombinant human IL-12 immunization of human Ig (hu-Ig) transgenic mice. It is a targeted biologic disease-modifying anti-rheumatic drug (bDMARDs) that...
Approved
Investigational
Matched Description: … the interleukin (IL)-12 and IL-23 cytokines. ... IL)-12 and IL-23, which are cytokines that are involved in immune and inflammatory responses. ... management of various inflammatory conditions that involve the activation of IL-12 and IL-23 signalling …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Skin and Mucous Membrane Agents ... Antineoplastic and Immunomodulating Agents ... Interleukin-12 Antagonist ... Interleukin-23 Antagonist …
Matched Products: … STELARA 130 MG / 26 ML İNFÜZYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN KONSANTRE ... STELARA® 45 MG/0.5 ML ... STELARA 45 MG ENJEKSİYONLUK ÇÖZELTİ …
Experimental
Matched Name: … (5S,8R,9S,10S,13R,14S,17S)-13-{2-[(3,5-DIFLUOROBENZYL)OXY]ETHYL}-17-HYDROXY-10-METHYLHEXADECAHYDRO-3H-CYCLOPENTA ... [A]PHENANTHREN-3-ONE …
Matched Iupac: … -1H-cyclopenta[a]phenanthren-7-one ... (1S,3aS,3bR,5aS,9aS,9bS,11aR)-11a-{2-[(3,5-difluorophenyl)methoxy]ethyl}-1-hydroxy-9a-methyl-hexadecahydro …
Lepirudin is a recombinant hirudin formed by 65 amino acids that acts as a highly specific and direct thrombin inhibitor.[L41539,L41569] Natural hirudin is an endogenous anticoagulant found in Hirudo medicinalis leeches. Lepirudin is produced in yeast cells and is identical to natural hirudin except for the absence of sulfate on...
Approved
Withdrawn
Matched Synonyms: … Hirudin variant-1
Matched Description: … formed by heparin and platelet factor 4. ... position 1 (N-terminal end). ... Lepirudin is a recombinant hirudin formed by 65 amino acids that acts as a highly specific and direct …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Blood and Blood Forming Organs …
A pyrrolidinylmethyl tetracycline.
Approved
Matched Synonyms: … N-(1-Pyrrolidinylmethyl)-tetracycline …
Matched Iupac: … 1-yl)methyl]-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide ... (4S,4aS,5aS,6S,12aS)-4-(dimethylamino)-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-N-[(pyrrolidin- …
Matched Description: … A pyrrolidinylmethyl tetracycline. …
Experimental
Matched Synonyms: … 2,5-naphthalenediol ... 2,5-dihydroxynaphthalene ... 6-hydroxy-1-naphthol …
Matched Name: … 1,6-Naphthalenediol …
Matched Iupac: … naphthalene-1,6-diol …
Experimental
Matched Synonyms: … Thallium cation Tl-201 (1+) ... Thallous ion Tl-201 ... Thallium cation Tl-201
Matched Name: … Thallous cation Tl-201
Alcohol use disorder is responsible for a large worldwide burden of morbidity, premature mortality, and economic consequences resulting from accidents, violence, incarceration, decreased productivity, and increased healthcare spending. Acamprosate, also known by the brand name Campral, is a drug used for the maintenance of alcohol abstinence. It is a structural...
Approved
Investigational
Matched Synonyms: … 3-Acetamido-1-propanesulfonic acid …
Matched Iupac: … 3-acetamidopropane-1-sulfonic acid …
Matched Description: … It was first approved by the FDA in 2004 and initially marketed by Forest Laboratories.[L31783] ... Alcohol use disorder is responsible for a large worldwide burden of morbidity, premature mortality, and ... economic consequences resulting from accidents, violence, incarceration, decreased productivity, and
Matched Salts cas: … 77337-73-6 …
Irosustat has been investigated for the treatment of Metastatic Breast Cancer and Locally Advanced Breast Cancer.
