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Displaying drugs 776 - 800 of 5282 in total
Mebeverine has been investigated for the treatment of Irritable Bowel Syndrome and Post-cholecystectomy Gastrointestinal Spasms.
Approved
Investigational
Matched Iupac: … 4-{ethyl[1-(4-methoxyphenyl)propan-2-yl]amino}butyl 3,4-dimethoxybenzoate …
Matched Description: … Mebeverine has been investigated for the treatment of Irritable Bowel Syndrome and Post-cholecystectomy …
Matched Salts cas: … 2753-45-9 …
Matched Categories: … Alimentary Tract and Metabolism …
Matched Products: … DUSPATIN 135 ... DUSPATAL 135MG ... DUSPATAL 200 MG …
Farudodstat (ASLAN003) is under investigation in clinical trial NCT03451084 (A Dose Optimisation Study of ASLAN003 in Acute Myeloid Leukemia).
Investigational
Matched Synonyms: … 2-((3,5-difluoro-3'-methoxy-1,1'-biphenyl-4-yl)amino)nicotinic acid ... 2-(3,5-difluoro-3'-methoxybiphenyl-4-ylamino)nicotinic acid ... 2-((3,5-DIFLUORO-3'-METHOXY(1,1'-BIPHENYL)-4-YL)AMINO)-3-PYRIDINECARBOXYLIC ACID
Matched Iupac: … 2-({3,5-difluoro-3'-methoxy-[1,1'-biphenyl]-4-yl}amino)pyridine-3-carboxylic acid
Matched Categories: … Acids, Heterocyclic …
Lamotrigine is an antiepileptic drug belonging in the phenyltriazine class. It is used in the treatment of both epilepsy and as a mood stabilizer in bipolar disorder. Lamotrigine is the first medication since lithium granted Food and Drug Administration (FDA) approval for the maintenance treatment of bipolar type I. It...
Approved
Investigational
Matched Description: … It is used in the treatment of both epilepsy and as a mood stabilizer in bipolar disorder. ... Lamotrigine is the first medication since lithium granted Food and Drug Administration (FDA) approval ... [A191350] Lamotrigine has relatively few side-effects and does not require laboratory monitoring. …
Matched Categories: … Calcium-Regulating Hormones and Agents …
Matched Products: … LAMOTRIGIN ACIS 25MG ... LAMOTRIGIN ACIS 50MG ... LAMOTRIGIN ACIS 100MG …
Experimental
Matched Synonyms: … (R)-(+)-Tetrahydro-2-furoic acid ... (2R)-Tetrahydro-2-furancarboxylic acid ... (S)-(-)-2-Tetrahydrofuroic acid
Matched Name: … (S)-2-Tetrahydrofuroic acid
Matched Iupac: … (2R)-oxolane-2-carboxylic acid
Vigabatrin is an analog of gamma-aminobutyric acid (GABA), the main inhibitory neurotransmitter in the central nervous system, used in the treatment of refractory seizures and infantile spasms. It irreversibly inhibits the enzyme responsible for GABA metabolism, thereby increasing levels of circulating GABA. Although administered as a racemic mixture, only the...
Approved
Matched Synonyms: … 4-Amino-5-hexenoic acid ... Vinyl gamma-aminobutyric acid ... gamma-Vinyl-gamma-aminobutyric acid
Matched Iupac: … 4-aminohex-5-enoic acid
Matched Description: … Vigabatrin is an analog of gamma-aminobutyric acid ([GABA]), the main inhibitory neurotransmitter in ... the central nervous system, used in the treatment of refractory seizures and infantile spasms. ... [A202037] It was first introduced as an antiepileptic agent in the United Kingdom in 1989 and was …
Matched Categories: … Acids, Acyclic ... Carboxylic Acids ... Fatty Acids ... Fatty Acid Derivatives ... Cytochrome P-450 CYP2C9 Inducers …
Methopterin is thought to have effects on osteoclasts and to inhibit inflammatory bone destruction.
Investigational
Matched Synonyms: … 10-methylfolic acid ... N10-methylfolic acid ... 10-methylpteroylglutamic acid
Matched Iupac: … acid ... (2S)-2-[(4-{[(2-amino-4-oxo-3,4-dihydropteridin-6-yl)methyl](methyl)amino}phenyl)formamido]pentanedioic …
Matched Description: … Methopterin is thought to have effects on osteoclasts and to inhibit inflammatory bone destruction. …
Experimental
Matched Synonyms: … Polyethylene glycol 3500 …
Matched Name: … Polyethylene glycol 3500 …
Matched Products: … Polyethylene Glycol (3350) …
Experimental
Matched Synonyms: … N-formyl hydroxyaminoacetic acid ... N-hydroxyformamidoacetic acid ... N-formyl-N- hydroxyaminoacetic acid
Matched Iupac: … 2-(N-hydroxyformamido)acetic acid
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids
Vorinostat (rINN) or suberoylanilide hydroxamic acid (SAHA), is a drug currently under investigation for the treatment of cutaneous T cell lymphoma (CTCL), a type of skin cancer, to be used when the disease persists, gets worse, or comes back during or after treatment with other medicines. It is the first...
