Displaying drugs 751 - 775 of 5715 in total
2-deoxy-2-fluoro-alpha-D-mannosyl fluoride
Experimental
Matched Name: … 2-deoxy-2-fluoro-alpha-D-mannosyl fluoride …
Matched Iupac: … (2R,3S,4S,5S)-5,6-difluoro-2-(hydroxymethyl)oxane-3,4-diol …
Matched Iupac: … (2R,3S,4S,5S)-5,6-difluoro-2-(hydroxymethyl)oxane-3,4-diol …
Azoximer bromide
Azoximer bromide is under investigation in clinical trial NCT04381377 (Efficacy and Safety of Polyoxidonium® in Hospitalized Patients With Coronavirus Disease COVID-19).
Investigational
Matched Synonyms: … Poly((1-(carboxymethyl)piperazin-1-ium-1,4-diyl bromide)ethylene-co-((piperazin-1,4-diyl 1-oxide)ethylene ... Azoximer bromide …
Matched Name: … Azoximer bromide …
Matched Description: … Azoximer bromide is under investigation in clinical trial NCT04381377 (Efficacy and Safety of Polyoxidonium …
Matched Name: … Azoximer bromide …
Matched Description: … Azoximer bromide is under investigation in clinical trial NCT04381377 (Efficacy and Safety of Polyoxidonium …
Sodium molybdate
Approved
Experimental
Matched Synonyms: … Sodium molybdate(VI) ... Molybdenum (as sodium) ... Anhydric sodium molybdate …
Matched Name: … Sodium molybdate …
Matched Salts cas: … 10102-40-6 …
Matched Mixtures name: … One Per Day Vitamin and Mineral Dietary Supplement ... DAILY-ONE 45 FILM TABLET ... VI-MINERAL 30 CIGNEME TABLETI …
Matched Salts name: … Sodium molybdate dihydrate …
Matched Name: … Sodium molybdate …
Matched Salts cas: … 10102-40-6 …
Matched Mixtures name: … One Per Day Vitamin and Mineral Dietary Supplement ... DAILY-ONE 45 FILM TABLET ... VI-MINERAL 30 CIGNEME TABLETI …
Matched Salts name: … Sodium molybdate dihydrate …
Sulindac
Sulindac is a nonsteroidal anti-inflammatory drug (NSAID) of the arylalkanoic acid class that is marketed by Merck under the brand name Clinoril. Like other NSAIDs, it may be used in the treatment of acute or chronic inflammatory conditions. Sulindac is a prodrug, derived from sulfinylindene, that is converted in vivo...
Approved
Investigational
Matched Synonyms: … cis-5-Fluoro-2-methyl-1-((4-(methylsulfinyl)phenyl)methylene)-1H-indene-3-acetic acid ... (Z)-5-Fluoro-2-methyl-1-((p-(methylsulfinyl)phenyl)methylene)-1H-indene-3-acetic acid ... cis-5-Fluoro-2-methyl-1-((p-methylsulfinyl)benzylidene)indene-3-acetic acid …
Matched Iupac: … 2-[(1Z)-5-fluoro-1-[(4-methanesulfinylphenyl)methylidene]-2-methyl-1H-inden-3-yl]acetic acid …
Matched Description: … levels of the compound without inducing gastrointestinal effects, where the drug is excreted in the bile and ... is thought to primarily mediate its action by inhibiting prostaglandin synthesis by inhibiting COX-1 and …
Matched Salts name: … Sulindac sodium …
Matched Categories: … Acetic Acid Derivatives and Related Substances ... Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids …
Matched Iupac: … 2-[(1Z)-5-fluoro-1-[(4-methanesulfinylphenyl)methylidene]-2-methyl-1H-inden-3-yl]acetic acid …
Matched Description: … levels of the compound without inducing gastrointestinal effects, where the drug is excreted in the bile and ... is thought to primarily mediate its action by inhibiting prostaglandin synthesis by inhibiting COX-1 and …
Matched Salts name: … Sulindac sodium …
Matched Categories: … Acetic Acid Derivatives and Related Substances ... Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids …
Valsartan
Valsartan belongs to the angiotensin II receptor blocker (ARB) family of drugs, which also includes telmisartan, candesartan, losartan, olmesartan, and irbesartan. ARBs selectively bind to angiotensin receptor 1 (AT1) and prevent the protein angiotensin II from binding and exerting its hypertensive effects, which include vasoconstriction, stimulation and synthesis of aldosterone...
