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Displaying drugs 726 - 750 of 5758 in total
An antimitotic agent with immunosuppressive properties. Dexrazoxane, the (+)-enantiomorph of razoxane, provides cardioprotection against anthracycline toxicity. It appears to inhibit formation of a toxic iron-anthracycline complex. [PubChem] The Food and Drug Administration has designated dexrazoxane as an orphan drug for use in the prevention or reduction in the incidence and...
Approved
Withdrawn
Matched Synonyms: … (+)-1,2-Bis(3,5-dioxo-1-piperazinyl)propane ... 4-[(2S)-2-(3,5-dioxopiperazin-1-yl)propyl]piperazine-2,6-dione ... (+)-(S)-4,4'-Propylenedi-2,6-piperazinedione …
Matched Iupac: … 4-[(2S)-1-(3,5-dioxopiperazin-1-yl)propan-2-yl]piperazine-2,6-dione …
Matched Description: … [PubChem] The Food and Drug Administration has designated dexrazoxane as an orphan drug for use in the ... prevention or reduction in the incidence and severity of anthracycline-induced cardiomyopathy. ... It appears to inhibit formation of a toxic iron-anthracycline complex. …
Experimental
Matched Synonyms: … 3-[18-(2-Carboxyethyl)-7,12-diethyl-3,8,13,17,23-pentamethylporphyrin-21-id-2-yl]propanoic acid;copper
Matched Name: … N-Methylmesoporphyrin containing copper
Matched Iupac: … [16.2.1.1^{3,6}.1^{8,11}.1^{13,16}]tetracosa-1,3(24),4,6,8,10,12,14,16(22),17,19-undecaen-21-ide ... lambda1-copper(1+) 4,20-bis(2-carboxyethyl)-10,15-diethyl-5,9,14,19,23-pentamethyl-21,22,23,24-tetraazapentacyclo …
SGS-742 has been used in trials studying the treatment of Seizures and Metabolic Disease.
Investigational
Matched Synonyms: … 3-Aminopropyl-Butyl Phosphinic Acid ... (3-Aminopropyl)(n-butyl)phosphinic acid …
Matched Iupac: … (3-aminopropyl)(butyl)phosphinic acid …
Matched Description: … SGS-742 has been used in trials studying the treatment of Seizures and Metabolic Disease. …
Investigational
Matched Synonyms: … -methyl-2,6-dioxo-4-((4-(2-pyridinyloxy)phenyl)imino)-, (.alpha.s,4e)- ... 1,3,5-triazine-1(2h)-propanoic acid, 3-((4-chlorophenyl)methyl)tetrahydro-.alpha. …
Approved
Experimental
Matched Synonyms: … Sodium aurotiosulfate ... Gold sodium thiosulfate …
Matched Name: … Sodium aurotiosulfate …
Matched Iupac: … gold(1+) ion trisodium dihydrate disulfanidesulfonate …
Matched Categories: … Antiinflammatory and Antirheumatic Products ... sodium aurotiosulfate …
Experimental
Matched Synonyms: … gadolinium(3+) ion ... Gadolinium(3+) …
Matched Name: … Gadolinium cation (3+) …
Matched Iupac: … gadolinium(3+) ion
Ixazomib a second generation proteasome inhibitor (PI) and the first oral PI approved by the FDA in November 2015 for multiple myeloma treatment in combination with 2 other therapies (lenalidomide and dexamethasone) for patients who have received at least 1 prior therapy. It was found to have similar efficacy to...
Approved
Investigational
Matched Iupac: … [(1R)-1-{2-[(2,5-dichlorophenyl)formamido]acetamido}-3-methylbutyl]boronic acid …
Matched Description: … Ixazomib a second generation proteasome inhibitor (PI) and the first oral PI approved by the FDA in November ... ) in the control of myeloma growth and prevention of bone loss. ... 2015 for multiple myeloma treatment in combination with 2 other therapies (lenalidomide and dexamethasone …
Matched Salts cas: … 1239908-20-3
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Cytochrome P-450 Substrates ... Cytochrome P-450 CYP1A2 Substrates ... Cytochrome P-450 CYP2B6 Substrates …
Matched Products: … NİNLARO 4 MG KAPSÜL, 3 ADET ... NINLARO CAPSULE 4mg ... NINLARO (4 MG) CAPSULE …
Approved
Vet approved
Matched International brands: … Butyn
Matched Iupac: … 3-(dibutylamino)propyl 4-aminobenzoate …
Gallium chloride Ga-67 is the chloride salt of a gallium radioisotope which is typically complexed with sodium citrate to generate gallium citrate Ga 67, which can be used to image certain cancers and inflammatory lesions.
