Displaying drugs 726 - 750 of 1316 in total
humanized SMART Anti-IL-12 Antibody
The humanized anti-IL-12 antibody is an important addition to PDL's already strong pipeline of humanized antibodies being developed for the treatment of autoimmune diseases. SMART Anti-IL-12 Antibody was humanized at PDL from a murine anti-IL-12 antibody that was licensed, together with certain intellectual property related to anti-IL-12 therapy, from Hoffmann-La...
Investigational
Matched Name: … humanized SMART Anti-IL-12 Antibody …
Matched Description: … SMART Anti-IL-12 Antibody was humanized at PDL from a murine anti-IL-12 antibody that was licensed, together ... The humanized anti-IL-12 antibody is an important addition to PDL's already strong pipeline of humanized …
Matched Description: … SMART Anti-IL-12 Antibody was humanized at PDL from a murine anti-IL-12 antibody that was licensed, together ... The humanized anti-IL-12 antibody is an important addition to PDL's already strong pipeline of humanized …
pM-81
Investigational
Matched Synonyms: … Monoclonal antibody PM-81 ... Anti-CD15 monoclonal antibody PM-81 ... Anti-AML/SCCL-trigger monoclonal antibody …
Sabatolimab
Sabatolimab is under investigation in clinical trial NCT03946670 (A Study of MBG453 in Combination With Hypomethylating Agents in Subjects With IPSS-R Intermediate, High or Very High Risk Myelodysplastic Syndrome (MDS).).
Investigational
Matched Synonyms: … Anti-tim-3 monoclonal antibody mbg453 ... 2) (human-mus musculus monoclonal clone nvs260714 .gamma.4-chain), disulfide with human-mus musculus ... receptor 2, t-cell immunoglobulin mucin family member 3, tim-3, tim3, timd3, cd366)), humanized monoclonal antibody …
Matched Categories: … MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES ... Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents …
Matched Categories: … MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES ... Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents …
Cholecystokinin
Cholecystokinin ( also known as CCK or CCK-PZ) is a peptide hormone of the gastrointestinal system which is responsible for stimulating the digestion of fat and protein. Cholecystokinin, previously called pancreozymin, is synthesized and secreted by enteroendocrine cells in the duodenum (the first portion of the small intestine) and leads...
Approved
Investigational
Matched Synonyms: … Human CCK-33 ... Human cholecystokinin-33 …
Matched Description: … in the duodenum (the first portion of the small intestine) and leads to the release of bile and digestive ... peptide hormone of the gastrointestinal system which is responsible for stimulating the digestion of fat and ... Cholecystokinin, previously called _pancreozymin_, is synthesized and secreted by enteroendocrine cells …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Cholagogues and Choleretics ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Description: … in the duodenum (the first portion of the small intestine) and leads to the release of bile and digestive ... peptide hormone of the gastrointestinal system which is responsible for stimulating the digestion of fat and ... Cholecystokinin, previously called _pancreozymin_, is synthesized and secreted by enteroendocrine cells …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Cholagogues and Choleretics ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Thrombin alfa
Thrombin Alfa is a human coagulation protein produced via recombinant DNA technology from a genetically modified CHO cell line. Thrombin Alfa is identical in amino acid sequence and structurally similar to naturally occurring human thrombin. Thrombin Alfa precursor is secreted to culture medium as single chain form that is proteolytically...
Approved
Matched Synonyms: … Thrombin (synthetic human) ... Human Thrombin (recombinant, glycosylated) …
Matched Description: … Thrombin Alfa is identical in amino acid sequence and structurally similar to naturally occurring human ... that is proteolytically converted to a two-chain active form (using a protein derived from snakes) and ... The cell line used to manufacture Thrombin Alfa has been tested and shown to be free of known infectious …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Enzymes and Coenzymes …
Matched Description: … Thrombin Alfa is identical in amino acid sequence and structurally similar to naturally occurring human ... that is proteolytically converted to a two-chain active form (using a protein derived from snakes) and ... The cell line used to manufacture Thrombin Alfa has been tested and shown to be free of known infectious …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Enzymes and Coenzymes …
Human botulinum neurotoxin A/B immune globulin
Infant botulism is a rare infectious disease occurring in infants in which Clostridium botulinum colonize the large intestine and being to produce botulinum neurotoxin directly in the gut. As these neurotoxins interfere with cholinergic nervous transmission, patients initially present with evident of loss of muscle tone (e.g. constipation, ptosis, feeding...