Approved
Investigational
Matched Synonyms: … N-(P-(O-1H-Tetrazol-5-ylphenyl)benzyl)-N-valeryl-L-valine ... (S)-N-Valeryl-N-{[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]-methyl}-valine ... N-pentanoyl-N-{[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl}-L-valine …
Matched Iupac: … (2S)-3-methyl-2-(N-{[2'-(2H-1,2,3,4-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl]methyl}pentanamido)butanoic acid …
Matched Description: … cardiac activity, and increased excretion of sodium. ... aldosterone and ADH, cardiac stimulation, and renal reabsorption of sodium, among others. ... Overall, valsartan's physiologic effects lead to reduced blood pressure, lower aldosterone levels, reduced …
Matched Mixtures name: … DI-TANVLUR ... ONEPTUS 49 MG/51 MG FILM KAPLI TABLET, 56 ADET ... DIOVAN® HCT 320 / 12.5 MG …
Matched Categories: … Cytochrome P-450 Substrates ... Cytochrome P-450 CYP2C9 Inhibitors ... Cytochrome P-450 CYP2C9 Substrates ... Cytochrome P-450 Enzyme Inhibitors ... Cytochrome P-450 CYP2C9 Inhibitors (strength unknown) …
Matched Products: … PMS-valsartan ... Diovan 40 mg Filmtabletten ... DIOVAN 40 (TABLETS) …
Matched Iupac: … (2S)-3-methyl-2-(N-{[2'-(2H-1,2,3,4-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl]methyl}pentanamido)butanoic acid …
Matched Description: … cardiac activity, and increased excretion of sodium. ... aldosterone and ADH, cardiac stimulation, and renal reabsorption of sodium, among others. ... Overall, valsartan's physiologic effects lead to reduced blood pressure, lower aldosterone levels, reduced …
Matched Mixtures name: … DI-TANVLUR ... ONEPTUS 49 MG/51 MG FILM KAPLI TABLET, 56 ADET ... DIOVAN® HCT 320 / 12.5 MG …
Matched Categories: … Cytochrome P-450 Substrates ... Cytochrome P-450 CYP2C9 Inhibitors ... Cytochrome P-450 CYP2C9 Substrates ... Cytochrome P-450 Enzyme Inhibitors ... Cytochrome P-450 CYP2C9 Inhibitors (strength unknown) …
Matched Products: … PMS-valsartan ... Diovan 40 mg Filmtabletten ... DIOVAN 40 (TABLETS) …
Dexrazoxane
An antimitotic agent with immunosuppressive properties. Dexrazoxane, the (+)-enantiomorph of razoxane, provides cardioprotection against anthracycline toxicity. It appears to inhibit formation of a toxic iron-anthracycline complex. [PubChem]
The Food and Drug Administration has designated dexrazoxane as an orphan drug for use in the prevention or reduction in the incidence and...
Approved
Withdrawn
Matched Synonyms: … (+)-1,2-Bis(3,5-dioxo-1-piperazinyl)propane ... 4-[(2S)-2-(3,5-dioxopiperazin-1-yl)propyl]piperazine-2,6-dione ... (+)-(S)-4,4'-Propylenedi-2,6-piperazinedione …
Matched Iupac: … 4-[(2S)-1-(3,5-dioxopiperazin-1-yl)propan-2-yl]piperazine-2,6-dione …
Matched Description: … [PubChem] The Food and Drug Administration has designated dexrazoxane as an orphan drug for use in the ... prevention or reduction in the incidence and severity of anthracycline-induced cardiomyopathy. ... It appears to inhibit formation of a toxic iron-anthracycline complex. …
Matched Iupac: … 4-[(2S)-1-(3,5-dioxopiperazin-1-yl)propan-2-yl]piperazine-2,6-dione …
Matched Description: … [PubChem] The Food and Drug Administration has designated dexrazoxane as an orphan drug for use in the ... prevention or reduction in the incidence and severity of anthracycline-induced cardiomyopathy. ... It appears to inhibit formation of a toxic iron-anthracycline complex. …
Allitinib
Allitinib is under investigation in clinical trial NCT04671303 (To Evaluate the Efficacy and Safety of Anlotinib Combined With Allitinib in Lung Cancer).
