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Displaying drugs 776 - 800 of 930 in total
An oligosaccharide antibiotic produced by various streptomyces. [PubChem]
Approved
Investigational
Matched Synonyms: … (1R,2R,3S,4R,6S)-4,6-diamino-2-{[3-O-(2,6-diamino-2,6-dideoxy-beta-L-idopyranosyl)-beta-D-ribofuranosyl …
Matched Categories: … Alimentary Tract and Metabolism …
Investigational
Matched Synonyms: … 3-AMINO-1,5-DIHYDRO-5-METHYL-1-.BETA. …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Investigational
Matched Synonyms: … 1h-1,2,4-triazole-3-carboxamide, 1-(5-o-((9e)-1-oxo-9-octadecen-1-yl)-.beta.-d-ribofuranosyl)- …
Experimental
Matched Name: … L-Alpha-Phosphatidyl-Beta-Oleoyl-Gamma-Palmitoyl-Phosphatidylethanolamine …
Experimental
Matched Name: … 2-(Beta-D-Glucopyranosyl)-5-Methyl-1,2,3-Benzimidazole …
Experimental
Matched Name: … 2-(Beta-D-Glucopyranosyl)-5-Methyl-1,3,4-Benzothiazole …
Experimental
Matched Name: … 9-(2-Deoxy-Beta-D-Ribofuranosyl)-6-Methylpurine …
Scopolamine is a tropane alkaloid isolated from members of the Solanaceae family of plants, similar to atropine and hyoscyamine, all of which structurally mimic the natural neurotransmitter acetylcholine.[A228423, A228763] Scopolamine was first synthesized in 1959, but to date, synthesis remains less efficient than extracting scopolamine from plants. As an acetylcholine...
Approved
Investigational
Matched Synonyms: … 6-beta,7-beta-Epoxy-3-alpha-tropanyl S-(-)-tropate …
Matched Description: … nervous system and cholinergic signalling. ... vomiting associated with motion sickness and surgical procedures. ... available as both oral tablets and a transdermal delivery system. …
Matched Mixtures name: … Phenobarbital, Hyoscyamine Sulfate, Atropine Sulfate and Scopolamine Hydrobromide ... Phenobarbital, Hyoscyamine Sulfate, Atropine Sulfate and Scopolamine Hydrobromide …
Matched Categories: … Hypnotics and Sedatives ... Alimentary Tract and Metabolism ... Antiemetics and Antinauseants ... Mydriatics and Cycloplegics …
Tiazofurine has potential clinical use in cancer treatment as it is a potential inhibitor of Inosine- 5’-monophosphate (IMP) dehydrogenase .
Experimental
Matched Synonyms: … 2-Beta-D-ribofuranosyl-4-thiazolecarboxamide …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Nucleic Acids, Nucleotides, and Nucleosides …
Initially approved by the FDA in 2013, memantine is an N-methyl-D-aspartate (NMDA) receptor antagonist used in the management of Alzheimer's Disease (AD). It is different from many other Alzheimer's Disease medications, as it works by a different mechanism than the cholinesterase enzyme inhibitors normally employed in the management of Alzheimer's...
Approved
Investigational
Matched Description: … and excessive stimulation in Alzheimer's Disease [T556]. ... Memantine blocks the effects of glutamate, a neurotransmitter in the brain that leads to neuronal excitability ... doubling every 20 years, the prevalence of Alzheimer's Disease is predicted to reach 66 million by 2030 and
Matched Mixtures name: … Memantine and Donepezil Hydrochlorides Extended-release ... Memantine and Donepezil Hydrochlorides Extended-release ... Memantine and Donepezil Hydrochlorides Extended-release …
Matched Categories: … donepezil and memantine ... donepezil, memantine and Ginkgo folium …
Matched Products: … MEMANTIN HCL BETA 10MG ... MEMANTIN HCL BETA 20MG ... MEMANTIN HCL BETA 10MG/ML …
Experimental
Matched Synonyms: … 1-beta-D-Arabinofuranosylcytosine 5'-phosphate …
A purine nucleoside that has hypoxanthine linked by the N9 nitrogen to the C1 carbon of ribose. It is an intermediate in the degradation of purines and purine nucleosides to uric acid and in pathways of purine salvage. It also occurs in the anticodon of certain transfer RNA molecules. (Dorland,...
