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Displaying drugs 8051 - 8075 of 11622 in total

MM3122

Experimental
Matched Iupac: … }-2-phenylethyl]-2-(2-acetamidoacetamido)pentanediamide ... (2S)-N-[(1S)-1-{[(2S)-1-(1,3-benzothiazol-2-yl)-5-[(diaminomethylidene)amino]-1-oxopentan-2-yl]carbamoyl …
Matched Categories: … Heterocyclic Compounds, 2-Ring …

Tebipenem pivoxil

Investigational
Matched Iupac: … -7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carbonyloxy]methyl 2,2-dimethylpropanoate ... [(4R,5S,6S)-3-{[1-(4,5-dihydro-1,3-thiazol-2-yl)azetidin-3-yl]sulfanyl}-6-[(1R)-1-hydroxyethyl]-4-methyl …
Matched Categories: … Heterocyclic Compounds, 2-Ring …

2,3-Didehydroalanine

Experimental
Matched Iupac: … 2-aminoprop-2-enoic acid …

PD150606

Experimental
Matched Iupac: … (2S)-3-(4-iodophenyl)-2-sulfanylpropanoic acid …

Isoferulic acid

Experimental
Matched Iupac: … (2E)-3-(3-hydroxy-4-methoxyphenyl)prop-2-enoic acid …

Verubecestat

Verubecestat is under investigation for the treatment of Alzheimer's Disease, Prodromal Alzheimer's disease, and Amnestic Mild Cognitive Impairment. Verubecestat is Merck’s investigational oral β-site amyloid precursor protein cleaving enzyme (BACE1 or β secretase) inhibitor. In July 2013, Merck announced positive results for Phase Ib trials of Verubecestat. In the study,...
Investigational
Matched Iupac: … 2,5-dimethyl-1,1-dioxo-5,6-dihydro-2H-1lambda6,2,4-thiadiazin-5-yl]-4-fluorophenyl}-5-fluoropyridine-2- …

Efmarodocokin alfa

Efmarodocokin alfa is under investigation in clinical trial NCT04386616 (A Study to Evaluate the Safety and Efficacy of MSTT1041A (Astegolimab) or UTTR1147A in Patients With Severe COVID-19 Pneumonia).
Investigational

SB-743921

Investigational
Matched Iupac: … N-(3-aminopropyl)-N-[(1R)-1-(3-benzyl-7-chloro-4-oxo-4H-chromen-2-yl)-2-methylpropyl]-4-methylbenzamide …
Matched Categories: … Heterocyclic Compounds, 2-Ring …

Atrasentan

Atrasentan is a substance that is being studied in the treatment of cancer. It belongs to the family of drugs called endothelin-1 protein receptor antagonists. It is a novel, selective endothelin A receptor antagonist (SERA).
Investigational
Matched Iupac: … (2R,3R,4S)-4-(2H-1,3-benzodioxol-5-yl)-1-[(dibutylcarbamoyl)methyl]-2-(4-methoxyphenyl)pyrrolidine-3- …
Matched Categories: … Heterocyclic Compounds, 2-Ring …

Pipazethate

A non-narcotic oral antitussive agent.
Experimental
Matched Iupac: … -hexaene-2-carboxylate ... 2-[2-(piperidin-1-yl)ethoxy]ethyl 9-thia-2,4-diazatricyclo[8.4.0.0^{3,8}]tetradeca-1(14),3(8),4,6,10,12 …
Matched Categories: … Heterocyclic Compounds, 2-Ring …

CUDC-101

CUDC-101 has been used in trials studying the treatment of Cancer, Tumors, Liver Cancer, Breast Cancer, and Gastric Cancer, among others.
Investigational
Matched Categories: … Heterocyclic Compounds, 2-Ring …