Investigational
Matched Synonyms: … N-(4-((3-chloro-4-((3-fluorobenzyl)oxy)phenyl)amino)quinazolin-6-yl)acrylamide ... 2-propenamide, n-(4-((3-chloro-4-((3-fluorophenyl)methoxy)phenyl)amino)-6-quinazolinyl)- ... N-(4-((3-chloro-4-((3-fluorophenyl)methoxy)phenyl)amino)-6-quinazolinyl)-2-propenamide …
Matched Description: … Allitinib is under investigation in clinical trial NCT04671303 (To Evaluate the Efficacy and Safety of …
Matched Description: … Allitinib is under investigation in clinical trial NCT04671303 (To Evaluate the Efficacy and Safety of …
Choline alfoscerate
A component of phosphatidylcholines (lecithins), in which the two hydroxy groups of glycerol are esterified with fatty acids. (From Stedman, 26th ed) It counteracts the effects of urea on enzymes and other macromolecules. [PubChem]
Experimental
Investigational
Matched Synonyms: … sn-3-GPC ... glycerol-3-phosphocholine ... sn-Glycero-3-phosphocholine …
Matched Description: … (From Stedman, 26th ed) It counteracts the effects of urea on enzymes and other macromolecules. …
Matched Products: … MEDOTİLİN 1000 MG/ 4 ML IM/IV ENJEKSİYONLUK ÇÖZELTİ İÇEREN AMPÜL, 3 ADET …
Matched Description: … (From Stedman, 26th ed) It counteracts the effects of urea on enzymes and other macromolecules. …
Matched Products: … MEDOTİLİN 1000 MG/ 4 ML IM/IV ENJEKSİYONLUK ÇÖZELTİ İÇEREN AMPÜL, 3 ADET …
Sodium ascorbate
Approved
Nutraceutical
Matched Synonyms: … Sodium ascorbate ... Vitamin C sodium ... sodium L-ascorbate …
Matched Name: … Sodium ascorbate …
Matched Iupac: … sodium (2R)-2-[(1S)-1,2-dihydroxyethyl]-4-hydroxy-5-oxo-2,5-dihydrofuran-3-olate …
Matched Mixtures name: … Peg-3350, Sodium Sulfate, Sodium Chloride, Potassium Chloride, Sodium Ascorbate and Ascorbic Acid ... PEG-3350, Electrolytes, and Ascorbate ... Bugs Bunny and Friends Multiple Vitamins …
Matched Categories: … Diet, Food, and Nutrition ... Vitamin C and analogues …
Matched Products: … Mega-C-sodium Inj 250mg/ml ... Sodium Ascor Crystal 888.8mg/gm USP ... ASCORBATO DE SODIO 112.49 MG/ML SOLUCION INYECTABLE …
Matched Name: … Sodium ascorbate …
Matched Iupac: … sodium (2R)-2-[(1S)-1,2-dihydroxyethyl]-4-hydroxy-5-oxo-2,5-dihydrofuran-3-olate …
Matched Mixtures name: … Peg-3350, Sodium Sulfate, Sodium Chloride, Potassium Chloride, Sodium Ascorbate and Ascorbic Acid ... PEG-3350, Electrolytes, and Ascorbate ... Bugs Bunny and Friends Multiple Vitamins …
Matched Categories: … Diet, Food, and Nutrition ... Vitamin C and analogues …
Matched Products: … Mega-C-sodium Inj 250mg/ml ... Sodium Ascor Crystal 888.8mg/gm USP ... ASCORBATO DE SODIO 112.49 MG/ML SOLUCION INYECTABLE …
Dextrothyroxine
The major hormone derived from the thyroid gland. Thyroxine is synthesized via the iodination of tyrosines (monoiodotyrosine) and the coupling of iodotyrosines (diiodotyrosine) in the thyroglobulin. Thyroxine is released from thyroglobulin by proteolysis and secreted into the blood. Thyroxine is peripherally deiodinated to form triiodothyronine which exerts a broad spectrum...
Approved
Investigational
Matched Synonyms: … O-(4-hydroxy-3,5-diiodophenyl)-3,5-diiodo-D-tyrosine …
Matched Iupac: … (2R)-2-amino-3-[4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl]propanoic acid …
Matched Description: … Thyroxine is synthesized via the iodination of tyrosines (monoiodotyrosine) and the coupling of iodotyrosines ... Thyroxine is released from thyroglobulin by proteolysis and secreted into the blood. …
Matched Salts name: … Dextrothyroxine sodium …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … Choloxin Tablet 4mg ... Choloxin - Tab 4mg …
Matched Iupac: … (2R)-2-amino-3-[4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl]propanoic acid …
Matched Description: … Thyroxine is synthesized via the iodination of tyrosines (monoiodotyrosine) and the coupling of iodotyrosines ... Thyroxine is released from thyroglobulin by proteolysis and secreted into the blood. …
Matched Salts name: … Dextrothyroxine sodium …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … Choloxin Tablet 4mg ... Choloxin - Tab 4mg …
Alendronic acid
Alendronic acid is a second generation bisphosphonate that is used for the treatment of some forms of osteoperosis and Paget's disease[FDA Label][A959,A203111]. It functions by preventing resorption of bone[FDA Label] .