Approved
Investigational
Matched Synonyms: … Suberanilohydroxamic acid ... Suberoylanilide hydroxamic acid ... Octanedioic acid hydroxyamide phenylamide …
Matched Description: … Vorinostat (rINN) or suberoylanilide hydroxamic acid (SAHA), is a drug currently under investigation ... - 4.4 months in earlier studies). ... recurrent glioblastoma multiforme, resulting in a median overall survival of 5.7 months (compared to 4
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Carboxylic Acids ... Hydroxy Acids ... Hydroxamic Acids
Experimental
Matched Synonyms: … 3-morpholinopropanesulfonic acid ... Morpholinopropane sulfonic acid
Matched Name: … 3-(N-morpholino)propanesulfonic acid
Matched Iupac: … 3-(morpholin-4-yl)propane-1-sulfonic acid
Tannic acid is a polyphenolic compound. It is a type of the commercially available tannins. It acts as a weak acid. Tannic acid is found in the nutgalls formed by insects on twigs of certain oak trees (Quercus infectoria and other Quercus species). It is removed and used as medicine....
Approved
Matched Synonyms: … Tannic acid ... Gallotannic acid
Matched Name: … Tannic acid
Matched Iupac: … (2R,3R,4S,5R)-4,5,6-tris[3,4-dihydroxy-5-(3,4,5-trihydroxybenzoyloxy)benzoyloxy]-2-{[3,4-dihydroxy-5- …
Matched Description: … Tannic acid is also taken by mouth and applied directly for bleeding, chronic diarrhea, dysentery, bloody ... and other Quercus species). ... and poison ivy. …
Experimental
Matched Synonyms: … Dichlorocyanuric acid ... Dichloroisocyanuric acid
Matched Products: … SALUT sterilization water
Alclofenac is a non-steroidal anti-inflammatory drug. It was withdrawn from the market in the United Kingdom in 1979.
Approved
Withdrawn
Matched Synonyms: … [4-(allyloxy)-3-chlorophenyl]acetic acid ... 3-Chloro-4-(2-propenyloxy)benzeneacetic acid ... (4-Allyloxy-3-chlorphenyl)essigsäure …
Matched Iupac: … 2-[3-chloro-4-(prop-2-en-1-yloxy)phenyl]acetic acid
Matched Categories: … Acetic Acid Derivatives and Related Substances ... Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids ... Acids, Carbocyclic ... Carboxylic Acids
Experimental
Matched Synonyms: … (3R)-3-Phenyl-3-[({4-[4-(4-pyridinyl)phenyl]-2-thienyl}carbonyl)amino]propanoic acid ... 3-phenyl-3-({[4-(4-pyridin-4-ylphenyl)thien-2-yl]carbonyl}amino)propanoic acid
Matched Iupac: … (3R)-3-phenyl-3-({4-[4-(pyridin-4-yl)phenyl]thiophen-2-yl}formamido)propanoic acid
Experimental
Matched Synonyms: … Benzeneboronic acid ... Borophenylic acid
Matched Name: … Phenylboronic acid
Matched Iupac: … phenylboronic acid
Matched Categories: … Acids ... Acids, Noncarboxylic …
Experimental
Matched Synonyms: … 5,7-Dichloroquinurenic acid ... 5,7-Dichorokynurenic acid
Matched Name: … 5,7-Dichlorokynurenic acid
Matched Iupac: … 5,7-dichloro-4-hydroxyquinoline-2-carboxylic acid
Matched Categories: … Acids, Heterocyclic ... Excitatory Amino Acid Agents ... Excitatory Amino Acid Antagonists …
An antilipemic agent which lowers cholesterol, triglycerides, serum beta-lipoproteins and phospholipids. It acts by interfering with the enzymatic steps involved in the conversion of acetate to hydroxymethylglutaryl coenzyme A as well as inhibiting the activity of HYDROXYMETHYLGLUTARYL COA REDUCTASES which is the rate limiting enzyme in the biosynthesis of cholesterol.
Experimental
Matched Synonyms: … Dicrotalic acid ... 3-hydroxy-3-methylglutaric acid
Matched Iupac: … 3-hydroxy-3-methylpentanedioic acid
Matched Description: … An antilipemic agent which lowers cholesterol, triglycerides, serum beta-lipoproteins and phospholipids …
Matched Categories: … Acids, Acyclic ... Carboxylic Acids ... Dicarboxylic Acids
Experimental
Investigational
Matched Synonyms: … arsenous acid ... arsorous acid
Matched Name: … Arsenous acid
Matched Iupac: … arsorous acid
Investigational
Matched Synonyms: … Citric acid ethyl ester ... Citric acid triethyl ester …
Matched Categories: … Acids, Acyclic ... Carboxylic Acids ... Tricarboxylic Acids
Primary biliary cirrhosis, or PBC, is a progressive and chronic condition that leads to hepatic injury often resulting in end-stage liver failure that requires liver transplantation. Obeticholic acid is a farnesoid-X receptor (FXR) agonist used to treat this condition, possibly allowing for increased survival. In 2016, it was granted approval...
