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Pravastatin is the 6-alpha-hydroxy acid form of mevastatin. Pravastatin was firstly approved in 1991 becoming the second available statin in the United States. It was the first statin administered as the active form and not as a prodrug. This drug was developed by Sankyo Co. Ltd.; however, the first approved...
Approved
Matched Synonyms: … (+)-(3R,5R)-3,5-dihydroxy-7-[(1S,2S,6S,8S,8aR)-6-hydroxy-2-methyl-8-{[(S)-2-methylbutyryl]oxy}-1,2,6,7,8,8a-hexahydro …
Matched Iupac: … (3R,5R)-7-[(1S,2S,6S,8S,8aR)-6-hydroxy-2-methyl-8-{[(2S)-2-methylbutanoyl]oxy}-1,2,6,7,8,8a-hexahydronaphthalen …
Matched Description: … It was the first statin administered as the active form and not as a prodrug. ... Ltd.; however, the first approved pravastatin product was developed by Bristol Myers Squibb and FDA approved ... The manufacturing process is followed by the hydrolysis of the lactone group and the biological hydroxylation …
Matched Salts name: … Pravastatin sodium
Matched Categories: … pravastatin and ezetimibe ... pravastatin and fenofibrate ... pravastatin and acetylsalicylic acid ... pravastatin, ezetimibe and fenofibrate …
Matched Products: … PRAVASTATINA DOC ... Dom-pravastatin ... Pravastatin Sodium
Experimental
Matched Synonyms: … β-D-Fuc ... β-D-fucose …
Matched Name: … beta-D-fucose …
Matched Iupac: … (2R,3R,4S,5R,6R)-6-methyloxane-2,3,4,5-tetrol …
An unnatural amino acid that is used experimentally to study protein structure and function. It is structurally similar to METHIONINE, however it does not contain SULFUR.
Experimental
Matched Synonyms: … D-(−)-norleucine ... D-2-aminohexanoic acid …
Matched Name: … D-norleucine …
Matched Description: … An unnatural amino acid that is used experimentally to study protein structure and function. …
The D-enantiomer of alanine.
Experimental
Matched Synonyms: … DAL ... D-Ala ... D-Alanin …
Matched Name: … D-Alanine …
Matched Description: … The D-enantiomer of alanine. …
Nortriptyline hydrochloride, the active metabolite of amitriptyline, is a tricyclic antidepressant (TCA). It is used in the treatment of major depression and is also used off-label for chronic pain and other conditions.
Approved
Matched Synonyms: … 3-(10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5-ylidene)-N-methyl-1-propanamine ... 10,11-dihydro-N-methyl-5H-dibenzo[a,d]cycloheptene-Δ5,γ-propylamine …
Matched Description: … and other conditions. ... [L11878] It is used in the treatment of major depression and is also used off-label for chronic pain …
Matched Categories: … Tricyclics and Other Norepinephrine-reuptake Inhibitors ... Dopamine D2 Receptor Antagonists ... Serotonin 5-HT1 Receptor Antagonists ... Serotonin 5-HT2 Receptor Antagonists ... Serotonin 5-HT1A Receptor Antagonists …
Matched Products: … CIFLOXAL® 500 MG TABLETAS RECUBIERTAS ... Dom-nortriptyline 10mg Capsules ... Dom-nortriptyline 25mg Capsules …
A non-metabolizable galactose analog that induces expression of the LAC operon.
Experimental
Matched Synonyms: … isopropyl β-D-thiogalactoside ... isopropyl-β-D-thiogalactoside ... isopropyl β-D-thiogalactopyranoside …
Matched Name: … Isopropyl beta-D-thiogalactopyranoside …
Matched Iupac: … (2R,3R,4S,5R,6S)-2-(hydroxymethyl)-6-(propan-2-ylsulfanyl)oxane-3,4,5-triol …
Hydroxyethyl starch (HES/HAES) is a nonionic starch derivative. Hydroxyethyl starches (HES) are synthetic colloids commonly used for fluid resuscitation to replace intravascular volume. HES is a general term and can be sub-classified according to average molecular weight, molar substitution, concentration, C2/C6 ratio and Maximum Daily Dose.
