Displaying drugs 7376 - 7400 of 8039 in total
Ganaplacide
Ganaplacide is under investigation in clinical trial NCT03167242 (Efficacy and Safety of KAF156 in Combination With LUM-SDF in Adults and Children With Uncomplicated Plasmodium Falciparum Malaria).
Investigational
Matched Description: … Ganaplacide is under investigation in clinical trial NCT03167242 (Efficacy and Safety of KAF156 in Combination …
Efmitermant alfa
Efmitermant alfa, a locally-acting GDF/activin ligand trap, is under investigation in clinical trial NCT03124459 (Study of ACE-083 in Patients With Charcot-marie-tooth Disease).
Investigational
Matched Description: … locally-acting GDF/activin ligand trap, is under investigation in clinical trial NCT03124459 (Study of …
MRK-003
MRK-003 is a potent and selective γ-secretase inhibitor developed by Merck. It is the preclinical analog of MK-0752, a drug in clinical development.
Investigational
Matched Description: … It is the preclinical analog of [MK-0752], a drug in clinical development.[A252682] …
AEM-28
AEM-28 is a 28 amino acid mimetic of apolipoprotein E being investigated for lipid disorders, such as homozygous familial hypercholesterolemia. It possesses anti-inflammatory properties.
Investigational
Matched Description: … AEM-28 is a 28 amino acid mimetic of apolipoprotein E being investigated for lipid disorders, such as …
ALT-P1
ALT-P1 is a long-acting recombinant human growth hormone fused to an alpha1-antitrypsin variant. It is under investigation for the treatment of growth hormone deficiency.
Investigational
Matched Description: … It is under investigation for the treatment of growth hormone deficiency. …
Altropane
Boston Life Sciences (BLS) is developing Altropane as a potential radio-imaging agent to be used with single photon emission tomography (SPECT), for the early diagnosis of Parkinson's disease (PD) and attention deficit hyperactivity disorder (ADHD).
Investigational
Matched Description: … radio-imaging agent to be used with single photon emission tomography (SPECT), for the early diagnosis of …
P54
P54 reduces the inflammation associated with cancer/tumors, Crohn's disease, inflammatory bowel disease, osteoarthritis, and ulcerative colitis. It inhibits the induction of the enzyme NFkB, thereby inhibiting downstream inflammatory genes such as COX II and iNOS.
Investigational
Matched Description: … It inhibits the induction of the enzyme NFkB, thereby inhibiting downstream inflammatory genes such as …
Talnetant
Talnetant (SB-223,412) is a neurokinin 3 receptor antagonist developed by GlaxoSmithKline, which is being researched for several different functions, primarily for irritable bowel syndrome and as a potential antipsychotic drug for the treatment of schizophrenia.
Investigational
Matched Description: … functions, primarily for irritable bowel syndrome and as a potential antipsychotic drug for the treatment of …
Zalutumumab
Zalutumumab is a fully human IgG1 monoclonal antibody designed to bind with selectivity to the epidermal growth factor receptor (EGFR). Zalutumumab has been investigated for the treatment of Squamous Cell Cancer and Head and Neck Cancer.
Investigational
Matched Description: … Zalutumumab has been investigated for the treatment of Squamous Cell Cancer and Head and Neck Cancer. …
BMS-214662
BMS-214662 has been used in trials studying the treatment of Childhood Myelodysplastic Syndromes, Refractory Anemia With Excess Blasts, Recurrent Adult Acute Myeloid Leukemia, Relapsing Chronic Myelogenous Leukemia, and Adult Acute Promyelocytic Leukemia (M3), among others.
Investigational
Matched Description: … BMS-214662 has been used in trials studying the treatment of Childhood Myelodysplastic Syndromes, Refractory …
Efpeglenatide
Efpeglenatide is under investigation in clinical trial NCT03713684 (Efficacy and Safety of Efpeglenatide Versus Placebo in Patients With Type 2 Diabetes Mellitus Inadequately Controlled With Basal Insulin Alone or in Combination With Oral Antidiabetic Drug(s)).
Investigational
Matched Description: … Efpeglenatide is under investigation in clinical trial NCT03713684 (Efficacy and Safety of Efpeglenatide …
Perfluorodecalin
Perfluorodecalin is under investigation in clinical trial NCT03668665 (Influencing Wound Healing Through the Application of Hyaluronic Acid With Perfluorodecalin and Physalis Angulata Extract After Split Skin Removal From the Thigh - a Study in "Split Wound Design").
Investigational
Matched Description: … under investigation in clinical trial NCT03668665 (Influencing Wound Healing Through the Application of …
Dialyzable leukocyte extract
Transferon is comprised of several peptides mixed from human dialyzable leucocyte extracts and acts as an immunomodulator. It is thought to have widespread effects on the immune system, and effective in treating infections and immunological issues.
Investigational
Matched Description: … Transferon is comprised of several peptides mixed from human dialyzable leucocyte extracts and acts as …
ABBV-514
ABBV-514 is in development for the treatment of non-small cell lung cancer (NSCLC) and head and neck squamous cell carcinoma (HNSCC) as a single agent and in combination with a PD-1 inhibitor.
