Displaying drugs 751 - 775 of 2872 in total
Apitegromab
Apitegromab is under investigation in clinical trial NCT03921528 (An Active Treatment Study of SRK-015 in Patients With Type 2 or Type 3 Spinal Muscular Atrophy).
Investigational
Matched Synonyms: … Immunoglobulin g4 (234-proline), anti-(human progrowth differentiation factor 8) (human monoclonal srk ... -015 .gamma.4-chain), disulfide with human monoclonal srk-015 .lambda. …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Briquilimab
Briquilimab is a humanized aglycosylated IgG1 kappa monoclonal antibody targeting CD117 (cKit).
Investigational
Matched Synonyms: … IMMUNOGLOBULIN G1 (297-GLUTAMINE), ANTI-(HUMAN C-KIT RECEPTOR) (HUMAN-MUS MUSCULUS MONOCLONAL JSP191 ... .GAMMA.1-CHAIN), DISULFIDE WITH HUMAN-MUS MUSCULUS MONOCLONAL JSP191 .KAPPA. …
Litifilimab
Litifilimab is under investigation in clinical trial NCT05531565 (A Study to Assess the Efficacy and Safety of BIIB059 (Litifilimab) in Participants With Active Subacute Cutaneous Lupus Erythematosus (SCLE) And/or Chronic Cutaneous Lupus Erythematosus (CCLE) With or Without Systemic Manifestations and Refractory And/or Intolerant to Antimalarial Therapy).
Investigational
Matched Synonyms: … Immunoglobulin g1, anti-(human blood dendritic cell antigen 2) (human-mus musculus monoclonal biib059 ... .gamma.1-chain), disulfide with human-mus musculus monoclonal biib059 .kappa. …
Matched Description: … And/or Intolerant to Antimalarial Therapy). ... Litifilimab is under investigation in clinical trial NCT05531565 (A Study to Assess the Efficacy and ... of BIIB059 (Litifilimab) in Participants With Active Subacute Cutaneous Lupus Erythematosus (SCLE) And …
Matched Description: … And/or Intolerant to Antimalarial Therapy). ... Litifilimab is under investigation in clinical trial NCT05531565 (A Study to Assess the Efficacy and ... of BIIB059 (Litifilimab) in Participants With Active Subacute Cutaneous Lupus Erythematosus (SCLE) And …
N-Carbamoylaspartic acid
Experimental
Matched Synonyms: … Ureidosuccinic acid ... 2-Ureidobutanedioic acid ... L-N-Carbamoylaspartic acid …
Matched Name: … N-Carbamoylaspartic acid …
Matched Iupac: … (2S)-2-(carbamoylamino)butanedioic acid …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids, Acidic ... Amino Acids ... Excitatory Amino Acids ... Amino Acids, Dicarboxylic …
Matched Name: … N-Carbamoylaspartic acid …
Matched Iupac: … (2S)-2-(carbamoylamino)butanedioic acid …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids, Acidic ... Amino Acids ... Excitatory Amino Acids ... Amino Acids, Dicarboxylic …
Efineptakin alfa
Efineptakin alfa (also known as NT-I7) is a long-acting human interleukin-7 (IL-7) fusion protein that promotes T-cell development, contributing to the immune response. Compared to endogenous IL-7, NT-I7 is more stable and potent, has a longer half-life, and has better bioavailability. This drug is currently being investigated in the areas...
Investigational
Matched Synonyms: … Recombinant human IL-7-HYFC ... Recombinant human interleukin-7 fused to a hybrid crystallizable fragment region of a human antibody ... Recombinant human interleukin-7 fused to a hybrid crystallizable fragment region of a human antibody …
Matched Description: … Compared to endogenous IL-7, NT-I7 is more stable and potent, has a longer half-life, and has better ... Efineptakin alfa (also known as NT-I7) is a long-acting human interleukin-7 (IL-7) fusion protein that ... This drug is currently being investigated in the areas of oncology, immunology, and infectious disease …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins …
Matched Description: … Compared to endogenous IL-7, NT-I7 is more stable and potent, has a longer half-life, and has better ... Efineptakin alfa (also known as NT-I7) is a long-acting human interleukin-7 (IL-7) fusion protein that ... This drug is currently being investigated in the areas of oncology, immunology, and infectious disease …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins …
Acyclovir
Acyclovir is a deoxynucleoside analog antiviral used to treat herpes simplex, Varicella zoster, herpes zoster, herpes labialis, and acute herpetic keratitis.[L7303,L7315,L7318,L7321,L7324,L7327] Acyclovir is generally used first line in the treatment of these viruses and some products are indicated for patients as young as 6 years old. Acyclovir was granted FDA...
