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Displaying drugs 751 - 775 of 4286 in total
Experimental
Matched Name: … D-Threonine
Matched Iupac: … (2R,3R)-2-amino-3-hydroxybutanoic acid
Experimental
Matched Synonyms: … 2-(N-morpholino)ethanesulfonic acid ... 2-(4-morpholinyl)ethanesulfonic acid ... 2-morpholinoethanesulphonic acid
Matched Name: … 2-(N-morpholino)ethanesulfonic acid
Matched Categories: … Sulfur Acids ... Sulfonic Acids
An N-acyl derivative of neuraminic acid. N-acetylneuraminic acid occurs in many polysaccharides, glycoproteins, and glycolipids in animals and bacteria. (From Dorland, 28th ed, p1518)
Experimental
Matched Synonyms: … N-Acetyl-alpha-D-neuraminic acid ... O-sialic acid
Matched Name: … N-acetyl-alpha-neuraminic acid
Matched Iupac: … (2R,4S,5R,6R)-5-acetamido-2,4-dihydroxy-6-[(1R,2R)-1,2,3-trihydroxypropyl]oxane-2-carboxylic acid
Matched Description: … N-acetylneuraminic acid occurs in many polysaccharides, glycoproteins, and glycolipids in animals and ... An N-acyl derivative of neuraminic acid. …
Deutarserine is under investigation in clinical trial NCT04158687 (A Phase 2 Study to Evaluate the Safety and Efficacy of CTP-692 as an Adjunctive Treatment in Adults With Schizophrenia).
Investigational
Matched Synonyms: … D-serine-2-d …
Matched Description: … Deutarserine is under investigation in clinical trial NCT04158687 (A Phase 2 Study to Evaluate the Safety and
Experimental
Matched Synonyms: … N-Propyl-tartramic acid ... N-Propyl-L-tartramate …
Matched Name: … (2R,3R)-2,3-Dihydroxy-4-oxo-4-(propylamino)butanoic acid
Matched Iupac: … (2R,3R)-2,3-dihydroxy-3-(propylcarbamoyl)propanoic acid
Etidronic acid is a first generation bisphosphonate similar to clodronic acid and tiludronic acid. These drugs were developed to mimic the action of pyrophosphate, a regulator of calcification and decalcification. Etidronate’s use has decreased over the years in favor of the third generation, nitrogen containing bisphosphonate zoledronic acid, ibandronic acid,...
Approved
Matched Synonyms: … Etidronic acid ... acide étidronique ... acidum etidronicum …
Matched Name: … Etidronic acid
Matched Iupac: … (1-hydroxy-1-phosphonoethyl)phosphonic acid
Matched Description: … Etidronic acid is a first generation bisphosphonate similar to [clodronic acid] and [tiludronic acid] ... ], [ibandronic acid], [minodronic acid], and [risedronic acid]. ... A203111] These drugs were developed to mimic the action of pyrophosphate, a regulator of calcification and
Matched Mixtures name: … Ntp-etidronate Calcium …
Matched Categories: … etidronic acid and calcium, sequential ... Drugs Affecting Bone Structure and Mineralization ... etidronic acid
Daprodustat is a small-molecule hypoxia-inducible factor (HIF) prolyl hydroxylase (PHD) inhibitor that was developed by GSK.[A254167,A254162] Patients with CKD cannot induce erythropoietin (EPO) production in response to hypoxia or anemia. As a potent inhibitor of PHD1, PHD2 and PHD3 (≥ 1000-fold selectivity), daprodustat stabilizes cellular HIF1α and HIF2α and the induces...
Approved
Investigational
Matched Synonyms: … Glycine, N-((1,3-dicyclohexylhexahydro-2,4,6-trioxo-5-pyrimidinyl)carbonyl)- …
Matched Iupac: … 2-[(1,3-dicyclohexyl-2,4,6-trioxo-1,3-diazinan-5-yl)formamido]acetic acid
Matched Description: … HIF1α and HIF2α and the induces erythropoiesis. ... As a potent inhibitor of PHD1, PHD2 and PHD3 (≥ 1000-fold selectivity), daprodustat stabilizes cellular ... to erythropoiesis-stimulating agents regarding the change in the hemoglobin level from baseline and
Matched Categories: … Amino Acids, Peptides, and Proteins ... Blood and Blood Forming Organs ... Amino Acids ... Hypoxia-Inducible Factor-Proline Dioxygenases, antagonists & inhibitors …
Experimental
Matched Synonyms: … L-3-(2-thienyl)alanine ... beta-(2-Thienyl)-L-alanine
Matched Name: … beta-2-Thienyl-L-alanine
Matched Iupac: … (2S)-2-amino-3-(thiophen-2-yl)propanoic acid
Furosemide is a potent loop diuretic that acts on the kidneys to ultimately increase water loss from the body. It is an anthranilic acid derivative. Furosemide is used for edema secondary to various clinical conditions, such as congestive heart failure exacerbation, liver failure, renal failure, and high blood pressure. It...