Approved
Matched Synonyms: … Gallium (67Ga) chloride ... Gallium chloride Ga 67 ... Gallium (Ga-67) chloride
Matched Name: … Gallium chloride Ga-67 …
Matched Iupac: … (67Ga)gallium(3+) trichloride …
Matched Description: … [sodium citrate] to generate [gallium citrate Ga 67], which can be used to image certain cancers and ... Gallium chloride Ga-67 is the chloride salt of a gallium radioisotope which is typically complexed with …
Mezigdomide is under investigation in clinical trial NCT05372354 (A Study to Evaluate Safety, Drug Levels and Effectiveness of CC-92480 (BMS-986348) in Combination With Other Treatments in Participants With Relapsed or Refractory Multiple Myeloma).
Investigational
Matched Synonyms: … Benzonitrile, 4-(4-((4-(((2-((3s)-2,6-dioxo-3-piperidinyl)-2,3-dihydro-1-oxo-1h-isoindol-4-yl)oxy)methyl ... 4-(4-((4-(((2-((3s)-2,6-dioxopiperidin-3-yl)-1-oxo-2,3-dihydro-1h-isoindol-4- yl)oxy)methyl)phenyl)methyl ... )phenyl)methyl)-1-piperazinyl)-3-fluoro- …
Matched Iupac: … 4-[4-({4-[({2-[(3S)-2,6-dioxopiperidin-3-yl]-1-oxo-2,3-dihydro-1H-isoindol-4-yl}oxy)methyl]phenyl}methyl ... )piperazin-1-yl]-3-fluorobenzonitrile …
Matched Description: … Mezigdomide is under investigation in clinical trial NCT05372354 (A Study to Evaluate Safety, Drug Levels and
Penbutolol is a drug in the beta-blocker class used to treat hypertension. Penbutolol binds both beta-1 and beta-2 adrenergic receptors, rendering it a non-selective beta-blocker. Penbutolol can act as a partial agonist at beta adrenergic receptors, since it is a sympathomimetric drug. Penbutolol also demonstrates high binding affinity to the...
Approved
Investigational
Matched Synonyms: … (2S)-1-(tert-butylamino)-3-(2-cyclopentylphenoxy)propan-2-ol …
Matched Iupac: … (2S)-1-(tert-butylamino)-3-(2-cyclopentylphenoxy)propan-2-ol …
Matched Description: … Penbutolol binds both beta-1 and beta-2 adrenergic receptors, rendering it a non-selective beta-blocker ... Penbutolol is contraindicated in patients with cardiogenic shock, sinus bradycardia, second and third ... degree atrioventricular conduction block, bronchial asthma, and those with known hypersensitivity. …
Matched Salts cas: … 38363-32-5 …
Matched Categories: … Cytochrome P-450 Substrates ... Cytochrome P-450 CYP2D6 Substrates ... penbutolol and other diuretics …
Matched Products: … BETAPRESSİN 40 MG FİLM TABLET, 30 TABLET …
Approved
Experimental
Matched Synonyms: … Sodium molybdate(VI) ... Molybdenum (as sodium) ... Anhydric sodium molybdate …
Matched Name: … Sodium molybdate …
Matched Salts cas: … 10102-40-6 …
Matched Mixtures name: … One Per Day Vitamin and Mineral Dietary Supplement ... DAILY-ONE 45 FILM TABLET ... VI-MINERAL 30 CIGNEME TABLETI …
Matched Salts name: … Sodium molybdate dihydrate …
Approved
Vet approved
Withdrawn
Matched Synonyms: … 3-(4-chlorophenoxy)-1,2-propanediol-1-carbamate ... 1,2-propanediol-3-(p-chlorophenoxy)-1-carbamate ... 3-(p-chlorophenoxy)-2-hydroxypropyl carbamate …
Matched Iupac: … 3-(4-chlorophenoxy)-2-hydroxypropyl carbamate …
Experimental
Matched Name: … (4-{4-[(TERT-BUTOXYCARBONYL)AMINO]-2,2-BIS(ETHOXYCARBONYL)BUTYL}PHENYL)SULFAMIC ACID …
Matched Iupac: … N-{4-[2-(2-{[(tert-butoxy)carbonyl]amino}ethyl)-3-ethoxy-2-(ethoxycarbonyl)-3-oxopropyl]phenyl}sulfamic …
The major hormone derived from the thyroid gland. Thyroxine is synthesized via the iodination of tyrosines (monoiodotyrosine) and the coupling of iodotyrosines (diiodotyrosine) in the thyroglobulin. Thyroxine is released from thyroglobulin by proteolysis and secreted into the blood. Thyroxine is peripherally deiodinated to form triiodothyronine which exerts a broad spectrum...