Approved
Matched Description: … analog antiviral used to treat herpes simplex, _Varicella zoster_, herpes zoster, herpes labialis, and ... L7315,L7318,L7321,L7324,L7327] Acyclovir is generally used first line in the treatment of these viruses and …
Matched Categories: … Acyclovir and prodrug ... Nucleic Acid Synthesis Inhibitors ... Nucleosides and Nucleotides ... Nucleosides and Nucleotides Excl. Reverse Transcriptase Inhibitors …
Matched Products: … ACIC 200 ... ACIC 400 ... ACIC 800 …
Matched Categories: … Acyclovir and prodrug ... Nucleic Acid Synthesis Inhibitors ... Nucleosides and Nucleotides ... Nucleosides and Nucleotides Excl. Reverse Transcriptase Inhibitors …
Matched Products: … ACIC 200 ... ACIC 400 ... ACIC 800 …
Vinylsulfonic acid
Experimental
Matched Synonyms: … Vinylsulphonic acid ... Ethylenesulfonic acid …
Matched Name: … Vinylsulfonic acid …
Matched Iupac: … ethenesulfonic acid …
Matched Categories: … Acids ... Sulfur Acids ... Acids, Noncarboxylic …
Matched Name: … Vinylsulfonic acid …
Matched Iupac: … ethenesulfonic acid …
Matched Categories: … Acids ... Sulfur Acids ... Acids, Noncarboxylic …
Olinvacimab
Olinvacimab is under investigation in clinical trial NCT03033524 (Trial to Evaluate the Safety of Ttac-0001(tanibirumab) in Recurrent Glioblastoma).
Investigational
Matched Synonyms: … Immunoglobulin g1, anti-(human vascular endothelial growth factor receptor 2) (human monoclonal ttac- ... Fully human monoclonal antibody targets vascular endothelial growth factor receptor 2 ... 0001 heavy chain), disulfide with human monoclonal ttac-0001 light chain, dimer …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Phloretic acid
Experimental
Matched Synonyms: … Phloretic acid ... Phloretinic acid ... Dihydro-p-coumaric acid …
Matched Name: … Phloretic acid …
Matched Iupac: … 3-(4-hydroxyphenyl)propanoic acid …
Matched Categories: … Carboxylic Acids ... Acids, Carbocyclic …
Matched Name: … Phloretic acid …
Matched Iupac: … 3-(4-hydroxyphenyl)propanoic acid …
Matched Categories: … Carboxylic Acids ... Acids, Carbocyclic …
D-tartaric acid
Experimental
Matched Synonyms: … (-)-Tartaric acid ... D-tartaric acid ... D-threaric acid …
Matched Name: … D-tartaric acid …
Matched Iupac: … (2S,3S)-2,3-dihydroxybutanedioic acid …
Matched Name: … D-tartaric acid …
Matched Iupac: … (2S,3S)-2,3-dihydroxybutanedioic acid …
(R)-3-hydroxytetradecanoic acid
Experimental
Matched Synonyms: … (−)-3-hydroxymyristic acid ... (3R)-hydroxymyristic acid ... β-hydroxymyristic acid …
Matched Name: … (R)-3-hydroxytetradecanoic acid …
Matched Iupac: … (3R)-3-hydroxytetradecanoic acid …
Matched Name: … (R)-3-hydroxytetradecanoic acid …
Matched Iupac: … (3R)-3-hydroxytetradecanoic acid …
L-Lactic acid
Approved
Experimental
Matched Synonyms: … (+)-lactic acid ... L-Lactic acid ... (S)-lactic acid …
Matched Name: … L-Lactic acid …
Matched Iupac: … (2S)-2-hydroxypropanoic acid …
Matched Categories: … Hydroxy Acids ... Carboxylic Acids …
Matched Name: … L-Lactic acid …
Matched Iupac: … (2S)-2-hydroxypropanoic acid …
Matched Categories: … Hydroxy Acids ... Carboxylic Acids …
Tridecactide
Tridecactide, also known as alpha-corticotropin 1-13, is a deacetylated and deaminated alpha-melanocyte stimulating hormone, which may have antipyretic, anti-inflammatory, and antimicrobial effects. Tridecactide, along with metenkefalin, are under investigation as an immunomodulatory therapy for moderate to severe COVID-19.[L13874,L13877]
Investigational
Matched Synonyms: … alpha-1-13-corticotropin, human …
Matched Iupac: … hydroxypropanamido]-3-(4-hydroxyphenyl)propanamido]-3-hydroxypropanamido]-4-(methylsulfanyl)butanamido]butanoic acid …
Matched Description: … Tridecactide, also known as alpha-corticotropin 1-13, is a deacetylated and deaminated alpha-melanocyte ... stimulating hormone, which may have antipyretic, anti-inflammatory, and antimicrobial effects. …
Matched Iupac: … hydroxypropanamido]-3-(4-hydroxyphenyl)propanamido]-3-hydroxypropanamido]-4-(methylsulfanyl)butanamido]butanoic acid …
Matched Description: … Tridecactide, also known as alpha-corticotropin 1-13, is a deacetylated and deaminated alpha-melanocyte ... stimulating hormone, which may have antipyretic, anti-inflammatory, and antimicrobial effects. …
AMT-101
AMT-101 is a recombinant human interleukin-10 fusion protein.
