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Displaying drugs 751 - 775 of 1025 in total
Investigational
Matched Name: … Recombinant human palmitoyl protein thioesterase-1 …
INVAC-1 is under investigation in clinical trial NCT03265717 (DNA Plasmid Encoding a Modified Human Telomerase Reverse Transcriptase (Htert), Invac-1 in Chronic Lymphocytic Leukemia).
Investigational
Matched Synonyms: … Human telomerase reverse transcriptase (htert) dna vaccine invac-1 ... Invac-1, a double stranded dna plasmid vaccine construct encoding ubiquitin-human telomerase reverse …
Matched Description: … INVAC-1 is under investigation in clinical trial NCT03265717 (DNA Plasmid Encoding a Modified Human Telomerase …
Investigational
Matched Synonyms: … Adeno-associated viral vector serotype 8 containing the human RPGR gene ... Adenovirus-associated viral vector serotype 8 containing the human RPGR gene …
Efruxifermin is under investigation in clinical trial NCT06215716 (A Study Evaluating Efruxifermin in Subjects With Non-cirrhotic Nonalcoholic Steatohepatitis (Nash)/metabolic Dysfunction-associated Steatohepatitis (MASH) and Fibrosis).
Investigational
Matched Synonyms: … factor 21 (98-arginine,171-glycine,180-glutamic acid) (human mutant clone amg876) ... Immunoglobulin g (synthetic human constant domain fc fragment) fusion protein with fibroblast growth ... Immunoglobulin g1 (human .gamma.1-chain c-region c-terminal fragment) fusion protein with peptide linker …
Matched Description: … Non-cirrhotic Nonalcoholic Steatohepatitis (Nash)/metabolic Dysfunction-associated Steatohepatitis (MASH) and
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins …
A nitrogen mustard alkylating agent used as antineoplastic agent for the treatment of various malignant and nonmalignant diseases. Although it is less toxic than most other nitrogen mustards, it has been listed as a known carcinogen in the Fourth Annual Report on Carcinogens (NTP 85-002, 1985). (Merck Index, 11th ed)
Approved
Matched Description: … nitrogen mustard alkylating agent used as antineoplastic agent for the treatment of various malignant and
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … LEUKERAN TABLET 2 mg (Revised Formula) …
Investigational
Matched Synonyms: … Human recombinant histidyl-t-RNA synthetase (residues 2-506) …
Timolol is a nonselective beta-adrenergic antagonist given in an eye drop solution to reduce intraocular pressure, or pressure in the eyes. It is also used in tablet form as a drug to treat hypertension. Timolol was first approved by the FDA in 1978. This drug is marketed by several manufacturers...
Approved
Matched Description: … of conditions such as open-angle glaucoma and hypertension. ... [L6724] This drug is marketed by several manufacturers [L6736] and is an effective agent for the management …
Matched Mixtures name: … Dorzolamide and Timolol ... Dorzolamide and Timolol ... Dorzolamide Hydrochloride and Timolol Maleate …
Matched Categories: … timolol and thiazides ... Beta Blocking Agents and Thiazides ... Antiglaucoma Preparations and Miotics ... timolol, thiazides and other diuretics ... Beta Blocking Agents, Non-Selective, and Thiazides …
Matched Products: … Timolol Maleate Ophthalmic Gel Forming Solution, 0.25% ... Timolol Maleate Ophthalmic Gel Forming Solution, 0.5% ... Timolol Maleate Ophthalmic Gel Forming Solution …
Investigational
Matched Synonyms: … Adeno-associated viral vector serotype 8 containing the human glucose-6-phosphatase gene ... Recombinant adeno-associated virus serotype 8 vector encoding human glucose-6-phosphatase-alpha ... Recombinant adeno-associated virus serotype 8 vector encoding human glucose-6-phosphatase-alpha (G6Pase …
Investigational
Matched Synonyms: … IMMUNOGLOBULIN G1, ANTI-(HUMAN B7 HOMOLOG 3 PROTEIN) (HUMAN-MUS MUSCULUS MONOCLONAL MABX-9001A .GAMMA ... .1-CHAIN), DISULFIDE WITH HUMAN-MUS MUSCULUS MONOCLONAL MABX-9001A .KAPPA. …
Insulin detemir is a long-acting form of insulin used for the treatment of hyperglycemia caused by Type 1 and Type 2 Diabetes.[A2358, A2359, A2360, A44] Insulin is typically prescribed for the management of diabetes mellitus to mimic the activity of endogenously produced human insulin, a peptide hormone produced by beta...
Approved
Matched Synonyms: … Insulin,detemir,human
Matched Description: … typically prescribed for the management of diabetes mellitus to mimic the activity of endogenously produced human ... [A2358, A2359, A2360, A44] This insulin analogue has a 14-C fatty acid, myristic acid, bound to the lysine ... tissues such as the liver, fat cells, and skeletal muscle. …
Matched Categories: … Alimentary Tract and Metabolism ... Amino Acids, Peptides, and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Carlumab has been used in trials studying the treatment of Cancer and Prostate Cancer.
Investigational
Withdrawn
Matched Synonyms: … Human monoclonal antibody targeting CC-chemokine ligand 2 (CNTO 888) …
Matched Description: … Carlumab has been used in trials studying the treatment of Cancer and Prostate Cancer. …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Investigational
Matched Synonyms: … Synthetic Signal Peptide Of Human Mucin-1 (Amino Acids 1-21) …
HMI-102 is an investigational gene therapy designed to encode the phenylalanine-4-hydroxylase (PAH) gene, mutated in people with phenylketonuria.