Approved
Matched Description: … , concentration, C2/C6 ratio and Maximum Daily Dose. ... HES is a general term and can be sub-classified according to average molecular weight, molar substitution …
Matched Mixtures name: … NEOHES %6 HES % 0.9 SODYUM KLORÜR İV İNFÜZYON İÇİN ÇÖZELTİ, 500 ML SETLİ ... NEOHES %6 HES % 0.9 SODYUM KLORÜR İV İNFÜZYON İÇİN ÇÖZELTİ, 500 ML SETSİZ ... Hydroxyethyl Starch in Sodium Chloride …
Matched Categories: … Blood and Blood Forming Organs ... Blood and Related Products ... Blood Substitutes and Perfusion Solutions ... Blood Substitutes and Plasma Protein Fractions …
Matched Products: … Hetastarch in Sodium Chloride ... 6% Hetastarch In 0.9% Sodium Chloride ... VARIHES %6 500 ML(SETLI) …
Experimental
Matched Synonyms: … Dodecyl D-glucoside ... Dodecyl D-glucopyranoside …
Matched Iupac: … (3R,4S,5S,6R)-2-(dodecyloxy)-6-(hydroxymethyl)oxane-3,4,5-triol …
1-Deoxy-D-xylulose 5-phosphate is a solid. This compound belongs to the pentose phosphates. These are carbohydrate derivatives containing a pentose substituted by one or more phosphate groups. The proteins that 1-Deoxy-D-xylulose 5-phosphate targets include 1-Deoxy-D-xylulose 5-phosphate reductoisomerase and pyridoxine 5'-phosphate synthase. 1-Deoxy-D-xylulose 5-phosphate is an intermediate in the non-mevalonate pathway.
Experimental
Matched Name: … 1-Deoxy-D-xylulose 5-phosphate …
Matched Description: … and pyridoxine 5'-phosphate synthase. 1-Deoxy-D-xylulose 5-phosphate is an intermediate in the non-mevalonate ... The proteins that 1-Deoxy-D-xylulose 5-phosphate targets include 1-Deoxy-D-xylulose 5-phosphate reductoisomerase ... 1-Deoxy-D-xylulose 5-phosphate is a solid. This compound belongs to the pentose phosphates. …
Experimental
Matched Name: … Thymidine-5'-diphospho-beta-D-xylose …
Matched Iupac: … {[hydroxy({[(2R,3R,4S,5R)-3,4,5-trihydroxyoxan-2-yl]oxy})phosphoryl]oxy}({[(2R,3S,5R)-3-hydroxy-5-(5- …
The α-anomer of D-galacturonic acid.
Experimental
Matched Synonyms: … α-D-galacturonic acid ... α-D-galactopyranuronic acid ... alpha-D-galactopyranuronic acid …
Matched Name: … alpha-D-galacturonic acid …
Matched Iupac: … (2S,3R,4S,5R,6S)-3,4,5,6-tetrahydroxyoxane-2-carboxylic acid …
Matched Description: … The α-anomer of D-galacturonic acid. …
Colistimethate is an antibiotic that has been shown to have bactericidal activity against aerobic gram-negative microorganisms. Colistimethate is particularly indicated when the infection is caused by sensitive strains of Pseudomonas aeruginosa.
Approved
Vet approved
Matched Salts name: … Colistimethate sodium
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Products: … COLISTIMETATO DE SODIO ... COLISTIMETATO DE SODIO 2 MUI ... Colistimethate Sodium
Approved
Matched Synonyms: … 1,2-dipalmitoyl-sn-glycero-3-phosphorylglycerol sodium salt …
Matched Name: … Sodium 1,2-Dipalmitoyl-sn-glycero-3-phospho-(1'-rac-glycerol) …
Matched Iupac: … sodium (2R)-1-[(2,3-dihydroxypropyl phosphono)oxy]-3-(hexadecanoyloxy)propan-2-yl hexadecanoate …
Alpha-tocopherol is the primary form of vitamin E that is preferentially used by the human body to meet appropriate dietary requirements. In particular, the RRR-alpha-tocopherol (or sometimes called the d-alpha-tocopherol stereoisomer) stereoisomer is considered the natural formation of alpha-tocopherol and generally exhibits the greatest bioavailability out of all of the...