Approved
Matched Synonyms: … Obeticholic acid ... 6-ethylchenodeoxycholic acid ... 6-alpha-ethylchenodeoxycholic acid
Matched Name: … Obeticholic acid
Matched Iupac: … [a]phenanthren-1-yl]pentanoic acid ... (4R)-4-[(1R,3aS,3bS,4R,5R,5aS,7R,9aS,9bS,11aR)-5-ethyl-4,7-dihydroxy-9a,11a-dimethyl-hexadecahydro-1H-cyclopenta …
Matched Description: … The NDA from Intercept Pharmaceuticals was approved in November 2019 and obeticholic acid is expected ... obeticholic acid in patients with PBC and advanced cirrhosis (e.g. those with portal hypertension or ... Primary biliary cirrhosis, or PBC, is a progressive and chronic condition that leads to hepatic injury …
Matched Categories: … Bile Acids and Salts ... Bile acids and derivatives ... Alimentary Tract and Metabolism ... Bile and Liver Therapy ... Cholic Acids
An essential branched-chain amino acid important for hemoglobin formation.
Investigational
Nutraceutical
Matched Synonyms: … (2S)-2-Amino-4-methylpentanoic acid ... 2-Amino-4-methylvaleric acid ... (2S)-alpha-2-Amino-4-methylvaleric acid
Matched Iupac: … (2S)-2-amino-4-methylpentanoic acid
Matched Description: … An essential branched-chain amino acid important for hemoglobin formation. …
Matched Mixtures name: … Aminosyn II and Dextrose ... Aminosyn II and Dextrose ... NUTRINEAL PD-4 PERITONEAL DIALYSIS SOLUTION WITH 1.1% AMINO ACIDS
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids ... Amino Acids, Essential ... Amino Acids, Branched-Chain ... Proteinogenic Amino Acids
A benzimidazole that acts by interfering with carbohydrate metabolism and inhibiting polymerization of microtubules. [PubChem]
Approved
Vet approved
Matched Synonyms: … (5-benzoyl-1H-benzimidazol-2-yl)-carbamic acid methyl ester …
Matched Iupac: … methyl N-(6-benzoyl-1H-1,3-benzodiazol-2-yl)carbamate …
Matched Description: … A benzimidazole that acts by interfering with carbohydrate metabolism and inhibiting polymerization of …
Matched Categories: … Antiparasitic Products, Insecticides and Repellents ... Acids, Acyclic ... Carboxylic Acids
Matched Products: … MEBENDAZOL SUSPENSION 20 MG / ML …
Experimental
Matched Synonyms: … Propanimidic acid ... Propionic acid amide …
Investigational
Matched Synonyms: … 3a,6b,7b,12a-(OH)4-5b-cholanic acid ... (3α,5β,6β,7β,12α)-3,6,7,12-Tetrahydroxycholan-24-oic acid ... 3alpha,6beta,7beta,12alpha-Tetrahydroxy-5beta-cholanoic acid
Matched Name: … 3alpha,6beta,7beta,12alpha-tetrahydroxy-5beta-cholan-24-oic acid
Matched Iupac: … 4-{4,5,7,11-tetrahydroxy-9a,11a-dimethyl-hexadecahydro-1H-cyclopenta[a]phenanthren-1-yl}pentanoic acid
Palmitoyloleoyl-phosphatidylglycerol was a component of Surfaxin, discontinued in 2017, which acted as a surfactant [FDA Label]. The product was meant to compensate for alveolar surfactant deficiency and reduce to likelihood of alveolar collapse leading to acute respiratory collapse.
Approved
Experimental
Matched Synonyms: … 1-Palmitoyl-2-oleoyl-sn-glycero-3-(phospho-rac-(1-glycerol)) ... 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphoglycerol ... 1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphatidylglycerol …
Matched Name: … 1-Palmitoyl-2-oleoyl-sn-glycero-3-(phospho-rac-(1-glycerol)) …
Matched Iupac: … (2,3-dihydroxypropoxy)[(2R)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propoxy]phosphinic acid
Matched Description: … The product was meant to compensate for alveolar surfactant deficiency and reduce to likelihood of alveolar ... Palmitoyloleoyl-phosphatidylglycerol was a component of Surfaxin, discontinued in 2017, which acted as …
Matched Salts cas: … 268550-95-4
Matched Salts name: … 1-palmitoyl-2-oleoyl-sn-glycero-3-(phospho-rac-(1-glycerol)), sodium salt …
Displaying drugs 776 - 800 of 5282 in total