Approved
Matched Synonyms: … (4-amino-1-hydroxybutane-1,1-diyl)bis(phosphonic acid) ... 4-amino-1-hydroxybutane-1,1-diphosphonic acid ... (4-amino-1-hydroxybutylidene)bisphosphonic acid …
Matched Iupac: … (4-amino-1-hydroxy-1-phosphonobutyl)phosphonic acid …
Matched Description: … is a second generation bisphosphonate that is used for the treatment of some forms of osteoperosis and …
Matched Salts cas: … 134606-40-9 ... 129318-43-0 …
Matched Mixtures name: … ALENDRON-HEXAL 4 WO CAL D ... BONYL PLUS ORAL ÇÖZELTI ,4 FLAKON ... VEGABON PLUS D TABLET, 4 ADET …
Matched Salts name: … Alendronate sodium ... Alendronate sodium anhydrous …
Matched Categories: … Drugs Affecting Bone Structure and Mineralization ... alendronic acid and colecalciferol ... alendronic acid and alfacalcidol, sequential ... alendronic acid, calcium and colecalciferol, sequential …
Matched Products: … LENDO 35 MG TABLET, 4 ADET ... ADROMAX 35 MG TABLET, 4 ADET ... Alendronate Sodium …
Matched Iupac: … (4-amino-1-hydroxy-1-phosphonobutyl)phosphonic acid …
Matched Description: … is a second generation bisphosphonate that is used for the treatment of some forms of osteoperosis and …
Matched Salts cas: … 134606-40-9 ... 129318-43-0 …
Matched Mixtures name: … ALENDRON-HEXAL 4 WO CAL D ... BONYL PLUS ORAL ÇÖZELTI ,4 FLAKON ... VEGABON PLUS D TABLET, 4 ADET …
Matched Salts name: … Alendronate sodium ... Alendronate sodium anhydrous …
Matched Categories: … Drugs Affecting Bone Structure and Mineralization ... alendronic acid and colecalciferol ... alendronic acid and alfacalcidol, sequential ... alendronic acid, calcium and colecalciferol, sequential …
Matched Products: … LENDO 35 MG TABLET, 4 ADET ... ADROMAX 35 MG TABLET, 4 ADET ... Alendronate Sodium …
IDN-7314
Investigational
Matched Synonyms: … (s)-3-((s)-2-(2-((2,6-difluorophenyl)amino)-2-oxoacetamido)propanamido)-4-oxo-5-(2,3,5,6-tetrafluorophenoxy ... N-(2,6-difluorophenyl)-2-oxoglycyl-n-((1s)-1-(carboxymethyl)-2-oxo-3-(2,3,5,6-tetrafluorophenoxy)propyl ... L-alaninamide, n-(2,6-difluorophenyl)-2-oxoglycyl-n-((1s)-1-(carboxymethyl)-2-oxo-3-(2,3,5,6-tetrafluorophenoxy …
Matched Iupac: … (3S)-3-[(2S)-2-{[(2,6-difluorophenyl)carbamoyl]formamido}propanamido]-4-oxo-5-(2,3,5,6-tetrafluorophenoxy …
Matched Iupac: … (3S)-3-[(2S)-2-{[(2,6-difluorophenyl)carbamoyl]formamido}propanamido]-4-oxo-5-(2,3,5,6-tetrafluorophenoxy …
Acenocoumarol
Acenocoumarol is a coumarin derivative used as an anticoagulant. Coumarin derivatives inhibit the reduction of vitamin K by vitamin K reductase. This prevents carboxylation of vitamin K-dependent clotting factors, II, VII, IX and X, and interferes with coagulation. Hematocrit, hemoglobin, international normalized ratio and liver panel should be monitored. Patients...
Approved
Investigational
Matched Synonyms: … 3-(alpha-Acetonyl-p-nitrobenzyl)-4-hydroxycoumarin ... 3-(alpha-(p-Nitrophenol)-beta-acetylethyl)-4-hydroxycoumarin ... 3-(alpha-p-Nitrophenyl-beta-acetylethyl)-4-hydroxycoumarin …
Matched Iupac: … 4-hydroxy-3-[1-(4-nitrophenyl)-3-oxobutyl]-2H-chromen-2-one …
Matched Description: … This prevents carboxylation of vitamin K-dependent clotting factors, II, VII, IX and X, and interferes ... [A188739] Hematocrit, hemoglobin, international normalized ratio and liver panel should be monitored. …
Matched Categories: … Blood and Blood Forming Organs ... Warfarin and isomers ... Cytochrome P-450 Substrates ... Cytochrome P-450 CYP1A2 Substrates ... Cytochrome P-450 CYP2C19 Substrates …
Matched Products: … Sintrom 4 mg Tabletten …
Matched Iupac: … 4-hydroxy-3-[1-(4-nitrophenyl)-3-oxobutyl]-2H-chromen-2-one …
Matched Description: … This prevents carboxylation of vitamin K-dependent clotting factors, II, VII, IX and X, and interferes ... [A188739] Hematocrit, hemoglobin, international normalized ratio and liver panel should be monitored. …
Matched Categories: … Blood and Blood Forming Organs ... Warfarin and isomers ... Cytochrome P-450 Substrates ... Cytochrome P-450 CYP1A2 Substrates ... Cytochrome P-450 CYP2C19 Substrates …
Matched Products: … Sintrom 4 mg Tabletten …
Iodohippurate sodium I-123
Approved
Matched Synonyms: … Sodium iodohippurate (123 I) ... sodium iodohippurate (123I) …
Matched Name: … Iodohippurate sodium I-123 …
Matched Iupac: … sodium 2-{[2-(¹²³I)iodophenyl]formamido}acetate …
Matched Categories: … sodium iodohippurate (123I) …
Matched Name: … Iodohippurate sodium I-123 …
Matched Iupac: … sodium 2-{[2-(¹²³I)iodophenyl]formamido}acetate …
Matched Categories: … sodium iodohippurate (123I) …
Penbutolol
Penbutolol is a drug in the beta-blocker class used to treat hypertension. Penbutolol binds both beta-1 and beta-2 adrenergic receptors, rendering it a non-selective beta-blocker. Penbutolol can act as a partial agonist at beta adrenergic receptors, since it is a sympathomimetric drug. Penbutolol also demonstrates high binding affinity to the...
