Displaying drugs 7551 - 7575 of 12049 in total
p-Toluenesulfonic acid
Experimental
Matched Synonyms: … 4-toluenesulfonic acid ... toluene-4-sulfonic acid …
Matched Iupac: … 4-methylbenzene-1-sulfonic acid …
Matched Iupac: … 4-methylbenzene-1-sulfonic acid …
Secoisolariciresinol
Secoisolariciresinol has been used in trials studying the prevention of Breast Cancer.
Investigational
Matched Iupac: … (2R,3R)-2,3-bis[(4-hydroxy-3-methoxyphenyl)methyl]butane-1,4-diol …
2-Methoxyestradiol
2-Methoxyestradiol (2ME2) is a drug that prevents the formation of new blood vessels that tumors need in order to grow (angiogenesis). It has undergone Phase 1 clinical trials against breast cancers and preclinical studies suggest that 2ME2 could also be effective against inflammatory diseases such as rheumatoid arthritis.
Investigational
Matched Description: … It has undergone Phase 1 clinical trials against breast cancers and preclinical studies suggest that …
3-amino-5-phenylpentane
3-amino-5-phenylpentane is a solid. This compound belongs to the phenylpropylamines. These are compounds containing a phenylpropylamine moiety, which consists of a phenyl group substituted at the third carbon by a propan-1-amine. 3-amino-5-phenylpentane targets the proteins cathepsin K and cathepsin L2.
Experimental
Matched Name: … 3-amino-5-phenylpentane …
Matched Iupac: … (3S)-1-(benzenesulfonyl)-5-phenylpent-1-en-3-amine …
Matched Description: … phenylpropylamine moiety, which consists of a phenyl group substituted at the third carbon by a propan-1- ... 3-amino-5-phenylpentane is a solid. This compound belongs to the phenylpropylamines. ... amine. 3-amino-5-phenylpentane targets the proteins cathepsin K and cathepsin L2. …
Matched Iupac: … (3S)-1-(benzenesulfonyl)-5-phenylpent-1-en-3-amine …
Matched Description: … phenylpropylamine moiety, which consists of a phenyl group substituted at the third carbon by a propan-1- ... 3-amino-5-phenylpentane is a solid. This compound belongs to the phenylpropylamines. ... amine. 3-amino-5-phenylpentane targets the proteins cathepsin K and cathepsin L2. …
Bisegliptin
Bisegliptin is a compound for the treatment of type 2 diabetes. It is an orally active, dipeptidyl peptidase-IV (DPPIV) inhibitor which lowers blood glucose levels by blocking the degradation of the hormone GLP-1 thereby stimulating glucose-dependent insulin secretion and lowering blood glucose levels without hypoglycemic effects.
Investigational
Matched Iupac: … ethyl 4-({2-[(2S,4S)-2-cyano-4-fluoropyrrolidin-1-yl]-2-oxoethyl}amino)bicyclo[2.2.2]octane-1-carboxylate …
Matched Description: … (DPPIV) inhibitor which lowers blood glucose levels by blocking the degradation of the hormone GLP-1 …
Matched Description: … (DPPIV) inhibitor which lowers blood glucose levels by blocking the degradation of the hormone GLP-1 …
Barbexaclone
Barbexaclone, a salt compound of propylhexedrine and phenobarbital, is a potent antiepileptic. By weight, barbexaclone is 40% propylhexedrine and 60% phenobarbital. While barbexaclone has sedative properties, propylhexedrine has psychostimulant properties intended to offset these sedative effects. Pharmacokinetic studies have demonstrated that the pharmacokinetics of phenobarbital given as barbexaclone are not...
Experimental
Matched Iupac: … 5-ethyl-5-phenyl-1,3-diazinane-2,4,6-trione; [(2S)-1-cyclohexylpropan-2-yl](methyl)amine …
Matched Description: … By weight, barbexaclone is 40% propylhexedrine and 60% phenobarbital. …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Description: … By weight, barbexaclone is 40% propylhexedrine and 60% phenobarbital. …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Adrafinil
Adrafinil is a mild central nervous system stimulating drug typically employed to relieve excessive sleepiness and inattention in geriatric patients. It is also been used off-label to prevent fatigue or falling asleep for extended periods of time. Adrafinil does not currently have FDA approval and is thus unregulated in the...
Withdrawn
Cerulenin
Cerulenin is an antifungal agent whose activity interferes with or otherwise acts to prevent the formation of fatty acids and sterols. In fatty acid synthesis, reported to bind in equimolar ratio to b-keto-acyl-ACP synthase. In sterol synthesis, inhibits HMG-CoA synthetase activity. It is also shown to inhibit feeding and induce...
Experimental
Mito-4509
Mito-4509 is a non-feminizing estrogen analog that could affect mitochondrial metabolic pathways. It is used to treat Parkinson's Disease, Alzheimer's Disease, Retinal Disorders and other neurologic Disorders.
Investigational
GW-406381
GW-406381 has been used in trials studying the treatment of Pain, Trauma, Neurodynia, Dental Pain, and Hyperalgesia, among others.
Investigational
Matched Iupac: … 2-(4-ethoxyphenyl)-3-(4-methanesulfonylphenyl)pyrazolo[1,5-b]pyridazine …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
CG-400549
CG400549 has been used in trials studying the treatment of Skin Infection.
