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Displaying drugs 801 - 825 of 1068 in total

Olesoxime

Olesoxime is a cholesterol-like small molecule that has demonstrated a remarkable neuroprotective profile in a battery of both in vitro and in vivo preclinical models. For example, it has demonstrated the ability to prevent neurodegeneration, enhance nerve function and accelerate neuroregeneration following nerve trauma.[A3282,A253233]
Investigational
Matched Synonyms: … 4-Cholesten-3-one, oxime ... cholest-4-en-3-one, oxime …
Matched Description: … small molecule that has demonstrated a remarkable neuroprotective profile in a battery of both in vitro and ... For example, it has demonstrated the ability to prevent neurodegeneration, enhance nerve function and …

Diatrizoate

A commonly used x-ray contrast medium. As diatrizoate meglumine and as Diatrizoate sodium, it is used for gastrointestinal studies, angiography, and urography.
Approved
Vet approved
Matched Description: … As diatrizoate meglumine and as Diatrizoate sodium, it is used for gastrointestinal studies, angiography ... , and urography. …
Matched Mixtures name: … Diatrizoate Meglumine and Diatrizoate Sodium ... Diatrizoate Meglumine and Diatrizoate Sodium ... Diatrizoate Meglumine and Diatrizoate Sodium …
Matched Salts name: … Diatrizoate sodium …
Matched Products: … Hypaque Sodium ... Hypaque Sodium 50% Liq ... Hypaque Sodium Liq 50% …

Sodium cellulose phosphate

Sodium cellulose phosphate is used to treat hypercalcemia and hypercalciuria. It has been used to prevent kidney stones. This compound is an ion-exchange resin that can not be absorbed by the body. However, it can be used to restore normal intestinal calcium absorption.
Approved
Matched Synonyms: … Cellulose sodium phosphate …
Matched Name: … Sodium cellulose phosphate …
Matched Description: … Sodium cellulose phosphate is used to treat hypercalcemia and hypercalciuria. …
Matched Categories: … sodium cellulose phosphate …

Oxyquinoline

Oxyquinoline is a heterocyclic phenol and derivative of quinoline with antiseptic, disinfectant, and pesticide properties. It is used as a stabilizer for hydrogen peroxide, where it is sometimes added in cosmetic products.
Approved
Vet approved
Matched Synonyms: … oxine …
Matched Description: … Oxyquinoline is a heterocyclic phenol and derivative of quinoline with antiseptic, disinfectant, and …
Matched Categories: … Alimentary Tract and Metabolism ... Antiseptics and Disinfectants ... Antiinfectives and Antiseptics for Local Oral Treatment ... Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics …

Bismuth subnitrate

Bismuth subnitrate, also referred to as bismuth oxynitrate or bismuthyl nitrate, is a highly water-soluble crystalline compound that has been used as a treatment for duodenal ulcers and anti-diarrheic agent . The use of bismuth substrate as an active ingredient in over-the-counter antacids is approved by the FDA.
Approved
Matched Synonyms: … Bismuth hydroxide nitrate oxide …
Matched Description: … is a highly water-soluble crystalline compound that has been used as a treatment for duodenal ulcers and …
Matched Categories: … Alimentary Tract and Metabolism ... Drugs for Peptic Ulcer and Gastro-Oesophageal Reflux Disease (Gord) …

6'-Methyl-Thiamin Diphosphate

Experimental
Matched Name: … 6'-Methyl-Thiamin Diphosphate …

Prednisolone phosphate

Prednisolone phosphate is a glucocorticoid similar to cortisol used for its anti-inflammatory, immunosuppressive, anti-neoplastic, and vasoconstrictive effects. Prednisolone phosphate was granted FDA Approval on 19 December 1973.
Approved
Vet approved
Matched Description: … glucocorticoid similar to [cortisol] used for its anti-inflammatory, immunosuppressive, anti-neoplastic, and …
Matched Mixtures name: … Sulfacetamide Sodium and Prednisolone Sodium Phosphate ... Sulfacetamide Sodium and Prednisolone Sodium Phosphate ... Sulfacetamide Sodium and Prednisolone Sodium Phosphate …
Matched Salts name: … Prednisolone sodium phosphate …
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … Prednisolone Sodium Phosphate ... Prednisolone Sodium Phosphate ODT ... Minims Prednisolone Sodium Phosphate …

