Displaying drugs 7351 - 7375 of 8349 in total
Vesencumab
Vesencumab is under investigation in clinical trial NCT00747734 (A Study of MNRP1685A in Patients With Locally Advanced or Metastatic Solid Tumors).
Investigational
Matched Description: … Vesencumab is under investigation in clinical trial NCT00747734 (A Study of MNRP1685A in Patients With …
Yersinia pestis 195/p antigen (formaldehyde inactivated)
Yersinia pestis 195/p antigen (formaldehyde inactivated) is under investigation in clinical trial NCT02596308 (Immunogenicity and Safety of Subunit Plague Vaccine).
Investigational
Matched Description: … formaldehyde inactivated) is under investigation in clinical trial NCT02596308 (Immunogenicity and Safety of …
Recombinant human plasma gelsolin
Plasma gelsolin (pGSN) is a protein found in the blood of healthy individuals which scavenges compounds left over from damaged tissues.
Investigational
Matched Description: … Plasma gelsolin (pGSN) is a protein found in the blood of healthy individuals which scavenges compounds …
Apinocaltamide
Apinocaltamide is under investigation in clinical trial NCT03239691 (A Study to Evaluate the Effect of ACT-709478 in Photosensitive Epilepsy Patients).
Investigational
Matched Description: … Apinocaltamide is under investigation in clinical trial NCT03239691 (A Study to Evaluate the Effect of …
Abelacimab
Abelacimab is under investigation in clinical trial NCT04755283 (Safety and Tolerability of Abelacimab (MAA868) vs. Rivaroxaban in Patients With Atrial Fibrillation).
Investigational
Matched Description: … Abelacimab is under investigation in clinical trial NCT04755283 (Safety and Tolerability of Abelacimab …
U-0126
U-0126 is a direct inhibitor of the mitogen-activated protein-kinase kinase family members, MEK-1 and MEK-2.
Investigational
Matched Description: … U-0126 is a direct inhibitor of the mitogen-activated protein-kinase kinase family members, MEK-1 and …
Emprumapimod
Emprumapimod is a potent, orally active and selective inhibitor of p38α mitogen-activated kinase inhibitor. It was investigated for dilated cardiomyopathy.
Investigational
Matched Description: … Emprumapimod is a potent, orally active and selective inhibitor of p38α mitogen-activated kinase inhibitor …
Dalcinonacog alfa
Dalcinonacog alfa is a recombinant human factor IX (FIX) variant. It is being investigated for the treatment of hemophilia B.
Investigational
Matched Description: … It is being investigated for the treatment of hemophilia B.[A259058] …
SPL23-2
SPL23-2 is an antisense oligonucleotide (ASO) targeting the W1282X nonsense mutation associated with a severe form of cystic fibrosis.
Investigational
Matched Description: … antisense oligonucleotide (ASO) targeting the W1282X nonsense mutation associated with a severe form of …
TTX-MC138
TTX-MC138 is an antisense oligonucleotide targeting miR-10b. It is under investigation for the treatment of various metastatic cancers.
Investigational
Matched Description: … [L48335] It is under investigation for the treatment of various metastatic cancers. …
Xeligekimab
Xeligekimab is under investigation in clinical trial NCT06028490 (A Study of Il4rα Monoclonal Antibody in Patients With Uncontrolled Seasonal Allergic Rhinitis.).
Investigational
Matched Description: … Xeligekimab is under investigation in clinical trial NCT06028490 (A Study of Il4rα Monoclonal Antibody …
Rulonilimab
Rulonilimab is under investigation in clinical trial NCT05408221 (The Efficacy and Safety of Rulonilimab in Combination With Lenvatinib in Hepatocellular Carcinoma).
Investigational
Matched Description: … Rulonilimab is under investigation in clinical trial NCT05408221 (The Efficacy and Safety of Rulonilimab …
Barzolvolimab
Barzolvolimab is under investigation in clinical trial NCT06455202 (A Phase 3 Study of Barzolvolimab in Participants With Chronic Spontaneous Urticaria (CSU)).
Investigational
Matched Description: … Barzolvolimab is under investigation in clinical trial NCT06455202 (A Phase 3 Study of Barzolvolimab …
Pirmitegravir
Pirmitegravir is under investigation in clinical trial NCT05869643 (A Clinical Trial of STP0404 in Treatment-naïve Adults With HIV-1 Infection).