Approved
Investigational
Matched Synonyms: … O-(4-hydroxy-3,5-diiodophenyl)-3,5-diiodo-D-tyrosine …
Matched Iupac: … (2R)-2-amino-3-[4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl]propanoic acid …
Matched Description: … Thyroxine is synthesized via the iodination of tyrosines (monoiodotyrosine) and the coupling of iodotyrosines ... Thyroxine is released from thyroglobulin by proteolysis and secreted into the blood. …
Matched Salts name: … Dextrothyroxine sodium
Matched Categories: … Amino Acids, Peptides, and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … Choloxin Tablet 4mg ... Choloxin - Tab 4mg
Prednisolone phosphate is a glucocorticoid similar to cortisol used for its anti-inflammatory, immunosuppressive, anti-neoplastic, and vasoconstrictive effects. Prednisolone phosphate was granted FDA Approval on 19 December 1973.
Approved
Vet approved
Matched Iupac: … {2-[(1R,3aS,3bS,9aR,9bS,10S,11aS)-1,10-dihydroxy-9a,11a-dimethyl-7-oxo-1H,2H,3H,3aH,3bH,4H,5H,7H,9aH, …
Matched Description: … glucocorticoid similar to [cortisol] used for its anti-inflammatory, immunosuppressive, anti-neoplastic, and
Matched Mixtures name: … Sulfacetamide Sodium and Prednisolone Sodium Phosphate ... Sulfacetamide Sodium and Prednisolone Sodium Phosphate ... Sulfacetamide Sodium and Prednisolone Sodium Phosphate …
Matched Salts name: … Prednisolone sodium phosphate …
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists ... Cytochrome P-450 CYP2A6 Inducers ... Cytochrome P-450 Substrates ... Cytochrome P-450 CYP2B6 Inducers ... Cytochrome P-450 CYP2C8 Inducers …
Matched Products: … PMS-prednisolone Sodium Phosphate Ophthalmic Solution Forte ... METICORTELONE® SOLUCION ORAL 3 MG /ML ... PMS-prednisolone …
An opioid analgesic structurally related to methadone and used in the treatment of severe pain. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1070)
Experimental
Illicit
Matched Synonyms: … (+)-4-(2-methyl-4-oxo-3,3-diphenyl-4-(1-pyrrolidinyl)butyl)morpholine ... 4-(2-methyl-4-oxo-3,3-diphenyl-4-(1-pyrrolidinyl)butyl)morpholine ... 1-((3S)-3-methyl-4-(4-morpholinyl)-1-oxo-2,2-diphenylbutyl)pyrrolidine …
Matched Iupac: … (3S)-3-methyl-4-(morpholin-4-yl)-2,2-diphenyl-1-(pyrrolidin-1-yl)butan-1-one …
Matched Description: … An opioid analgesic structurally related to methadone and used in the treatment of severe pain. …
Dequalinium is an antibacterial agent with multi-targeted actions. It also possesses antifungal, antiparasitic, antiviral, anticancer, and neuroprotective properties. It is a quaternary ammonium compound, as it consists of an amphipathic cation with two aminoquinaldinium rings at both ends of a long hydrophobic hydrocarbon chain. Due to its flexible structure, dequalinium...
Approved
Investigational
Matched Synonyms: … Decamethylenebis(4-aminoquinaldinium chloride) ... 1,1'-Decamethylenebis(4-aminoquinaldinium chloride) ... 1,1'-(1,10-Decanediyl)bis(4-amino-2-methylquinolinium) dichloride …
Matched Iupac: … 4-amino-1-[10-(4-amino-2-methylquinolin-1-ium-1-yl)decyl]-2-methylquinolin-1-ium …
Matched Description: … It also possesses antifungal, antiparasitic, antiviral, anticancer, and neuroprotective properties. ... various OTC products to treat conditions of oral infections and inflammation. ... Due to its flexible structure, dequalinium was investigated to build drug and gene delivery systems. …
Matched Salts name: … Dequalinium bromide ... Dequalinium chloride
Matched Categories: … Antiseptics and Disinfectants ... Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics …
Experimental
Matched Synonyms: … Fazadinium bromide
Matched Name: … Fazadinium bromide
Matched Iupac: … 3-methyl-1-[(E)-2-{3-methyl-2-phenyl-1H-4lambda5-imidazo[1,2-a]pyridin-4-ylium-1-yl}diazen-1-yl]-2-phenyl ... -1H-4lambda5-imidazo[1,2-a]pyridin-4-ylium dibromide …
Matched Categories: … fazadinium bromide
Experimental
Matched Name: … 2,5-dichloro-N-(3,5-dibromo-4-hydroxyphenyl)benzamide …
Matched Iupac: … 2,5-dichloro-N-(3,5-dibromo-4-hydroxyphenyl)benzamide …
Sulindac is a nonsteroidal anti-inflammatory drug (NSAID) of the arylalkanoic acid class that is marketed by Merck under the brand name Clinoril. Like other NSAIDs, it may be used in the treatment of acute or chronic inflammatory conditions. Sulindac is a prodrug, derived from sulfinylindene, that is converted in vivo...