Investigational
Matched Description: … ABBV-514 is in development for the treatment of non-small cell lung cancer (NSCLC) and head and neck …
EGT-101
EGT-101 is an adeno-associated viral vector serotype 9 (AAV9) vector-based gene therapy consisting of the human sulfamidase (SGSH) transgene. Developed by Esteve Pharmaceuticals, it is being investigated for Sanfilippo syndrome type A.
Investigational
Matched Description: … EGT-101 is an adeno-associated viral vector serotype 9 (AAV9) vector-based gene therapy consisting of …
Droloxifene
Droloxifene, a derivative of the triphenylethylene drug tamoxifen, is a novel selective estrogen receptor modulator (SERM). Droloxifene also exhibits more rapid pharmacokinetics, reaching peak concentrations and being eliminated much more rapidly than tamoxifen. Its higher affinity to the estrogen receptor, higher anti-estrogenic to estrogenic ratio, more effective inhibition of cell...
Investigational
Matched Description: … Droloxifene, a derivative of the triphenylethylene drug tamoxifen, is a novel selective estrogen receptor ... affinity to the estrogen receptor, higher anti-estrogenic to estrogenic ratio, more effective inhibition of ... Droloxifene may also be a potentially useful agent for the treatment of postmenopausal osteoporosis because …
N-(4-carbamimidoylbenzyl)-1-(3-phenylpropanoyl)-L-prolinamide
N-(4-carbamimidoylbenzyl)-1-(3-phenylpropanoyl)-l-prolinamide is a solid. This compound belongs to the alpha amino acid amides. These are amide derivatives of alpha amino acids. This medication targets the protein prothrombin.
Experimental
Matched Description: … These are amide derivatives of alpha amino acids. This medication targets the protein prothrombin. …
Apomab
Apomab is under investigation in clinical trial NCT00851136 (A Study of PRO95780 Administered in Combination With the FOLFOX Regimen and Bevacizumab in Patients With Previously Untreated, Locally Advanced, Recurrent, and Metastatic Colorectal Cancer (APM4566g)).
Investigational
Matched Description: … Apomab is under investigation in clinical trial NCT00851136 (A Study of PRO95780 Administered in Combination …
Collagen-polyvinylpyrrolidone
Collagen-polyvinylpyrrolidone is a copolymer generated from a mixture of type I collagen and low-molecular-weight PVP that has undergone γ irradiation . It is characterized by antifibrotic, fibrolytic, and immunomodulatory properties .
Investigational
Matched Description: … Collagen-polyvinylpyrrolidone is a copolymer generated from a mixture of type I collagen and low-molecular-weight …
BT200
BT200 (Rondoraptivon pegol) is a PEGylated anti-von Willebrand factor (VWF) aptamer targeted against the VWF A1 domain. It is under investigation for the treatment of von Willebrand disease and hemophilia A.
Investigational
Matched Description: … [A261491] It is under investigation for the treatment of von Willebrand disease and hemophilia A. …
5-androstenedione
5-androstenedione is a prohormone of testosterone. In the United States, the Controlled Substance Act is inclusive to anabolic steroids and their precursors. Thus 5-androstenedione is a controlled substance, and its use in athletes is prohibited by The World Anti-Doping Agency. Apart from the positioning of a carbon-carbon double bond, its...
Experimental
Illicit
Matched Description: … 5-androstenedione is a prohormone of testosterone. ... Apart from the positioning of a carbon-carbon double bond, its structure is similar to [4-androstenedione …
Ularitide
Ularitide is a synthetic form of urodilatin, a naturally occurring human natriuretic peptide that is involved in regulating blood pressure and the excretion of water and sodium from the kidneys. Urodilatin is produced in the kidney and excreted into the urine, and thus exists in low levels naturally in the...
Investigational
Matched Description: … involved in regulating blood pressure and the excretion of water and sodium from the kidneys. ... Ularitide is a synthetic form of urodilatin, a naturally occurring human natriuretic peptide that is …
Synephrine
Synephrine, also referred to as, p-synephrine, is naturally occurring alkaloid. It is present in approved drug products as neo-synephrine, its m-substituted analog. p-synephrine and m-synephrine are known for their longer acting adrenergic effects compared to norepinephrine.
The similarity of naming between m-synephrine and the unsubstituted form, synephrine, is a source...
Experimental
Matched Description: … The similarity of naming between m-synephrine and the unsubstituted form, synephrine, is a source of …
Davunetide
Davunetide has been used in trials studying the treatment of Progressive Nonfluent Aphasia, Progressive Supranuclear Palsy, Predicted Tauopathies, Including, Corticobasal Degeneration Syndrome, and Frontotemporal Dementia With Parkinsonism Linked to Chromosome 17.
Davunetide is the first drug to improve memory performance by impacting the mechanisms that lead to physical damage in...
Investigational
Matched Description: … Davunetide has been used in trials studying the treatment of Progressive Nonfluent Aphasia, Progressive ... impacting the mechanisms that lead to physical damage in the brain caused by neurofibrillary tangles, one of …
Pictilisib
Pictilisib has been used in trials studying the treatment of Solid Cancers, Breast Cancer, Advanced Solid Tumours, Metastatic Breast Cancer, and Non-Hodgkin's Lymphoma, Solid Cancers, among others.
Investigational
Matched Description: … Pictilisib has been used in trials studying the treatment of Solid Cancers, Breast Cancer, Advanced Solid …
Displaying drugs 7376 - 7400 of 8039 in total