Sodium lauryl sulfoacetate

Sodium lauryl sulfoacetate is a wetting agent and surfactant used in enema-type laxative products.
Approved
Experimental
Matched Synonyms: … Sulfoacetic acid dodecyl ester S-sodium salt …
Matched Name: … Sodium lauryl sulfoacetate …
Matched Iupac: … sodium 2-(dodecyloxy)-2-oxoethane-1-sulfonate …
Matched Description: … Sodium lauryl sulfoacetate is a wetting agent and surfactant used in enema-type laxative products. …
Matched Categories: … Alimentary Tract and Metabolism ... sodium lauryl sulfoacetate, incl. combinations …

(S)-4-Nitrostyrene oxide

Experimental
Matched Name: … (S)-4-Nitrostyrene oxide …

Atractylodes japonica root oil

Atractylodes japonica root oil is obtained from the roots of Atractylodes japonica, which is a herb native to eastern Asia. It is present in some cosmetic products such as whitening creams as an active ingredient and lubricant for skin irritation. Atractylodes japonica is reported to have anti-inflammatory and antinociceptive effects...
Experimental
Matched Name: … Atractylodes japonica root oil …
Matched Description: … It is present in some cosmetic products such as whitening creams as an active ingredient and lubricant ... Atractylodes japonica is reported to have anti-inflammatory and antinociceptive effects [A27223]. ... Atractylodes japonica root oil is obtained from the roots of Atractylodes japonica, which is a herb native …

Bevacizumab

There is a great deal of evidence indicating that vascular endothelial growth factor (VEGF) is important for the survival and proliferation of cancer cells.[A192939,A192837,A192891,A193275] VEGF plays an important role in angiogenesis, lymphangiogenesis, and tumor growth, which are all factors that contribute to its attractiveness as a therapeutic target for anti-cancer...
Approved
Investigational
Matched Synonyms: … rhuMAb-VEGF …
Matched Description: … of evidence indicating that vascular endothelial growth factor (VEGF) is important for the survival and ... [A193272,A193275] It is a humanized monoclonal IgG antibody, and inhibits angiogenesis by binding and ... [A192939,A192837,A192891,A193275] VEGF plays an important role in angiogenesis, lymphangiogenesis, and …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES …

Formoterol

Formoterol is an inhaled beta2-agonist used in the management of COPD and asthma that was first approved for use in the United States in 2001. It acts on bronchial smooth muscle to dilate and relax airways, and is administered as a racemic mixture of its active (R;R)- and inactive (S;S)-enantiomers....
Approved
Investigational
Matched International brands: … Oxis Turbuhaler …
Matched Description: … [A189528] A major clinical advantage of formoterol over other inhaled beta-agonists is its rapid onset ... [L10986] It acts on bronchial smooth muscle to dilate and relax airways, and is administered as a racemic ... Formoterol is an inhaled beta2-agonist used in the management of COPD and asthma that was …
Matched Mixtures name: … Budesonide and Formoterol Fumarate Dihydrate ... Budesonide and Formoterol Fumarate Dihydrate ... Budesonide and Formoterol Fumarate Dihydrate …
Matched Categories: … formoterol and mometasone ... formoterol and budesonide ... formoterol and aclidinium bromide ... formoterol and fluticasone ... formoterol and beclometasone …
Matched Products: … OXIS ... OXIS TURBOHALER 6UG 60ED ... OXIS TURBUHALER 6UG 60ED …

Trastuzumab

Produced in CHO cell cultures, trastuzumab is a recombinant IgG1 kappa, humanized monoclonal antibody that selectively binds with high affinity in a cell-based assay (Kd = 5 nM) to the extracellular domain of the human epidermal growth factor receptor protein (HER2). It is used as a treatment of human epidermal...
Approved
Investigational
Matched Synonyms: … RHUMAB HER2 …
Matched Description: … Trastuzumab binds to HER2 and suppresses cancer cell growth, proliferation, and survival directly and ... that the overexpression or gene amplification of HER2 has been found in about 20–30% of breast cancers and …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... pertuzumab and trastuzumab ... MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES …

Fosphenytoin

Fosphenytoin is a water-soluble phenytoin prodrug used only in hospitals for the treatment of epileptic seizures. It works by slowing down impulses in the brain that cause seizures. Its main mechanism is to block frequency-dependent, use-dependent and voltage-dependent neuronal sodium channels, and therefore limit repetitive firing of action potentials.
Approved
Investigational
Matched Description: … Its main mechanism is to block frequency-dependent, use-dependent and voltage-dependent neuronal sodium ... channels, and therefore limit repetitive firing of action potentials. …
Matched Salts name: … Fosphenytoin sodium …
Matched Categories: … Phenytoin and Prodrugs ... Sodium Channel Blockers …
Matched Products: … Fosphenytoin Sodium ... Fosphenytoin sodium …

Secobarbital

Secobarbital (marketed by Eli Lilly and Company under the brand names Seconal and Tuinal) is a barbiturate derivative drug with anaesthetic, anticonvulsant, sedative and hypnotic properties. It is commonly known as quinalbarbitone in the United Kingdom.
Approved
Vet approved
Matched Description: … Secobarbital (marketed by Eli Lilly and Company under the brand names Seconal and Tuinal) is a barbiturate ... derivative drug with anaesthetic, anticonvulsant, sedative and hypnotic properties. …
Matched Salts name: … Secobarbital sodium …
Matched Categories: … Hypnotics and Sedatives …
Matched Products: … Seconal Sodium ... Seconal Sodium Pulvule 240 0.1gm …

Cyclophosphamide

Precursor of an alkylating nitrogen mustard antineoplastic and immunosuppressive agent that must be activated in the liver to form the active aldophosphamide. It has been used in the treatment of lymphoma and leukemia. Its side effect, alopecia, has been used for defleecing sheep. Cyclophosphamide may also cause sterility, birth defects,...
Approved
Investigational
Matched Synonyms: … 2-[Bis(2-chloroethylamino)]-tetrahydro-2H-1,3,2-oxazaphosphorine-2-oxide ... N,N-Bis(2-chloroethyl)tetrahydro-2H-1,3,2-oxazaphosphorin-2-amine 2-oxide ... (±)-2-(BIS(2-CHLOROETHYL)AMINO)TETRAHYDRO-2H-1,3,2-OXAZAPHOSPHORINE 2-OXIDE MONOHYDRATE …
Matched Description: … Precursor of an alkylating nitrogen mustard antineoplastic and immunosuppressive agent that must be activated ... It has been used in the treatment of lymphoma and leukemia. ... Cyclophosphamide may also cause sterility, birth defects, mutations, and cancer. …
Matched Categories: … Antineoplastic and Immunomodulating Agents …

Brinzolamide

Brinzolamide is a highly specific, non-competitive, reversible carbonic anhydrase II (CA-II) inhibitor indicated to reduce ocular pressure in patients with ocular hypertension or open-angle glaucoma. Although the exact pathophysiology of glaucoma is still unknown, one of the main hallmarks of this disease is vascular dysregulation and abnormalities.[A2049,A2051] The resulting vascular...
Approved
Matched Iupac: … (4R)-4-(ethylamino)-2-(3-methoxypropyl)-1,1-dioxo-2H,3H,4H-1lambda6-thieno[3,2-e][1,2]thiazine-6-sulfonamide …
Matched Description: … pathophysiology of glaucoma is still unknown, one of the main hallmarks of this disease is vascular dysregulation and ... ], the first-ever approved topical CA inhibitor with contrasting results and evidence. ... [A2049,A2051] Brinzolamide was developed as a topical solution to the systemic side effects and [dorzolamide …
Matched Categories: … Antiglaucoma Preparations and Miotics ... Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics …
Matched Products: … AZOPT 10MG/ML AUGENTR SUSP ... AZOPT 10MG/ML AUGENTRO SUS …

Potassium hydrogen DL-aspartate

Experimental
Matched Name: … Potassium hydrogen DL-aspartate …
Matched Iupac: … potassium 3-amino-3-carboxypropanoate …