Investigational
Matched Synonyms: … 6-Oxo-8,9,10,11-Tetrahydro-7h-Cyclohepta[C][1]Benzopyran-3-O-Sulfamate …
Matched Iupac: … 6-oxo-6H,7H,8H,9H,10H,11H-cyclohepta[c]chromen-3-yl sulfamate …
Matched Description: … Irosustat has been investigated for the treatment of Metastatic Breast Cancer and Locally Advanced Breast …
Carbazochrome is a hemostatic agent that promotes clotting, preventing blood loss from open wounds. It is an oxidation product of adrenaline which enhances the microcirculatory tone . In the future this may prevent excessive blood flow during surgical operations and the treatment of hemorrhoids, but research on effectiveness and severity...
Experimental
Withdrawn
Matched International brands: … Su Bo Te ... Adcar AC
Matched Synonyms: … 3-Hydroxy-1-methyl-5,6-inodlindionsemicarbazon …
Matched Iupac: … {[(5Z)-3-hydroxy-1-methyl-6-oxo-2,3,5,6-tetrahydro-1H-indol-5-ylidene]amino}urea …
Matched Description: … , but research on effectiveness and severity of side effects remains inconclusive. ... mixture with [DB13124], and this combination therapy demonstrated efficacy and safe tolerability either ... It is not FDA-approved but is available as tablets or IM/SC injections in the treatment of hemorrhages …
Matched Categories: … Blood and Blood Forming Organs ... Heterocyclic Compounds, 2-Ring …
Investigational
Matched Synonyms: … Ethyl (+)-(2s,3s)-2,3-epoxy-n-((s)-1-(isopentylcarbamoyl)-3-methylbutyl)succinamate …
Matched Iupac: … ethyl (2S,3S)-3-{[(1S)-3-methyl-1-[(3-methylbutyl)carbamoyl]butyl]carbamoyl}oxirane-2-carboxylate …
Matched Categories: … Amino Acids, Peptides, and Proteins …
A recombinant DNA-derived cytotoxic protein composed of the amino acid sequences for diphtheria toxin fragments A and B (Met 1-Thr 387)-His followed by the sequences for interleukin-2 (IL-2; Ala 1-Thr 133). It is produced in an E. coli expression system.
Approved
Investigational
Matched Synonyms: … Interleukin-2/diptheria toxin fusion protein …
Matched Description: … fragments A and B (Met 1-Thr 387)-His followed by the sequences for interleukin-2 (IL-2; Ala 1-Thr 133 ... It is produced in an E. coli expression system. ... A recombinant DNA-derived cytotoxic protein composed of the amino acid sequences for diphtheria toxin …
Matched Categories: … Enzymes and Coenzymes ... Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Intercellular Signaling Peptides and Proteins ... ADP Ribose Transferases …
Sevoflurane is an ether inhalation anesthetic agent used to induce and maintain general anesthesia. It is a volatile, non-flammable compound with a low solubility profile and blood/gas partition coefficient. Sevoflurane was patented in 1972, was approved for clinical use in Japan in 1990, and approved by the FDA in 1996....