Investigational
Matched Synonyms: … Recombinant human interleukin-10 fusion protein …
Matched Description: … AMT-101 is a recombinant human interleukin-10 fusion protein. …
Matched Description: … AMT-101 is a recombinant human interleukin-10 fusion protein. …
Phenolsulfonic acid
Experimental
Matched Synonyms: … Sulfocarbolic acid ... Phenolsulfonic acid ... p-Phenolsulfonic acid …
Matched Name: … Phenolsulfonic acid …
Matched Iupac: … 4-hydroxybenzene-1-sulfonic acid …
Matched Name: … Phenolsulfonic acid …
Matched Iupac: … 4-hydroxybenzene-1-sulfonic acid …
Zinpentraxin alfa
Zinpentraxin alfa is a recombinant form of PTX-2, a naturally circulating human protein. It is under investigation in clinical trial NCT01981850 (A Phase 2 Study Of PRM-151 In Subjects With Myelofibrosis).
Investigational
Matched Synonyms: … Recombinant human pentraxin-2 ... RECOMBINANT HUMAN SERUM AMYLOID P ... Serum amyloid P protein (recombinant human PRM 151) …
Matched Description: … Zinpentraxin alfa is a recombinant form of PTX-2, a naturally circulating human protein. …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Description: … Zinpentraxin alfa is a recombinant form of PTX-2, a naturally circulating human protein. …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Serplulimab
Investigational
Matched Synonyms: … Immunoglobulin g4 (228-proline), anti-(human programmed cell death protein 1) (human-mus musculus monoclonal ... hlx10 .gamma.4-chain), disulfide with human-mus musculus monoclonal hlx10 .kappa. …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES …
Isobutyric acid
Experimental
Matched Synonyms: … iso-butyric acid ... α-isobutyric acid ... 2-methyl-propionic acid …
Matched Name: … Isobutyric acid …
Matched Iupac: … 2-methylpropanoic acid …
Matched Categories: … Fatty Acids ... Acids, Acyclic ... Carboxylic Acids ... Fatty Acids, Volatile …
Matched Name: … Isobutyric acid …
Matched Iupac: … 2-methylpropanoic acid …
Matched Categories: … Fatty Acids ... Acids, Acyclic ... Carboxylic Acids ... Fatty Acids, Volatile …
Lumiliximab
Lumiliximab is a chimeric monoclonal antibody which is used as an immunosuppressive drug. It is a primatized anti-CD23 macaque/human chimeric antibody that inhibits the production of the IgE antibody, for the potential treatment of allergic conditions. Lumiliximab was developed by IDEC Pharmaceuticals, which was acquired by Biogen. Clinical trials for...
Investigational
Matched Synonyms: … IMMUNOGLOBULIN G1, ANTI-(HUMAN IMMUNOGLOBULIN E RECEPTOR TYPE II) (HUMAN-MACACA IRUS MONOCLONAL IDEC- ... IMMUNOGLOBULIN G1, ANTI-(HUMAN IMMUNOGLOBULIN E RECEPTOR TYPE II) (HUMAN-MACACA IRUS MONOCLONAL IDEC- ... 152 .GAMMA.1-CHAIN), DISULFIDE WITH HUMAN-MACACA IRUS MONOCLONAL IDEC-152 .KAPPA. …
Matched Description: … Clinical trials for CLL were terminated in 2010, and for allergic asthma in 2007. ... It is a primatized anti-CD23 macaque/human chimeric antibody that inhibits the production of the IgE …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Description: … Clinical trials for CLL were terminated in 2010, and for allergic asthma in 2007. ... It is a primatized anti-CD23 macaque/human chimeric antibody that inhibits the production of the IgE …
Matched Categories: … Amino Acids, Peptides, and Proteins …
2,2-Dimethylbutyrate
Investigational
Matched Synonyms: … Dimebutic acid ... 2,2-dimethylbutanoic acid ... 2,2-dimethylbutyric acid …
Matched Iupac: … 2,2-dimethylbutanoic acid …
Matched Categories: … Fatty Acids ... Acids, Acyclic ... Carboxylic Acids ... Fatty Acids, Volatile …
Matched Iupac: … 2,2-dimethylbutanoic acid …
Matched Categories: … Fatty Acids ... Acids, Acyclic ... Carboxylic Acids ... Fatty Acids, Volatile …
Aminosalicylic acid
An antitubercular agent often administered in association with isoniazid. The sodium salt of the drug is better tolerated than the free acid.