Experimental
Investigational
Matched Synonyms: … beta-Inosine …
Matched Description: … It is an intermediate in the degradation of purines and purine nucleosides to uric acid and in pathways …
Matched Categories: … Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics ... Nucleic Acids, Nucleotides, and Nucleosides …
Lutikizumab is under investigation in clinical trial NCT02087904 (A Study Evaluating the Safety, Efficacy, and Pharmacodynamic Effects of ABT-981 in Patients With Knee Osteoarthritis).
Investigational
Matched Synonyms: … Immunoglobulin, anti-(interleukin 1.beta./interleukin 1.alpha.) …
Matched Description: … Lutikizumab is under investigation in clinical trial NCT02087904 (A Study Evaluating the Safety, Efficacy, and
Matched Categories: … Amino Acids, Peptides, and Proteins …
Ezetimibe is a lipid-lowering compound that inhibits intestinal cholesterol and phytosterol absorption. The discovery and research of this drug began in the early 1990s, after the intravenous administration of radiolabelled ezetimibe in rats revealed that it was being localized within enterocytes of the intestinal villi - this prompted studies investigating...
Approved
Matched Description: … Ezetimibe is a lipid-lowering compound that inhibits intestinal cholesterol and phytosterol absorption ... The discovery and research of this drug began in the early 1990s, after the intravenous administration ... [A15202] By interfering with the intestinal uptake of cholesterol and phytosterols, ezetimibe reduces …
Matched Mixtures name: … Ezetimibe and Simvastatin ... Ezetimibe and Simvastatin ... Ezetimibe and Simvastatin …
Matched Categories: … simvastatin and ezetimibe ... pravastatin and ezetimibe ... atorvastatin and ezetimibe ... rosuvastatin and ezetimibe ... bempedoic acid and ezetimibe …
Matched Products: … EZETIMIB BETA 10 MG …
Prasterone, also known as dehydroepiandrosterone (DHEA) is a major C19 steroid produced by the adrenal cortex. It is also produced in small quantities in the testis and the ovary. Dehydroepiandrosterone (DHEA) can be converted to testosterone; androstenedione; estradiol; and estrone. Most of DHEA is sulfated (dehydroepiandrosterone sulfate) before secretion. In...
Approved
Investigational
Nutraceutical
Matched Synonyms: … 3-beta-hydroxy-5-androsten-17-one …
Matched Description: … It is also produced in small quantities in the testis and the ovary. ... Dehydroepiandrosterone (DHEA) can be converted to testosterone; androstenedione; estradiol; and estrone ... DHEA and DHEAS are readily available in the United States, where they are marketed as over-the-counter …
Matched Categories: … Androgens and Estrogens ... prasterone and estrogen ... Alimentary Tract and Metabolism ... Genito Urinary System and Sex Hormones ... Sex Hormones and Modulators of the Genital System …
Calcium glycerophosphate is a DB01373 salt of glycerophosphoric acid that forms a white, fine, slightly hygroscopic powder. The commercial product is a mixture of calcium beta-, and D-, and L -alpha-glycerophosphate. By FDA, calcium glycerophosphate is considered a generally recognized as safe (GRAS) food ingredient as a nutrient supplement (source...
Approved
Matched Synonyms: … Calcium beta-glycerophosphate …
Matched Description: … The commercial product is a mixture of calcium beta-, and D-, and L -alpha-glycerophosphate. ... phosphate levels and direct interaction with dental mineral [A27153]. ... suggested that calcium glycerophosphate promotes plaque-pH buffering, elevation of plaque [DB01373] and
Matched Mixtures name: … Somarexin and C 1000 ... NUTROPLEX LIQUID WITH IRON AND LYSINE …
Lecanemab is a recombinant humanized immunoglobulin gamma 1 (IgG1) monoclonal antibody directed against aggregated soluble and insoluble forms of amyloid beta (Aβ), which are implicated in the pathophysiology of Alzheimer’s disease. Lecanemab works to reduce Aβ plaques and prevent Aβ deposition in the brain [A253947,A253952] with high selectivity to Aβ...