Approved
Vet approved
Matched Synonyms: … 1,1,1,3,3,3-Hexafluoro-2-(fluoromethoxy)propane …
Matched Iupac: … 1,1,1,3,3,3-hexafluoro-2-(fluoromethoxy)propane …
Matched Description: … [A249910] Therefore, it can be used for inhalational induction in adults and children for a wide variety ... by the FDA in 1996. ... The hemodynamic and respiratory depressive effects of sevoflurane are well tolerated, and most patients …
Matched Categories: … Cytochrome P-450 Substrates ... Cytochrome P-450 CYP2A6 Substrates ... Cytochrome P-450 CYP2B6 Substrates ... Cytochrome P-450 CYP3A Substrates ... Cytochrome P-450 CYP2E1 Substrates …
Matched Products: … Sevorane AF ... SOJOURN % 100 INHALASYON COZELTISİ 250 ML ... SEVORANE %100 İNHALASYON ÇÖZELTİSİ, 250 ML …
Experimental
Matched Synonyms: … 2-hydroxy-1,2,3-propanetricarboxylic acid silver salt …
Matched Iupac: … trisilver(1+) ion 2-hydroxypropane-1,2,3-tricarboxylate …
Matched Mixtures name: … All-Natural Pen Spray …
Experimental
Matched Name: … Uridine-5'-Diphosphate-N-Acetylmuramoyl-L-Alanine …
Matched Iupac: … (2S)-2-[(2R)-2-{[(2R,3R,4R,5S,6R)-2-({[({[(2R,3S,4R,5R)-5-(2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl ... -6-(hydroxymethyl)oxan-4-yl]oxy}propanamido]propanoic acid ... )-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy](hydroxy)phosphoryl}oxy)-3-acetamido-5-hydroxy …
Experimental
Matched Name: … 6,4'-Dihydroxy-3-Methyl-3',5'-Dibromoflavone …
Matched Iupac: … 2-(3,5-dibromo-4-hydroxyphenyl)-6-hydroxy-3-methyl-4H-chromen-4-one …
Experimental
Matched Name: … 5-monophosphate-9-beta-D-ribofuranosyl xanthine …
Matched Iupac: … 9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-[(phosphonooxy)methyl]oxolan-2-yl]-2,6-dioxo-2,3,6,7-tetrahydro-1H-9lambda5 …
Experimental
Matched Name: … N(5)-[(hydroxyamino)(imino)methyl]-L-ornithine …
Matched Iupac: … (2S)-2-amino-5-(N'-hydroxycarbamimidamido)pentanoic acid …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Experimental
Matched Name: … 5-Alpha-Androstane-3-Beta,17beta-Diol …
Matched Iupac: … (1S,3aS,3bR,5aS,7S,9aS,9bS,11aS)-9a,11a-dimethyl-hexadecahydro-1H-cyclopenta[a]phenanthrene-1,7-diol …
Experimental
Matched Name: … 3'-Deoxy 3'-Amino Adenosine-5'-Diphosphate …
Matched Iupac: … [({[(2S,3S,4R,5R)-3-amino-5-(6-amino-9H-purin-9-yl)-4-hydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl) …
Experimental
Matched Name: … 6-CYCLOHEXYLMETHYLOXY-5-NITROSO-PYRIMIDINE-2,4-DIAMINE …
Matched Iupac: … 6-(cyclohexylmethoxy)-5-nitrosopyrimidine-2,4-diamine …
Gadoteridol is a macrocyclic nonionic gadolinium that provides contrast enhancement of the brain, spine, and surrounding tissues, resulting in improved visualization (compared with unenhanced MRI) of lesions with abnormal vascularity or those thought to disrupt the normal blood-brain barrier.[A263076,A263081,L49871] It was 1 of the 3 macrocyclic gadolinium-based contrast agents (GBCAs)...
Approved
Investigational
Matched Synonyms: … gadolinium 2,2',2''-[10-(2-hydroxypropyl)-1,4,7,10-tetraazacyclododecane-1,4,7-triyl]triacetate …
Matched Iupac: … gadolinium(3+) 2-[4,7-bis(carboxylatomethyl)-10-(2-hydroxypropyl)-1,4,7,10-tetraazacyclododecan-1-yl] …
Matched Description: … , and surrounding tissues, resulting in improved visualization (compared with unenhanced MRI) of lesions ... was mandated by the EMA to replace linear gadolinium-based contrast agents due to concerns about retained ... [A263076] Initially approved by the FDA in 1992, gadoteridol received additional approval in 2020 …
Matched Categories: … Drugs that are Mainly Renally Excreted ... Compounds used in a research, industrial, or household setting …
Displaying drugs 7251 - 7275 of 7791 in total