Approved
Vet approved
Matched Synonyms: … 4-Chloro-5-sulfamoyl-N-furfuryl-anthranilic acid ... 4-Chloro-N-furfuryl-5-sulfamoylanthranilic acid ... 4-Chloro-N-(2-furylmethyl)-5-sulfamoylanthranilic acid
Matched Iupac: … 4-chloro-2-{[(furan-2-yl)methyl]amino}-5-sulfamoylbenzoic acid
Matched Description: … It is an anthranilic acid derivative. ... Furosemide has a fast onset and short duration of action and has been used safely and effectively in ... both pediatric and adult patients. …
Matched Categories: … Acids, Carbocyclic ... Carboxylic Acids ... High-Ceiling Diuretics and Potassium-Sparing Agents ... furosemide and potassium ... furosemide and potassium-sparing agents …
Matched Products: … Ntp-furosemide ... Nu-furosemide Tablets …
Experimental
Matched Synonyms: … p-Iodo-L-phenylalanine
Matched Name: … 4-Iodo-L-phenylalanine
Matched Iupac: … (2S)-2-amino-3-(4-iodophenyl)propanoic acid
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids ... Amino Acids, Cyclic ... Amino Acids, Aromatic …
Acetylcysteine is an antioxidant and glutathione inducer indicated for mucolytic therapy and the treatment of acetaminophen overdose.[L31378,L31383,L31388,L31478] Acetylcysteine has also been studied for a wide variety of off-label indications with mixed results.[A228158,A228163,A228168] Acetylcysteine was granted FDA approval on 14 September 1963.
Approved
Investigational
Matched Synonyms: … NAC ... Mercapturic acid ... (R)-mercapturic acid
Matched Iupac: … (2R)-2-acetamido-3-sulfanylpropanoic acid
Matched Description: … Acetylcysteine is an antioxidant and glutathione inducer indicated for mucolytic therapy and the treatment …
Matched Mixtures name: … Levomefolate Calcium Acetylcysteine and Mecobalamin Algal ... Levomefolate Calcium, Acetylcysteine, Mecobalamin and Algal ... L-Methyl MC NAC
Matched Categories: … Amino Acids, Peptides, and Proteins ... Cough and Cold Preparations ... Amino Acids ... Amino Acids, Neutral ... Amino Acids, Sulfur …
Matched Products: … Acetadote ... N-ACE ... N - ACE …
Dipivefrin is a prodrug of adrenaline, which is used to treat glaucoma. It is available as ophthalmic solution (eye drops).
Approved
Matched Categories: … Antiglaucoma Preparations and Miotics …
Matched Products: … Propine ... PROPINE ... Propine Liq 0.1% …
Experimental
Matched Synonyms: … 2,3-Dimercaptopropanesulfonic acid ... 2,3-Dimercapto-1-propane sulfonate …
Matched Name: … 2,3-Dimercapto-1-propanesulfonic acid
Matched Iupac: … 2,3-disulfanylpropane-1-sulfonic acid
Experimental
Matched Name: … Para-Iodo-D-Phenylalanine Hydroxamic Acid
Matched Iupac: … (2R)-2-amino-N-hydroxy-3-(4-iodophenyl)propanamide …
Mafenide is a sulfonamide-type antimicrobial agent used to treat severe burns. It acts by reducing the bacterial population present in the burn tissue and promotes healing of deep burns. In 1998, mafenide acetate was approved under the FDA’s accelerated approval regulations. In November 2022, the use of mafenide acetate (powder...
