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Displaying drugs 51 - 75 of 293 in total
Tiludronic acid
Tiludronate, or (4-chlorophenyl)thio-methylene-1,1-bisphosphonate, is a first generation bisphosphonate similar to etidronic acid and clodronic acid.[A1923,A203111] These drugs were developed to mimic the action of pyrophosphate, a regulator of calcification and decalcification. Tiludronic acid was first described in the literature in 1988 as a potential treatment for Paget's disease of bone....
Approved
Investigational
Vet approved
Matched Description: … Tiludronate, or (4-chlorophenyl)thio-methylene-1,1-bisphosphonate, is a first generation bisphosphonate …
Aurothioglucose
Aurothioglucose, also known as gold thioglucose, was formerly used to treat rheumatoid arthritis.
Contemporary research on the effect of gold salts treatment began in 1935, primarily to reduce inflammation and to slow disease progression in patients with rheumatoid arthritis . The use of gold compounds has decreased since the 1980s...
Approved
Withdrawn
Lidocaine
Ever since its discovery and availability for sale and use in the late 1940s, lidocaine has become an exceptionally commonly used medication . In particular, lidocaine's principal mode of action in acting as a local anesthetic that numbs the sensations of tissues means the agent is indicated for facilitating local...
Approved
Vet approved
Matched Products: … Bio-Scriptives Lidum ... Bio-Scriptives Lidum Topical Analgesic ... Bio-Scriptives Lidum Hemorroidal (Anorectal) …
Mesoridazine
A phenothiazine antipsychotic with effects similar to chlorpromazine.
Approved
Investigational
Amifostine
A phosphorothioate proposed as a radiation-protective agent. It causes splenic vasodilation and may block autonomic ganglia.
Approved
Investigational
2-mercaptobenzothiazole
Approved
Experimental
Vet approved
Bithionol
Bithionol, formerly marketed as an active ingredient in various topical drug products, was shown to be a potent photosensitizer with the potential to cause serious skin disorders. Approvals of the NDA's for bithionol drug products were withdrawn on October 24, 1967 (see the Federal Register of October 31, 1967 (32...
Approved
Withdrawn
Lotilaner
Lotilaner is an ectoparasiticide that is a member of the isoxazoline family of compounds. Lotilaner has largely been used for veterinary uses as an antiparasitic agent to treat flea and tick infestations in animals.[A260746, L47556] Lotilaner consists of two enantiomers: the S-enantiomer is active in vivo, while the R-enantiomer is...
Approved
Vet approved
Zileuton
Leukotrienes are substances that induce numerous biological effects including augmentation of neutrophil and eosinophil migration, neutrophil and monocyte aggregation, leukocyte adhesion, increased capillary permeability, and smooth muscle contraction. These effects contribute to inflammation, edema, mucus secretion, and bronchoconstriction in the airways of asthmatic patients. Zileuton relieves such symptoms through its...
Approved
Investigational
Withdrawn
Cysteamine
Cystinosis is a rare disease caused by mutations in the CTNS gene that encodes for cystinosin, a protein responsible for transporting cystine out of the cell lysosome. A defect in cystinosin function is followed by cystine accumulation throughout the body, especially the eyes and kidneys. Several preparations of cysteamine exist...
Approved
Investigational
Promazine
A phenothiazine with actions similar to chlorpromazine but with less antipsychotic activity. It is primarily used in short-term treatment of disturbed behavior and as an antiemetic. It is currently not approved for use in the United States.
Approved
Vet approved
Suprofen
An ibuprofen-type anti-inflammatory analgesic and antipyretic. It inhibits prostaglandin synthesis and has been proposed as an anti-arthritic. It is no longer approved for use in the United States.
Approved
Withdrawn
4-Thio-beta-D-glucopyranose
Experimental
Matched Synonyms: … 4-Thio-β-D-glucopyranose ... 4-deoxy-4-Thio-beta-D-glucopyranose …
Matched Name: … 4-Thio-beta-D-glucopyranose …
Matched Name: … 4-Thio-beta-D-glucopyranose …
Adenosine 5'-[gamma-thio]triphosphate
A nucleoside triphosphate analogue that is ATP in which one of the oxygens attached to 3-phosphate group is replaced by sulfur.
Experimental
Matched Synonyms: … gamma-Thio-ATP ... Adenosine 5'-(3-thio)triphosphate ... Adenosine 5'-[γ-thio]triphosphate …
Matched Name: … Adenosine 5'-[gamma-thio]triphosphate …
Matched Name: … Adenosine 5'-[gamma-thio]triphosphate …
1-thio-beta-D-glucopyranose
Experimental
Matched Synonyms: … 1-thio-b-D-glucose ... 1-thio-β-D-glucose …
Matched Name: … 1-thio-beta-D-glucopyranose …
Matched Name: … 1-thio-beta-D-glucopyranose …
Methyl 4-thio-beta-D-glucopyranoside
Experimental
Matched Synonyms: … Methyl 4-thio-β-D-glucopyranoside …
Matched Name: … Methyl 4-thio-beta-D-glucopyranoside …
Matched Name: … Methyl 4-thio-beta-D-glucopyranoside …
4'-Thio-fac
4'-Thio-fac is under investigation in clinical trial NCT02661542 (Study of FF-10502-01 in Patients With Advanced Solid Tumors and Lymphomas).
Investigational
Matched Name: … 4'-Thio-fac …
Matched Description: … 4'-Thio-fac is under investigation in clinical trial NCT02661542 (Study of FF-10502-01 in Patients With …
Matched Description: … 4'-Thio-fac is under investigation in clinical trial NCT02661542 (Study of FF-10502-01 in Patients With …
PARA-NITROPHENYL 1-THIO-BETA-D-GLUCOPYRANOSIDE
Experimental
Matched Name: … PARA-NITROPHENYL 1-THIO-BETA-D-GLUCOPYRANOSIDE …
1-Deoxy-1-Thio-Heptaethylene Glycol
Experimental
Matched Name: … 1-Deoxy-1-Thio-Heptaethylene Glycol …
Displaying drugs 51 - 75 of 293 in total