Approved
Investigational
Matched Synonyms: … (2S)-1-(tert-butylamino)-3-(2-cyclopentylphenoxy)propan-2-ol …
Matched Iupac: … (2S)-1-(tert-butylamino)-3-(2-cyclopentylphenoxy)propan-2-ol …
Matched Description: … Penbutolol binds both beta-1 and beta-2 adrenergic receptors, rendering it a non-selective beta-blocker ... Penbutolol is contraindicated in patients with cardiogenic shock, sinus bradycardia, second and third ... degree atrioventricular conduction block, bronchial asthma, and those with known hypersensitivity. …
Matched Salts cas: … 38363-32-5 …
Matched Categories: … Cytochrome P-450 Substrates ... Cytochrome P-450 CYP2D6 Substrates ... penbutolol and other diuretics …
Matched Products: … BETAPRESSİN 40 MG FİLM TABLET, 30 TABLET …
Matched Iupac: … (2S)-1-(tert-butylamino)-3-(2-cyclopentylphenoxy)propan-2-ol …
Matched Description: … Penbutolol binds both beta-1 and beta-2 adrenergic receptors, rendering it a non-selective beta-blocker ... Penbutolol is contraindicated in patients with cardiogenic shock, sinus bradycardia, second and third ... degree atrioventricular conduction block, bronchial asthma, and those with known hypersensitivity. …
Matched Salts cas: … 38363-32-5 …
Matched Categories: … Cytochrome P-450 Substrates ... Cytochrome P-450 CYP2D6 Substrates ... penbutolol and other diuretics …
Matched Products: … BETAPRESSİN 40 MG FİLM TABLET, 30 TABLET …
N-Cyclohexyl-N'-phenyl-1,4-phenylenediamine
N-Cyclohexyl-N'-phenyl-1,4-phenylenediamine is a component of black rubber. It is also a dermatological sensitizer and allergen.
Sensitivity to N-Cyclohexyl-N'-phenyl-1,4-phenylenediamine may be identified with a clinical patch test.
Approved
Matched Synonyms: … N-Cyclohexyl-N'-phenyl-p-phenylendiamine ... N-cyclohexyl-N'-phenyl-p-phenylenediamine ... N-Cyclohexyl-N'-phenyl-1,4-phenylenediamine …
Matched Name: … N-Cyclohexyl-N'-phenyl-1,4-phenylenediamine …
Matched Description: … It is also a dermatological sensitizer and allergen. ... N-Cyclohexyl-N'-phenyl-1,4-phenylenediamine is a component of black rubber. ... Sensitivity to N-Cyclohexyl-N'-phenyl-1,4-phenylenediamine may be identified with a clinical patch test …
Matched Name: … N-Cyclohexyl-N'-phenyl-1,4-phenylenediamine …
Matched Description: … It is also a dermatological sensitizer and allergen. ... N-Cyclohexyl-N'-phenyl-1,4-phenylenediamine is a component of black rubber. ... Sensitivity to N-Cyclohexyl-N'-phenyl-1,4-phenylenediamine may be identified with a clinical patch test …
Bisoprolol
Bisoprolol is a cardioselective β1-adrenergic blocking agent used to treat high blood pressure.[A180472,L7219] It is considered a potent drug with a long-half life that can be used once daily to reduce the need for multiple doses of antihypertensive drugs. Bisoprolol is generally well tolerated, likely due to its β1-adrenergic receptor...