Approved
Investigational
Matched Synonyms: … Immunoglobulin G1, anti-(human beta-amyloid protofibril) (human-mus musculus monoclonal BAN2401 heavy …
Matched Description: … insoluble forms of amyloid beta (Aβ), which are implicated in the pathophysiology of Alzheimer’s disease ... [L44537] Lecanemab works to reduce Aβ plaques and prevent Aβ deposition in the brain [A253947,A253952 ... recombinant humanized immunoglobulin gamma 1 (IgG1) monoclonal antibody directed against aggregated soluble and
Matched Categories: … Amyloid Beta-directed Antibodies ... Amino Acids, Peptides, and Proteins …
Investigational
Matched Synonyms: … Cotsiranib tgf-.beta.1 si-rna free acid component ... Stp-705 component tgf-.beta.1 si-rna free acid ... Tgf-.beta.1 si-rna free acid component of cotsiranib …
Experimental
Matched Name: … 2-deoxy-2-acetamido-beta-D-galactose-4-sulfate …
Experimental
Matched Name: … 1-Deoxy-1-acetylamino-beta-D-gluco-2-heptulopyranosonamide …
Experimental
Matched Synonyms: … beta-Heparin …
Matched Categories: … Blood and Blood Forming Organs …
A dideoxynucleoside analog that inhibits reverse transcriptase and has in vitro activity against HIV.
Approved
Investigational
Matched Synonyms: … 1-(2,3-Dideoxy-beta-D-glycero-pent-2-enofuranosyl)thymine …
Matched Description: … A dideoxynucleoside analog that inhibits reverse transcriptase and has in vitro activity against HIV. …
Matched Categories: … stavudine and lamivudine ... stavudine, lamivudine and nevirapine ... Nucleic Acids, Nucleotides, and Nucleosides ... Nucleoside and Nucleotide Reverse Transcriptase Inhibitors …
Streptomycin, an antibiotic derived from Streptomyces griseus, was the first aminoglycoside to be discovered and used in practice in the 1940s.[A233325,A233390] Selman Waksman and eventually Albert Schatz were recognized with the Nobel Prize in Medicine for their discovery of streptomycin and its antibacterial activity.[A233325,A232294] Although streptomycin was the first antibiotic...
Approved
Vet approved
Matched Synonyms: … diguanidino-3,5,6-trihydroxycyclohexyl 5-deoxy-2-O-(2-deoxy-2-methylamino-alpha-L-glucopyranosyl)-3-C-formyl-beta-L-lyxopentanofuranoside …
Matched Description: … Medicine for their discovery of streptomycin and its antibacterial activity. ... [A233325,A233390] Selman Waksman and eventually Albert Schatz were recognized with the Nobel Prize in ... Streptomycin, an antibiotic derived from _Streptomyces griseus_, was the first aminoglycoside to be discovered and
Matched Categories: … Alimentary Tract and Metabolism ... streptomycin and isoniazid …
Propranolol is a racemic mixture of 2 enantiomers where the S(-)-enantiomer has approximately 100 times the binding affinity for beta adrenergic receptors. Propranolol is used to treat a number of conditions but most commonly is used for hypertension.[L6901,L6904,L6907] Propranolol was granted FDA approval on 13 November 1967.
Approved
Investigational
Matched Synonyms: … beta-Propranolol …
Matched Description: … mixture of 2 enantiomers where the S(-)-enantiomer has approximately 100 times the binding affinity for beta
Matched Mixtures name: … Propranolol Hydrochloride and Hydrochlorothiazide ... Propranolol Hydrochloride and Hydrochlorothiazide ... Propranolol Hydrochloride and Hydrochlorothiazide …
Matched Categories: … Beta Blocking Agents and Thiazides ... Beta Blocking Agents, Non-Selective, and Thiazides ... Adrenergic beta-Antagonists ... propranolol and thiazides ... Beta Blocking Agents, Non-Selective …
Experimental
Matched Name: … 4-NITROPHENYL-(6-S-ALPHA-D-XYLOPYRANOSYL)-BETA-D-GLUCOPYRANOSIDE …
Displaying drugs 776 - 800 of 930 in total