Approved
Nutraceutical
Vet approved
Matched Synonyms: … Vitamin E acetate, D- ... D-alpha tocoferil acetate ... alpha-tocopheryl acetate, D- …
Matched Name: … D-alpha-Tocopherol acetate …
Matched Description: … is considered the natural formation of alpha-tocopherol and generally exhibits the greatest bioavailability ... At the moment however, there exists a lack of formal data and evidence to support any such additional ... This biologic action of vitamin E consequently continues to generate ongoing interest and study in whether …
Matched Mixtures name: … IQQU Advanced Sunscreen SPF 50 ... Multi Vitamin and Mineral vitamin ... Iron With Vitamins C and E - Tab …
Matched Categories: … Diet, Food, and Nutrition …
Ritlecitinib (PF-06651600) is a highly selective inhibitor of Janus kinase 3 (JAK3) and the tyrosine kinase expressed in hepatocellular carcinoma (TEC) kinase family. In June 2023, it was approved by the FDA for the treatment of severe alopecia areata in adults and adolescents 12 years and older.[L47092,L47127] It was further...
Approved
Investigational
Matched Synonyms: … 2-propen-1-one, 1-((2S,5R)-2-methyl-5-(7H-pyrrolo(2,3-D)pyrimidin-4-ylamino)-1-piperidinyl)- …
Matched Iupac: … 1-[(2S,5R)-2-methyl-5-({7H-pyrrolo[2,3-d]pyrimidin-4-yl}amino)piperidin-1-yl]prop-2-en-1-one …
Matched Description: … 12 years and older. ... This makes ritlecitinib a highly selective and irreversible JAK3 inhibitor. ... Ritlecitinib (PF-06651600) is a highly selective inhibitor of Janus kinase 3 (JAK3) and the tyrosine …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Phloxine B (commonly known simply as phloxine, also known as D&C RED NO. 28) is a color additive which is used both as an inactive ingredient to provide color to products, or as a colorant in dental disclosing tablets. These tablets allow patients to visualise areas where more brushing and...
Approved
Matched Synonyms: … D&C Red No. 28 ... Disodium 2',4',5',7'-tetrabromo-4,5,6,7-tetrachlorofluorescein …
Matched Description: … These tablets allow patients to visualise areas where more brushing and flossing are needed. ... Phloxine B (commonly known simply as phloxine, also known as D&C RED NO. 28) is a color additive which …
Matched Categories: … Indicators and Reagents …
Matched Products: … Disclose Dry Handle Swab …
A semisynthetic cephalosporin analog with broad-spectrum antibiotic action due to inhibition of bacterial cell wall synthesis. It attains high serum levels and is excreted quickly via the urine.
Approved
Matched Synonyms: … 5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid ... (6R,7R)-3-{[(5-methyl-1,3,4-thiadiazol-2-yl)sulfanyl]methyl}-8-oxo-7-[(1H-tetrazol-1-ylacetyl)amino]- …
Matched Iupac: … ]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid ... (6R,7R)-3-{[(5-methyl-1,3,4-thiadiazol-2-yl)sulfanyl]methyl}-8-oxo-7-[2-(1H-1,2,3,4-tetrazol-1-yl)acetamido …
Matched Description: … It attains high serum levels and is excreted quickly via the urine. ... A semisynthetic cephalosporin analog with broad-spectrum antibiotic action due to inhibition of bacterial …
Matched Mixtures name: … CEFAMEZIN 500 MG IM ENJEKTABL TOZ İÇEREN FLAKON, 1 ADET …
Matched Salts name: … Cefazolin sodium
Matched Products: … Cefazolin Sodium ... CEFAZOLIN SODIUM ... CEFAZOLINA SODICO 1 G …
The N-acetyl derivative of glucosamine.
Approved
Investigational
Nutraceutical
Matched Synonyms: … D-GlcNAc ... N-Acetyl-D-glucosamine ... 2-Acetamido-2-deoxy-D-glucose …
Matched Iupac: … N-[(2R,3R,4S,5R)-3,4,5,6-tetrahydroxy-1-oxohexan-2-yl]acetamide …
Sulbactam is a beta (β)-lactamase inhibitor and a derivative of the basic penicillin nucleus. When given in combination with β-lactam antibiotics, sulbactam produces a synergistic effect as it blocks the enzyme responsible for drug resistance by hydrolyzing β-lactams.