Approved
Matched Synonyms: … (RS)-1-(4-(2-Isopropoxyethoxymethyl)phenoxy)-3-(isopropylamino)-2-propanol ... (+-)-1-((alpha-(2-Isopropoxyethoxy)-p-tolyl)oxy)-3-(isopropylamino)-2-propanol …
Matched Iupac: … 1-[(propan-2-yl)amino]-3-(4-{[2-(propan-2-yloxy)ethoxy]methyl}phenoxy)propan-2-ol …
Matched Description: … A180472] Bisoprolol is generally well tolerated, likely due to its β1-adrenergic receptor selectivity and ... alternative to non-selective β-blocker drugs in the treatment of hypertension such as [Carvedilol] and ... It may be used alone or in combination with other drugs to manage hypertension[L7219] and can be useful …
Matched Mixtures name: … BISOPROLOL DURA P10/25MG ... BISOPROLOL DURA P10/25MG ... BISOPROLOL DURA P10/25MG …
Matched Categories: … Cytochrome P-450 Substrates ... Cytochrome P-450 CYP3A Substrates ... Cytochrome P-450 CYP3A4 Substrates ... Beta Blocking Agents and Thiazides ... P-glycoprotein inhibitors …
Matched Products: … PMS-bisoprolol ... PHL-bisoprolol ... Prz-bisoprolol …
Matched Iupac: … 1-[(propan-2-yl)amino]-3-(4-{[2-(propan-2-yloxy)ethoxy]methyl}phenoxy)propan-2-ol …
Matched Description: … A180472] Bisoprolol is generally well tolerated, likely due to its β1-adrenergic receptor selectivity and ... alternative to non-selective β-blocker drugs in the treatment of hypertension such as [Carvedilol] and ... It may be used alone or in combination with other drugs to manage hypertension[L7219] and can be useful …
Matched Mixtures name: … BISOPROLOL DURA P10/25MG ... BISOPROLOL DURA P10/25MG ... BISOPROLOL DURA P10/25MG …
Matched Categories: … Cytochrome P-450 Substrates ... Cytochrome P-450 CYP3A Substrates ... Cytochrome P-450 CYP3A4 Substrates ... Beta Blocking Agents and Thiazides ... P-glycoprotein inhibitors …
Matched Products: … PMS-bisoprolol ... PHL-bisoprolol ... Prz-bisoprolol …
Methylprednisolone
Methylprednisolone is a prednisolone derivative glucocorticoid with higher potency than prednisone. It was first described in the literature in the late 1950s.[A188811,A188814]
Methylprednisolone was granted FDA approval on 24 October 1957. In the outbreak of COVID-19, low dose methylprednisolone-based therapy was successful in treating COVID-19-associated pneumonia in one patient with...
Approved
Vet approved
Matched Iupac: … ,4H,5H,7H,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-7-one ... (1R,3aS,3bS,5S,9aR,9bS,10S,11aS)-1,10-dihydroxy-1-(2-hydroxyacetyl)-5,9a,11a-trimethyl-1H,2H,3H,3aH,3bH …
Matched Description: … methylprednisolone-based therapy was successful in treating COVID-19-associated pneumonia in one patient with long-term …
Matched Salts cas: … 53-36-1 …
Matched Mixtures name: … Dyural 40 Kit ... Dyural 40 Kit ... Methylprednisolone Sodium Succinate for Injection, USP …
Matched Categories: … Sex Hormones and Insulins ... methylprednisolone and antibiotics ... methylprednisolone and antiinfectives ... methylprednisolone and antiinfectives ... Ophthalmological and Otological Preparations …
Matched Products: … PREDNOL-L 40 MG LİYOFİLİZE ENJEKTABL AMPUL, 3 ADET ... METILPREDNISOLONA SODIO SUCCINATO. METIL PREDNISOLONA 500 MG. PARA RECONSTITUIR A 4 ML. ... Urbason solubile 32 mg Trockenampullen mit Lösungsmittel …
Matched Description: … methylprednisolone-based therapy was successful in treating COVID-19-associated pneumonia in one patient with long-term …
Matched Salts cas: … 53-36-1 …
Matched Mixtures name: … Dyural 40 Kit ... Dyural 40 Kit ... Methylprednisolone Sodium Succinate for Injection, USP …
Matched Categories: … Sex Hormones and Insulins ... methylprednisolone and antibiotics ... methylprednisolone and antiinfectives ... methylprednisolone and antiinfectives ... Ophthalmological and Otological Preparations …
Matched Products: … PREDNOL-L 40 MG LİYOFİLİZE ENJEKTABL AMPUL, 3 ADET ... METILPREDNISOLONA SODIO SUCCINATO. METIL PREDNISOLONA 500 MG. PARA RECONSTITUIR A 4 ML. ... Urbason solubile 32 mg Trockenampullen mit Lösungsmittel …
Edetate sodium
Experimental
Matched Synonyms: … EDTA sodium ... Edetate sodium ... Sodium edetate …
Matched Name: … Edetate sodium …
Matched Categories: … sodium edetate …
Matched Name: … Edetate sodium …
Matched Categories: … sodium edetate …
Entrectinib
Entrectinib is a tropomyosin receptor tyrosine kinase (TRK) TRKA, TRKB, TRKC, proto-oncogene tyrosine-protein kinase ROS1, and anaplastic lymphoma kinase (ALK) inhibitor. It was approved by the FDA in August 2019 for use in the treatment of ROS1-positive metastatic non-small cell lung cancer and NTRK gene fusion positive solid tumors. Entrectinib's...