Approved
Vet approved
Withdrawn
Matched Description: … It acts by reducing the bacterial population present in the burn tissue and promotes healing of deep ... [L36773] In 1998, mafenide acetate was approved under the FDA’s accelerated approval regulations. ... In November 2022, the use of mafenide acetate (powder for 5% topical solution) was withdrawn by the FDA …
Matched Salts name: … Mafenide Acetate
Matched Categories: … Folic Acid Antagonists ... Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics …
Matched Products: … Mafenide acetate ... Mafenide Acetate
Experimental
Matched Name: … (3R)-3-ethyl-N-[(4-methylphenyl)sulfonyl]-L-aspartic acid
Matched Iupac: … (2R,3S)-2-ethyl-3-(4-methylbenzenesulfonamido)butanedioic acid
Investigational
Matched Synonyms: … Immunoglobulin g4 (224-proline,233-alanine,234-alanine), anti-(human dickkopf-1) (human-mus musculus …
Experimental
Matched Name: … N-[Isoleucinyl]-N'-[adenosyl]-diaminosufone …
Matched Iupac: … (2S,3S)-2-amino-N-({[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl}sulfamoyl …
A nitrogen mustard alkylating agent used as antineoplastic agent for the treatment of various malignant and nonmalignant diseases. Although it is less toxic than most other nitrogen mustards, it has been listed as a known carcinogen in the Fourth Annual Report on Carcinogens (NTP 85-002, 1985). (Merck Index, 11th ed)
Approved
Matched Synonyms: … N,N-di-2-chloroethyl-γ-p-aminophenylbutyric acid ... N,N-di-2-chloroethyl-gamma-p-aminophenylbutyric acid ... Phenylbutyric acid nitrogen mustard …
Matched Iupac: … 4-{4-[bis(2-chloroethyl)amino]phenyl}butanoic acid
Matched Description: … nitrogen mustard alkylating agent used as antineoplastic agent for the treatment of various malignant and ... nitrogen mustards, it has been listed as a known carcinogen in the Fourth Annual Report on Carcinogens (NTP
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Phytic acid is under investigation in clinical trial NCT01000233 (Value of Oral Phytate (InsP6) in the Prevention of Progression of the Cardiovascular Calcifications).
Investigational
Matched Synonyms: … Acido fitico ... Fytic acid ... Acide fytique …
Matched Name: … Phytic acid
Matched Iupac: … {[(1s,2R,3R,4r,5S,6S)-2,3,4,5,6-pentakis(phosphonooxy)cyclohexyl]oxy}phosphonic acid
Matched Description: … Phytic acid is under investigation in clinical trial NCT01000233 (Value of Oral Phytate (InsP6) in the …
Investigational
Matched Synonyms: … acid ... (5-(3-(2-amino-4-oxo-4,7-dihydro-3 h-pyrrolo(2,3-d)pyrimidin-6-yl)propyl)thiophene-2-carbonyl)-l-glutamic
Matched Iupac: … (3-{2-amino-4-oxo-3H,4H,7H-pyrrolo[2,3-d]pyrimidin-6-yl}propyl)thiophen-2-yl]formamido}pentanedioic acid
Experimental
Matched Synonyms: … N-m-Hydroxylbenzoylglycine ... 3-hydroxyhippuric acid ... 2-[(3-hydroxyphenyl)formamido]acetic acid
Matched Name: … m-Hydroxyhippuric acid
Matched Iupac: … 2-[(3-hydroxyphenyl)formamido]acetic acid
Matched Categories: … Benzamides and benzamide derivatives ... Acids, Carbocyclic ... Keto Acids ... Carboxylic Acids
Approved
Matched Synonyms: … Lysine vasopressin ... Vasopressin, 8-L-lysine
Matched Iupac: … [(C-hydroxycarbonimidoyl)methyl]hexanimidic acid ... 5,8,11,14,17-pentaazacycloicosa-5,8,11,14,17-pentaene-4-carbonyl]pyrrolidin-2-yl](hydroxy)methylidene}amino)-N- …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Pituitary and Hypothalamic Hormones and Analogues ... Hormones, Hormone Substitutes, and Hormone Antagonists ... Sex Hormones and Insulins ... Vasopressin and Analogues …
Experimental
Matched Name: … N-[O-Phosphono-Pyridoxyl]-Isoleucine
Matched Iupac: … 2R,3S)-2-[({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methyl)amino]-3-methylpentanoic acid
Experimental
Matched Name: … N-Pyridoxyl-Glycine-5-Monophosphate …
Matched Iupac: … 2-[({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methyl)amino]acetic acid
Displaying drugs 751 - 775 of 4286 in total