Approved
Matched Synonyms: … Botulism immune globulin IV human ... Botulism immune globulin intravenous (human) ... Human-derived botulism antitoxin antibodies …
Matched Name: … Human botulinum neurotoxin A/B immune globulin …
Matched Description: … Treatment and Prevention Program[L39829] and comprises IgG antibodies derived from pooled adult plasma ... [L39819,L39824] BabyBIG (human-derived botulism immunoglobulin) was approved for use by the FDA in ... infectious disease occurring in infants in which _Clostridium botulinum_ colonize the large intestine and …
Matched Categories: … Human Immunoglobulin G …
Matched Name: … Human botulinum neurotoxin A/B immune globulin …
Matched Description: … Treatment and Prevention Program[L39829] and comprises IgG antibodies derived from pooled adult plasma ... [L39819,L39824] BabyBIG (human-derived botulism immunoglobulin) was approved for use by the FDA in ... infectious disease occurring in infants in which _Clostridium botulinum_ colonize the large intestine and …
Matched Categories: … Human Immunoglobulin G …
Ocriplasmin
Ocriplasmin is a recombinant truncated form of human plasmin with a molecular weight of 27.2 kDa produced by recombinant DNA technology in a Pichia pastoris expression system. Ocriplasmin is a protein made up of 249 amino acids and has two peptide chains. Agent for pharmacologic vitreolysis; thrombolytic agent. FDA approved...
Approved
Matched Synonyms: … Microplasmin (synthetic human) ... Recombinant human microplasmin …
Matched Description: … Ocriplasmin is a protein made up of 249 amino acids and has two peptide chains. ... Ocriplasmin is a recombinant truncated form of human plasmin with a molecular weight of 27.2 kDa produced …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Enzymes and Coenzymes …
Matched Description: … Ocriplasmin is a protein made up of 249 amino acids and has two peptide chains. ... Ocriplasmin is a recombinant truncated form of human plasmin with a molecular weight of 27.2 kDa produced …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Enzymes and Coenzymes …
Pertuzumab
Pertuzumab is a recombinant humanized monoclonal antibody that targets the extracellular dimerization domain (subdomain II) of the human epidermal growth factor receptor 2 protein (HER2). It consists of two heavy chains and two lights chains that have 448 and 214 residues respectively. It was first approved by the FDA in...
Approved
Matched Synonyms: … 2C4 Antibody ... Monoclonal Antibody 2C4 …
Matched Description: … It consists of two heavy chains and two lights chains that have 448 and 214 residues respectively. ... It was first approved by the FDA in 2012 for use with [docetaxel] and another HER2-targeted monoclonal ... domain (subdomain II) of the human epidermal growth factor receptor 2 protein (HER2). …
Matched Categories: … MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES ... Amino Acids, Peptides, and Proteins ... HER2 (Human Epidermal Growth Factor Receptor 2) inhibitors ... pertuzumab and trastuzumab ... Antineoplastic and Immunomodulating Agents …
Matched Description: … It consists of two heavy chains and two lights chains that have 448 and 214 residues respectively. ... It was first approved by the FDA in 2012 for use with [docetaxel] and another HER2-targeted monoclonal ... domain (subdomain II) of the human epidermal growth factor receptor 2 protein (HER2). …
Matched Categories: … MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES ... Amino Acids, Peptides, and Proteins ... HER2 (Human Epidermal Growth Factor Receptor 2) inhibitors ... pertuzumab and trastuzumab ... Antineoplastic and Immunomodulating Agents …
BB-1701
BB-1701 is a humanized IgG1 kappa monoclonal antibody (anti-HER2 antibody) conjugated to eribulin developed by Bliss Biopharmaceutical.
Investigational
Matched Synonyms: … Humanized IgG1kappa monoclonal antibody (anti-HER2 antibody) conjugated to eribulin …
Matched Description: … BB-1701 is a humanized IgG1 kappa monoclonal antibody (anti-HER2 antibody) conjugated to eribulin developed …
Matched Description: … BB-1701 is a humanized IgG1 kappa monoclonal antibody (anti-HER2 antibody) conjugated to eribulin developed …
Anti-GD2 monoclonal antibody 3F8
Anti-GD2 monoclonal antibody 3F8 is under investigation in clinical trial NCT00089258 (Biological Therapy in Treating Patients With Neuroblastoma That Has Not Responded to Previous Treatment).
Investigational
Matched Synonyms: … MONOCLONAL ANTIBODY 3F8 ... ANTI-GD2 MOUSE MONOCLONAL ANTIBODY 3F8 (IGG3) …
Matched Name: … Anti-GD2 monoclonal antibody 3F8 …
Matched Description: … Anti-GD2 monoclonal antibody 3F8 is under investigation in clinical trial NCT00089258 (Biological Therapy …
Matched Name: … Anti-GD2 monoclonal antibody 3F8 …
Matched Description: … Anti-GD2 monoclonal antibody 3F8 is under investigation in clinical trial NCT00089258 (Biological Therapy …
GL-2045
Investigational
Matched Synonyms: … Recombinant human IgG1 Fc multimer ... Recombinant Multimerized Human IgG1 Fc …
Prothrombin
Prothrombin Complex Concentrate (Human), is indicated for the urgent reversal of acquired coagulation factor deficiency induced by Vitamin K antagonist (VKA, e.g., warfarin) therapy in adult patients with acute major bleeding.