Xanthohumol

Xanthohumol is under investigation in clinical trial NCT01367431 (Xanthohumol and Metabolic Syndrome).
Investigational
Matched Iupac: … (2E)-1-[2,4-dihydroxy-6-methoxy-3-(3-methylbut-2-en-1-yl)phenyl]-3-(4-hydroxyphenyl)prop-2-en-1-one …
Matched Categories: … Heterocyclic Compounds, 2-Ring …

MK-886

MK-886 is an experimental inhibitor of leukotriene synthesis.
Experimental
Matched Iupac: … 3-[3-(tert-butylsulfanyl)-1-[(4-chlorophenyl)methyl]-5-(propan-2-yl)-1H-indol-2-yl]-2,2-dimethylpropanoic …
Matched Categories: … Heterocyclic Compounds, 2-Ring …

Ochromycinone

Ochromycinone is under investigation in clinical trial NCT01047943 (STA-21 Topical Efficacy on Psoriasis).
Investigational

Indoprofen

A drug that has analgesic and anti-inflammatory properties. Following reports of adverse reactions including reports of carcinogenicity in animal studies it was withdrawn from the market worldwide.
Withdrawn
Matched Iupac: … 2-[4-(1-oxo-2,3-dihydro-1H-isoindol-2-yl)phenyl]propanoic acid …
Matched Categories: … Non COX-2 selective NSAIDS ... Heterocyclic Compounds, 2-Ring …

Dinitrochlorobenzene

Dinitrochlorobenzene has been used in trials studying the treatment of HIV Infections.
Investigational

Ipafricept

Ipafricept is under investigation in clinical trial NCT01608867 (A Dose Escalation Study of OMP-54F28 in Subjects With Solid Tumors).
Investigational

3D-185 free base

Investigational

Trabodenoson

Trabodenoson has been used in trials studying the treatment of Ocular Hypertension (OHT) and Primary Open-Angle Glaucoma (POAG).
Investigational
Matched Iupac: … [(2R,3S,4R,5R)-5-[6-(cyclopentylamino)-9H-purin-9-yl]-3,4-dihydroxyoxolan-2-yl]methyl nitrate …
Matched Categories: … Heterocyclic Compounds, 2-Ring …

Acefylline

Experimental
Matched Iupac: … 2-(1,3-dimethyl-2,6-dioxo-2,3,6,7-tetrahydro-1H-purin-7-yl)acetic acid …
Matched Categories: … Heterocyclic Compounds, 2-Ring …

Levonadifloxacin

Levonadifloxacin is under investigation in clinical trial NCT03405064 (Comparative Study of Levonadifloxacin (IV and Oral) With Linezolid (IV and Oral) in Acute Bacterial Skin and Skin Structure Infections (ABSSSI)).
Investigational
Matched Categories: … Heterocyclic Compounds, 2-Ring …

Naphthoquine

Naphthoquine is under investigation in clinical trial NCT01930331 (Safety, Tolerability, Pharmacokinetics and Efficacy of ARCO).
Investigational
Matched Iupac: … 2-[(tert-butylamino)methyl]-4-[(7-chloroquinolin-4-yl)amino]-5,6,7,8-tetrahydronaphthalen-1-ol …
Matched Categories: … Heterocyclic Compounds, 2-Ring …

Pirlindole

This drug is classified as a reversible inhibitor of monoamine oxidase A enzyme (also known as a RIMA drug). It was developed and is currently used as an antidepressant in Russia. Its chemical structure is similar to metralindole, and it also shares pharmacological properties with this drug. Pirlindole is a...
Experimental
Matched Salts cas: … 16154-78-2 …
Matched Categories: … Heterocyclic Compounds, 2-Ring …

1,8-Di-Hydroxy-4-Nitro-Anthraquinone

Experimental

Nogalaviketone

Experimental
Matched Iupac: … methyl 5,7-dihydroxy-2-methyl-4,6,11-trioxo-3,4,6,11-tetrahydrotetracene-1-carboxylate …
Displaying drugs 8051 - 8075 of 11622 in total