Approved
Matched Synonyms: … (2S,5R)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid 4,4-dioxide ... (2S,5R)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid 4,4-dioxide …
Matched Iupac: … (2S,5R)-3,3-dimethyl-4,4,7-trioxo-4lambda6-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid …
Matched Description: … Sulbactam is a beta (β)-lactamase inhibitor and a derivative of the basic penicillin nucleus. …
Matched Mixtures name: … SULAMP® DUO TABLETA RECUBIERTA ... Ampicillin Sodium and Sulbactam Sodium ... Ampicillin Sodium and Sulbactam Sodium
Matched Salts name: … Sulbactam sodium
Matched Products: … PENTICLOX-DUO ... SULFACETAMIDA SODICA TOR 30% GOTAS OFTALMICAS ... MAXTAM INJECTION 500 MG. …
Investigational
Matched Synonyms: … -d-ribofuranosyl)-5'-c-((2s)-5-(((4-butylphenyl)amino)carbonyl)-2,3,4,7-tetrahydro-1,4-dimethyl-3-oxo ... Uridine, 5'-o-(5-amino-5-deoxy-.beta. ... 5-{[(5-amino-3,3-dihydroxyoxolan-2-yl)oxy][5-(2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)-3,4-dihydroxyoxolan …
Matched Iupac: … (2S)-2-[(S)-{[(2S,3R,4S,5R)-5-(aminomethyl)-3,4-dihydroxyoxolan-2-yl]oxy}[(2S,3S,4R,5R)-5-(2,4-dioxo- ... dihydroxyoxolan-2-yl]methyl]-N-(4-butylphenyl)-1,4-dimethyl-3-oxo-2,3,4,7-tetrahydro-1H-1,4-diazepine-5- …
Experimental
Matched Synonyms: … β-D-GlcNAc-(1→4)-β-D-GlcNAc ... β-D-GlcpNAc-(1→4)-β-D-GlcpNAc …
Matched Name: … N-acetyl-beta-D-glucosaminyl-(1->4)-N-acetyl-beta-D-glucosamine …
Matched Iupac: … N-[(2S,3R,4R,5S,6R)-2-{[(2R,3S,4R,5R,6R)-5-acetamido-4,6-dihydroxy-2-(hydroxymethyl)oxan-3-yl]oxy}-4,5 …
Experimental
Matched Synonyms: … 1-Heptyl beta-D-glucoside ... n-Heptyl beta-D-glucoside ... Heptyl beta-D-glucopyranoside …
Matched Iupac: … (2R,3R,4S,5S,6R)-2-(heptyloxy)-6-(hydroxymethyl)oxane-3,4,5-triol …
Ibandronate, or BM 21.0955, is a third generation, nitrogen containing bisphosphonate similar to zoledronic acid, minodronic acid, and risedronic acid.[A203111,A203138] It is used to prevent and treat postmenopausal osteoporosis.[L13805,L13808] Ibandronate was first described in the literature in 1993 as a treatment for bone loss in dogs. Ibandronate was granted FDA...
Approved
Investigational
Matched Description: … [A203111,A203138] It is used to prevent and treat postmenopausal osteoporosis. ... third generation, nitrogen containing bisphosphonate similar to [zoledronic acid], [minodronic acid], and
Matched Mixtures name: … IBONE D® ... IBONE D 30000 ... IBONE D 30000 …
Matched Salts name: … Ibandronate sodium
Matched Categories: … ibandronic acid and colecalciferol ... Drugs Affecting Bone Structure and Mineralization …
Matched Products: … Ibandronate Sodium ... Ibandronate sodium ... ASCENDRA 3MG DUO D3 1 + 90 …
Experimental
Matched Synonyms: … 4,6-Dideoxy-4-{[(1s,5r,6s)-3-formyl-5,6-dihydroxy-4-oxocyclohex-2-en-1-yl]amino}-alpha-d-xylo-hex-5-enopyranose ... 1,4-Deoxy-4-((5-Hydroxymethyl-2,3,4-Trihydroxycyclohex-5-Enyl)Amino)Fructose …
Matched Name: … 4,6-Dideoxy-4-{[(1S,5R,6S)-3-formyl-5,6-dihydroxy-4-oxo-2-cyclohexen-1-yl]amino}-α-D-xylo-hex-5-enopyranose …
Matched Iupac: … (3S,4S,5R)-4,5-dihydroxy-6-oxo-3-{[(3S,4S,5R,6S)-4,5,6-trihydroxy-2-methylideneoxan-3-yl]amino}cyclohex …
Experimental
Matched Synonyms: … β-D-galacturonic acid ... β-D-Galactopyranuronic acid …
Matched Name: … beta-D-Galactopyranuronic acid …
Matched Iupac: … (2S,3R,4S,5R,6R)-3,4,5,6-tetrahydroxyoxane-2-carboxylic acid …
Displaying drugs 751 - 775 of 3679 in total