Approved
Investigational
Matched Synonyms: … N-[5-[(3,5-difluorophenyl)methyl]-1H-indazol-3-yl]-4-(4-methylpiperazin-1-yl)-2-(oxan-4-ylamino)benzamide …
Matched Iupac: … N-{5-[(3,5-difluorophenyl)methyl]-1H-indazol-3-yl}-4-(4-methylpiperazin-1-yl)-2-[(oxan-4-yl)amino]benzamide …
Matched Description: … tropomyosin receptor tyrosine kinase (TRK) TRKA, TRKB, TRKC, proto-oncogene tyrosine-protein kinase ROS1, and ... FDA in August 2019 for use in the treatment of ROS1-positive metastatic non-small cell lung cancer and ... This therapy offers benefit over similar ALK inhibitors such as [alectinib], [ceritinib], and [lorlatinib …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Cytochrome P-450 Substrates ... Cytochrome P-450 CYP3A Substrates ... Cytochrome P-450 CYP3A4 Substrates ... Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index …
Matched Products: … ROZLYTREK 100 MG SERT KAPSÜL , 30 ADET …
Matched Iupac: … N-{5-[(3,5-difluorophenyl)methyl]-1H-indazol-3-yl}-4-(4-methylpiperazin-1-yl)-2-[(oxan-4-yl)amino]benzamide …
Matched Description: … tropomyosin receptor tyrosine kinase (TRK) TRKA, TRKB, TRKC, proto-oncogene tyrosine-protein kinase ROS1, and ... FDA in August 2019 for use in the treatment of ROS1-positive metastatic non-small cell lung cancer and ... This therapy offers benefit over similar ALK inhibitors such as [alectinib], [ceritinib], and [lorlatinib …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Cytochrome P-450 Substrates ... Cytochrome P-450 CYP3A Substrates ... Cytochrome P-450 CYP3A4 Substrates ... Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index …
Matched Products: … ROZLYTREK 100 MG SERT KAPSÜL , 30 ADET …
Estriol tripropionate
Experimental
Matched Synonyms: … Estriol propionate …
Matched Iupac: … (1R,2R,3aS,3bR,9bS,11aS)-11a-methyl-1,7-bis(propanoyloxy)-1H,2H,3H,3aH,3bH,4H,5H,9bH,10H,11H,11aH-cyclopenta ... [a]phenanthren-2-yl propanoate …
Matched Iupac: … (1R,2R,3aS,3bR,9bS,11aS)-11a-methyl-1,7-bis(propanoyloxy)-1H,2H,3H,3aH,3bH,4H,5H,9bH,10H,11H,11aH-cyclopenta ... [a]phenanthren-2-yl propanoate …
Imatinib
Imatinib is a small molecule kinase inhibitor that revolutionized the treatment of cancer, particularly chronic myeloid leukemia, in 2001. It was deemed a "miracle drug" due to its clinical success, as oncologist Dr. Brian noted that "complete hematologic responses were observed in 53 of 54 patients with CML treated with...