Neoarsphenamine

Investigational
Withdrawn
Matched Synonyms: … Sodium p,p'-dihydroxy-m,m'-diaminoarsenobenzene-n-monomethanol sulfoxylate ... Sulfoxylic acid, mono(((5-((3-amino-4-hydroxyphenyl)diarsenyl)-2-hydroxyphenyl)amino)methyl) ester, sodium …
Matched Iupac: … sodium {[({5-[(1E)-2-(3-amino-4-hydroxyphenyl)diarsen-1-yl]-2-hydroxyphenyl}amino)methoxy]sulfanyl}olate …

Alendronic acid

Alendronic acid is a second generation bisphosphonate that is used for the treatment of some forms of osteoperosis and Paget's disease[FDA Label][A959,A203111]. It functions by preventing resorption of bone[FDA Label] .
Approved
Matched International brands: … Alned …
Matched Description: … is a second generation bisphosphonate that is used for the treatment of some forms of osteoperosis and …
Matched Salts name: … Alendronate sodium ... Alendronate sodium anhydrous …
Matched Categories: … Drugs Affecting Bone Structure and Mineralization ... alendronic acid and colecalciferol ... alendronic acid and alfacalcidol, sequential ... alendronic acid, calcium and colecalciferol, sequential …
Matched Products: … ALOST ... Alendronate Sodium ... Ag-alendronate Sodium …

Fenbendazole

Fenbendazole is a benzimidazole that presents a wide spectrum anthelmintic effect. It is used against a number of gastrointestinal parasites including giardia, roundworms, hookworms, whipworms, the Taenia genus of tapeworms, pinworms, aelurostrongylus, paragonimiasis, strongyles, and Strongyloides. Fenbendazole is approved to be administered under veterinary to sheep, cattle, horses, fish, dogs,...
Vet approved
Matched Synonyms: … Methyl [5-(phenylthio)-1H-benzimidazol-2-yl]carbamate …
Matched Iupac: … methyl N-[5-(phenylsulfanyl)-1H-1,3-benzodiazol-2-yl]carbamate …
Matched Description: … , whipworms, the Taenia genus of tapeworms, pinworms, aelurostrongylus, paragonimiasis, strongyles, and ... is approved to be administered under veterinary to sheep, cattle, horses, fish, dogs, cats, rabbits and …
Matched Categories: … Antiparasitic Products, Insecticides and Repellents …

Amphotericin B

Amphotericin B shows a high order of in vitro activity against many species of fungi. Histoplasma capsulatum, Coccidioides immitis, Candida species, Blastomyces dermatitidis, Rhodotorula, Cryptococcus neoformans, Sporothrix schenckii, Mucor mucedo, and Aspergillus fumigatus are all inhibited by concentrations of amphotericin B ranging from 0.03 to 1.0 mcg/mL in vitro. While...
Approved
Investigational
Matched Description: … Blastomyces dermatitidis, Rhodotorula, Cryptococcus neoformans, Sporothrix schenckii, Mucor mucedo, and ... The antibiotic is without effect on bacteria, rickettsiae, and viruses. ... Pseudallescheria boydii and Fusarium sp. are often resistant to amphotericin B. …
Matched Categories: … Alimentary Tract and Metabolism ... Antiinfectives and Antiseptics for Local Oral Treatment ... Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics …
Matched Products: … SUS. ICEREN FLAKON, 1 ADET …

EF-022

EF-022 is a modified version of vitamin D binding protein macrophage activator, with potential antineoplastic and anti-angiogenic activities.
Investigational
Matched Synonyms: … Modified Vitamin D Binding Protein Macrophage Activator …
Matched Description: … and anti-angiogenic activities. ... EF-022 is a modified version of vitamin D binding protein macrophage activator, with potential antineoplastic …

6-bromoindirubin-3'-oxime

Experimental
Matched Synonyms: … (2Z,3E)-6-Bromoindirubin-3'-oxime ... (2Z,3E)-6'-bromo-2,3'-biindole-2',3(1H,1'H)-dione 3-oxime …
Matched Name: … 6-bromoindirubin-3'-oxime …

Pyridoxal-5'-Phosphate-N-Oxide

Experimental
Matched Name: … Pyridoxal-5'-Phosphate-N-Oxide …
Displaying drugs 801 - 825 of 1068 in total