Approved
Investigational
Matched Synonyms: … cis-5-Fluoro-2-methyl-1-((4-(methylsulfinyl)phenyl)methylene)-1H-indene-3-acetic acid ... (Z)-5-Fluoro-2-methyl-1-((p-(methylsulfinyl)phenyl)methylene)-1H-indene-3-acetic acid ... cis-5-Fluoro-2-methyl-1-((p-methylsulfinyl)benzylidene)indene-3-acetic acid …
Matched Iupac: … 2-[(1Z)-5-fluoro-1-[(4-methanesulfinylphenyl)methylidene]-2-methyl-1H-inden-3-yl]acetic acid …
Matched Description: … levels of the compound without inducing gastrointestinal effects, where the drug is excreted in the bile and ... is thought to primarily mediate its action by inhibiting prostaglandin synthesis by inhibiting COX-1 and
Matched Salts name: … Sulindac sodium
Matched Categories: … Acetic Acid Derivatives and Related Substances ... Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids …
Felodipine is a long-acting 1,4-dihydropyridine calcium channel blocker (CCB)b. It acts primarily on vascular smooth muscle cells by stabilizing voltage-gated L-type calcium channels in their inactive conformation. By inhibiting the influx of calcium in smooth muscle cells, felodipine prevents calcium-dependent myocyte contraction and vasoconstriction. Felodipine is the most potent CCB...
Approved
Investigational
Matched Synonyms: … 3-ethyl 5-methyl 4-(2,3-dichlorophenyl)-2,6-dimethyl-1,4-dihydro-3,5-pyridinedicarboxylate ... (±)-ethyl methyl 4-(2,3-dichlorophenyl)-1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylate ... 4-(2,3-dichlorophenyl)-1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylic acid ethyl methyl ester …
Matched Iupac: … 3-ethyl 5-methyl 4-(2,3-dichlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate …
Matched Description: … influx of calcium in smooth muscle cells, felodipine prevents calcium-dependent myocyte contraction and ... Felodipine is the most potent CCB in use and is unique in that it exhibits fluorescent activity. ... mineralcorticoid receptor, inhibits the activity of calmodulin-dependent cyclic nucleotide phosphodiesterase, and
Matched Mixtures name: … DELIX DUO 2.5 MG/2.5 MG TABLET, 30 ADET ... DELIX DUO 5 MG/5 MG FİLM KAPLI TABLET, 30 ADET …
Matched Categories: … ACE Inhibitors and Calcium Channel Blockers ... Beta blocking agents and calcium channel blockers ... Calcium-Regulating Hormones and Agents ... ramipril and felodipine ... metoprolol and felodipine …
Experimental
Matched Synonyms: … Butan-1-ol ... N-butyl alcohol …
Matched Name: … Butyl alcohol …
Matched Iupac: … butan-1-ol …
Iodide I-123 (as sodium Iodide I-123) is a radioactive isotope of iodine used in nuclear medicine for the diagnostic study of thyroid disease. Following oral administration, I-123 is absorbed through the gastrointestinal tract and is taken up by the thyroid gland. After incorporation, a gamma camera is used to detect...
Approved
Matched Synonyms: … Iodide ion i-123 …
Matched Description: … Following oral administration, I-123 is absorbed through the gastrointestinal tract and is taken up by ... for formation of the thyroid hormones triiodothyronine (T3) and its prohormone, thyroxine (T4). ... use as its half-life of approximately 13.13 h (hours) is ideal for the 24-h (hour) iodine uptake test and
Matched Salts name: … Sodium iodide I-123 …
Matched Categories: … sodium iodide (123I) …
Matched Products: … Sodium Iodide ... Sodium Iodide I 123 ... SODIO IODURO (123I) GE HEALTHCARE …
MPB-1523 is a contrast agent comprising PEGylated iron oxide nanoparticles.
Investigational
Matched Synonyms: … PEGylated iron oxide nanoparticles …
Matched Description: … MPB-1523 is a contrast agent comprising PEGylated iron oxide nanoparticles.[L48161] …
Displaying drugs 726 - 750 of 5758 in total