Approved
Matched Synonyms: … α-(4-methyl-1-piperazinyl)-3'-((4-(3-pyridyl)-2-pyrimidinyl)amino)-p-toluidide …
Matched Iupac: … N-(4-methyl-3-{[4-(pyridin-3-yl)pyrimidin-2-yl]amino}phenyl)-4-[(4-methylpiperazin-1-yl)methyl]benzamide …
Matched Description: … mg or more and typically occurred in the first four weeks of therapy". ... [L42220] Imatinib was approved on February 1st ,2001 by the FDA and November 7th, 2001 by the EMA ... complete hematologic responses were observed in 53 of 54 patients with CML treated with a daily dosage of 300 …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Benzamides and benzamide derivatives ... Cytochrome P-450 Substrates ... Cytochrome P-450 CYP1A2 Substrates ... Cytochrome P-450 CYP2C8 Substrates …
Matched Products: … PMS-imatinib ... IMANIVEC 100MG DISP TBL ... IMANIVEC 400MG DISP TBL …
Matched Iupac: … N-(4-methyl-3-{[4-(pyridin-3-yl)pyrimidin-2-yl]amino}phenyl)-4-[(4-methylpiperazin-1-yl)methyl]benzamide …
Matched Description: … mg or more and typically occurred in the first four weeks of therapy". ... [L42220] Imatinib was approved on February 1st ,2001 by the FDA and November 7th, 2001 by the EMA ... complete hematologic responses were observed in 53 of 54 patients with CML treated with a daily dosage of 300 …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Benzamides and benzamide derivatives ... Cytochrome P-450 Substrates ... Cytochrome P-450 CYP1A2 Substrates ... Cytochrome P-450 CYP2C8 Substrates …
Matched Products: … PMS-imatinib ... IMANIVEC 100MG DISP TBL ... IMANIVEC 400MG DISP TBL …
Futibatinib
Futibatinib is an inhibitor of Fibroblast Growth Factor receptor (FGFR), which comprises a group of receptor tyrosine kinases that play a key role in cell proliferation, differentiation, migration, and survival. FGFR was investigated in oncology as a therapeutic target, as FGFR genomic aberrations and dysregulated FGFR signalling pathways are observed...
Approved
Investigational
Matched Synonyms: … 1-((3S)-(4-amino-3-((3,5-dimethoxyphenyl)ethynyl)-1H-pyrazolo(3, 4-d) pyrimidin-1-yl)-1-pyrrolidinyl) ... 1-[(3S)-3-{4-amino-3-[(3,5-dimethoxyphenyl)ethynyl]-1H-pyrazolo[3,4-d]pyrimidin-1-yl}pyrrolidin-1-yl] …
Matched Iupac: … 1-[(3S)-3-{4-amino-3-[2-(3,5-dimethoxyphenyl)ethynyl]-1H-pyrazolo[3,4-d]pyrimidin-1-yl}pyrrolidin-1-yl …
Matched Description: … of receptor tyrosine kinases that play a key role in cell proliferation, differentiation, migration, and ... FGFR was investigated in oncology as a therapeutic target, as FGFR genomic aberrations and dysregulated ... FGFR signalling pathways are observed in some cancers such as cholangiocarcinoma and urothelial malignancies …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Cytochrome P-450 Substrates ... Cytochrome P-450 CYP2C9 Substrates ... Cytochrome P-450 CYP3A Substrates ... Cytochrome P-450 CYP2D6 Substrates …
Matched Iupac: … 1-[(3S)-3-{4-amino-3-[2-(3,5-dimethoxyphenyl)ethynyl]-1H-pyrazolo[3,4-d]pyrimidin-1-yl}pyrrolidin-1-yl …
Matched Description: … of receptor tyrosine kinases that play a key role in cell proliferation, differentiation, migration, and ... FGFR was investigated in oncology as a therapeutic target, as FGFR genomic aberrations and dysregulated ... FGFR signalling pathways are observed in some cancers such as cholangiocarcinoma and urothelial malignancies …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Cytochrome P-450 Substrates ... Cytochrome P-450 CYP2C9 Substrates ... Cytochrome P-450 CYP3A Substrates ... Cytochrome P-450 CYP2D6 Substrates …
DMP-777
DMP-777 is a selective inhibitor of polymorphonuclear leukocyte (PMN) elastase.
Investigational
Matched Synonyms: … 1-AZETIDINECARBOXAMIDE, N-((1R)-1-(1,3-BENZODIOXOL-5-YL)BUTYL)-3,3-DIETHYL-2-(4-((4-METHYL-1-PIPERAZINYL ... )CARBONYL)PHENOXY)-4-OXO-, (2S)- …
Matched Iupac: … (2S)-N-[(1R)-1-(2H-1,3-benzodioxol-5-yl)butyl]-3,3-diethyl-2-[4-(4-methylpiperazine-1-carbonyl)phenoxy ... ]-4-oxoazetidine-1-carboxamide …
Matched Description: … DMP-777 is a selective inhibitor of polymorphonuclear leukocyte (PMN) elastase. …
Matched Iupac: … (2S)-N-[(1R)-1-(2H-1,3-benzodioxol-5-yl)butyl]-3,3-diethyl-2-[4-(4-methylpiperazine-1-carbonyl)phenoxy ... ]-4-oxoazetidine-1-carboxamide …
Matched Description: … DMP-777 is a selective inhibitor of polymorphonuclear leukocyte (PMN) elastase. …
Sodium aluminosilicate
Experimental
Matched Synonyms: … Aluminum sodium silicate ... Sodium silicoaluminate ... Sodium aluminum silicate …
Matched Name: … Sodium aluminosilicate …
Matched Name: … Sodium aluminosilicate …
Displaying drugs 751 - 775 of 5715 in total