Approved
Matched Synonyms: … Coagulation factor II human ... Coagulation factor II (human) ... Human coagulation factor II …
Matched Description: … Prothrombin Complex Concentrate (Human), is indicated for the urgent reversal of acquired coagulation …
Matched Mixtures name: … OCTAPLEX POWDER AND SOLVENT FOR SOLUTION FOR INJECTION 500 IU ... Octaplex Powder and Solvent for Solution for Infusion …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Enzymes and Coenzymes …
Matched Description: … Prothrombin Complex Concentrate (Human), is indicated for the urgent reversal of acquired coagulation …
Matched Mixtures name: … OCTAPLEX POWDER AND SOLVENT FOR SOLUTION FOR INJECTION 500 IU ... Octaplex Powder and Solvent for Solution for Infusion …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Enzymes and Coenzymes …
Albusomatropin
Albusomatropin has been used in trials studying the treatment of Growth Hormone-Deficiency and Growth Hormone Deficiency.
Investigational
Matched Synonyms: … recombinant human serum albumin human growth hormone ... RECOMBINANT HUMAN ALBUMIN-RECOMBINANT HUMAN GROWTH HORMONE FUSION PROTEIN ... HUMAN SERUM ALBUMIN FUSED TO THE N-TERMINUS OF GROWTH HORMONE …
Matched Description: … Albusomatropin has been used in trials studying the treatment of Growth Hormone-Deficiency and Growth …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Description: … Albusomatropin has been used in trials studying the treatment of Growth Hormone-Deficiency and Growth …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
3'-phospho-5'-adenylyl sulfate
3'-phospho-5'-adenylyl sulfate is a key intermediate in the formation by living cells of sulfate esters of phenols, alcohols, steroids, sulfated polysaccharides, and simple esters, such as choline sulfate. It is formed from sulfate ion and ATP in a two-step process. This compound also is an important step in the process...
Experimental
Matched Synonyms: … 3'-phosphoadenylyl sulfate …
Matched Name: … 3'-phospho-5'-adenylyl sulfate …
Matched Description: … It is formed from sulfate ion and ATP in a two-step process. ... of phenols, alcohols, steroids, sulfated polysaccharides, and simple esters, such as choline sulfate ... This compound also is an important step in the process of sulfur fixation in plants and microorganisms …
Matched Name: … 3'-phospho-5'-adenylyl sulfate …
Matched Description: … It is formed from sulfate ion and ATP in a two-step process. ... of phenols, alcohols, steroids, sulfated polysaccharides, and simple esters, such as choline sulfate ... This compound also is an important step in the process of sulfur fixation in plants and microorganisms …
Recombinant human plasma gelsolin
Plasma gelsolin (pGSN) is a protein found in the blood of healthy individuals which scavenges compounds left over from damaged tissues.
Investigational
Matched Synonyms: … Recombinant human gelsolin …
Matched Name: … Recombinant human plasma gelsolin …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intracellular Signaling Peptides and Proteins ... Calcium-Binding Proteins ... Intracellular Calcium-Sensing Proteins …
Matched Name: … Recombinant human plasma gelsolin …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intracellular Signaling Peptides and Proteins ... Calcium-Binding Proteins ... Intracellular Calcium-Sensing Proteins …
Apamistamab iodine I-131
Investigational
Matched Synonyms: … 131I-BC8 monoclonal antibody (Anti-CD45 murine monoclonal antibody radiolabeled with 131I ... Immunoglobulin G1, anti-(human CD45 antigen) (mus musculus monoclonal BC8 gamma1-chain), disulfide with …
Coagulation factor X human
Coagulation Factor X (Human), is a plasma-derived human blood coagulation factor is used by adults and children (aged 12 years and above) with hereditary Factor X deficiency. However its use is limited in the perioperative setting for the management of bleeding in major surgery in patients with moderate and severe...