Investigational
Matched Description: … Pirmitegravir is under investigation in clinical trial NCT05869643 (A Clinical Trial of STP0404 in Treatment-naïve …
Veligrotug
Veligrotug is under investigation in clinical trial NCT00791544 (Dose Finding Study of AVE1642 in Patients With Advanced or Metastatic Liver Carcinoma).
Investigational
Matched Description: … Veligrotug is under investigation in clinical trial NCT00791544 (Dose Finding Study of AVE1642 in Patients …
Fepixnebart
Fepixnebart is under investigation in clinical trial NCT04456686 (Chronic Pain Master Protocol (CPMP): A Study of LY3016859 in Participants With Osteoarthritis).
Investigational
Matched Description: … is under investigation in clinical trial NCT04456686 (Chronic Pain Master Protocol (CPMP): A Study of …
Kisspeptin
Kisspeptin is under investigation in clinical trial NCT03315325 (Age-dependent Changes in the Responsiveness of Hypothalamic Pituitary Gonadal Axis in Men).
Investigational
Matched Description: … Kisspeptin is under investigation in clinical trial NCT03315325 (Age-dependent Changes in the Responsiveness of …
EA-230
EA-230 is under investigation in clinical trial NCT03145220 (Immunomodulation of EA-230 Following On-pump Coronary Artery Bypass Grafting (CABG)).
Investigational
Matched Description: … EA-230 is under investigation in clinical trial NCT03145220 (Immunomodulation of EA-230 Following On-pump …
Ectoine
Ectoine is under investigation in clinical trial NCT03186755 (Clinical Evaluation of Hylo-dual Versus Patanol in Children With Seasonal Allergic Conjunctivitis).
Investigational
Matched Description: … Ectoine is under investigation in clinical trial NCT03186755 (Clinical Evaluation of Hylo-dual Versus …
ONO-5334
ONO-5334 is under investigation in clinical trial NCT00532337 (Controlled Study of ONO-5334 in Postmenopausal Women With Osteopenia or Osteoporosis).
Investigational
Matched Description: … ONO-5334 is under investigation in clinical trial NCT00532337 (Controlled Study of ONO-5334 in Postmenopausal …
Rifasutenizol
Rifasutenizol is under investigation in clinical trial NCT05857163 (Efficacy and Safety of Rifasutenizol (TNP 2198) in Participants With H. Pylori Infection).
Investigational
Matched Description: … Rifasutenizol is under investigation in clinical trial NCT05857163 (Efficacy and Safety of Rifasutenizol …
Renadirsen
Renadirsen is under investigation in clinical trial NCT04433234 (Long-term, Extension Study of Ds-5141b in Patients With Duchenne Muscular Dystrophy).
Investigational
Matched Description: … Renadirsen is under investigation in clinical trial NCT04433234 (Long-term, Extension Study of Ds-5141b …
COVID19 s-vax loaded autologous dendritic cell vaccine
Dendritic cells (DCs) can be derived and differentiated from peripheral blood mononuclear cells in the presence of specific cytokines and growth factors. These cells are then loaded with antigens produced by a virus or tumor cell and administered as a vaccine.
Dendritic Cells (DCs) are showing potential as natural adjuvants...
Investigational
Matched Description: … and immunogenicity of the vaccine. ... cells (DCs) can be derived and differentiated from peripheral blood mononuclear cells in the presence of ... As of May 2020, the company is pursuing a human clinical trial (ChiCTR2000033003) to test the safety …
SARS-CoV-2 Sclamp
The University of Queensland (UQ), in partnership with The Coalition for Epidemic Preparedeness Inovations (CEPI) and CSL has developed a COVID-19 candidate, SARS-CoV-2 Sclamp. The vaccine was developed using UQ’s rapid response ‘molecular clamp’ vaccine platform that locks surface proteins in a configuration that allows more robust immune responses, in...
Investigational
Matched Description: … The University of Queensland (UQ), in partnership with The Coalition for Epidemic Preparedeness Inovations ... Preclinical trials showed the vaccine candidate produced high levels of neutralizing antibodies, and ... As of July 13, 2020, the candidate is being tested for safety and immunogenicity in Phase 1 clinical …
SPP 301
SPP301 (Avosentan) is a potent and highly selective ET[A] receptor blocker and is clinically investigated in diabetic nephropathy. This study was designed to evaluate whether avosentan influences the pharmacokinetics of steroid oral contraceptives.
Investigational
Matched Description: … This study was designed to evaluate whether avosentan influences the pharmacokinetics of steroid oral …
Displaying drugs 7351 - 7375 of 8349 in total