Investigational
Matched Iupac: … 1-[(3-amino-2-methylphenyl)methyl]-4-[2-(thiophen-2-yl)ethoxy]-1,2-dihydropyridin-2-one …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
GW-468816
GW-468816 is under investigation in clinical trial NCT00218465 (Effectiveness of GW468816, an NMDA Glycine Site Antagonist, for Prevention of Relapse to Smoking).
Investigational
Matched Iupac: … (2R)-7-chloro-4-[(3E)-2-oxo-1-phenylpyrrolidin-3-ylidene]-1,2,3,4-tetrahydroquinoline-2-carboxylic acid …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
GS-441524
GS-441524 is an adenosine nucleotide analog antiviral, similar to remdesivir.[A203057,L13239] This molecule was patented in 2009. In vitro studies of GS-441524 have determined it has a higher EC50 than remdesivir against a number of viruses, meaning GS-441524 is less potent.[A203057,A203057] GS-441524 continues to be studied in the treatment of Feline...
Experimental
Matched Iupac: … (2R,3R,4S,5R)-2-{4-aminopyrrolo[2,1-f][1,2,4]triazin-7-yl}-3,4-dihydroxy-5-(hydroxymethyl)oxolane-2-carbonitrile …
5-{3-[3-(2,4-DICHLORO-BENZOYL)-UREIDO]-2-METHYL-PHENOXY}-PENTANOIC ACID
Experimental
Matched Name: … 5-{3-[3-(2,4-DICHLORO-BENZOYL)-UREIDO]-2-METHYL-PHENOXY}-PENTANOIC ACID …
Matched Iupac: … 5-(3-{[(2,4-dichlorobenzoyl)carbamoyl]amino}-2-methylphenoxy)pentanoic acid …
Matched Iupac: … 5-(3-{[(2,4-dichlorobenzoyl)carbamoyl]amino}-2-methylphenoxy)pentanoic acid …
2-[(3-Hydroxy-2-Methyl-5-Phosphonooxymethyl-Pyridin-4-Ylmethyl)-Imino]-5-Phosphono-Pent-3-Enoic Acid
Experimental
Matched Name: … 2-[(3-Hydroxy-2-Methyl-5-Phosphonooxymethyl-Pyridin-4-Ylmethyl)-Imino]-5-Phosphono-Pent-3-Enoic Acid …
Matched Iupac: … (2E,3E)-2-[({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methyl)imino]-5-phosphonopent-3- …
Matched Iupac: … (2E,3E)-2-[({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methyl)imino]-5-phosphonopent-3- …
4,4'-Biphenyldiboronic Acid
Experimental
Matched Iupac: … [4'-(dihydroxyboranyl)-[1,1'-biphenyl]-4-yl]boronic acid …
4-(4-Chlorophenyl)Imidazole
Experimental
Matched Name: … 4-(4-Chlorophenyl)Imidazole …
Matched Iupac: … 5-(4-chlorophenyl)-1H-imidazole …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Iupac: … 5-(4-chlorophenyl)-1H-imidazole …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Crovalimab
Crovalimab is under investigation in clinical trial NCT03157635 (Study to Assess Safety, Efficacy, Pharmacokinetics, and Pharmacodynamics of Crovalimab in Healthy Volunteers and Participants With Paroxysmal Nocturnal Hemoglobinuria).
Investigational
Carboxymethylthio-3-(3-Chlorophenyl)-1,2,4-Oxadiazol
Experimental
Matched Iupac: … 2-{[3-(3-chlorophenyl)-1,2,4-oxadiazol-5-yl]sulfanyl}acetic acid …
XL784
XL784 is a potent inhibitor of the ADAM-10 metalloprotease enzyme, a target of significant interest because of its important role in blood vessel formation and cell proliferation. XL784 was specifically optimized to be MMP-1 sparing, thus potentially enhancing its safety profile and enabling higher dosing compared with other previously studied...
Investigational
Matched Description: … XL784 was specifically optimized to be MMP-1 sparing, thus potentially enhancing its safety profile and …
DAS-431 IV
DAS-431 IV is a dopamine D1 receptor agonist developed by DrugAbuse Sciences for the treatment of Addictions, Schizophrenia, Schizoaffective Disorders, Dementia, Parkinson's Disease, Strokes etc.
Investigational
KB407
Investigational
Tarcocimab tedromer
Tarcocimab tedromer is under investigation in clinical trial NCT06270836 (A Study to Evaluate the Efficacy and Safety of Tarcocimab Tedromer Compared With Sham Treatment in Participants With Moderately Severe to Severe Non-proliferative Diabetic Retinopathy (NPDR)).
Investigational
2-MERCAPTO-N-[1,2,3,10-TETRAMETHOXY-9-OXO-5,6,7,9-TETRAHYDRO-BENZO[A]HEPTALEN-7-YL]ACETAMIDE
Experimental
Matched Iupac: … 2-sulfanyl-N-[(10S)-3,4,5,14-tetramethoxy-13-oxotricyclo[9.5.0.0^{2,7}]hexadeca-1(16),2(7),3,5,11,14- …
VB-309
Investigational
Matched Iupac: … yl]oxy}-4,5-dihydroxy-2-(hydroxymethyl)oxan-3-yl]oxy}-6-(hydroxymethyl)oxane-3,4,5-triol ... )-2-{[(2R,3S,4R,5R,6S)-6-{[(6aR,10aR)-6,6,9-trimethyl-3-pentyl-6H,6aH,7H,8H,10aH-benzo[c]isochromen-1- …
Displaying drugs 7551 - 7575 of 12049 in total