Approved
Investigational
Matched Synonyms: … Coagulation factor X (human) ... Human coagulation factor X …
Matched Name: … Coagulation factor X human …
Matched Description: … Coagulation Factor X (Human), is a plasma-derived human blood coagulation factor is used by adults and ... children (aged 12 years and above) with hereditary Factor X deficiency. ... the perioperative setting for the management of bleeding in major surgery in patients with moderate and …
Matched Mixtures name: … OCTAPLEX POWDER AND SOLVENT FOR SOLUTION FOR INJECTION 500 IU ... Octaplex Powder and Solvent for Solution for Infusion …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Blood and Blood Forming Organs ... Enzymes and Coenzymes …
Matched Name: … Coagulation factor X human …
Matched Description: … Coagulation Factor X (Human), is a plasma-derived human blood coagulation factor is used by adults and ... children (aged 12 years and above) with hereditary Factor X deficiency. ... the perioperative setting for the management of bleeding in major surgery in patients with moderate and …
Matched Mixtures name: … OCTAPLEX POWDER AND SOLVENT FOR SOLUTION FOR INJECTION 500 IU ... Octaplex Powder and Solvent for Solution for Infusion …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Blood and Blood Forming Organs ... Enzymes and Coenzymes …
Interleukin-15, human recombinant
Investigational
Matched Synonyms: … Human IL-15 …
Matched Name: … Interleukin-15, human recombinant …
Matched Name: … Interleukin-15, human recombinant …
Recombinant soluble human CD4
Investigational
Matched Synonyms: … Recombinant soluble CD4 (human) …
Matched Name: … Recombinant soluble human CD4 …
Matched Name: … Recombinant soluble human CD4 …
Protein C
Protein C is an endogenously occurring plasma protein that plays a key role within the coagulation cascade. Protein C is a zymogen, or enzyme precursor, of a vitamin K-dependent anticoagulant glycoprotein (serine protease) that is synthesized in the liver. It is converted by the thrombin/thrombomodulin-complex on the endothelial cell surface...
Approved
Matched Synonyms: … Human protein C ... Protein C human ... Protein C concentrate human …
Matched Description: … thrombosis and purpura fulminans. ... its effect by inactivating essential components of the coagulation cascade (specifically factors V and ... VIII), which leads to a decrease in thrombin formation, and therefore a reduction in clot formation. …
Matched Mixtures name: … OCTAPLEX POWDER AND SOLVENT FOR SOLUTION FOR INJECTION 500 IU ... Octaplex Powder and Solvent for Solution for Infusion …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Blood and Blood Forming Organs ... Enzymes and Coenzymes …
Matched Description: … thrombosis and purpura fulminans. ... its effect by inactivating essential components of the coagulation cascade (specifically factors V and ... VIII), which leads to a decrease in thrombin formation, and therefore a reduction in clot formation. …
Matched Mixtures name: … OCTAPLEX POWDER AND SOLVENT FOR SOLUTION FOR INJECTION 500 IU ... Octaplex Powder and Solvent for Solution for Infusion …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Blood and Blood Forming Organs ... Enzymes and Coenzymes …
Plasminogen
Plasminogen is a pro-enzyme (i.e. a zymogen) which is cleaved to form plasmin - also known as fibrinolysin - as part of the fibrinolytic pathway that breaks down fibrin blood clots. This pathway is activated when a clot is no longer needed or to prevent a clot from extending beyond...
Approved
Matched Synonyms: … Human plasminogen ... plasminogen, human-tvmh …
Matched Description: … [L34615] It is the first and only FDA-approved treatment for this condition, which causes wood-like lesions ... [L34635] In June 2021, the FDA approved a plasma-derived plasminogen (Ryplazim, human plasminogen-tvmh …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Enzymes and Coenzymes …
Matched Description: … [L34615] It is the first and only FDA-approved treatment for this condition, which causes wood-like lesions ... [L34635] In June 2021, the FDA approved a plasma-derived plasminogen (Ryplazim, human plasminogen-tvmh …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Enzymes and Coenzymes …
Netakimab
Netakimab is under investigation in clinical trial NCT03447704 (International Multicenter Comparative Randomized Placebo-controlled Clinical Study of Efficacy and Safety of BCD-085 in Patients With Ankylosing Spondylitis).
Investigational
Matched Synonyms: … Immunoglobulin g1, anti-(human interleukin 17) (human-lama glama monoclonal heavy chain), disulfide with ... human monoclonal light chain, dimer …
Matched Description: … NCT03447704 (International Multicenter Comparative Randomized Placebo-controlled Clinical Study of Efficacy and …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents …
Matched Description: … NCT03447704 (International Multicenter Comparative Randomized Placebo-controlled Clinical Study of Efficacy and …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents …
Terbutaline
Terbutaline was first synthesized in 1966 and described in the literature in the late 1960s and early 1970s. It is a selective beta-2 adrenergic agonist used as a bronchodilator in asthmatic patients.[A230333,L32093,L32098]
Terbutaline was granted FDA approval on 25 March 1974.
Approved
Matched Description: … and early 1970s. ... Terbutaline was first synthesized in 1966[A230333] and described in the literature in the late 1960s …
Matched Salts name: … Terbutaline sulfate …
Matched Products: … Terbutaline Sulfate ... TERBUTALINE SULFATE …
Matched Salts name: … Terbutaline sulfate …
Matched Products: … Terbutaline Sulfate ... TERBUTALINE SULFATE …
Displaying drugs 726 - 750 of 1316 in total