Approved
Matched Synonyms: … Aminosalicylic acid ... 4-aminosalicylic acid ... p-aminosalicylic acid …
Matched Name: … Aminosalicylic acid …
Matched Iupac: … 4-amino-2-hydroxybenzoic acid …
Matched Description: … The sodium salt of the drug is better tolerated than the free acid. …
Matched Categories: … Aminosalicylic Acid and Derivatives ... Acids, Carbocyclic ... Hydroxy Acids ... Carboxylic Acids ... Aminosalicylic Acids …
Matched Name: … Aminosalicylic acid …
Matched Iupac: … 4-amino-2-hydroxybenzoic acid …
Matched Description: … The sodium salt of the drug is better tolerated than the free acid. …
Matched Categories: … Aminosalicylic Acid and Derivatives ... Acids, Carbocyclic ... Hydroxy Acids ... Carboxylic Acids ... Aminosalicylic Acids …
Foscarnet
An antiviral agent used in the treatment of cytomegalovirus retinitis. Foscarnet also shows activity against human herpes viruses and HIV.
Approved
Matched Synonyms: … Carboxyphosphonic acid ... Phosphonoformic acid ... Phosphonomethanoic acid …
Matched Iupac: … phosphonoformic acid …
Matched Description: … Foscarnet also shows activity against human herpes viruses and HIV. …
Matched Categories: … Acids, Acyclic ... Carboxylic Acids ... Phosphonic Acid Derivatives ... Nucleic Acid Synthesis Inhibitors …
Matched Iupac: … phosphonoformic acid …
Matched Description: … Foscarnet also shows activity against human herpes viruses and HIV. …
Matched Categories: … Acids, Acyclic ... Carboxylic Acids ... Phosphonic Acid Derivatives ... Nucleic Acid Synthesis Inhibitors …
EDI-200
EDI-200 is a fusion protein consisting of human immunoglobim G1 constant region Fc region fused to the human receptor binding domain of ectodysplasin-A1.
Investigational
Matched Synonyms: … HUMAN IMMUNOGLOBULIN G1 CONSTANT REGION - HUMAN ECTODYSPLASIN-A1 RECEPTOR-BINDING DOMAIN FUSION PROTEIN …
Matched Description: … human receptor binding domain of ectodysplasin-A1. ... EDI-200 is a fusion protein consisting of human immunoglobim G1 constant region Fc region fused to the …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins …
Matched Description: … human receptor binding domain of ectodysplasin-A1. ... EDI-200 is a fusion protein consisting of human immunoglobim G1 constant region Fc region fused to the …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins …
Timolumab
Timolumab is a recombinant, fully-human, IgG4 immunoglobulin with antigen-binding specificity for human vascular adhesion protein-1 (VAP-1).
Investigational
Matched Synonyms: … recombinant, fully-human, IgG4 immunoglobulin with antigen-binding specificity for human vascular adhesion …
Matched Description: … Timolumab is a recombinant, fully-human, IgG4 immunoglobulin with antigen-binding specificity for human …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Description: … Timolumab is a recombinant, fully-human, IgG4 immunoglobulin with antigen-binding specificity for human …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Ofatumumab
Ofatumumab is a novel anti-CD20 monoclonal antibody that targets B-cells. It is an IgG1κ human monoclonal antibody produced from a recombinant murine cell line (NS0) via transgenic mouse and hybridoma technology. Ofatumumab works by recognizing antigens that are expressed on the tumour cells in certain cancers; however, the antigen is...
Approved
Matched Synonyms: … HuMax-CD20 ... HuMax-CD20, 2F2 …
Matched Description: … It is an IgG1κ human monoclonal antibody produced from a recombinant murine cell line (NS0) via transgenic ... mouse and hybridoma technology. ... In February 2020, FDA and EMA approved Supplemental Biologics License Application (sBLA) and Marketing …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES …
Matched Description: … It is an IgG1κ human monoclonal antibody produced from a recombinant murine cell line (NS0) via transgenic ... mouse and hybridoma technology. ... In February 2020, FDA and EMA approved Supplemental Biologics License Application (sBLA) and Marketing …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES …
Displaying drugs 751 - 775 of 2872 in total