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Displaying drugs 7701 - 7725 of 10582 in total

BAY-876

Experimental
Matched Iupac: … N4-{1-[(4-cyanophenyl)methyl]-5-methyl-3-(trifluoromethyl)-1H-pyrazol-4-yl}-7-fluoroquinoline-2,4-dicarboxamide …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Inolimomab

Inolimomab is under investigation as an agent to treat steroid-resistant graft vs host disease. It has thus far offered similar efficacy to other monoclonal antibody options, though it may carry a higher risk of infections.
Investigational

Dimethylaminomicheliolide

Investigational
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Imidazole

Experimental
Investigational
Matched Categories: … Heterocyclic Compounds, 1-Ring …

SB220025

Experimental
Matched Iupac: … 4-[4-(4-fluorophenyl)-1-(piperidin-4-yl)-1H-imidazol-5-yl]pyrimidin-2-amine …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

KD3010

KD3010 is a small molecule peroxisome proliferator-activator receptor delta (PPAR Delta) agonist for the treatment of metabolic disorders, including obesity.
Investigational
Matched Iupac: … 4-methylbenzene-1-sulfonic acid; 4-{[(2R,6S)-2,6-dimethyl-4-[4-(trifluoromethoxy)phenyl]piperazin-1-yl …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Oxypurinol

Oxypurinol, an inhibitor of xanthine oxidase, is a metabolite of allopurinol.
Investigational
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Buparlisib

Buparlisib has been used in trials studying the treatment and basic science of Lymphoma, Metastases, Lung Cancer, Solid Tumors, and Breast Cancer, among others.
Investigational
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Pevonedistat

Pevonedistat has been used in trials studying the treatment of Lymphoma, Solid Tumors, Multiple Myeloma, Hodgkin Lymphoma, and Metastatic Melanoma, among others.
Investigational
Matched Iupac: … [(1S,2S,4R)-4-(4-{[(1S)-2,3-dihydro-1H-inden-1-yl]amino}-7H-pyrrolo[2,3-d]pyrimidin-7-yl)-2-hydroxycyclopentyl …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Ralimetinib

Ralimetinib has been used in trials studying the treatment of Postmenopausal, Advanced Cancer, Adult Glioblastoma, Fallopian Tube Cancer, and Metastatic Breast Cancer, among others.
Investigational
Matched Salts cas: … 862507-23-1 …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Tegobuvir

Tegobuvir has been investigated for the treatment of Hepatitis C, Chronic.
Investigational
Matched Categories: … Heterocyclic Compounds, 1-Ring …

AZD-3839

AZD3839 has been used in trials studying the basic science of Safety, Tolerability, Alzheimer's Disease, and Blood Concentration.
Investigational
Matched Iupac: … (1S)-1-[2-(difluoromethyl)pyridin-4-yl]-4-fluoro-1-[3-(pyrimidin-5-yl)phenyl]-1H-isoindol-3-amine …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Nelivaptan

Nelivaptan has been used in trials studying the treatment of Anxiety Disorders, Depressive Disorder, and Major Depressive Disorder.
Investigational
Matched Iupac: … (2S,4R)-1-[(3R)-5-chloro-1-(2,4-dimethoxybenzenesulfonyl)-3-(2-methoxyphenyl)-2-oxo-2,3-dihydro-1H-indol …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Nerispirdine

Nerispirdine has been used in trials studying the treatment of Neuritis, Optic Nerve, and Multiple Sclerosis.
Investigational
Matched Iupac: … N-(3-fluoropyridin-4-yl)-3-methyl-N-propyl-1H-indol-1-amine …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Turofexorate isopropyl

Fxr 450 is under investigation in clinical trial NCT00509756 (Study Evaluating Turofexorate isopropyl in Healthy Japanese Men).
Investigational
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Milademetan

Milademetan is under investigation in clinical trial NCT02319369 (Safety, Tolerability and Pharmacokinetics of Milademetan Alone and With 5-Azacitidine (AZA) in Acute Myelogenous Leukemia (AML) or High-Risk Myelodysplastic Syndrome (MDS)).
Investigational
Matched Iupac: … N-[(3R,6S)-6-carbamoyloxan-3-yl]-6''-chloro-4'-(2-chloro-3-fluoropyridin-4-yl)-4,4-dimethyl-2''-oxo-1' …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Ravoxertinib

Ravoxertinib is under investigation in clinical trial NCT01875705 (A Dose-Escalation Study of GDC-0994 in Patients With Locally Advanced or Metastatic Solid Tumors).
Investigational
Matched Iupac: … 1-[(1S)-1-(4-chloro-3-fluorophenyl)-2-hydroxyethyl]-4-{2-[(1-methyl-1H-pyrazol-5-yl)amino]pyrimidin-4 …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

SY-5609

Investigational
Matched Categories: … Heterocyclic Compounds, 1-Ring …

GT 389-255

Peptimmune’s lead product GT 389-255, is a novel lipase inhibitor and fat binding hydrogel polymer conjugate for the treatment of obesity which has completed single and multiple ascending dose (SAD and MAD) Phase I trials. It is expected to block fat absorption with fewer side effects than currently marketed lipase...
Investigational

Propentofylline

Investigational
Matched Iupac: … 3-methyl-1-(5-oxohexyl)-7-propyl-2,3,6,7-tetrahydro-1H-purine-2,6-dione …

Sparsomycin

An antitumor antibiotic produced by Streptomyces sparsogenes. It inhibits protein synthesis in 70S and 80S ribosomal systems. [PubChem]
Experimental
Matched Iupac: … (2E)-N-[(2S)-1-hydroxy-3-[(R)-(methylsulfanyl)methanesulfinyl]propan-2-yl]-3-(6-methyl-2,4-dioxo-1,2,3,4 …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Ranirestat

Ranirestat is a structurally novel and stereospecifically potent aldose reductase (AKR1B; EC 1.1.1.21) inhibitor, which contains a succinimide ring that undergoes ring-opening at physiological pH levels. It has been used in trials studying the treatment of Mild to Moderate Diabetic Sensorimotor Polyneuropathy.
Investigational
Matched Iupac: … ]-1',2,3',5-tetrone ... (3R)-2'-[(4-bromo-2-fluorophenyl)methyl]-2',3'-dihydro-1'H-spiro[pyrrolidine-3,4'-pyrrolo[1,2-a]pyrazine …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Fevipiprant

Fevipiprant has been used in trials studying the treatment of Asthma, Atopic Dermatitis, and Allergic Rhinitis.
Investigational
Matched Iupac: … 2-(1-{[4-methanesulfonyl-2-(trifluoromethyl)phenyl]methyl}-2-methyl-1H-pyrrolo[2,3-b]pyridin-3-yl)acetic …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

CH-5132799

CH5132799 has been used in trials studying the treatment of Solid Tumors.
Investigational
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Butalamine

Experimental
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Displaying drugs 7701 - 7725 of 10582 in total