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Displaying drugs 8176 - 8200 of 9513 in total
N-(1-adamantyl)-N'-(4-guanidinobenzyl)urea
Experimental
Matched Iupac: … 3-(adamantan-1-yl)-1-({4-[(diaminomethylidene)amino]phenyl}methyl)urea …
Ketobemidone
Ketobemidone is a powerful opioid analgesic. It also has some NMDA-antagonist properties. This makes it useful for some types of pain that don't respond well to other opioids. The most commonly cited equalisation ratio for analgesic doses is 25 mg of ketobemidone hydrobromide to 60 mg of morphine hydrochloride or...
Investigational
Matched Iupac: … 1-[4-(3-hydroxyphenyl)-1-methylpiperidin-4-yl]propan-1-one …
Prinaberel
Prinaberel is an estrogen receptor beta agonist.
Investigational
Matched Iupac: … 7-ethenyl-2-(3-fluoro-4-hydroxyphenyl)-1,3-benzoxazol-5-ol …
D-phenylalanyl-N-benzyl-L-prolinamide
Experimental
Matched Iupac: … (2S)-1-[(2R)-2-amino-3-phenylpropanoyl]-N-benzylpyrrolidine-2-carboxamide …
N-(2-CHLORO-4-FLUOROBENZOYL)-N'-(5-HYDROXY-2-METHOXYPHENYL)UREA
Experimental
Matched Iupac: … 1-(2-chloro-4-fluorobenzoyl)-3-(5-hydroxy-2-methoxyphenyl)urea …
Benfluorex
Benfluorex is an anorectic and hypolipidemic agent that is structurally related to fenfluramine. It was patented and manufactured by a French pharmaceutical company Servier. The European Medicines Agency (EMA) recommended withdrawing all benfluorex containing medicines on 18 December 2009. This recommendation was based on the risks (especially fenfluramine-like cardiovascular side-effects)...
Investigational
Withdrawn
Matched Iupac: … 2-({1-[3-(trifluoromethyl)phenyl]propan-2-yl}amino)ethyl benzoate …
Caroxazone
Caroxazone is an antidepressant that has been withdrawn from the market. It is a reversible monoamine oxidase inhibitor (MAOI) of both A and B monoamine oxidase subtypes. However, it presents a five-fold preference for the MAO-B subtype.
Withdrawn
Matched Iupac: … 2-(2-oxo-3,4-dihydro-2H-1,3-benzoxazin-3-yl)acetamide …
Buquinolate
Experimental
Vet approved
Matched Iupac: … ethyl 6,7-bis(2-methylpropoxy)-4-oxo-1,4-dihydroquinoline-3-carboxylate …
Equol
Equol has been used in trials studying the treatment of Breast Cancer.
Investigational
Matched Iupac: … (3S)-3-(4-hydroxyphenyl)-3,4-dihydro-2H-1-benzopyran-7-ol …
LY-295501
ILX-295501 has been used in trials studying the treatment of Ovarian Cancer, Metastatic Cancer, Fallopian Tube Cancer, and Primary Peritoneal Cavity Cancer.
Investigational
Matched Iupac: … 1-(3,4-dichlorophenyl)-3-(2,3-dihydro-1-benzofuran-5-sulfonyl)urea …
Terpinen-4-ol
Terpinen-4-ol is under investigation in clinical trial NCT01647217 (Demodex Blepharitis Treatment Study).
Investigational
Matched Iupac: … 4-methyl-1-(propan-2-yl)cyclohex-3-en-1-ol …
Succinylsulfathiazole
Experimental
Matched Iupac: … 3-({4-[(1,3-thiazol-2-yl)sulfamoyl]phenyl}carbamoyl)propanoic acid …
AZD-7325
AZD7325 is a high affinity, selective modulator of the GABAA receptor system.
Investigational
Matched Iupac: … 4-amino-8-(2-fluoro-6-methoxyphenyl)-N-propylcinnoline-3-carboxamide …
Xanomeline
Xanomeline is under investigation in clinical trial NCT02831231 (Pilot Study Comparing Effects of Xanomeline Alone to Xanomeline Plus Trospium).