Investigational
Matched Synonyms: … Recombinant adeno-associated viral vector serotype HSC expressing human phenylalanine hydroxylase …
Investigational
Matched Synonyms: … Expanded human allogeneic neural retinal progenitor cells extracted from neural retina …
Matched Name: … Expanded human allogeneic neural retinal progenitor cells extracted from neural retina …
Pemtumomab is a murine monoclonal antibody radiolabeled with Yttrium-90. It targets the mucin 1 (MUC1) protein.
Investigational
Matched Synonyms: … Murine MAb to polymorphic epithelial mucin, human milk fat globule 1 …
Matched Categories: … Amino Acids, Peptides, and Proteins …
BGT-DTDS is an investigational gene therapy comprising an adeno-associated viral vector type 2 (AAV2) encoding the human SLC6A3 gene. It is under investigation for the treatment of dopamine transporter deficiency syndrome (DTDS).
Investigational
Matched Synonyms: … Adeno-associated viral vector serotype 2 containing the human SLC6A3 gene …
Matched Description: … investigational gene therapy comprising an adeno-associated viral vector type 2 (AAV2) encoding the human
Amatuximab has been used in trials studying the treatment and basic science of Mesothelioma, Ovarian Cancer, Ovarian Neoplasms, Pancreatic Cancer, and Mesothelioma, Malignant, among others.
Investigational
Matched Synonyms: … Immunoglobulin G1, anti-(mesothelin) (human-mouse monoclonal MORAb-009 heavy chain), disulfide with human-mouse …
Matched Description: … Cancer, Ovarian Neoplasms, Pancreatic Cancer, and Mesothelioma, Malignant, among others. ... Amatuximab has been used in trials studying the treatment and basic science of Mesothelioma, Ovarian …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Dapiclermin is a recombinant ciliary neurotrophic factor.
Investigational
Matched Synonyms: … 2-185-ciliary neurotrophic factor (17 -alanine,63-arginine) (human isoform axokine) ... 2-185-(17-alanine,63-agrinine)ciliary neurotrophic factor-(2,185)-peptide (human isoform axokine) …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins …
Investigational
Matched Synonyms: … IMMUNOGLOBULIN G1, ANTI-(CYTOMEGALOVIRUS) (HUMAN MONOCLONAL EV2-7 .GAMMA.1-CHAIN), DISULFIDE WITH HUMAN
Matched Categories: … Amino Acids, Peptides, and Proteins …
Investigational
Matched Synonyms: … SDF-1 (108) Lysine Dlmer …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Investigational
Matched Synonyms: … with human-mus musculus monoclonal c4g7 .kappa. ... Immunoglobulin g1, anti-(ebolavirus glycoprotein) (human-mus musculus monoclonal c4g7 heavy chain), disulfide …
AAV9/MFSD8 is a gene therapy developed by Neurogene Inc. It is an adeno-associated virus serotype 9 (AAV9) vector with an engineered transgene encoding the human CLN7/MFSD8 gene for expression of active human major facilitator superfamily domain containing 8. It was investigated for the treatment of neuronal ceroid lipofuscinosis type 7.
Investigational
Matched Synonyms: … MFSD8 gene for expression of active human major facilitator superfamily domain containing 8 ... An adeno-associated virus serotype 9 (AAV9) vector with engineered transgene encoding the human CLN7/ …
Matched Description: … CLN7/MFSD8 gene for expression of active human major facilitator superfamily domain containing 8. ... It is an adeno-associated virus serotype 9 (AAV9) vector with an engineered transgene encoding the human
Sotatercept is an activin signalling inhibitor. It is a homodimeric recombinant fusion protein consisting of the extracellular domain of the human activin receptor type IIA (ActRIIA) linked to the human IgG1 Fc domain. On March 26, 2024, sotatercept was approved by the FDA for the treatment of pulmonary arterial hypertension...
Approved
Investigational
Matched Synonyms: … (HUMAN ACTIVIN RECEPTOR TYPE-2A PRECURSOR-(21-135)-PEPTIDYL)-THREONYLTRIGLYCYL-(HUMAN IMMUNOGLOBULIN ... (HUMAN ACTIVIN RECEPTOR TYPE-2A PRECURSOR-(21-135)-PEPTIDYL)-THREONYLTRIGLYCYL-(HUMAN IMMUNOGLOBULIN ... IMMUNOGLOBULIN G1 (SYNTHETIC HUMAN HEAVY CHAIN FC FRAGMENT), DIMER …
Matched Description: … [L50361] Sotatercept works to resolve the imbalance in activin–growth differentiation factor and BMP ... receptor type IIA (ActRIIA) linked to the human IgG1 Fc domain. ... It is a homodimeric recombinant fusion protein consisting of the extracellular domain of the human activin …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Ripertamab is under investigation in clinical trial NCT02772822 (A Study Comparing the Efficiency and Safety of S-chop(cyclophosphamide, Hydroxydaunomycin, Oncovin, and Prednisone) Versus R-CHOP in Untreated Cd20(cluster of Differentiation Antigen 20)-positive DLBCL Patients).
Investigational
Matched Synonyms: … Immunoglobulin igg1, anti-(human cd20 antigen) (human-mus musculus monoclonal disulfide sct400 .gamma ... .1-chain), disulfide with human-mus musculus monoclonal sct400 .kappa. …
Matched Description: … Ripertamab is under investigation in clinical trial NCT02772822 (A Study Comparing the Efficiency and ... Safety of S-chop(cyclophosphamide, Hydroxydaunomycin, Oncovin, and Prednisone) Versus R-CHOP in Untreated …
Investigational
Matched Synonyms: … Immunoglobulin g4 (224-proline,233-alanine,234-alanine), anti-(human dickkopf-1) (human-mus musculus ... monoclonal dkn-01 .gamma.4-chain), disulfide with human-mus musculus monoclonal dkn-01 .kappa. …
Displaying drugs 751 - 775 of 1025 in total