Investigational
Matched Iupac: … 5-[4-(hexyloxy)-1,2,5-thiadiazol-3-yl]-1-methyl-1,2,3,6-tetrahydropyridine …
FET F-18
FET F-18 is under investigation in clinical trial NCT01756352 (FET-PET for Evaluation of Response of Recurrent GBM to Avastin).
Investigational
Matched Iupac: … (2S)-2-amino-3-{4-[2-(¹⁸F)fluoroethoxy]phenyl}propanoic acid …
Dotinurad
Dotinurad is under investigation in clinical trial NCT03372200 (Febuxostat-controlled, Double-blind, Comparative Study of FYU-981 in Hyperuricemia With or Without Gout).
Investigational
Matched Iupac: … 3-(3,5-dichloro-4-hydroxybenzoyl)-2,3-dihydro-1lambda6,3-benzothiazole-1,1-dione …
Merestinib
Merestinib has been used in trials studying the treatment of Cancer, Solid Tumor, Advanced cancer, ColoRectal Cancer, and Metastatic Cancer, among others.
Investigational
Matched Iupac: … 2-oxo-1,2-dihydropyridine-3-carboxamide ... N-(3-fluoro-4-{[1-methyl-6-(1H-pyrazol-4-yl)-1H-indazol-5-yl]oxy}phenyl)-1-(4-fluorophenyl)-6-methyl- …
Amcasertib
Amcasertib is under investigation in clinical trial NCT02483247 (A Study of BBI503 in Combination With Selected Anti-Cancer Therapeutics in Adult Patients With Advanced Cancer).
Investigational
Matched Iupac: … ylidene]methyl}-1H-pyrrole-3-carboxamide ... (diethylamino)ethyl]-2,4-dimethyl-5-{[(3Z)-2-oxo-5-(2-phenyl-1,3-thiazol-4-yl)-2,3-dihydro-1H-indol-3- …
RO-6870810
RO-6870810 is under investigation in clinical trial NCT02308761 (A Study of RO6870810/TEN-010 in Participants With Acute Myeloid Leukemia and Myelodysplastic Syndrome).
Investigational
Matched Iupac: … (6),4,7,10,12-pentaen-9-yl]-N-[3-(4-methylpiperazin-1-yl)propyl]acetamide ... 2-[(9S)-7-(4-chlorophenyl)-4,5,13-trimethyl-3-thia-1,8,11,12-tetraazatricyclo[8.3.0.0^{2,6}]trideca-2 …
TD-2749
TD-2749 is selective 5-HT4 agonists discovered by Theravance through the application of multivalent drug design in a drug discovery program dedicated to finding new medicines for GI motility disorders such as chronic constipation, constipation-predominant irritable bowel syndrome (C-IBS), opioid-induced constipation, functional dyspepsia and diabetic gastroparesis.
Investigational
Matched Iupac: … -3-carboxamide ... N-[(1R,3S,5S)-8-[2-(4-acetylpiperazin-1-yl)ethyl]-8-azabicyclo[3.2.1]octan-3-yl]-1-(propan-2-yl)-1H-indazole …
SRT-2104
SRT2104 has been investigated for the basic science and treatment of Sepsis, PSORIASIS, Atrophy, Muscular, and Diabetes Mellitus, Type 2.
Investigational
Matched Iupac: … 4-methyl-N-(2-{3-[(morpholin-4-yl)methyl]imidazo[2,1-b][1,3]thiazol-6-yl}phenyl)-2-(pyridin-3-yl)-1,3 …
Timcodar
Timcodar has been used in trials studying the treatment of Unspecified Adult Solid Tumor, Protocol Specific.
Investigational
Matched Iupac: … (2S)-N-benzyl-N-[1,5-bis(pyridin-4-yl)pentan-3-yl]-3-(4-chlorophenyl)-2-[N-methyl-2-oxo-2-(3,4,5-trimethoxyphenyl …
BMS-817399
BMS-817399 is under investigation in clinical trial NCT01404585 (Proof-of-Concept Study With BMS-817399 to Treat Moderate to Severe Rheumatoid Arthritis).
Investigational
Matched Iupac: … 1-[(2R)-1-[(4S)-4-(4-chlorophenyl)-4-hydroxy-3,3-dimethylpiperidin-1-yl]-3-methyl-1-oxobutan-2-yl]-3- …
Displaying drugs 8176 - 8200 of 9513 in total